Upcoming Webinar
How Funders Feel About AI, and What Keeps Them Saying Yes.
Wed, Oct 14 @ 2PM ET

Skip to main content
Main content

Best Mackinac County Grants for Nonprofits in Michigan

Looking for grants for 501(c)(3) nonprofit organizations working in Mackinac County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.60B

Total funding

$5K

Median grant

9,000+ grants
$2.60B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,343 Results based on applied filters

NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required) (357492)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,050,000
The NCCIH Natural Product Early Phase Clinical Trial Award supports innovative clinical trials of natural products, such as botanicals and dietary supplements, with a strong scientific basis. Applications are encouraged to explore optimal delivery methods and combinations with other treatments. Funding is available for up to three years to assess the impact on target engagement and clinical outcomes, aiming to translate basic science findings into practical clinical applications.
Food Safety Drug Safety

Limited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional) (357632)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,500,000
The Limited Competition K12 Mentored Research Career Development Program aims to support institutions in developing innovative career pathways for later-stage postdoctoral fellows and junior faculty. This initiative encourages applicants from those with existing Clinical and Translational Science Awards (CTSA) to foster independent research careers. By creating diverse opportunities across academia, industry, and government, the program enhances engagement in clinical and translational science research, ultimately contributing to significant advancements in health outcomes.
Medical Education & Professional Training Science Biology +1 more

U.S. Writers Aid Initiative Grant

PEN America
Private
United States
Unspecified amount

U.S. Writers Aid Initiative

PEN America is an organization of writers and their allies, and that solidarity is never more important than when members of our literary community face crises. PEN America’s U.S. Writers Aid Initiative, part of the PEN America Writers Emergency Fund, offers grants for writers in the United States facing acute financial need following an emergency situation.

The U.S. Writers Aid Initiative is intended to assist fiction and nonfiction authors, poets, playwrights, translators, and journalists in addressing short-term financial emergencies. To be eligible, applicants must be professional writers based in the United States, and be able to demonstrate that this one-time grant will be meaningful in helping address a short-term emergency situation. The fund is limited, and not every application can be supported.

Grant decisions are made on a quarterly basis by a volunteer committee of literary peers in consultation with PEN America staff, using the following guidelines to evaluate professional credentials:

  • Publication of one or more books. (Writers who are only self-published or published by a press that charges for publication are not eligible.)
  • Multiple essays, short stories, or poems appearing in literary anthologies or literary journals (either online or in print) in the last two years.
  • A full-length play, performed in a theater by a professional theater company. Productions in academic settings qualify if the author is not a student at the time of the production.
  • Employment as a full-time professional journalist, columnist, or critic, or a record of consistent publication on a freelance basis in a range of outlets during the last two years.
  • Contracted forthcoming books, essays, short stories, poems, or articles for which the name of the publisher can be provided.
  • Other qualifications that support the applicant’s professional identity as a writer.
Writing & Literature

AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer (Fund B)

American Gastroenterological Association
Association/Society
North America
US $300,000
The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty in digestive disease research. This award aims to support independent careers in pancreatic cancer research by protecting a significant portion of the recipient's time for research activities. Eligible applicants must hold an MD, PhD, or equivalent and work at a North American institution, with AGA membership required. Strong encouragement is given to underrepresented groups.
Pancreatic Cancer

AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer (Fund A)

American Gastroenterological Association
Association/Society
North America
US $300,000
The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty focused on independent research in pancreatic cancer. This award aims to protect at least 50% of the recipient's time for research activities. Eligible applicants must hold an MD or PhD and be classified as early-career. The award encourages physician-scientists and underrepresented groups in biomedical research to apply, supporting innovative research that can lead to significant advancements in understanding pancreatic cancer.
Pancreatic Cancer

AGA-Gastric Cancer Foundation Ben Feinstein Memorial Research Scholar Award in Gastric Cancer

American Gastroenterological Association
Association/Society
North America
US $300,000
The AGA-Gastric Cancer Foundation Ben Feinstein Memorial Research Scholar Award provides $100,000 annually for three years to early-career faculty dedicated to gastric cancer research. Eligible candidates must have an MD, PhD, or equivalent and a full-time faculty position in North America. The award supports research in various areas related to gastric cancer, ensuring a minimum of 50% time commitment to the project, thus fostering independent careers in digestive diseases.
Gastrointestinal Cancers

Postdoctoral Fellowships

American Diabetes Association Inc
Private
American Samoa, Guam +4 more
US $84,008 - US $252,024
The American Diabetes Association's Postdoctoral Fellowship Awards aim to foster emerging leaders in diabetes research. With a focus on innovative research, these fellowships provide up to three years of funding, including a stipend and allowances. Eligible applicants must hold a recent advanced degree and conduct research at U.S. affiliated institutions. This initiative not only supports career development but also contributes significantly to the mission of preventing and curing diabetes.
Diabetes

Zuckerman Postdoctoral Scholars Program: Joint North American-israel Postdoc Track

Mortimer B Zuckerman Foundation
Private
Canada, Israel +1 more
Up to US $126,000
The Zuckerman Postdoctoral Scholars Program fosters collaboration between leading scientific institutions in the U.S. and Israel by attracting top postdoctoral researchers. With a focus on STEM leadership, this program offers a unique two-year scholarship, allowing scholars to conduct research at participating Israeli universities and North American institutions. The initiative aims to strengthen academic ties, enhance research capabilities, and support the return of talented Israeli scholars to their home institutions, ultimately enriching the global scientific community.
Engineering Mathematics Science +1 more

Tides Stronger Together Fund Grant

Tides Foundation
Private
United States
Unspecified amount
The Tides Stronger Together Fund, under the Tides Foundation, provides essential support grants to fiscally sponsored partners focused on historically underserved communities. By building organizational capacity and leadership, the fund empowers community changemakers to address inequities and enhance sustainability. With a pooled funding model, it directly responds to the needs of over 120 partners, ensuring resources are effectively allocated where they are most impactful, ultimately fostering long-term community resilience.
Community Services

Goldman Fund: Democracy & Civil Liberties

Lisa & Douglas Goldman Fund
Private
United States
Unspecified amount
The Lisa and Douglas Goldman Fund, established in 1992, supports charitable organizations that enhance society, focusing on democracy and civil liberties. The fund prioritizes projects that ensure equal citizen participation in the democratic process and protect civil liberties, especially those implemented nationally or across multiple states. It operates by invitation only and emphasizes flexible, informed grantmaking to qualified projects that align with its mission and values.
Governance & Democracy Civic Engagement & Education Gun Violence Prevention +1 more

HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed) (357655)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The HEAL Initiative aims to identify new druggable targets for pain within the understudied proteome. This funding opportunity invites applications for pilot projects that generate preliminary data and tools for exploring these targets. The initiative seeks to enhance research on understudied proteins related to pain management, providing essential funding for biochemical and biological work. This NOFO is part of the NIH's broader effort to develop novel medications that address various aspects of opioid addiction and its consequences.
Chronic / Acute Pain Anesthesia and Pain Medicine Drug Use Disorder +1 more

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) (357658)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The Limited Competition Small Grant Program under the NCATS CTSA aims to enhance the research capabilities of scholars transitioning to independent academic translational scientists. This program supports diverse clinical and translational science projects, including pilot studies and methodology development. The R03 grants are designed for short-term projects with limited resources that generate preliminary data for future R01 applications, thereby fostering innovation and advancing health research.
Science Biology Health & Medicine +2 more

Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) (357667)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,250,000
The Limited Competition: Clinical and Translational Science Award (CTSA) Program's Collaborative and Innovative Acceleration Award aims to enhance translational research by fostering collaboration in developing and implementing innovative solutions. This funding opportunity invites applications focused on new approaches and technologies that will improve research impact across various diseases and expedite treatment availability. Eligible applicants include organizations with active CTSA hub prime or partnering awards.
Health & Medicine Pharmacology Biomedical informatics +4 more

Outdoor Recreation Legacy Partnership Program (ORLP) Recurring Notice 5 Year

US Department of the Interior: National Park Service (NPS)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $15,000,000
The Outdoor Recreation Legacy Partnership Program (ORLP) is a competitive grant initiative by the National Park Service, aimed at enhancing parks and recreational opportunities in urban, underserved communities. This program supports the acquisition, development, and renovation of outdoor recreation areas through federal funding, addressing the needs of community organizations, local governments, and recognized tribes. Applications are accepted twice a year, before June 1 and November 1.
Parks & Public Spaces Outdoor Recreation Outdoor Equity

Environmental Justice Thriving Communities Grantmaking Program: Tier 1

The Minneapolis Foundation
Private
Illinois, Indiana +4 more
Up to US $150,000
The Environmental Justice Thriving Communities Grantmaking Program, led by The Minneapolis Foundation, supports community-based nonprofits in the Great Lakes region. With a focus on underserved communities, grants will total $40 million over three years, aiming to enhance environmental health, education, and resilience. The program prioritizes applications from federally recognized tribes and organizations with limited budgets, fostering inclusive community engagement and sustainable development. Eligible projects include environmental assessments, public health initiatives, and job training.
Environmental Justice & Advocacy Environmental Health Green Infrastructure +5 more

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 1

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) Funding Announcement aims to enhance methods for conducting patient-centered comparative clinical effectiveness research. This initiative seeks to address critical methodological gaps, focusing on improving the use of artificial intelligence in clinical research, study design, data research networks, and ethical protections in patient-centered CER. With a budget of up to $750,000, successful proposals will contribute to the quality and strength of evidence generated in CER studies.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding Announcement - Cycle 2

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is offering funding up to $750,000 for studies aimed at addressing critical methodological gaps in patient-centered comparative clinical effectiveness research. This initiative focuses on enhancing the quality of evidence in clinical research by prioritizing areas such as artificial intelligence, study design improvements, support for data research networks, and ethical considerations. Successful proposals will contribute to advancing research methodologies and improving patient outcomes.
Medical Ethics Artificial Intelligence (AI) Health & Medicine

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding - Cycle 3

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $750,000
The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.
Health & Medicine Medical Ethics Artificial Intelligence (AI)

Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Risk and Protective Factors of Family Health initiative invites research proposals to explore family health and resilience, addressing health disparities in minority communities. Key submission deadlines are set for various dates from February 2025 to February 2027. This program is supported by the National Institutes of Health, highlighting the importance of family well-being as a critical area for advancing health equity. Proposals should focus on interventions that improve family health outcomes.
Family Services Minority Services Health Disparities & Social Determinants of Health

MACC: Experience Support Grant Program - Facility Improvement & Equipment

Michigan Arts and Culture Council (MACC)
State/Local Government
Michigan
Up to US $30,000

Experience Support Grant Program

The Experience Support grant program provides arts and culture-related project funding to Michigan organizations for which arts and culture is not the primary focus of the organization’s mission. Eligible applicants include municipalities, tribal entities, PreK-12 schools, colleges/universities, and non-arts/culture 501(c)(3) nonprofits. Applicants can submit one grant application to request funding in any/all of these categories: Project Support, Facility Enhancement & Equipment Purchase, Professional/Organizational Development and Transportation.

Facility Improvement & Equipment

Facility Improvement & Equipment funding is designed to assist organizations with both facility improvements and/or the purchase of equipment related to the arts and culture programming, services, and/or activities the organization provides to its audiences and communities. Organizations may request any combination of facility improvement and/or equipment needs up to the maximum request amount. Organizations applying for Facility Improvement needs must have proof of ownership of the building or evidence of a long-term lease.

  • Allowable Expenses:
    • Expansion, renovation, or construction of applicant-owned cultural facilities
    • Facility structure or system maintenance of applicant-owned cultural facilities
    • Feasibility studies, architectural drawings/fees, and design fees
    • Construction and project management costs
    • Purchase of equipment directly related to the organization’s arts/cultural production 

Art & Culture

Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to address the urgent mental health crisis in the U.S. by promoting research that enhances access to evidence-based practices for youth. It encourages applications focusing on interventions for underserved populations, including those facing housing and food insecurities. Researchers are invited to explore strategies for improving service delivery, overcoming workforce challenges, and integrating care into accessible settings, ultimately striving for equitable mental health services for all youth.
Mental Health & Psychiatric Diseases Children’s Mental Health

MACC: Experience Support Grant Program - Professional & Organizational Development

Michigan Arts and Culture Council (MACC)
State/Local Government
Michigan
Up to US $1,500

Experience Support Grant Program

The Experience Support grant program provides arts and culture-related project funding to Michigan organizations for which arts and culture is not the primary focus of the organization’s mission. Eligible applicants include municipalities, tribal entities, PreK-12 schools, colleges/universities, and non-arts/culture 501(c)(3) nonprofits. Applicants can submit one grant application to request funding in any/all of these categories: Project Support, Facility Enhancement & Equipment Purchase, Professional/Organizational Development and Field Trips.

Professional & Organizational Development

Professional/Organizational Development funding is designed to assist an organization in providing arts and culture-related educational opportunities that increase the knowledge and skills of the organization’s personnel. Only staff members, contracted employees, board members, and/or volunteers may be selected to participate in the organization’s Professional/Organizational Development request.

  • Allowable Expenses:
    • Registration fees directly related to an in-person or virtual professional development opportunity including conferences, training, or certification
    • Consultant fees directly related to organizational development opportunities including strategic planning, coalition building, fundraising planning, needs assessment, grant writing, and board governance
    • Travel (in OR out-of-state) including meals and lodging
    • Materials directly related to the professional development opportunity

Art & Culture

MACC: Experience Support Grant Program - Field Trips

Michigan Arts and Culture Council (MACC)
State/Local Government
Michigan
Up to US $1,500

Experience Support Grant Program

The Experience Support grant program provides arts and culture-related project funding to Michigan organizations for which arts and culture is not the primary focus of the organization’s mission. Eligible applicants include municipalities, tribal entities, PreK-12 schools, colleges/universities, and non-arts/culture 501(c)(3) nonprofits. Applicants can submit one grant application to request funding in any/all of these categories: Project Support, Facility Enhancement & Equipment Purchase, Professional/Organizational Development and Transportation.

Field Trips

Field trip funding is designed to assist organizations that have a need to transport participants in “field trip” style events to engage in arts and cultural programming/services/activities. The transportation costs may be associated with both in-state and out-of-state travel. The transportation funding may be related to (or may be separate from) any other project applied for within this Experience Support grant application.

The funding may be used in one (or both) of the following ways:

  • Transporting a group of participants to the applicant’s venue to participate in the applicant’s arts and cultural programming/services/activities.
  • Transporting a group of the applicant’s participants to a different organization’s venue to participate in arts and cultural programming/services/activities. 

Art & Culture

NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08) aims to enhance the careers of clinical scientists committed to cancer research. This NIH-supported program provides protected time for research and encourages underrepresented individuals in health-related sciences. With deadlines spanning from 2025 to 2027, the program focuses on training and developing the skills necessary to compete for significant research funding and address health disparities in cancer research.
Cancer / Oncology Medical Education & Professional Training

Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional) (357550)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.
Cancer / Oncology Liver Disease Health Disparities & Social Determinants of Health

NIMH Career Transition Award for Tenure-Track Intramural Investigators (K22 Independent Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $600,000
The NIMH Career Transition Award (K22) supports tenure-track intramural investigators at NIMH in their transition to independent research faculty positions. This program aims to foster innovative research in mental health, encouraging applicants with a strong record of research excellence. Key deadlines for applications vary, including those for standard and renewal submissions, emphasizing the importance of timely applications to secure funding and advance mental health research initiatives.
Biology Health & Medicine Medical Education & Professional Training +1 more

Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional) (357572)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Interventions to Reduce Sleep Health Disparities (R01) grant aims to fund non-pharmacological strategies that enhance sleep health and address disparities in sleep among affected populations. The program emphasizes innovative approaches to examine sleep as a crucial element in mitigating health disparities across various health outcomes. Deadlines for applications range from February 2025 to June 2027, supporting both standard and renewal submissions under the National Institutes of Health.
Health Disparities & Social Determinants of Health Sleep

Mackinac County Grants for Nonprofits Highlights

Looking for Mackinac County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Mackinac County grants recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Michigan

Average Grant Size

What's the typical amount funded for Michigan?

Grants are most commonly $89,949.

$89,949

Total Number of Grants

What's the total number of grants in Mackinac County Grants for Nonprofits year over year?

In 2024, funders in Michigan awarded a total of 65,465 grants.

2022 59,390

2023 60,659

2024 65,465

Top Grant Focus Areas

Among all the Mackinac County Grants for Nonprofits given out in Michigan, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Mackinac County Grants for Nonprofits changing over time?

Funding has increased by 4.77%.

2022 $5,494,510,387

2023 $5,608,918,451
2.08%

2024 $5,876,731,534
4.77%

Michigan Counties That Receive the Most Funding

How does grant funding vary by county?

Wayne County, Kent County, and Oakland County receive the most funding.

County Total Grant Funding in 2024
Wayne County $1,257,959,859
Kent County $782,573,802
Oakland County $610,681,665
Washtenaw County $550,205,535
Calhoun County $444,453,435

Related Grants in Michigan

Browse Grants by Cities within Michigan

Browse Grants by Counties within Michigan