Best Operating Grants for Nonprofits in Illinois

The Arthritis Foundation is seeking research proposals focused on Patient Reported Outcomes (PROs) to enhance shared decision-making in arthritis care. Projects should aim to deepen the understanding of patient treatment goals, monitor disease activity, and improve communication of PRO data. Research can span various arthritis types, including osteoarthritis and rheumatoid arthritis, and should last up to two years. This initiative emphasizes the integration of patient perspectives to elevate care quality.

The NIDCD Early Career Research (ECR) Award (R21) supports early-stage scientists in establishing independent research careers in areas such as hearing, balance, and language. This grant facilitates small, innovative research projects and aims to generate preliminary data for future R01 applications. It is not intended for thesis work and is designed to enhance research methodologies and technologies in biomedical and behavioral sciences. Applications are due by 5:00 PM local time of the applicant organization.

The Carol Pederson Music Scholarship, managed by the Ashland County Community Foundation, supports graduating seniors and recent graduates from Ashland County high schools or members of the Mansfield Youth Orchestra. Eligible applicants must maintain a GPA of at least 2.5 and pursue a music major or minor in string instruments. This scholarship aims to provide financial assistance to students passionate about music, reflecting Carol Pederson's commitment to education and community engagement.

The James W. Junior and Jane T. Brown Scholarship, established by Jane and James Brown in 2006, offers financial support to adult students over 21 in the Tri-Cities. This scholarship aims to ease the financial burdens faced by those returning to education. Applicants must demonstrate financial need and provide necessary documentation, including transcripts and a Student Aid Report. The program encourages recipients to assist others in their educational journeys, fostering a cycle of support in the community.

Shaw's Foundation Grants support nonprofit organizations that enhance community well-being, focusing on hunger, youth education, and health. Eligible organizations must be 501(c)(3) certified and serve specific regions like California and Hawaii. An employee sponsor is mandatory for applications in these areas. The grant review process typically takes about eight weeks, and the foundation prioritizes collaborations with local partners to maximize community impact.

The H. Wayne VanAgtmael Cosmetology Scholarship, established in 2005 by Wayne Van Agtmael's family, honors his legacy in the cosmetology field. This scholarship supports high school graduates from the Tri-Cities pursuing a cosmetology degree, focusing on financial need and academic achievement. Applicants must provide transcripts and additional required documents. The scholarship aims to empower students, particularly those who are the first in their families to succeed beyond high school, in their educational journeys.

The Pediatric Oncology Student Training (POST) Program Grant, offered by Alex’s Lemonade Stand Foundation, aims to foster the next generation of pediatric oncology researchers. This summer internship provides undergraduate, graduate, and medical students with hands-on research experience in a supportive environment, focusing on diversity and inclusion. Grants will specifically support students from underrepresented communities in the scientific workforce, enabling impactful research and mentorship opportunities to advance pediatric cancer care.

The Stout Foundation Grant supports organizations aligned with the values of its founder, Mr. Stout. Grants are awarded exclusively to entities with 501(c)(3) tax-exempt status and focus on charitable, educational, and scientific purposes. Preference is given to organizations with low overhead costs and those located in areas frequented by Foundation members. The Foundation aims to promote effective use of funds while remaining flexible in its grant-making approach.

The Eppley Foundation for Research, established in 1947, supports advanced scientific research in chemistry, physics, and biology. It prioritizes innovative studies, particularly in medical investigations and climate change. The foundation does not fund social sciences or projects with ample existing financial support. Applicants must hold a PhD or MD and be associated with a nonprofit in the US. The foundation aims to foster groundbreaking research that is unlikely to be replicated elsewhere.

The Howard D. Colman Scholarship supports high school seniors from Boone and Winnebago Counties pursuing degrees in engineering or technology fields. Established in memory of entrepreneur Howard D. Colman, the scholarship offers $2,500 in the first year, with potential renewal up to $10,000 for three additional years, contingent on meeting criteria. Recipients gain hands-on experience through internships with local firms, fostering connections to the Rockford area.

The NNLM Region 5 Professional Development Award offers funding for individuals at member institutions to enhance their knowledge and skills in health-related areas. This initiative aims to support meetings, workshops, and training that focus on health literacy, public health, and evidence-based practices. By fostering professional development, the NNLM seeks to improve healthcare services and access to health information across various communities, ultimately contributing to better public health outcomes.

Howard Hughes Medical Institute

More than 70 years ago, the Howard Hughes Medical Institute (HHMI) was founded with a mission to advance basic biomedical research and science education. Today, we invest in exceptional scientists at all career stages, catalyzing breakthroughs, new technologies, and the next generation of transformative clinical therapies. Our pathbreaking science takes place at more than 60 host institutions across the US, and at our Janelia Research Campus.

Cech Fellows Program

The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders. 

The Summer Undergraduate Research Program (the Cech Fellows Program) gives undergraduate students in the life sciences the opportunity to conduct hands-on research alongside leading scientists at HHMI laboratories across the US, from universities and research institutions to HHMI’s research campus outside of Washington, DC. Students are matched with HHMI scientists conducting fundamental research that advances our understanding of biology and health.

This immersive program gives students the chance to contribute to real scientific discovery, gain professional mentorship, and explore potential careers in biological and biomedical research.

Gain Hands-On Experience in Research & Lab Work

Through the summer, students will:

• Work full time conducting research and contributing to ongoing projects in an HHMI laboratory
• Learn and practice new techniques and approaches in disciplines such as cell biology, genetics, neuroscience, and more
• Work closely with and be mentored by exceptional scientists, from lab heads to PhD students
• Build critical thinking and communication skills necessary for future research careers

What the Program Offers

Beyond meaningful lab work, the program provides:

• A stipend to support summer travel, housing, and living expenses 
• An opportunity for participants to present their research and connect with a national cohort of peers at an end-of-summer research symposium at HHMl’s research campus outside of Washington, DC 
• An engaging virtual seminar series with HHMI scientists as well as professional development sessions focused on relevant skills building

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

• Promote and support legal research and education;
• Advance the science of jurisprudence;
• Facilitate the administration of justice;
• Foster improvements in the practice of Federal law

Foundation Grants

Foundation grants support community service projects and civics programs which comply with the Foundation’s mission to promote and support legal research and education; advance the science of jurisprudence; facilitate the administration of justice; and foster improvements in the practice of Federal law.

Civics Education Grant

The Civics Grant Program is designed to support projects and initiatives that promote a wider public understanding of democratic principles, the judicial system and the rule of law. Through targeted funding, the program empowers FBA chapters, sections, divisions, national standing committees (FBA entity), and other organizations to develop and support projects in their communities that foster public understanding of the rights and responsibilities of American citizenship, particularly among younger Americans.

Applicants may only receive one (1) Foundation grant per year.

The Inspire Grants for Small Museums (2027) initiative, funded by the Institute of Museum and Library Services, aims to empower small museums across various disciplines. This program focuses on project-based funding to enhance public service through educational programs, exhibits, and community partnerships. By supporting small, often underfunded institutions, Inspire seeks to strengthen their capacity to engage communities and improve collections management, fostering experiential learning and discovery.

The Mellon Foundation Long-Term Fellowships, hosted by the Newberry Library, offer scholars the opportunity to engage deeply with its extensive collections. This fellowship supports innovative research across various disciplines, allowing recipients to immerse themselves in the library's rich historical resources for four to nine months. International scholars are welcome, and applications are encouraged from those proposing effective use of the Newberry’s collections. This initiative fosters a vibrant community of learning and discovery.

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Scholarships

Cherokee Nation Foundation offers a diverse range of scholarships to help reverse the trend of rising student debt. Students may receive up to two CNF scholarships per academic year. All opportunities are reserved for Cherokee Nation citizens, unless otherwise noted in the description.

Senior Master Sergeant Texie C. Taylor, USAF Memorial Scholarship

Applicant must be a junior or senior undergraduate or graduate student majoring in physics, chemistry, biology, medicine, nursing (RN), engineering (aerospace, civil, chemical, electrical, mechanical) or mathematics with a minimum 3.0 GPA. This is a one-year scholarship reserved for Cherokee Nation citizens residing within the Cherokee Nation jurisdictional area.

The Thad G. Gayman Memorial Scholarship Fund honors Thad Gayman, a dedicated automotive technician and Northern York High School alumnus who tragically passed away at age 23. Established to support students in automotive technology, this fund emphasizes academic achievement, financial need, and a commitment to the field. Extra consideration is given to graduates from Northern York High School. This one-time scholarship aims to empower future automotive professionals in honor of Thad's legacy.

The SHAPE America: Joy of Effort Award recognizes dedicated individuals who exemplify the spirit of commitment and passion in health and physical education. Awardees are current SHAPE America members with at least three years of membership, demonstrating excellence in teaching, coaching, or leadership. This prestigious award celebrates those who have made significant contributions to the field, inspiring others to lead healthy, active lives through their efforts in education and advocacy.

The NASGA Research Grants aim to enhance strawberry production sustainability in North America by addressing critical research priorities, including cultivar development, pest management, and production efficiency. Proposals that improve fruit quality, reduce environmental impacts, and align with growers' needs are prioritized. The program welcomes submissions from all researchers, with a focus on innovative solutions that promote economic viability and environmental stewardship in the strawberry industry.

The Louise Wachter Wickham Scholarship, established in 1997 by Donna Wickham Furth, supports high school seniors pursuing a degree in elementary education. This scholarship is awarded based on financial need and academic performance. Recipients must demonstrate commitment to education and may need to submit additional documents such as transcripts and recommendation letters. The fund honors Louise Wachter Wickham, a dedicated teacher who believed in the transformative power of education.

Monarch Watch offers a Free Milkweeds Grant for habitat restoration projects aimed at supporting the monarch butterfly population. The program provides free milkweed plugs to schools and educational non-profits that demonstrate clear educational goals, long-term maintenance plans, and adequate space for the plants. With over 730,000 milkweeds distributed since 2015, this initiative plays a vital role in restoring habitats along key migration routes in the eastern and western U.S.

About Us

Our Mission

The Marfan Foundation drives research, education and support – and builds community – to improve outcomes, save lives and empower all people to thrive who are living with Marfan, Loeys-Dietz, Vascular Ehlers-Danlos syndromes, and related genetic aortic and vascular conditions.

Our Vision

Quality of life, longevity, and cures for all people with genetic aortic and vascular conditions.

Innovators Award

This is for faculty investigators for $100,000 over 2 years ($50,000 per year), to explore an innovative concept in “translational” science that has applicability to improving human health. Examples could include fundamental research, diagnostic tests, biomarkers, biomedical engineering advances, and imaging advances. Collection of data for improved evidence-based medical guidance are of great interest.

The Urban Indian Health Program - Education & Research collaborates with the US Dept. of Health & Human Services to enhance educational and research opportunities for urban Indian populations. This initiative aims to address health disparities and ensure that urban Indians have access to quality health services and information. By partnering with various urban Indian organizations, the program fosters community engagement and empowers individuals through education and research, ultimately improving health outcomes.

The National Institutes of Health (NIH) is dedicated to advancing emergency care through the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN). This initiative seeks to establish clinical enrollment hubs that will enhance the network's ability to conduct trials aimed at improving outcomes for patients experiencing neurological and cardiovascular emergencies. Although applications are not currently being accepted, this notice encourages potential applicants to prepare collaborative and impactful proposals.

About AWS

We Move Welding Forward

Founded in 1919, the American Welding Society is a nonprofit organization with a global mission: to advance the science, technology, and application of welding and allied joining and cutting processes worldwide, including brazing, soldering, and thermal spraying.

By fostering knowledge, embracing change, and providing real-world opportunities through scholarships, fellowships, and workforce development, AWS provides the tools to help members succeed—and to inspire future generations of welding professionals.

AWS Future Leaders Program 2026

Become an AWS Future Leader

The AWS Future Leaders Program is a career-transforming opportunity for early-career professionals looking to step into leadership within the welding industry.

Gain unparalleled access to industry experts, contribute to AWS’s governance, and shape the future of welding. Our mission is to empower the next generation of leaders with diverse perspectives, ensuring the welding industry reflects the needs of tomorrow.

Why join the AWS Future Leaders Program

Shape the future of welding. Gain mentorship, leadership experience, and industry connections while representing the next generation of welding professionals.

The Access To Recreation Endowment Fund Grant, managed by the Community Foundation for the Land of Lincoln, supports nonprofit organizations in Sangamon County that provide accessible recreation programs for individuals with disabilities. This initiative, initially funded by the W.K. Kellogg Foundation, aims to enhance participation in adaptive sports and activities, ensuring that everyone has the opportunity to engage in both indoor and outdoor recreation without barriers.

The North Lawndale Fresh Grant Program, managed by the Lumpkin Family Foundation, promotes health and wellness by supporting local food-related initiatives. It aims to enhance the North Lawndale economy through culinary enterprises, improve green spaces, and provide culturally relevant nutrition education. The program encourages collaboration among community members and organizations, fostering innovative approaches to food access and emergency assistance. This initiative embodies the foundation's commitment to community service and leadership development within North Lawndale.