Best Guam Grants for Nonprofits

The Pathways to Enable Secure Open-Source Ecosystems (PESOSE) program, funded by the National Science Foundation, aims to transform open-source research into sustainable ecosystems that tackle national and societal challenges. This initiative promotes innovation across various sectors, including AI and cybersecurity, by fostering strong governance and broad user engagement. PESOSE invites proposals to establish and enhance open-source ecosystems, ensuring their safety, security, and effectiveness in meeting emergent needs.

The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.

The ROSS Rapid Response Program (RRP) by the U.S. Department of Housing and Urban Development (HUD) provides expedited funding to assist communities in addressing urgent social needs. This program offers one-time cost-reimbursable grants for service coordination and direct services, especially in response to emergencies like natural disasters or public health crises. By streamlining the application process, the RRP empowers local leaders to efficiently support residents in HUD-assisted housing, promoting self-sufficiency and resilience.

The Computational Mathematics program supports research that integrates computation with mathematical analysis, encouraging innovative algorithm development and application. Proposals may range from individual projects to interdisciplinary teams, focusing on new computational techniques to address significant application challenges. The program also emphasizes training for junior mathematicians through hands-on research. Conference proposals must adhere to strict submission timelines to ensure review and funding opportunities, fostering collaboration within the mathematical sciences.

The NIAID aims to enhance infectious disease research by supporting human microphysiologic systems (MPS) development. These in vitro platforms mimic human tissue functions, promoting drug and biological product development while reducing animal use. This initiative aligns with NIH’s commitment to innovative research practices and regulatory acceptance. By focusing on MPS in infectious disease contexts, NIAID seeks to streamline therapeutic advancements and establish robust human tissue models, addressing critical challenges in understanding and treating infections.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing organ transplantation outcomes through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. This initiative supports multicenter clinical trials and mechanistic studies related to heart, lung, kidney, liver, and intestinal transplants, as well as non-hematopoietic cellular transplantation. By exploring immune mechanisms and innovative therapies, the program aims to enhance the success and efficacy of organ transplantation.

The REPI Challenge, initiated by the DOD's REPI Program, aims to protect critical testing and training capabilities through funded projects. Since 2012, over $193 million has been allocated to 69 initiatives, leveraging more than $512 million in partner contributions. The upcoming 2026 REPI Challenge will focus on strategic mission safeguarding, with up to $20 million available for preventing land use conflicts and enhancing military resilience, thus ensuring the longevity of vital defense capabilities.

The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.

The NIAID aims to enhance our understanding of the interplay between chronic and infectious diseases through innovative precision systems biology research. By utilizing advanced technologies such as multi-omics and artificial intelligence, the initiative focuses on uncovering critical pathways that connect infections to chronic health issues. This multidisciplinary approach leverages longitudinal patient data to inform and improve prevention and treatment strategies, ultimately seeking to provide insights into disease progression and host-pathogen interactions.

The Translational Transplantation Tolerance Cooperative Study Group, supported by the National Institute of Allergy and Infectious Diseases, aims to advance transplant tolerance strategies that promote long-term graft survival without lifelong immunosuppression. This initiative focuses on developing, optimizing, and evaluating methods to induce immune tolerance in allogeneic transplants through collaborative efforts across multiple centers, utilizing translationally relevant models to ensure effective outcomes.

The NIDDK Disorders of Gastrointestinal Interoception Consortium Clinical Centers (DGIC) aims to enhance understanding of gastrointestinal disorders by expanding the previous Gastroparesis Consortium's research scope. This initiative will include adult and pediatric conditions linked to impaired interoceptive processing, utilizing multidisciplinary approaches to uncover mechanisms connecting GI function to symptoms, identify biomarkers for treatment efficacy, and explore new therapeutic targets for future clinical trials.

The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Data Coordinating Center aims to enhance understanding of inflammatory bowel disease (IBD) by coordinating extensive genetic research. By leveraging diverse patient cohorts and advanced data science techniques, the center seeks to identify genetic risk factors, develop predictive biomarkers, and improve IBD patient management. This initiative will facilitate collaboration among various research centers and ensure efficient data collection and sharing to foster advancements in precision medicine for IBD.

The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) aims to enhance understanding of inflammatory bowel diseases (IBD) through genomic research. By leveraging patient cohorts and advanced data science, the IBDGC seeks to identify genetic risk factors and develop predictive biomarkers for disease outcomes. This initiative will improve medical management and advance precision medicine for IBD patients, addressing the need for effective diagnostics and treatment strategies in this chronic condition.

The NIDDK is expanding its Gastroparesis Consortium into the Disorders of Gastrointestinal Interoception Consortium (DGIC) to explore various GI disorders linked to interoceptive processing. This initiative aims to include multiple Clinical Research Centers and a Scientific Data Research Center, focusing on multidisciplinary approaches to uncover mechanisms connecting GI function to symptoms. The effort seeks to identify biomarkers and novel therapeutic targets for future clinical trials, enhancing understanding and treatment of complex gastrointestinal conditions.

The National Cancer Institute's PAIRS program aims to explore innovative cancer therapies by leveraging synthetic vulnerabilities that interact with tumor responses to radiation therapy. This initiative supports the development of targeted drug-radiation combinations, focusing on precision medicine to optimize treatment efficacy while minimizing harm to normal tissues. By consolidating prior funding opportunities, PAIRS encourages research that addresses context-dependent vulnerabilities, enhancing therapeutic strategies and aligning with NIH's scientific goals.

The BRAIN Initiative aims to advance the development of innovative therapeutic and diagnostic devices for disorders affecting the nervous system. This funding opportunity encourages small clinical studies and translational research to implement clinical prototypes, conduct safety testing, and obtain Investigational Device Exemptions. Participants will engage in a milestone-driven cooperative agreement with NIH staff to refine project plans and monitor progress, ensuring devices meet clinical needs and safety standards.

The BRAIN Initiative aims to advance next-generation devices for recording and modulation in the human central nervous system through small clinical trials. These trials will provide crucial information needed for the development of devices to treat CNS disorders. By enabling acute or short-term procedures, the initiative seeks to address significant questions related to device functionality and design, which are vital for future clinical trials and FDA approvals.

The BRAIN Initiative seeks innovative proposals for preclinical proof of concept studies on novel recording and modulation technologies aimed at diagnosing and treating central nervous system (CNS) disorders. This initiative supports diverse, multidisciplinary teams to enhance our understanding of the human CNS and prepare technologies for first-in-human studies. Applications are due by 5:00 PM local time, with optional Letters of Intent encouraged 60 days prior to the proposal deadline.

The Autism Centers of Excellence (ACE) initiative, spearheaded by the Eunice Kennedy Shriver National Institute for Child Health and Human Development along with several other prominent institutes, aims to encourage innovative research projects. While applications are not currently open, potential applicants are urged to prepare collaborative proposals that leverage cutting-edge technologies. This funding opportunity, utilizing the P50 Research Program Projects and Centers activity code, seeks to build upon over two decades of research advancements.

The Autism Centers of Excellence R01 aims to advance research in autism through collaborative networks, enhancing the past 23 years of progress. This initiative encourages innovative methods and technologies, inviting experts to consider applying for future funding opportunities. Although applications are not currently solicited, potential applicants are urged to form meaningful collaborations. This funding opportunity reflects a commitment to improving research in autism, leveraging diverse scientific expertise to address critical challenges in the field.

The AASM Foundation Disaster Relief Fund, established in 2005, provides essential financial aid to AASM accredited sleep centers impacted by natural disasters. By supporting these centers, the fund ensures that medical care remains accessible to patients during crises. Past funding has assisted centers after events like Hurricane Katrina and the 2010 Haiti earthquake, helping them recover and restore operations quickly. This initiative highlights the commitment to maintaining patient care in the face of adversity.

The Ron Chang Lee for Excellence in Classroom Technology award recognizes three TESOL members for their innovative use of technology in English Language Teaching. Established in 2018, the award offers prizes of $1000 for first place, $750 for second, and $500 for third. Eligible candidates must be TESOL members with at least two years of classroom experience and have designed the materials used for this award. Applications from certain countries may be ineligible due to international regulations.

The TESOL Award for Excellence in Research honors outstanding empirical research in language teaching and learning, promoting advancements in English language education. Sponsored by Dr. Deborah Short, this award includes a $1,500 grant, an additional $1,500 for conference expenses, a featured session at the TESOL convention, keynote speaking opportunity at the Graduate Student Forum, a one-year subscription to TESOL Quarterly, and a featured article in TESOL Connections.

The TESOL Teacher of the Year Award, presented by National Geographic Learning, honors exceptional English language teachers who have demonstrated outstanding dedication in the classroom for at least three consecutive years. The winner receives $1,000, a one-year TESOL membership, and free registration for the TESOL International Convention, including travel accommodations. This recognition not only highlights the importance of teaching excellence but also fosters a community of learning and collaboration among educators around the world.

The TESOL Leadership Mentoring Program connects TESOL members with experienced leaders for mentorship and professional development. Participants receive free registration to the annual convention, up to $1,000 for lodging, and the opportunity to build lasting relationships within the TESOL community. This program is designed for members in good standing, with a preference for individuals from underrepresented groups, fostering inclusivity and active participation in the association's initiatives.

About Borealis Philanthropy

Borealis Philanthropy is a philanthropic social justice intermediary that works to resource grassroots leaders and social justice movements for transformative change. We help funders expand their reach and strengthen their impact through donor collaboratives that support a variety of issues, communities, and movements. Borealis is home to nine donor collaboratives, including the Disability Inclusion Fund and Disability x Tech.

DIF x Tech Fund

For the Disability Inclusion Fund at Borealis, part of our efforts for disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. The DIF x Tech initiative, supported by the Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest, invites proposals that are working to bring about transformational change at the intersections of disability, justice, and technology

About the Disability Inclusion Fund and DIF x Tech

The Disability Inclusion Fund (DIF) supports U.S.-based groups run by and for people with disabilities to lead transformational change. The Fund is supported by donors including the Presidents’ Council on Disability Inclusion in Philanthropy, which is comprised of foundation presidents who are committed to disability inclusion as part of improving diversity, equity, and inclusion within philanthropy.

Part of the efforts of disability rights and justice includes the ways disability and technology are working towards shared goals in our movements. This newly launched initiative is housed at the Disability Inclusion Fund (DIF) and supported by Ford Foundation’s Technology & Society Program and the MacArthur Foundation’s Technology in the Public Interest. 

DIF x Tech Fund Values

All Disability x Tech award decisions will align with the DIF guiding values. The DIF guiding values are:

• Participation: Movement funding accountable to the disability rights movement. Those impacted by injustice/exclusion should be involved in strategies to advance justice/inclusion.
• Intersectionality: Acknowledging that disabled people have multiple and intersecting social and political identities that can influence their ability to have access and inclusion including race, gender identity, class, sexual orientation.
• Radical inclusion: Deeply committed to removing barriers and ensuring access so that those most affected by intersecting identities can participate, valuing lived experience.
• Leadership of those most impacted by ableism: Emphasis is given to organizations led by people subject to systemic bias and impacted by underrepresentation, particularly disabled people of color, queer, gender nonconforming and women with disabilities.
• Cross-movement solidarity: Intentional focus on collaboration and bridge- building amongst disability justice activists and across movements.
• Sustainability: Resources and tools that support the growth of grassroots disabled-led organizations, and expand operational capacities for ongoing movement building. 

What we fund

We invite proposals that are at the nexus of technology, disability rights and justice. This opportunity may be a good fit for your organization, if you are doing work in any of these areas below:

• Disabled people sharing technical skills and knowledge with others in the community.
• Disabled people leading policy, rights, and disability justice activism work related to tech. 
• Disabled people participate in all stages of the design and development of new tech that will enrich lives of people with disabilities.
• Enabling collective and equitable access to digital infrastructure. 
• Expanding the participation, leadership, and thought partnership of overlooked and under-resourced people with disabilities in all areas of the technology sector.
• Partnerships between disability-focused engineering design labs and maker spaces within schools, centers for independent living, or local nonprofit organizations.
• Permissible Policy Work:
  • We may support nonpartisan policy education and advocacy related to disability and technology. Any lobbying must remain within applicable 501(c)(3) limits and Borealis grant restrictions.

The National Institute of Nursing Research (NINR) plans to publish a funding opportunity announcement for Community-Partnered Nursing Research Centers (P20 Clinical Trial Optional). This initiative aims to strengthen nursing-led programs that foster community-partnered research addressing significant health issues. By enhancing interdisciplinary research capacities, the program will establish centralized resources in nursing schools, build expertise in community partnerships, and support nurse-led teams in developing, implementing, and evaluating impactful research projects.