Best Small Grants for Nonprofits in Florida

The CFF/NIH R01-Unfunded Award, offered by the Cystic Fibrosis Foundation, supports exceptional CF-related research projects that have been submitted to NIH but lack funding. This program aims to bridge the gap for meritorious projects, providing up to $125,000 per year for two years. By facilitating research in cystic fibrosis, the foundation helps ensure that innovative ideas can continue to progress toward improving care and outcomes for individuals affected by this disease.

The ASF Family Fund Grant, offered by the Angelman Syndrome Foundation, provides crucial financial assistance to families of individuals with Angelman syndrome. This rare neuro-genetic disorder affects approximately 500,000 people globally. The fund aims to enhance the quality of life for affected individuals, allowing caregivers to apply for up to $5,000 to cover essential needs. Limitations include restrictions on certain expenses and prior grant awards. This initiative aims to support families through education and necessary resources.

The Richard I. Stessel Waste Management Award, presented annually by the Air & Waste Management Association, honors outstanding achievements in waste management. This prestigious award acknowledges individuals and organizations for their significant contributions to the science and practice of waste management, including technological advancements, waste regulation, and educational excellence. Named after Professor Richard I. Stessel, the award promotes innovative solutions for environmental sustainability, encouraging professionals to serve as role models in the field.

The Pathway to Stop Diabetes Accelerator Award supports innovative early-career researchers tackling diabetes-related challenges. It offers flexible funding up to $325,000 annually for transformative research. Candidates must have independent faculty status and demonstrated productivity in diabetes research. The program aims to inspire groundbreaking discoveries by providing essential resources and mentorship, thereby improving the lives of those affected by diabetes. Nominations focus on translational research that bridges basic science with practical benefits for patients.

The AWS Welding Workforce Grants aim to enhance welding programs by providing up to $50,000 for essential resources such as new equipment and training. This initiative addresses the growing demand for skilled welders while supporting educational institutions. Eligible applicants include secondary schools, community colleges, and post-secondary programs. Preference is given to proposals that significantly increase welding graduates and address geographic areas with high needs. Note: Applications are currently closed and will reopen in January 2026.

The AE Foundation Community Grants aim to support US and Canadian non-profit organizations focused on enhancing the mental health and well-being of young people. By funding local programs, the AE Foundation empowers teens and young adults to embrace authenticity and build a brighter future. Eligible organizations must be certified 501(c)3 non-profits or registered charities, and grant funding should be utilized within 365 days of receipt. This initiative reinforces the importance of mental health in today's society.

The 1Fur1 Foundation Grant supports U.S.-based 501(c)(3) charities that engage in animal-assisted programs. Eligible organizations can apply for grants ranging from $500 to $7,500 to support Animal Assisted Therapy, Activity, and Service Dog programs. The foundation focuses on charities that align with its mission and does not fund individual requests, for-profit businesses, or initiatives that promote animal cruelty. Applications are reviewed within 90 days.

American Psychiatric Association Foundation

There is no health without mental health. The APA Foundation is working in your community to provide the support and resources we all need to prioritize mental wellbeing where you live, learn, work, worship, and play.

Backed by the medical expertise of the APA and industry-leading strategic partners, we administer community-changing programs, public education campaigns, grants, and awards aimed at increasing mental health literacy, connecting individuals to needed care, and shifting attitudes toward mental health.

Our Mission is to promote the mental health and well-being of individuals and communities. Our Vision is a mentally healthy nation for all – where we live, learn, work, worship, and play.

Diversity Leadership Fellowship

The Diversity Leadership Fellowship identifies and motivates minority psychiatry residents or those interested in minority and vulnerable populations to become well equipped to teach, administer, and provide culturally competent, evidence based mental health and substance abuse services to diverse minority groups and at-risk populations. These populations include—but are not limited to—American Indians/Native Alaskans, Asian Americans/Native Hawaiians/Native Pacific Islanders, Blacks/African Americans, Hispanics/Latinos, LGBTQ, and religious minorities. Program Benefits:

• Sponsorship to attend a minimum of four APA meetings:
  • Two APA Annual Meetings
  • Two Fellowship Forums
• Develop leadership skills in the field of psychiatry and advance understanding of the life experiences of racial ethnic minority communities
• Gain an understanding of APA/APAF Governance through observation and service on an APA Council, Committee, or APAF initiative
• Have the opportunity to sit on the APAF Board of Directors as a non-voting member (one Diversity Leadership fellow allowed)
• Cultivate a professional network with psychiatrists interested in minority mental health and services through exclusive events and engagements with APA leaders. Establish relationships and peer-mentorship with a diverse group of resident fellows with similar career interests and goals

The Christina Sue Lilja Resource Grants support agricultural literacy by providing funds for educators to purchase resources from the Ag Foundation store. In 2025, 100 educators will receive $100 in store credits, selected randomly if applications exceed this number. This initiative, backed by the CSL Foundation, honors Christy Lilja's legacy of advocating for agricultural education. The grants aim to enhance classroom resources and improve students' understanding of agriculture, ensuring access to accurate information.

The Anna Fuller Fund Grant provides year-round support for organizations dedicated to alleviating suffering caused by cancer. Established in memory of Egbert C. Fuller’s wife, the fund prioritizes applications that focus on cancer research and education initiatives. Eligible applicants must be 501(c)(3) organizations or equivalent charities outside the U.S. Grant funds cannot be used for direct treatment, ensuring that resources are allocated to research and public education.

The Ryder Sroufe Memorial Scholarship, established by the Community Foundation of Whitley County in 2025, honors the legacy of Ryder Carl Sroufe. This scholarship supports young individuals who embody enthusiasm, humility, and compassion, reflecting Ryder's spirit of kindness and service. It aims to empower the next generation of leaders and helpers, ensuring that Ryder's values of hard work and community commitment continue to thrive. Eligible students are recognized for their efforts to strengthen their communities.

The Frederic C. Collin Trust Grant supports 501(c)(3) organizations in promoting polo and tennis, especially among youth. Established under Frederic C. Collin's will, it offers grants ranging from $2,000 to $3,800, with an annual total giving of approximately $9,000. Applications are accepted year-round for consideration during the annual grant meeting. This initiative aims to enhance participation in these sports, fostering talent and interest among young players.

The Society of Family Planning is offering the Bridging Investments in Abortion and Contraception Research Grant to support the completion of NIH grants focused on abortion and contraception. This funding aims to mitigate the impact of recent funding terminations by ensuring that vital research continues, promoting equitable access to reproductive health. Proposals can request up to $100,000 and must detail their alignment with the Society's mission, planned activities, and budget within a 24-month timeline.

North Central Zone Covering Jefferson and Lewis Counties "Retired Educators Helping Future Educators" In Partnership with The Northern New York Community Foundation

Scholarship Awards for 2026

Three $1,000.00 scholarships will be awarded by the North Central Zone of the Retired Educators of New York (RENY) and the Northern New York Community Foundation (NNYCF) for students residing in Jefferson and/or Lewis Counties - These are a onetime award to help students get started with their college education

Any high school senior pursuing a career in the teaching profession is eligible

• You must be a 2025-2026 high school senior
• You must be accepted into a college program starting in the Fall of 2026

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is announcing a Notice of Funding Opportunity (NOFO) for Diabetes Research Centers (DRCs). These centers aim to foster collaboration among diabetes researchers, enhance preclinical and clinical research, and provide access to specialized resources. Emphasis is on innovative scientific themes and collaborative projects in areas such as Immunology and Artificial Intelligence. Although applications are not currently solicited, potential applicants are encouraged to prepare for future submissions.

The Bowman Family Swimming Scholarship, provided by the Central Kentucky Community Foundation, aims to support graduating high school seniors in Hardin County who are active swimmers. Eligible applicants must have a minimum cumulative GPA of 3.0 and be involved with their school's swim team. This scholarship embodies the Foundation's mission to enhance community life by empowering students to pursue their educational goals in athletics.

The Civic Engagement Microgrant Grant Program, funded by Research!America, aims to enhance public engagement skills among early-career scientists. By providing financial support for innovative projects, this initiative encourages collaborations across various STEM disciplines. Grantees will develop essential skills in communication and policy-making to strengthen community ties and promote science as a national priority. This program addresses the critical need for scientists to connect with local communities and policymakers to ensure the relevance and impact of scientific research.

The Trails Capacity Program, previously known as the Trail Fund Grant, aims to enhance community capacity for trail maintenance, research, and stewardship training across the nation. The program focuses on supporting non-Forest Service Federal lands, as well as state and local areas, fostering inclusivity and improved user behavior. By collaborating with diverse trail partners, it seeks to ensure effective stewardship and sustainable trail management, ultimately promoting public access and enjoyment of America's natural landscapes.

Access Advocate for Clinical Research Participation

Objective:

This program will support implementation and evaluation of a Parkinson’s disease (PD) focused Access Advocate model designed to increase inclusive research participation. Funding will support Access Advocates at clinical sites to build practical, relationship based pathways to improving representative research enrollment and retention.

Funding Details:

• Duration: 24 months 
• Award Amount: $200,000 

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and its inclusive recruitment strategy has examined what barriers and motivators shape participation (e.g., FIRE-UP PD study3) as well as funded sites to pilot tactics that address those barriers (e.g., Black & African American Connections to Parkinson’s Disease study4). Now we aim to scale and validate approaches that show early promise by investing more deeply and measuring impact across settings.

This program will fund advocates at clinical sites to build practical, relationship-based pathways to improving representative research enrollment and retention. These support staff will help patients and care partners navigate health system complexity and everyday needs that often determine whether research participation is feasible. They will help address barriers such as transportation, caregiving responsibilities, language needs, and insurance and financial strains by connecting people to resources, coordinating logistics and providing consistent follow-up. These advocates also should discuss research participation opportunities with patients and connect them to recruiting studies.

The model is grounded in the idea that research participation is more feasible when (i) foundational practical needs are addressed first and (ii) raised by a trusted health care partner. By helping to reduce practical barriers, advocates are expected to increase screenings, enrollment conversion and retention across key trial milestones.

This program will test these hypotheses and further establish training, infrastructure needs and sustainability of such positions.

Program Goal

This program aims to:

• Support establishment of site-based Access Advocates to support potential participants and care partners across multiple active or planned PD studies.
• Evaluate needs and opportunities for onboarding and ongoing training for advocates in PD and clinical research fundamentals as well as site and local resources.
• Recommend repeatable workflows for identifying prospective participants, assessing barriers, connecting them to resources, coordinating logistics and supporting follow-up.
• Collect and report a core set of evaluation metrics across sites (reach, encounters, referrals, screened, enrolled, retained), including barrier tracking and resolution.
• Evaluate the impact of Access Advocates in recruiting and retaining underrepresented community individuals to/in Parkinson’s studies.
• Evaluate the impact of Access Advocates on “health system value” indicators (e.g., appointment adherence/show rates, medication access/adherence proxies) that could support funding sustainability from other sources.
• Establish a cross-site learning community that enables funded sites to share lessons, refine the Access Advocate model and inform broader adoption beyond the funding period.

The Emergency Department Alternatives to Opioids Program aims to implement practices that offer alternatives to opioid treatments in hospitals. This initiative focuses on reducing the harmful consequences of opioid use for pain management, promoting safer treatment options, and minimizing the risk of opioid misuse and overdose. Specifically, it targets healthcare organizations to enhance their pain care strategies, ultimately contributing to better patient safety and health outcomes.

The Kidney Precision Medicine Project Central Hub, funded by the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), aims to enhance our understanding of Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). This initiative, which began in FY2017, focuses on ethically collecting and analyzing kidney biopsy tissues to uncover molecular pathways. The project was expanded in FY2022 to improve participant recruitment and tissue analysis, driving forward research in kidney health.

The Pathway to Stop Diabetes Initiator Award (INI) aims to support early career researchers in diabetes research by providing funding and mentorship. With a focus on innovative and transformational ideas, this initiative encourages researchers to develop groundbreaking solutions for diabetes prevention and management. The award offers up to $100,000 annually in Phase 1 and $325,000 in Phase 2, fostering a new generation of leaders committed to improving the lives of those affected by diabetes.

The Gary Paul Piantanida Scholarship, established by Paul and Edna Piantanida in memory of their son Gary, offers financial support to high school seniors, undergraduates, and returning students in San Luis Obispo County. This scholarship honors students who exemplify strong work ethic, dependability, and integrity, reflecting the values cherished by the Piantanidas. With a commitment to fostering educational opportunities, the Community Foundation San Luis Obispo County encourages applicants to pursue their dreams and contribute positively to their communities.

The McKnight Clinical Translational Research Scholarship supports young investigators focusing on cognitive aging and age-related memory loss. Funded by the McKnight Brain Research Foundation, this scholarship offers $65,000 annually for two years, plus an education stipend. Eligible applicants should have completed their PhD or residency within the last five years and conduct their research in accredited U.S. institutions. The award emphasizes rigorous training and aims to foster careers in human cognitive aging research.

The Alzheimer’s Foundation of America Bi-Annual Grant aims to support nonprofit organizations in their efforts to enhance the lives of individuals impacted by Alzheimer’s disease and related dementias. Each grant, valued at $6,000, is awarded twice a year, focusing on innovative programs and services. AFA emphasizes partnership and collaboration, enabling grantees to manage their own policies and programs while adhering to specific funding guidelines. This initiative underscores AFA's commitment to compassionate care and ethical standards.

The RFA: Biology to Prevention Award (CRUK) aims to foster innovative translational research that enhances understanding of cancer biology, ultimately leading to effective prevention strategies. Joint applications from UK and US research teams are encouraged, with a focus on equal partnerships and complementary expertise. The funding provides up to £600,000 for UK costs and up to $946,000 for US costs, supporting projects of 1 to 5 years duration that address critical research questions in cancer prevention.

The Brees Dream Foundation Grant aims to enhance the lives of cancer patients while providing essential care, education, and opportunities for children and families in need. With the support of generous donors and partners, the Foundation is dedicated to advancing cancer research and offering vital resources to those facing challenges. This commitment reflects a profound dedication to improving quality of life and fostering hope in communities.