Best Grants for 501(c)(3)

The PDCED Appalachian Regional Commission Grant supports economic development in Pennsylvania's Appalachian Region. It funds projects that enhance job creation, improve infrastructure, and promote business development. The goal is to leverage federal, state, and local resources to strengthen the economy of this 205,000-square-mile area. Funding is prioritized for initiatives that lead to sustainable economic growth, workforce readiness, and improved community capacity. Eligible projects include technical assistance, infrastructure development, and local government support.

The Skillman Foundation Grant Partners program aims to empower Detroit youth through strategic partnerships that transform education systems. While they typically invite applications proactively, they remain open to connecting with organizations that support young people in Detroit. Eligible partners include nonprofit organizations and public agencies, with a focus on those offering inclusive opportunities for all youth. The foundation emphasizes advocacy for policy changes that benefit children in the community.

The Bargain Box of Hilton Head Grant, established in 1965, supports Beaufort County non-profits with cash grants derived from store sales. Operating as a 501(c)(3), it has contributed over $15.3 million to local charities, aiding in community activities related to education, health, and safety. Organizations must meet eligibility criteria, including having an active Board of Directors and a community focus. The grant fosters local engagement and supports a diverse array of charitable efforts.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

HIV, AIDS, and prevention

Help with healthcare costs for HIV, AIDS, and prevention

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

HIV, also known as human immunodeficiency virus or acquired immunodeficiency syndrome, is a virus that attacks the immune system. When left untreated, it can develop into AIDS. HIV is a chronic disease that affects the immune system.

The Vermont Housing and Conservation Board offers Organizational Development Grants to support nonprofit organizations in developing affordable housing and conservation projects. Eligible applicants, including municipalities and certain state agencies, can receive up to $33,750, while new organizations may apply for up to $12,000. These grants aim to ensure long-term benefits for Vermonters and promote sustainable community development. For application inquiries, please contact the Conservation Director.

The Gordon Foundation for Children and Youth offers the Special Projects Grant Program to support initiatives that enhance the mental health and well-being of children and youth. This program funds a variety of projects, including sensory rooms for children with special needs, newsletters for youth in care, and educational trips for urban students to rural communities. Eligible applicants include individuals, schools, and organizations dedicated to improving youth mental health.

The Janet Y. Sato Na Lima Paheona Scholarship Fund supports Maui high school graduates pursuing a Bachelor of Arts degree. To qualify, applicants must demonstrate financial need, be Hawaii residents with a minimum GPA of 2.7, and provide a letter of recommendation. This fund aims to empower local students in various artistic fields, including music, dance, and graphic design, fostering creativity and educational growth within the community.

The PCCF: Women’s Giving Fund Grant supports transformative philanthropy for women and children in Summit County, Utah. Funded by the Park City Community Foundation, this grant seeks high impact projects that yield measurable outcomes and foster community collaboration. Eligible applicants must be 501(c)(3) nonprofit organizations that demonstrate a commitment to diversity, equity, and inclusion, while presenting attainable goals and measurable objectives. This initiative aims to create lasting positive change within the community.

Grantmaking

Funding Rooted in Relationships

Our grantmaking supports the work that helps people, families, and neighborhoods build healthy, equitable communities, across generations. It is strategic, relationship-centered, grounded in trust, and shaped by ongoing learning with our community partners.

We focus on work that addresses root causes, strengthens community-led solutions, and builds long-term capacity in Kalamazoo County.

Strategic Pillars

Our strategic pillars are based on what we’ve learned from community, nonprofit and elected leaders. We all share the vision for a Kalamazoo County that includes:

The Baldwin Hills Conservancy is inviting applications for the year-round Proposition 84 Grant Program, aimed at projects that enhance water quality in the Ballona Creek Watershed and improve access to Baldwin Hills Parklands. With $10 million allocated for such initiatives, eligible applicants include public entities and non-profits. Priority will be given to projects demonstrating urgency, innovation, and community involvement, fostering both environmental protection and public enjoyment of coastal resources.

Humboldt Health Foundation

The mission of Humboldt Health Foundation (formerly the Union Labor Health Foundation), a supporting organization of HAF+WRCF, is to improve the health and well-being of the residents and communities of Humboldt County.

Grants

We’re Here to Support You

HAF+WRCF grant funding supports charitable programs and projects in our region (Humboldt, Del Norte, and Trinity counties in California, and Curry County, Oregon). 

Angel Fund

Grant Details

The Angel Fund provides small grants to support the unmet health needs of Humboldt County residents. Grants are made on a one-time basis, per person, per 365-day period. Items that are of a recurrent nature are generally not funded.

Average grants range in size from $50 – $250 (grants in excess of $500 are seldom approved). Decisions to grant funds are contingent upon funding criteria and the availability of funds at the time of review. 

There is a two-week turnaround processing time required for application review and check processing. The committee meets every Tuesday, with the exception of holidays. Occasionally the committee will ask for additional information before making a decision. This will often result in a longer turn-around time.

The Comcast NBCUniversal Foundation offers Local Impact Grants to nonprofit organizations in 11 markets, providing $225,000 to support local programs addressing community issues. Eligible organizations must be 501(c)(3) nonprofits with a revenue exceeding $100,000 and must operate in one of the specified television markets. The grants aim to empower youth through education, promote diverse storytelling, and enhance community engagement. This initiative underscores Comcast's commitment to fostering inclusion and equitable opportunities for underserved communities.

The Washington Coast Restoration and Resiliency Initiative provides critical funding and technical assistance to coastal communities in Washington State, addressing urgent ecological restoration needs while also creating jobs. Established by the Legislature in 2015, this program aims to enhance the health of the land and water, supporting both local economies and the environment. Projects funded must prioritize ecological protection and restoration, ensuring sustainable benefits for future generations.

The NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01) invites applications for innovative, hypothesis-driven clinical trials targeting diseases relevant to NIDDK's mission. With deadlines spanning from February 2025 to October 2026, this funding opportunity emphasizes collaboration across multiple centers to enhance clinical practices and public health outcomes. Interested applicants are encouraged to consult with NIDDK staff before submission to ensure alignment with program objectives.

The Adolph Coors Foundation's Youth and Adult Grant Programs support initiatives that promote self-reliance and integrity among Coloradans. Priorities include mentoring for youth, vocational training for adults, and fostering entrepreneurship. Organizations must be 501(c)(3) entities operating in Colorado, while special consideration is given to rural nonprofits. The Foundation aims for evidence-based results and transformational outcomes, focusing on programs that empower communities and enhance economic opportunities.

The Women's Fund of Southwest Iowa, established by the Community Foundation for Western Iowa, aims to empower women and families in the region. Through strategic partnerships and community insights, the fund supports initiatives that enhance women's self-sufficiency, health, and engagement. Eligible projects must serve primarily women and align with focus areas like health, education, and childcare. This grant provides critical support for programs fostering positive change in southwest Iowa communities.

The Allianz Life Insurance Company of North America offers the Financial Sustainability Grant to support nonprofit organizations that promote economic inclusion and financial stability. Grants range from $50,000 to $75,000 for one-year commitments, focusing on workforce success through education, job training, and entrepreneurial support. Eligible organizations must be tax-exempt under IRS 501(c)(3) and primarily serve low- to moderate-income families in the Twin Cities metro area.

The NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01) aims to support clinical trials that evaluate interventions for communication disorders. This funding opportunity encourages collaboration between NIDCD Project Scientists and investigators, focusing on trials that require FDA oversight, establish efficacy, or pose risks of harm. By fostering well-designed studies, the NIDCD seeks to advance treatment and prevention strategies in the field of communication disorders.

The BH UWC Consolidated Grant Program aims to enhance environmental equity by funding high-impact projects that address climate resilience and improve access to recreational spaces for disadvantaged communities. It aligns with the Cutting Green Tape initiative, focusing on strategic investments in conservation and community access. The program prioritizes projects that directly benefit vulnerable populations, ensuring equitable distribution of resources and measurable community benefits, thereby fostering sustainable development throughout California.

The Fund for Change Grants support organizations advocating for social change, focusing on underserved communities. With an average grant size of $10,000-25,000, it funds initiatives in housing, behavioral health, criminal justice reform, and environmental justice. Eligible organizations can apply annually, but multi-year commitments are not available. The fund does not support capital campaigns, indirect costs, endowments, or individual scholarships, ensuring that funds are directed towards direct program expenses.

The High-Need Healthcare Career Scholarship Program, offered by the District of Columbia Department of Health, aims to support local residents pursuing careers in high-demand healthcare roles. This initiative addresses critical workforce shortages for positions such as Home Health Aides, Certified Nurse Aides, and Emergency Medical Technicians. Funding is available for training programs that prepare individuals to meet these urgent healthcare needs, enhancing community health services.

The William T. Grant Scholars Program provides crucial support for early-career researchers aiming to expand their expertise through innovative research and mentoring. This five-year program focuses on reducing inequality and improving the use of research evidence to benefit young people in the U.S. By emphasizing the development of new disciplines and methods, the program encourages applicants to take bold risks in their research trajectories, ultimately fostering a supportive academic community.

The Arts Projects – Organisations Grants program, funded by the Australia Council for the Arts, supports diverse activities that enhance the arts sector and engage communities. With grants ranging from $20,000 to $100,000, eligible organizations can propose various initiatives including professional development, creative collaborations, and community engagement projects. Applications are open to organizations that benefit practicing Australian artists and audiences, fostering artistic innovation and cultural exchange.

The Helpful Harvest Grant, offered by the Community Foundation of Herkimer and Oneida Counties, aims to combat food insecurity in the region, especially during the winter and holiday seasons. This grant prioritizes food pantries, soup kitchens, and shelters, providing funding for food products, care packages, and necessary equipment like refrigeration. By supporting these crucial organizations, the grant helps ensure that local residents have access to essential food resources, fostering community resilience and collaboration.

As a 501(c)3 nonprofit organization, our main goals are:

• Bear conservation: Our goal is to conserve all 8 species through diminishing negative interactions via educating the public, providing co-existence strategies, volunteering, partnering with organizations for rehabilitation efforts and giving these animals a voice.
• Habitat preservation: As our organization grows, we will have dedicated spaces of land for these creatures to roam unharmed along with the other animals that live there. As the family grows, so do the Bear Grounds.
• Promoting “bear-awareness”: Bears may look cute – but it is important to practice protocols to ensure the safety of everyone.
• Education: From children to the elderly, we make it our goal to teach everyone about these animals, the roles they play and the importance of bears. We published a children’s book for the kids to learn about bears in a fun and interactive way.

Spectacled Bear Grant

Bear Grounds Coffee Co. is providing its first award toward bear conservation with the Spectacled Bear Grant in 2026. This funding is for research, rehabilitation, spectacled bear or territory conservation efforts only. One applicant will receive $200 to support their project.

Eligible projects include, but are not limited to:

• Scientific research and field studies.
• Wildlife rehabilitation and rescue programs.
• Habitat protection and restoration.
• Community-based conservation initiatives.
• Anti-poaching and human–bear conflict mitigation efforts.
• Sustainable coexistence programs.

The Central Minnesota "Difference Maker" Grants aim to foster significant advancements in racial equity across the region. Funded by the Central Minnesota Community Foundation, these grants, ranging from $10,000 to $30,000, support eligible nonprofits, schools, and government entities serving Benton, Stearns, and Sherburne Counties. The initiative encourages collaborative projects addressing racial disparities and community engagement, promoting sustainable impacts and additional investments.

The NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) support small businesses in conducting clinical trials for NIH-funded projects. This initiative aims to facilitate commercialization through partnerships with third-party investors while requiring a detailed Commercialization Plan. Applications are due by 5:00 PM local time, with Letters of Intent encouraged 30 days prior to the proposal deadline. The focus is on products aligned with the NINDS mission, including drugs, devices, and therapies.