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Best Operating Grants for Nonprofits in Florida

Find the perfect Operating grants for nonprofits in Florida on Instrumentl. 300+ Operating grants for nonprofits in Florida in the United States.

255

Available grants

$73.1M

Total funding

$12.5K

Median grant

255 grants
$73.1M total
$12.5K median

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Last updated: October 5, 2026. Next update: November 1, 2026.

AI summary from publicly available grant information

Approximately US $25,000

Advocare Foundation Grants

Applications due Jun 5, 2027
The AdvoCare Foundation, established in 1993, aims to promote health and wellness for children through its grant program. Focused on year-round initiatives, the foundation supports local communities where AdvoCare distributors operate. Grants typically last one year with an average funding of $25,000, although multi-year support may be available. The foundation prioritizes programs that foster positive health changes and encourages collaborative efforts with previous grantees.
Advocare Foundation

Up to US $100,000

Ed and Ethel Moore Alzheimer's Disease Research Program: Multi-Vitamin - Postdoctoral Research Fellowship Grant

Applications due Oct 20, 2026

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

Ed and Ethel Moore Alzheimer's Disease Research Program: Multi-Vitamin

Research Focus

The purpose of this announcement is to stimulate research activities that study the impact of daily vitamin use on the improvement of cognitive function and any associated health care cost impacts on populations over the age of 65.

Funding Information

Applicants must request funding in the following grant categories to pursue research in the area of focus outlined in the Research Focus section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category to pursue the area of focus from the Research Focus section of this FOA.   

The grant categories are: 1) Consortium Grant; 2) Standard Grant; 3) Pilot Grant; 4) Postdoctoral Research Fellowship Grant

Grant Categories: Postdoctoral Research Fellowship Grant

Grants support the career development of individuals who have made a commitment to focus their research endeavors on research oriented to clinical service, evaluation, neurochemistry, neurosciences, neuromedicine, neurotherapeutics, neuropharmacology, neuropathology, etc. Research organizations are eligible to apply for no more than one Postdoctoral Research Fellowship Grant.

Florida Department of Health

Up to US $100,000

FBCF: Scientific Research Grant - Pilot Program

Letter of inquiry due Dec 12, 2026
The Florida Breast Cancer Foundation (FBCF) offers the Scientific Research Grant - Pilot Program, providing up to $100,000 for innovative breast cancer research. This initiative emphasizes collaborative projects that address critical areas such as environmental links to breast cancer, translational research, and psycho-immunological studies. FBCF aims to support new investigators and multidisciplinary teams to transform breast cancer treatment and understanding, ultimately striving for a significant impact on outcomes for patients in Florida.
Florida Breast Cancer Foundation

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Up to US $250,000

Live Like Bella Pediatric Cancer Research Initiative: Discovery Science Category

Pre proposal due Nov 30, 2026

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

The Live Like Bella Pediatric Cancer Research Initiative

The Florida Department of Health’s Live Like Bella Pediatric Cancer Research Initiative supports the pursuit of identifying cures for pediatric cancer.

The Live Like Bella Pediatric Cancer Research Initiative is established in section 381.922, Florida Statutes, works to advance progress toward curing pediatric cancer through grants awarded through a peer-reviewed, competitive process, to:

  • Significantly expand pediatric cancer research capacity in Florida
  • Improve both research and treatment through greater pediatric enrollment in clinical trials networks
  • Reduce the impact of pediatric cancer on disproportionately impacted individuals

Research Focus

Applications submitted in response to this Funding Opportunity Announcement (FOA) must be responsive to one of the following areas of focus. 

  • Prevention and Treatment
  • Screening
  • Obesity
  • Treatment-Related Morbidities
  • Technology Transfer Feasibility (TTF)
  • Investigational New Drug or Investigational Device Exemption

Efforts to foster collaborations among institutions, researchers, and community practitioners should be included, when possible. Preference will be given to applications that address at least one of the cancers listed in the Research Priorities section of this FOA.

Funding Information

Applicants must request funding in the preceding grant categories to pursue research in the areas of focus outlined in the Research Focus section of this FOA. Preference will be given to applications that address the priorities listed in the Research Priorities section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category (depending on the grant program) to pursue an area of focus from the Research Focus section of this FOA. Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding. 

The grant categories are: 1) Bridge; 2) Discovery Science; 3) Emerging Therapeutics and Technologies; 4) Equipment; 5) Multicenter Clinical Trials; 6) New Investigator Research (NIR); 7) High-Risk, High-Reward Clinical Research; 8) High-Risk, High-Reward Discovery Science; 9) Non-Typical Clinical Trials/Socio-Behavioral Research; 10) Research Infrastructure

Bella Initiative Grant Categories: Discovery Science

Discovery science means fundamental theoretical or experimental investigative research to advance knowledge without a specifically envisaged or immediately practical application. Directed to understanding the events related to the development of cancer at the molecular, cellular, and organismic levels, as well as the discovery and development of new drugs or therapies. This section includes studies on basic biology of e-cigarettes. Applications under this mechanism can include observational or cross-sectional studies not involving a clinical trial. Outcome measures can be self-reported, observational, behavioral, biologic, or genetic.

Maximum Duration: 36 months

Florida Department of Health

Up to US $600,000

Live Like Bella Pediatric Cancer Research Initiative: Emerging Therapeutics and Technologies Category

Pre proposal due Nov 30, 2026

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

The Live Like Bella Pediatric Cancer Research Initiative

The Florida Department of Health’s Live Like Bella Pediatric Cancer Research Initiative supports the pursuit of identifying cures for pediatric cancer.

The Live Like Bella Pediatric Cancer Research Initiative is established in section 381.922, Florida Statutes, works to advance progress toward curing pediatric cancer through grants awarded through a peer-reviewed, competitive process, to:

  • Significantly expand pediatric cancer research capacity in Florida
  • Improve both research and treatment through greater pediatric enrollment in clinical trials networks
  • Reduce the impact of pediatric cancer on disproportionately impacted individuals

Research Focus

Applications submitted in response to this Funding Opportunity Announcement (FOA) must be responsive to one of the following areas of focus. 

  • Prevention and Treatment
  • Screening
  • Obesity
  • Treatment-Related Morbidities
  • Technology Transfer Feasibility (TTF)
  • Investigational New Drug or Investigational Device Exemption

Efforts to foster collaborations among institutions, researchers, and community practitioners should be included, when possible. Preference will be given to applications that address at least one of the cancers listed in the Research Priorities section of this FOA.

Funding Information

Applicants must request funding in the preceding grant categories to pursue research in the areas of focus outlined in the Research Focus section of this FOA. Preference will be given to applications that address the priorities listed in the Research Priorities section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category (depending on the grant program) to pursue an area of focus from the Research Focus section of this FOA. Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding. 

The grant categories are: 1) Bridge; 2) Discovery Science; 3) Emerging Therapeutics and Technologies; 4) Equipment; 5) Multicenter Clinical Trials; 6) New Investigator Research (NIR); 7) High-Risk, High-Reward Clinical Research; 8) High-Risk, High-Reward Discovery Science; 9) Non-Typical Clinical Trials/Socio-Behavioral Research; 10) Research Infrastructure

Bella Initiative Grant Categories: Emerging Therapeutics and Technologies

This grant category supports research on emerging therapeutics and technologies used in the diagnosis and treatment of cancer and tobacco-related diseases. Examples include but are not limited to personalized/precision medicine therapies, immunotherapy, gene therapy, repurposing of previously used medications, use of artificial intelligence (AI) in diagnosis and treatment, and comparative effectiveness trials of emerging treatments.

Maximum Duration: 36 months

Florida Department of Health

Up to US $250,000

Live Like Bella Pediatric Cancer Research Initiative: Non-Typical Clinical Trials/Socio-Behavioral Research Category

Pre proposal due Nov 30, 2026

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

The Live Like Bella Pediatric Cancer Research Initiative

The Florida Department of Health’s Live Like Bella Pediatric Cancer Research Initiative supports the pursuit of identifying cures for pediatric cancer.

The Live Like Bella Pediatric Cancer Research Initiative is established in section 381.922, Florida Statutes, works to advance progress toward curing pediatric cancer through grants awarded through a peer-reviewed, competitive process, to:

  • Significantly expand pediatric cancer research capacity in Florida
  • Improve both research and treatment through greater pediatric enrollment in clinical trials networks
  • Reduce the impact of pediatric cancer on disproportionately impacted individuals

Research Focus

Applications submitted in response to this Funding Opportunity Announcement (FOA) must be responsive to one of the following areas of focus. 

  • Prevention and Treatment
  • Screening
  • Obesity
  • Treatment-Related Morbidities
  • Technology Transfer Feasibility (TTF)
  • Investigational New Drug or Investigational Device Exemption

Efforts to foster collaborations among institutions, researchers, and community practitioners should be included, when possible. Preference will be given to applications that address at least one of the cancers listed in the Research Priorities section of this FOA.

Funding Information

Applicants must request funding in the preceding grant categories to pursue research in the areas of focus outlined in the Research Focus section of this FOA. Preference will be given to applications that address the priorities listed in the Research Priorities section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category (depending on the grant program) to pursue an area of focus from the Research Focus section of this FOA. Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding. 

The grant categories are: 1) Bridge; 2) Discovery Science; 3) Emerging Therapeutics and Technologies; 4) Equipment; 5) Multicenter Clinical Trials; 6) New Investigator Research (NIR); 7) High-Risk, High-Reward Clinical Research; 8) High-Risk, High-Reward Discovery Science; 9) Non-Typical Clinical Trials/Socio-Behavioral Research; 10) Research Infrastructure

Bella Initiative Grant Categories: Non-Typical Clinical Trials/Socio-Behavioral Research

Research in this mechanism of support encompasses studies using innovative methodologies beyond traditional randomized controlled trials, including adaptive designs, observational studies, behavioral interventions, implementation science, digital health approaches, and research examining psychosocial factors affecting prevention, treatment, and outcomes.

Maximum Duration: 36 months

Florida Department of Health

Up to US $500,000

Special Category Grants

Applications due Jun 1, 2027
The Special Category Grants program, administered by the Florida Department of State's Division of Historical Resources, offers funding for significant historic preservation initiatives. This competitive grant program supports projects such as the preservation and rehabilitation of historic properties, archaeological research, and museum exhibit development. While funding is not guaranteed, it aims to promote appreciation and knowledge of Florida's rich history through various preservation efforts.
Florida Department of State: Division of Historical Resources

US $10,000 - US $500,000

Rural Business Development Grants in Florida

Applications due Jun 15, 2027
The Rural Business Development Grants in Florida aim to support small rural businesses with training and technical assistance. These grants are available for projects benefiting areas with populations under 50,000, focusing on enterprise and opportunity grants. Funds can be used for various purposes, including business planning, infrastructure development, and community economic growth. Prioritization is given to smaller funding requests, enhancing the potential for impactful local development.
USDA: Rural Development (RD)

Up to US $50,000

Arthur F. and Alice E. Adams Charitable Foundation Grant

Applications due Feb 15, 2027
The Arthur F. and Alice E. Adams Charitable Foundation, established in 1985, supports various charitable initiatives focusing on arts, culture, humanities, and education. It primarily benefits organizations in Memphis, Miami, and New York City. Eligible applicants must be 501(c)(3) exempt organizations and seek project sponsorships. The foundation does not fund general operating costs or capital campaigns, and requests over $50,000 are generally discouraged. Proposals must be for projects commencing at least a year after submission.
Arthur F And Alice E Adams Supporting Foundation

US $25,000 - US $65,000

Connecting Joy Grant

Applications due Jun 5, 2027
The Connecting Joy Grant, provided by the Joy in Childhood Foundation, aims to enhance the hospital experience for children battling illness through engaging gaming programs. This initiative supports children's hospitals and nonprofits by funding equipment, staffing, and connectivity, ensuring children can enjoy gaming at their bedside. With grants ranging from $25,000 to $150,000, the program focuses on offering joy and distraction, helping young patients cope with their hospital stays while facilitating connections with peers.
Joy In Childhood Foundation Inc

US $33,000

Watson-Brown Foundation Grant

Full proposal due Apr 15, 2027
The Watson-Brown Foundation Grant supports organizations dedicated to preserving the history and culture of the South. It offers various types of grants, including for educational programming and historic preservation, with a focus on southern studies. Eligible recipients include public charities in the southeastern United States. The Foundation's Junior Board of Trustees also awards grants to preservation projects in east central Georgia, emphasizing youth engagement in cultural heritage.
Watson Brown Foundation Inc

Up to US $300,000

Live Like Bella Pediatric Cancer Research Initiative: New Investigator Research (NIR) Category

Pre proposal due Nov 30, 2026

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

The Live Like Bella Pediatric Cancer Research Initiative

The Florida Department of Health’s Live Like Bella Pediatric Cancer Research Initiative supports the pursuit of identifying cures for pediatric cancer.

The Live Like Bella Pediatric Cancer Research Initiative is established in section 381.922, Florida Statutes, works to advance progress toward curing pediatric cancer through grants awarded through a peer-reviewed, competitive process, to:

  • Significantly expand pediatric cancer research capacity in Florida
  • Improve both research and treatment through greater pediatric enrollment in clinical trials networks
  • Reduce the impact of pediatric cancer on disproportionately impacted individuals

Research Focus

Applications submitted in response to this Funding Opportunity Announcement (FOA) must be responsive to one of the following areas of focus. 

  • Prevention and Treatment
  • Screening
  • Obesity
  • Treatment-Related Morbidities
  • Technology Transfer Feasibility (TTF)
  • Investigational New Drug or Investigational Device Exemption

Efforts to foster collaborations among institutions, researchers, and community practitioners should be included, when possible. Preference will be given to applications that address at least one of the cancers listed in the Research Priorities section of this FOA.

Funding Information

Applicants must request funding in the preceding grant categories to pursue research in the areas of focus outlined in the Research Focus section of this FOA. Preference will be given to applications that address the priorities listed in the Research Priorities section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category (depending on the grant program) to pursue an area of focus from the Research Focus section of this FOA. Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding. 

The grant categories are: 1) Bridge; 2) Discovery Science; 3) Emerging Therapeutics and Technologies; 4) Equipment; 5) Multicenter Clinical Trials; 6) New Investigator Research (NIR); 7) High-Risk, High-Reward Clinical Research; 8) High-Risk, High-Reward Discovery Science; 9) Non-Typical Clinical Trials/Socio-Behavioral Research; 10) Research Infrastructure

Bella Initiative Grant Categories: New Investigator Research (NIR)

The intent of the NIR grant category is to foster development of new investigators so they may undertake independent research that is competitive for national research funding. New investigators must have been full-time faculty for no more than six years and must work under the mentorship of a senior investigator.

Maximum Duration: 36 months

Florida Department of Health

Up to US $125,000

Live Like Bella Pediatric Cancer Research Initiative: High-Risk, High-Reward Discovery Science Category

Pre proposal due Nov 30, 2026

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

The Live Like Bella Pediatric Cancer Research Initiative

The Florida Department of Health’s Live Like Bella Pediatric Cancer Research Initiative supports the pursuit of identifying cures for pediatric cancer.

The Live Like Bella Pediatric Cancer Research Initiative is established in section 381.922, Florida Statutes, works to advance progress toward curing pediatric cancer through grants awarded through a peer-reviewed, competitive process, to:

  • Significantly expand pediatric cancer research capacity in Florida
  • Improve both research and treatment through greater pediatric enrollment in clinical trials networks
  • Reduce the impact of pediatric cancer on disproportionately impacted individuals

Research Focus

Applications submitted in response to this Funding Opportunity Announcement (FOA) must be responsive to one of the following areas of focus. 

  • Prevention and Treatment
  • Screening
  • Obesity
  • Treatment-Related Morbidities
  • Technology Transfer Feasibility (TTF)
  • Investigational New Drug or Investigational Device Exemption

Efforts to foster collaborations among institutions, researchers, and community practitioners should be included, when possible. Preference will be given to applications that address at least one of the cancers listed in the Research Priorities section of this FOA.

Funding Information

Applicants must request funding in the preceding grant categories to pursue research in the areas of focus outlined in the Research Focus section of this FOA. Preference will be given to applications that address the priorities listed in the Research Priorities section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category (depending on the grant program) to pursue an area of focus from the Research Focus section of this FOA. Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding. 

The grant categories are: 1) Bridge; 2) Discovery Science; 3) Emerging Therapeutics and Technologies; 4) Equipment; 5) Multicenter Clinical Trials; 6) New Investigator Research (NIR); 7) High-Risk, High-Reward Clinical Research; 8) High-Risk, High-Reward Discovery Science; 9) Non-Typical Clinical Trials/Socio-Behavioral Research; 10) Research Infrastructure

Bella Initiative Grant Categories: High-Risk, High-Reward Discovery Science

Research in this mechanism of support pursues bold, unconventional hypotheses or cutting-edge methodologies to explore uncharted biological territories relevant to tobacco-related diseases and cancer. This research challenges existing paradigms, investigates counterintuitive phenomena, or develops innovative approaches that may appear technically unfeasible. The high-risk nature stems from possibilities that novel hypotheses prove incorrect or new methods fail to yield interpretable data. The high-reward potential includes groundbreaking discoveries that fundamentally alter disease understanding, identify new therapeutic targets, or elucidate previously unknown pathways spawning multiple research directions.

Maximum Duration: 36 months

Florida Department of Health

Up to US $900,000

Live Like Bella Pediatric Cancer Research Initiative: Multicenter Clinical Trials Category

Pre proposal due Nov 30, 2026

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

The Live Like Bella Pediatric Cancer Research Initiative

The Florida Department of Health’s Live Like Bella Pediatric Cancer Research Initiative supports the pursuit of identifying cures for pediatric cancer.

The Live Like Bella Pediatric Cancer Research Initiative is established in section 381.922, Florida Statutes, works to advance progress toward curing pediatric cancer through grants awarded through a peer-reviewed, competitive process, to:

  • Significantly expand pediatric cancer research capacity in Florida
  • Improve both research and treatment through greater pediatric enrollment in clinical trials networks
  • Reduce the impact of pediatric cancer on disproportionately impacted individuals

Research Focus

Applications submitted in response to this Funding Opportunity Announcement (FOA) must be responsive to one of the following areas of focus. 

  • Prevention and Treatment
  • Screening
  • Obesity
  • Treatment-Related Morbidities
  • Technology Transfer Feasibility (TTF)
  • Investigational New Drug or Investigational Device Exemption

Efforts to foster collaborations among institutions, researchers, and community practitioners should be included, when possible. Preference will be given to applications that address at least one of the cancers listed in the Research Priorities section of this FOA.

Funding Information

Applicants must request funding in the preceding grant categories to pursue research in the areas of focus outlined in the Research Focus section of this FOA. Preference will be given to applications that address the priorities listed in the Research Priorities section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category (depending on the grant program) to pursue an area of focus from the Research Focus section of this FOA. Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding. 

The grant categories are: 1) Bridge; 2) Discovery Science; 3) Emerging Therapeutics and Technologies; 4) Equipment; 5) Multicenter Clinical Trials; 6) New Investigator Research (NIR); 7) High-Risk, High-Reward Clinical Research; 8) High-Risk, High-Reward Discovery Science; 9) Non-Typical Clinical Trials/Socio-Behavioral Research; 10) Research Infrastructure

Bella Initiative Grant Categories: Multicenter Clinical Trials

Funding from this grant category for multicenter clinical trials is intended to support evaluation of the safety, efficacy, and effectiveness (Phase I, II, III, and IV) of repurposed or new and innovative drugs and other treatments for pediatric cancers. Trials may include randomized clinical trials or innovative applications of precision medicine strategies using targeted therapies. Multicenter clinical trials need to involve investigators from at least two distinct research/clinical facilities in Florida and must be implemented in two or more locations in Florida.

Maximum Duration: 48 months

Florida Department of Health

US $10,000 - US $30,000

Coastal Partnership Initiative Grant Program

Applications due Oct 31, 2026
The Coastal Partnership Initiative Grant Program provides competitive funding from the NOAA to support Florida's coastal counties and municipalities in managing coastal resources effectively. Eligible applicants include local governments, public colleges, and nonprofits, focusing on climate resilience, resource stewardship, public access, and waterfront revitalization. The program aims to enhance community preparedness against natural hazards, promote environmental awareness, and improve coastal infrastructure, ensuring sustainable development and protection of Florida's unique coastal ecosystems.
Florida Department of Environmental Protection

Up to US $12,902,972

State Assistance for Fentanyl Eradication (S.A.F.E.)

Rolling deadline

Florida Department of Law Enforcement

FDLE is composed of five areas: Executive Direction and Business Support, Criminal Investigations and Forensic Science, Criminal Justice Information, Criminal Justice Professionalism and Florida Capitol Police. In addition, the department formally coordinates boards, councils, and commissions. FDLE’s duties, responsibilities and procedures are mandated through Chapter 943, FS, and Chapter 11, FAC. 

Our Mission: To promote public safety and strengthen domestic security.

State Assistance for Fentanyl Eradication (S.A.F.E.)

State funding is available to conduct investigations designed to combat illegal fentanyl activity. This grant provides reimbursement for approved fentanyl-related investigative operations, which may include:

  • Overtime
  • Relevant Travel Costs
  • Purchase of Investigative Supplies
  • Equipment Purchases
  • Relevant Contractual Services
  • Training Costs
  • Other Costs Associated with Cases Focusing on Fentanyl Eradication

Awards

Available funds will be distributed based on the operational needs of each agency’s investigations as approved by the S.A.F.E. Executive Board, not to exceed a combined total of $12,902,972.

Florida Department of Law Enforcement

US $1,000 - US $75,000

Fish & Wildlife Foundation of Florida: Wildlife Foundation of Florida

Applications due Jul 1, 2027
The Fish & Wildlife Foundation of Florida supports conservation and sustainable enjoyment of Florida's lands and wildlife. With over $66 million awarded since 1994, the Foundation focuses on public hunting, safety programs, and shooting sports. Grants range from $1,000 to $75,000, with a preference for matching funds. Eligible applicants include government agencies, educational institutions, and non-profits. The Foundation may also consider for-profit proposals at its discretion.
Fish & Wildlife Foundation Of Florida Inc

Up to US $300,000

Florida Boating Infrastructure Grant Program (BIGP): Tier I

Applications due Jul 1, 2027

Florida Constitution authorizes the Fish and Wildlife Conservation Commission

The Florida Constitution authorizes the Fish and Wildlife Conservation Commission to enact rules and regulations regarding the state's fish and wildlife resources. To do this, the 7 FWC Commissioners meet 4 times each year to hear staff reports, consider rule proposals and conduct other Commission business.

Boating Infrastructure Grant Program (BIGP)

The Boating Infrastructure Grant Program (BIGP) provides funding through competitive grants for tie-up facilities for transient recreational boats 26 feet or longer (non-trailerable). This program is funded by the U.S. Fish and Wildlife Service. 

Types of Funding Available

There are two types of grants, Tier I and Tier II

Tier I Projects

In any given funding cycle, the State of Florida may receive a total of $300,000 for Tier I projects. All Tier I projects must meet the eligibility requirements of 50 CFR 86.20. Each Tier I project cannot exceed $300,000; however, the State of Florida may select one (1) or as many Tier I projects as are eligible so long as the aggregate of these projects does not total more than that year's funding cycle allotment. Tier One projects compete against other Florida projects for funding.

Florida Fish and Wildlife Conservation Commission

Up to US $500,000

Cultural Facilities Grant

Applications due Jul 10, 2027
The Cultural Facilities Grant supports organizations focused on cultural programming through funding for renovation, construction, or acquisition of cultural facilities. Eligible applicants must conduct arts and cultural programming at least 85% of the time, meet legal status requirements, and have matching funds documented. The program excludes funding for projects such as parking facilities and commercial endeavors. This grant aims to enhance the cultural landscape in Florida by ensuring facilities are accessible and adequately funded for community engagement.
Florida Department of State: Arts and Culture

US $125,000 - US $175,000

Arbor Rising Grant

Letter of inquiry due Jun 9, 2027
Arbor Rising Grant, established in 2010, is a NYC-based nonprofit providing unrestricted multi-year funding and capacity-building support to nonprofits focused on alleviating poverty. The grant process occurs every three years, with the next round in 2025 being invitation-only. Eligible organizations must demonstrate high potential and effective leadership, typically operating on a modest budget. Arbor Rising prioritizes applicants from the NYC metro area while expanding to cover the lower 48 US states.
Arbor Brothers Inc

US $9,000,000 - US $14,000,000

Florida Boating Infrastructure Grant Program (BIGP): Tier II

Applications due Jul 1, 2027
The Florida Boating Infrastructure Grant Program (BIGP) Tier II offers competitive funding for transient recreational boat tie-up facilities. With an annual budget between $9 million and $14 million, it supports projects exceeding 26 feet in length. While there is no maximum project cost, federal funding is capped at $1.5 million. This program, overseen by the Florida Fish and Wildlife Conservation Commission, encourages innovative proposals that meet stringent eligibility criteria.
Florida Fish and Wildlife Conservation Commission

Up to US $5,000,000

Pathways to Career Opportunities – Grow Your Own Teacher Apprenticeship Program

Applications due Apr 27, 2027

 Florida Department of Education

The Department of Education serves as the single repository of education data from school districts, state and community colleges, universities, and independent postsecondary institutions - allowing us to track student performance over time and across varying education sectors.

We administer a statewide reading initiative for Florida's public schools, and among community groups and volunteer organizations that support them, with a goal of having every child able to read at or above grade level.

Pathways to Career Opportunities – Grow Your Own Teacher Apprenticeship Program

The state funds appropriated in House Bill 5001, General Appropriations Act (GAA) (Item Number 121 – Aid to Local Governments – Grant Aids), includes a $5 million set aside for the Grow Your Own Teacher Apprenticeship Program.

The purpose of this sub-initiative is to increase the supply of qualified teachers by creating a teacher pipeline for Florida. It is designed to encourage partnerships between eligible applicants and participating employers (Florida school districts, charter schools and charter management organizations) to provide an innovative, no-cost pathway to the teaching profession for registered teacher apprentices.

The funds for this grant are appropriated in the 2026 General Appropriations Act (GAA) as a sub initiative to the Pathways to Career Opportunities Grant (PCOG).

Florida Department of Education

US $2,500 - US $50,000

Urban and Community Forestry - Inflation Reduction Act Grant

Applications due Nov 17, 2026
The Urban and Community Forestry - Inflation Reduction Act Grant aims to enhance urban forest management in Florida, promoting the retention and expansion of community tree canopies. This initiative emphasizes the importance of trees in urban settings, highlighting their benefits such as increased property values, improved mental and physical health, and reduced environmental issues. By educating communities on proper tree care and green infrastructure, the program strives to optimize the ecological and social advantages of urban forestry.
Florida Department of Agriculture and Consumer Services

US $1,005,287 - US $79,657,340

Head Start/Early Head Grants in Multiple States

Applications due Dec 16, 2026
The US Department of Health & Human Services announces a competitive funding opportunity for the Head Start/Early Head Start programs across various states. This initiative aims to enhance services for low-income families and children, promoting their social and economic well-being. With approximately $818.3 million available, the program seeks to expand access to quality early childhood education, thereby strengthening community stability and prosperity. Interested applicants can seek further information through the OHS Operations Center.
US Dept. of Health & Human Services: Administration for Children & Families

Up to US $350,000

Ed and Ethel Moore Alzheimer's Disease Research Program: Multi-Vitamin - Standard Grant

Full proposal due Nov 20, 2026

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

Ed and Ethel Moore Alzheimer's Disease Research Program: Multi-Vitamin

Research Focus

The purpose of this announcement is to stimulate research activities that study the impact of daily vitamin use on the improvement of cognitive function and any associated health care cost impacts on populations over the age of 65.

Funding Information

Applicants must request funding in the following grant categories to pursue research in the area of focus outlined in the Research Focus section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category to pursue the area of focus from the Research Focus section of this FOA.   

The grant categories are: 1) Consortium Grant; 2) Standard Grant; 3) Pilot Grant; 4) Postdoctoral Research Fellowship Grant

Grant Categories: Standard Grant

Research projects that are fully developed, scientifically rigorous, and include sound background information, hypotheses, and promising preliminary results or supporting data. Organizations choosing to submit more than one Standard Grant application may have no more than three applications.

Florida Department of Health

Up to US $100,000

Ed and Ethel Moore Alzheimer's Disease Research Program: Multi-Vitamin - Pilot Grant

Full proposal due Nov 20, 2026

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

Ed and Ethel Moore Alzheimer's Disease Research Program: Multi-Vitamin

Research Focus

The purpose of this announcement is to stimulate research activities that study the impact of daily vitamin use on the improvement of cognitive function and any associated health care cost impacts on populations over the age of 65.

Funding Information

Applicants must request funding in the following grant categories to pursue research in the area of focus outlined in the Research Focus section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category to pursue the area of focus from the Research Focus section of this FOA.   

The grant categories are: 1) Consortium Grant; 2) Standard Grant; 3) Pilot Grant; 4) Postdoctoral Research Fellowship Grant

Grant Categories: Pilot Grant

Exploratory, novel studies that break new ground or extend previous discoveries toward new directions or applications. No preliminary data are required but may be included if available. Research organizations are eligible to apply for no more than two Pilot Grants that address the Priority Area listed.

Florida Department of Health

US $75,000

Coastal Resilience Program RFP

Letter of inquiry due Mar 1, 2027
The National Sea Grant Law Center is inviting proposals for the Coastal Resilience Program to research laws and policies addressing coastal resilience challenges such as sea level rise and flooding. With a funding cap of $150,000 over two years, this initiative aims to assess the effectiveness of existing policies and promote informed decision-making in coastal management. Up to two projects will be selected for funding, supporting innovative solutions to enhance community resilience against environmental threats.
National Sea Grant Law Center

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Operating Grants for Nonprofits in Florida Highlights

Looking for operating grants for nonprofits in Florida?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in Florida recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in Florida

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ Operating grants for nonprofits in Florida grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

64 Operating grants for nonprofits in Florida over $25K in average grant size

49 Operating grants for nonprofits in Florida over $50K in average grant size

41 Operating grants for nonprofits in Florida supporting general operating expenses

200+ Operating grants for nonprofits in Florida supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Health & Medicine

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Florida?

Most grants are due in the first quarter.

Q1
27.5%
Q2
26.3%
Q3
23.2%
Q4
23.0%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Florida?

Grants are most commonly $12,500.

$100 $100 Min.
$12,500 $12.5 K Median
$487,658 $487.7 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Florida?

Grants are most commonly $127,766.

$127,766

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Florida year over year?

In 2024, funders in Florida awarded a total of 120,990 grants.

2022 107,491

2023 109,840

2024 120,990

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Florida given out in Florida, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Florida changing over time?

Funding has increased by 4.30%.

2022 $14,150,322,449

2023 $14,761,745,220
4.32%

2024 $15,396,491,509
4.30%

Florida Counties That Receive the Most Funding

How does grant funding vary by county?

Miami Dade County, Orange County, and Hillsborough County receive the most funding.

County Total Grant Funding in 2024
Miami Dade County $5,036,107,623
Orange County $3,251,041,805
Hillsborough County $2,859,448,977
Broward County $2,438,211,409
Palm Beach County $2,225,921,170

Related Grants in Florida

Browse Other Nonprofit Operations & Capacity Grants in Florida

Browse Grants For Nearby Locations

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