Best Large Grants for Nonprofit Organizations in Minnesota

Friends of NRA

Friends of NRA is the National Rifle Association’s premier fundraising program, supporting the future of shooting sports. Since day one, Friends of NRA has been a 100% grassroots effort fueled by a united front to secure the Second Amendment and raise money for the shooting sports.

Committee volunteers are appointed to State Fund Committees to make recommendations for local grant funding in areas such as youth education, women-focused clinics, law enforcement training, hunter safety, range improvement, firearms and marksmanship training and safety. Recognizing the impact American youth has on the future of the shooting sports, State Fund Committees frequently recommend grants for youth programs, allocating the most significant portion of monies to this vital area.

Grant awards fund activities and support programs in the United States to promote firearms and hunting safety, to enhance marksmanship skills of those in the shooting sports, and to educate the public about firearms in their historic, technological and artistic context.

Friends of NRA State Fund Grant Program - Minnesota

The Friends of NRA State Fund Grant Program provides supplies, equipment, and financial support to a variety of qualified groups and programs at the local level; geared towards youth, women, law enforcement, veterans, the disabled, and the general public, including:

• General shooting programs
• Competitive shooting
• Education, training and safety
• Hunting and conservation
• Community outreach
• Historical education

Grant funding must be used to further a charitable purpose as defined by the Internal Revenue Code under section 501(c)(3) and accompanying rules, regulations, and other IRS law and materials.

Midwest Nursing Research Society (MNRS)

The MNRS originally began to provide a place for nurses to collaborate, and collaborate they did! Over time, the founding members began to realize the benefits of having an organization dedicated specifically to nursing research. With some careful attention and a lot of hard work, we have grown into the organization it is today. We're a society where scientists, innovators, and drivers of clinical practice across the career trajectory, come together to share ideas and grow our field through innovative research.

The mission of the MNRS is to generate knowledge, translate evidence into practice, and enhance careers through collaborative engagement, implementation, and dissemination among diverse scholars. Our Vision to be the premier society that advances science, fosters leadership, and drives dissemination to improve health equity for all people.

It is an honor to recognize the important contributions of our nursing colleagues. MNRS accepts nominations for our five very prestigious awards to selected members of the Society who have made significant and notable contributions to the field of nursing through research. 

Harriet H. Werley New Investigator Award

The purpose of the Harriet H. Werley New Investigator Award is to recognize the scientific contribution of a new investigator who has conducted nursing research that has the potential to enhance the science and practice of nursing.

Midwest Nursing Research Society (MNRS)

The MNRS originally began to provide a place for nurses to collaborate, and collaborate they did! Over time, the founding members began to realize the benefits of having an organization dedicated specifically to nursing research. With some careful attention and a lot of hard work, we have grown into the organization it is today. We're a society where scientists, innovators, and drivers of clinical practice across the career trajectory, come together to share ideas and grow our field through innovative research.

The mission of the MNRS is to generate knowledge, translate evidence into practice, and enhance careers through collaborative engagement, implementation, and dissemination among diverse scholars. Our Vision to be the premier society that advances science, fosters leadership, and drives dissemination to improve health equity for all people.

It is an honor to recognize the important contributions of our nursing colleagues. MNRS accepts nominations for our five very prestigious awards to selected members of the Society who have made significant and notable contributions to the field of nursing through research. 

Distinguished Contribution Award

The purpose of the Distinguished Contribution Award is to recognize the scientific contribution of a member who has conducted or promoted research, which has enhanced the science and practice of nursing in the MNRS region.

The Community Homeownership Impact Fund, managed by the Minnesota Housing Finance Agency, aims to enhance affordable housing in Minnesota by funding developers and administrators of single-family, owner-occupied homes. This program focuses on increasing the housing supply while ensuring safety and habitability. It offers interim loans, deferred forgivable loans, and grants to bridge financial gaps. Eligible applicants include cities, tribes, and nonprofits, all working towards improving housing accessibility and supporting community development.

The Community Clinic Grant, funded by the Minnesota Department of Health, aims to enhance mental health services for all ages, improve oral health programs, and provide clinical services for at-risk youth up to 25 years old. This initiative emphasizes collaborative practice among dental hygienists in community settings to expand access to essential health services, thereby addressing critical healthcare needs in vulnerable populations. Funding is available for projects that meet these objectives.

The National Sea Grant Law Center is inviting proposals for the Coastal Resilience Program to research laws and policies addressing coastal resilience challenges such as sea level rise and flooding. With a funding cap of $150,000 over two years, this initiative aims to assess the effectiveness of existing policies and promote informed decision-making in coastal management. Up to two projects will be selected for funding, supporting innovative solutions to enhance community resilience against environmental threats.

Midwest Nursing Research Society (MNRS)

The MNRS originally began to provide a place for nurses to collaborate, and collaborate they did! Over time, the founding members began to realize the benefits of having an organization dedicated specifically to nursing research. With some careful attention and a lot of hard work, we have grown into the organization it is today. We're a society where scientists, innovators, and drivers of clinical practice across the career trajectory, come together to share ideas and grow our field through innovative research.

The mission of the MNRS is to generate knowledge, translate evidence into practice, and enhance careers through collaborative engagement, implementation, and dissemination among diverse scholars. Our Vision to be the premier society that advances science, fosters leadership, and drives dissemination to improve health equity for all people.

It is an honor to recognize the important contributions of our nursing colleagues. MNRS accepts nominations for our five very prestigious awards to selected members of the Society who have made significant and notable contributions to the field of nursing through research.

MNRS Lifetime Achievement Award

The Lifetime Achievement Award recognizes an MNRS member who has significantly advanced the profession of nursing either through an extensive program of research or creation of environments where research can flourish, and whose sustained leadership and distinguished career yielded outstanding and noteworthy accomplishments. 

What does this program do?

It provides loans and grants to Microenterprise Development Organizations (MDOs) to:

• To help microenterprises startup and growth through a Rural Microloan Revolving Fund.
• Provide training and technical assistance to microloan borrowers and micro entrepreneurs.

Microenterprise Development Organizations must demonstrate experience in managing a Revolving Loan Fund, or:

• Certify that it or its employees have received education and training from a qualified microenterprise development training entity so that the applicant has the capacity to manage such a revolving loan fund.
• Demonstrate that it is actively and successfully participating as an intermediary lender in good standing under the U.S. Small Business Administration (SBA) Microloan Program or other similar loan programs as determined by the Administrator.

 What kind of funding is available?

• Grants are available to provide technical assistance to rural micro-entrepreneurs or microenterprises, up to $205,000 annually. Funding at the requested level is not guaranteed, and at least 15 percent matching funds are required.

• Loans of $50,000 to $500,000 may be used for establishing a Rural Microloan Revolving Fund managed by the Microenterprise Development Organization.
• Total aggregate debt is capped at $2.5 million.

What are the loan terms?

• Maximum term is 20 years.
• Two-year payment deferral.
• Must establish a loan loss reserve fund.

What terms are required on loans to ultimate recipients?

• Up to $50,000.
• Fixed interest rate.
• Limited to 75 percent of project cost.

How may the funds be used?

Microlenders may make microloans for qualified business activities and expenses including, but not limited to:

• Working capital.
• Debt refinancing.
• Purchasing equipment and supplies.
• Improving real estate.

Midwest Nursing Research Society (MNRS)

The MNRS originally began to provide a place for nurses to collaborate, and collaborate they did! Over time, the founding members began to realize the benefits of having an organization dedicated specifically to nursing research. With some careful attention and a lot of hard work, we have grown into the organization it is today. We're a society where scientists, innovators, and drivers of clinical practice across the career trajectory, come together to share ideas and grow our field through innovative research.

The mission of the MNRS is to generate knowledge, translate evidence into practice, and enhance careers through collaborative engagement, implementation, and dissemination among diverse scholars. Our Vision to be the premier society that advances science, fosters leadership, and drives dissemination to improve health equity for all people.

It is an honor to recognize the important contributions of our nursing colleagues. MNRS accepts nominations for our five very prestigious awards to selected members of the Society who have made significant and notable contributions to the field of nursing through research.

The Excellence in Diversity, Equity, & Inclusion Award

The purpose of the Excellence in Diversity, Equity, and Inclusion Award is to recognize the contribution of a member who has demonstrated outstanding commitment and made significant contributions to advance equitable health outcomes and reduce health disparities through research, which has enhanced the science and practice of nursing in the MNRS region.  

The W R Berkley Corporation Charitable Grant Program supports local 501(c)(3) organizations in Central Iowa, SW Minnesota, and Eastern Nebraska. With a focus on health, community betterment, youth development, education, and food insecurity, grants are awarded twice a year. There are no limitations on request sizes, but only one grant per organization is accepted annually. Funding decisions prioritize organizations with a proven track record of efficiency and success in serving their communities.

The Indian Health Grant Program aims to provide essential clinical health services, including preventive, medical, dental, and mental health care, to American Indian individuals residing off reservations. Funded by the Minnesota Department of Health, up to $174,000 is available annually through a competitive process for a two-year project period from January 1, 2025, to December 31, 2026, with no match requirement necessary.

The Karen Colina Wilson Foundation Grant supports programs for children, youth, and women, enhancing their health and well-being through education, art, literature, and music. Established in 2006, the foundation aims to make a positive difference in their lives, particularly in Southern and Western Wayne County, Michigan. Grants typically range from $500 to $10,000, often as matching funds, fostering broader fundraising efforts by local nonprofit organizations.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

The Russell Family Foundation Grant, established in 2007 in Duluth, Minnesota, supports charitable causes in the areas of arts, education, environment, health, human services, public benefit, and religion. This private foundation awards grants exclusively to organizations that qualify under Section 501(c)(3) of the Internal Revenue Code, with a focus on those primarily located in Duluth. Their mission emphasizes fostering community welfare through diverse initiatives.

The Pinetop Assistance League (PAL) Grant provides crucial financial support to elderly blues musicians, ensuring their well-being during emergencies. This grant, part of the Pinetop Perkins Foundation's mission, offers assistance for medical expenses, home care, and essential living costs. Eligible applicants must be professional artists aged 50 or older with a household income below $35,000. By addressing these needs, PAL plays a vital role in preserving the legacy and care of blues musicians.

Commodity Supplemental Food Program

1.2 Program Description

The Commodity Supplemental Food Program (CSFP) is a federally funded grant program of the Food and Nutrition Service (FNS), an agency of the United States Department of Agriculture (USDA). The grant is administered through the Minnesota Department of Health in the Supplemental Nutrition Program section of the Child and Family Health division.

CSFP provides a monthly food package of USDA commodity foods to augment the diets of those who are 60 years of age and older, of low income and considered to be at nutritional risk.

Subject to the availability of federal funds, MDH awards grants to qualified local agencies to operate the program in designated geographic service areas within the State.

The National Institutes of Health (NIH) is inviting applications for the Screening, Brief Intervention, and Referral to Treatment or Prevention (SBIRT/P) program. This funding opportunity aims to explore innovative methods for addressing alcohol, tobacco, and other drug use among adults facing health disparities. The initiative seeks research proposals that will implement and evaluate SBIRT/P strategies in collaboration with healthcare and community partners. This approach is crucial for enhancing public health and ensuring effective interventions.

The Wabtec Direct Grant Program focuses on creating sustainable impacts in local communities by funding 501(c)(3) non-profit organizations. Emphasizing education and environmental stewardship, the program supports initiatives that improve literacy, academic outcomes, and workforce readiness. Grants range from $1,000 to $10,000, prioritizing organizations that engage local Wabtec employees in volunteerism. The program promotes equitable access and non-discrimination while ensuring measurable results in funded projects.

The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.

Minnesota Department of Human Services

The Minnesota Department of Human Services (DHS) Mission is driven by collaboration with community and partners – Counties, Tribes, non-profit and for-profit providers – supporting people to thrive in community and live their healthiest and fullest lives. The DHS Vision is that all people in Minnesota have what they need to thrive in community with no disparities.

Request for Proposals for a Grantee to provide integrated, culturally supportive perinatal care to pregnant Black/African American and American Indian Medical Assistance enrollees who are at high risk for adverse birth outcomes

Objective of RFP

The Minnesota Department of Human Services, through its Health Improvement and Benefit Design Division, is soliciting proposals from qualified responders to provide integrated, culturally supportive perinatal care to pregnant Black/African American and or American Indian Medical Assistance enrollees who are at high risk for adverse birth outcomes. Services must be delivered through qualified integrated perinatal care collaboratives as defined in statutes. The anticipated contract term is two (2) years, from July 1, 2026, through June 30, 2028. The State may extend the contract for up to an additional three (3) years in one-year increments, for a total contract term not to exceed five (5) years.

Funding will be distributed through a competitive review process that includes individuals with relevant subject matter expertise, and, when appropriate, community representatives with regional knowledge. If selected, Responder may only incur eligible expenditures when the contract is fully executed, and the grant has reached its effective date.

The Therapeutic Giving program by Johnson & Johnson focuses on funding initiatives that enhance patient access to treatment and advance health equity, particularly in immunology. Eligible nonprofit organizations can apply for support aimed at improving health outcomes through innovative programs. The initiative prioritizes measurable impacts over fundraising activities, emphasizing the importance of addressing healthcare disparities and promoting disease awareness efforts for diseases like rheumatoid arthritis and psoriasis.

RHTP Project ECHO for Maternal and Behavioral Health

The federal Rural Health Transformation Program (RHTP) was created by H.R.1 (Section 71401 of Public Law 119-21) on July 4, 2025. It is a federal initiative to help states support rural communities in improving health care access, quality, and outcomes by transforming the health care delivery ecosystem. The RHTP focuses on promoting innovation, strategic partnerships, infrastructure development, and workforce investment in rural communities. The federal program will grant up to $50 billion to states over five budget periods. 

This RFP seeks proposals from applicants to provide Project Extension for Community Healthcare Outcomes (ECHO) on topics that include but are not limited to

• maternal health (inclusive of maternal mental health) and
• mental/behavioral health for primary care audiences.

Project ECHOs are virtual, case-based learning and mentorship programs provided by organization(s) to build the skills and confidence of rural physicians, nurse practitioners, and physician associates who often serve as the main access point for maternal health and behavioral health care in rural communities.

Applicants are expected to provide 12–24 one-hour long sessions (minimum of one time per month) in at least one of the topic areas. Applicants are welcome to apply to provide both mental health and maternal health series.

Project ECHOs should focus on:

• Providing education and networking for participating rural clinicians and their care teams.
• Providing an open participation model.
• Sharing responsive knowledge that is adaptable to rural community and clinician needs in underserved and hard-to-reach patient populations.
• Maintaining a focus on case-based learning that is specific to rural populations. Participants will learn from expert-led didactic presentations and discuss their own patient cases to gain new skills and implement evidence-based recommendations.

Crisis Response Grant Program

The Crisis Response Grant Program funds local law enforcement agencies and local units of government to maintain or expand crisis response teams in which social workers or mental health providers are sent as first responders when calls for service indicate that an individual is having a mental health crisis.

RFP Part 1: Overview

Program Description

The purpose of this request for proposal is to fund local law enforcement agencies and local governments to start, maintain, or expand crisis response teams in which social workers or mental health professionals serve as first responders when calls for service involve an individual in crisis. Funding may support a range of models including Crisis Intervention Teams (CIT), mobile crisis teams, co-responder models, alternative response teams (ART), and other social worker/mental health-led response approaches that improve safety, reduce unnecessary justice system involvement, and connect individuals to appropriate care.

Minnesota Department of Transportation

In creating the Department of Transportation in 1976, the Legislature determined that MnDOT would be the principal agency to develop, implement, administer, consolidate and coordinate state transportation policies, plans and programs (Minn. Stat. Ch. 174).

MnDOT makes special efforts to consider the social, economic and environmental effects of its decisions and aggressively promotes the efficient use of energy resources for transportation purposes. It also maintains close working relationships with the many public and private individuals, groups and associations involved in transportation.

Greater Minnesota Transportation Alternatives Solicitation

The Transportation Alternatives Solicitation is a competitive grant opportunity for local communities and regional agencies to fund projects for pedestrian and bicycle facilities, historic preservation, Safe Routes to School and more. Minnesota will be soliciting projects for approximately $12.5 million in available grant funding across the state where the total is sub-targeted to the seven area transportation partnerships (ATPs).

Greater Minnesota applicants must submit a letter of intent describing the key components of their project. A regional representative will contact applicants to help review the project proposal and the steps necessary for delivering a federally funded project prior to local communities and regional agencies submitting a full grant application. 

The CIF Capacity Builder Awards by Endeavor Health focus on enhancing community health through strategic investments. With over $38.5 million allocated to local partnerships, these awards aim to address critical areas like healthcare access, food insecurity, and workforce development. Designed for nonprofit organizations, the awards range from $100,000 to $500,000 annually for 1-2 years, fostering long-term community impact and advancing health equity in the service areas.

About

Being deeply connected to the community means more than providing access to excellent healthcare. It means understanding, and investing in, the health needs of our community.

Through our Community Investment Fund (CIF), Endeavor Health has awarded more than $38.5 million to 59 local partnerships dedicated to enhancing community health and wellbeing, advancing health equity and supporting local economic growth. Together, we’re committed to helping everyone in our communities be their best.

Award categories

Through the CIF, we will make meaningful and intentional investments through impact awards and capacity builder awards. These awards are intended to meaningfully advance the health of our community over time towards three bold aspirations through investments in five areas of focus.

We aspire to a future where:

• A person’s zip code does not determine how long they will live
• Hunger and homelessness in our communities are history
• The healthcare workforce is thriving and representative of the communities we serve

To help advance these aspirations, the CIF will invest in the following areas:

• Access to healthcare
• Behavioral health
• Food insecurity
• Housing insecurity
• Workforce development for careers in healthcare

Impact awards

• Designed for 5-year initiatives where organizations come together to drive measurable impact and longer-term change in the communities we serve by improving existing systems and innovation
• Emphasize strategic cross-sector and/or intra-sector partnerships between community-based organizations
• Uplift community members of greatest need
• Directly align with CIF areas of focus and meaningfully contribute to CIF goals
• Award amount: $1 million per year, up to 5 years