Best Operating Grants for Nonprofits in Florida

The Peacock Foundation Inc. grants support the health and well-being of South Florida's children and families through contributions to eligible 501(c)(3) public charities. The foundation prioritizes proposals that address human services, education, health, youth, elderly care, disabilities, arts for educational purposes, and environmental education. All applicants must submit a letter of inquiry detailing their mission, project description, community served, and funding request. The foundation does not fund capital campaigns, individuals, or lobbying efforts.

The Santander Charitable Sponsorship Program focuses on supporting low- to moderate-income communities primarily in the Northeast and Florida. With a commitment of $100 million in charitable giving, the program addresses key community development needs, including affordable housing, job creation, financial education, and disaster relief. Eligible organizations must have IRS 501(c)(3) status or be public agencies, demonstrating capacity to meet community needs. Unsolicited applications are not accepted.

The Social Impact Fund - Nationwide Grant supports innovative solutions addressing health care access, food security, and economic empowerment. Funded by the American Heart Association, this grant prioritizes community-led projects from organizations with under $10M in revenue. Eligible entities include both for-profit and nonprofit organizations based in the U.S. and Puerto Rico. Grants can provide up to $250,000 to initiatives that demonstrate measurable impact, fostering sustainable change in health and wellness.

The SECO Energy Foundation Grant aims to improve community quality of life through charitable initiatives. As a 501(c)(3) nonprofit, it supports educational, environmental, energy-related, veteran, public safety, and health projects. Grants are available in two tiers: Community Grants, up to $25,000, and Mini-Grants, up to $5,000. Eligible organizations must serve SECO territories in Florida and meet specific criteria, ensuring that funding directly benefits local residents.

The Penn National Gaming Foundation Grants support various community initiatives across North America, emphasizing education, health services, and cultural affairs. Launched post-Hurricane Katrina, the foundation aids local nonprofits, enhancing community development, public safety, and veteran support. The grants cater to organizations that address the needs of children, senior citizens, and disadvantaged populations, ensuring a broad impact in areas where Penn National Gaming operates. This commitment reflects the foundation's dedication to uplifting communities and fostering resilience.

The Corporate Giving Program by the Franklin P. and Arthur W. Perdue Foundation focuses on supporting nonprofit organizations within specific states. They prioritize initiatives that enhance community welfare, especially in agriculture, education, health, and environmental sustainability. Organizations must have 501(c)(3) status to apply, and preference is given to those involving Perdue associates. Ineligible requests include those from religious, political, or individual-focused groups. This program emphasizes broad community benefits over organizational affiliations.

The North Carolina GlaxoSmithKline Foundation offers Traditional Grants starting at $25,000 to nonprofit organizations addressing educational and health needs. Established in 1986, the Foundation has awarded over $90 million in grants, focusing on seed funding for innovative programs. Applications are accepted quarterly, with a preference for initiatives that can have a broader impact beyond local communities. The Foundation only funds 501(c)(3) organizations and excludes certain operational costs.

The Dunspaugh-Dalton Foundation Grant supports nonprofits focused on charitable, educational, and cultural initiatives primarily in Miami-Dade County, Florida, and Monterey County, California. New applicants must submit a Letter of Intent, while returning applicants can directly submit proposals. The foundation prioritizes projects with clearly defined outcomes in areas like arts, education, health care, and community services. Grants are typically awarded for one year, promoting impactful community improvements.

The Wawa Foundation offers financial grants exceeding $2,500 to 501(c)(3) non-profit organizations in its six-state market, focusing on health, hunger, and supporting everyday heroes. Applications are accepted in January, April, July, and October, with grant requests reviewed prior to the next submission window. Eligible organizations include those working to improve lives through health initiatives, hunger relief efforts, and support for community heroes. For more details, visit the Wawa Foundation's official site.

The Scaife Family Foundation Grant has been supporting vulnerable community members for nearly 40 years, providing over $180 million in donations to non-profits. The Foundation aims to match organizations with aligned goals, focusing on women and children, addiction prevention, and animal welfare. It offers grants for general operating and program support, prioritizing impactful programs that address societal issues. Notably, the Foundation considers proposals that foster healthy relationships and promote treatment for addiction, enhancing the welfare of both humans and animals.

The Stellar Foundation Grants support 501(c)(3) non-profit organizations focused on enhancing healthcare, education, cultural events, and community services. Established by the Stellar Foundation in 2006, these grants encourage employee engagement in philanthropy and community development. Applications are accepted quarterly, with a focus on projects that demonstrate clear goals and community impact. Organizations must possess the necessary resources to implement their initiatives effectively.

The Cigna Foundation is dedicated to enhancing veteran mental health through strategic partnerships with nonprofit organizations. This initiative targets the alarming issue of homelessness among veterans, with nearly 40,000 veterans without shelter nightly and 1.5 million at risk. By funding evidence-informed programs, the foundation aims to increase access to permanent housing, improve affordability, and provide essential wraparound services, ultimately fostering mental health stability and resilience within veteran communities.

The Dr. P. Phillips Legacy Microgrant Program, supported by Dr. Phillips Charities, offers annual grants of $5,000 to 15 nonprofit organizations in Central Florida. Prioritizing projects that alleviate economic pressures on low-income families or enhance literacy, it seeks to foster community support and lasting impact. Eligible nonprofits must be based in Orange or Osceola Counties and have been operational for at least two years. This initiative honors the Phillips family's legacy of helping others help themselves.

The Champions in Action Grant, offered by the Citizens Charitable Foundation, supports nonprofit organizations in California, Massachusetts, New Jersey, New York City, Pennsylvania, Rhode Island, and Southern Florida. This funding, totaling $50,000, aims to empower nonprofits addressing social challenges through innovative solutions. With an application deadline extended to August 22, 2025, eligible organizations can gain not only financial support but also media coverage and volunteer assistance to enhance their community impact.

South Arts, Inc. is offering Accessibility Grants of up to $2,500 to nonprofit organizations in the Southeast to enhance accessibility in arts programs for individuals with disabilities. The grants aim to foster inclusivity by supporting projects that engage disabled artists and audiences. Organizations must be located within the South Arts Service region and focus on the arts. Priority will be given to new applicants and those serving BIPOC and LGBTQIA+ communities, with a commitment to rural areas.

IMPACT the Palm Beaches is a philanthropic organization empowering women to fund transformative grants for nonprofits in Central and Northern Palm Beach County. Each year, members contribute to award grants totaling $100,000, fostering community growth. The organization focuses on vital areas such as Arts & Culture, Education, Environment, Family, and Health & Wellness. Since 2015, over $1.9 million has been invested in impactful projects, enhancing local services and support for underserved populations.

The Hancock Whitney Opportunity Grant, in collaboration with the Greater New Orleans Foundation, invites applications from eligible nonprofits starting October 7, 2025. This grant aims to enhance capacity building and sustainability for organizations focused on food insecurity, workforce development, and youth programs. Eligible applicants include 501(c)(3) organizations serving low to moderate-income communities within Hancock Whitney's service areas, fostering impactful changes with AmeriCorps support.

The American Honda Foundation provides programmatic support to nonprofit organizations and schools in the U.S., empowering impactful initiatives aligned with community needs. Funding opportunities are available through Honda corporate and Honda USA Foundation, focusing on projects that enhance education and community welfare. Eligible organizations must have nonprofit status or be recognized educational institutions. The application process opens each fall, with funding decisions announced the following spring, ensuring alignment with Honda's commitment to social responsibility.

The Programmatic Support - Education Pillar Award by Honda aims to enhance workforce readiness in the manufacturing sector. It supports nonprofit organizations and schools focused on hands-on programs in design, software/data analytics, and AI/machine learning. Eligible applicants must be US-based and have 501(c)(3) status. The initiative prioritizes projects that train individuals for manufacturing roles, develop technical skills, and introduce automation to prepare for evolving industry demands, ultimately fostering economic prosperity in local communities.

The Honda USA Foundation's Mobility Pillar Award aims to empower individuals with disabilities by funding programs that enhance access and mobility. The foundation supports nonprofit organizations and schools that provide therapeutic, adaptive, and comprehensive care programs, as well as mobility modifications and assistive technology. Applications are accepted from U.S.-based organizations with 501(c)(3) status or fiscal sponsors, ensuring that the joy of mobility is accessible to all.

The Elevance Health Foundation's Behavioral Health Grant aims to address significant challenges in mental health and substance use disorders. With a commitment of up to $90 million over three years, the Foundation seeks partnerships with nonprofits to enhance treatment access, promote prevention strategies, and alleviate loneliness among affected individuals. This initiative emphasizes innovative solutions and measurable outcomes, targeting both national and local programs, particularly in states with pressing health disparities.

The City of Orlando's Community Investment Program offers approximately $2.4 million in grants to support non-profit organizations providing essential services to residents within city limits. Eligible organizations must demonstrate effective service capabilities, fiscal strength, and a commitment to addressing community needs through various focus areas, including housing assistance, family sustainability, and domestic violence prevention. Special consideration is given to grassroots organizations that serve underrepresented communities, enhancing equity and access to vital resources.

The Florida Blue Foundation's Driver of Health: Food Security Grants aim to enhance food security for families in vulnerable communities. By improving access to affordable, nutritious food, the initiative seeks to mitigate health risks associated with food insecurity. Eligible applicants include nonprofit organizations and community agencies in Florida, focusing on educational programs that promote self-sufficiency. Priority will be given to areas with high food insecurity, ensuring that targeted populations receive essential support.

The Comcast NBCUniversal Foundation offers Local Impact Grants to nonprofit organizations in 11 markets, providing $225,000 to support local programs addressing community issues. Eligible organizations must be 501(c)(3) nonprofits with a revenue exceeding $100,000 and must operate in one of the specified television markets. The grants aim to empower youth through education, promote diverse storytelling, and enhance community engagement. This initiative underscores Comcast's commitment to fostering inclusion and equitable opportunities for underserved communities.

The Hubert E. Sapp Regular Grant Cycle, by Southern Partners Fund, aims to empower rural communities in the Southeastern U.S. through grassroots leadership and organizing. The fund provides support to nonprofit organizations focused on social, economic, and environmental justice. Eligible applicants are community-based organizations with budgets under $350,000. The initiative honors Hubert E. Sapp's legacy, promoting equitable relationships that drive real transformation and community decision-making.

The Elevance Health Foundation's Food as Medicine Grant aims to enhance access to nutritious foods and improve health outcomes for individuals facing diet-related conditions. This initiative invites qualified nonprofits to submit proposals focused on scalable solutions that address food insecurity and promote health equity. The foundation prioritizes programs that demonstrate measurable outcomes and support whole-person health, particularly for populations at high social risk. Grants will be awarded for a term of 1-3 years, with funding based on program needs.