Best Operating Grants for Nonprofits in Minnesota

The Wabtec Direct Grant Program focuses on creating sustainable impacts in local communities by funding 501(c)(3) non-profit organizations. Emphasizing education and environmental stewardship, the program supports initiatives that improve literacy, academic outcomes, and workforce readiness. Grants range from $1,000 to $10,000, prioritizing organizations that engage local Wabtec employees in volunteerism. The program promotes equitable access and non-discrimination while ensuring measurable results in funded projects.

The AGRI First Bite Farm to School and Early Care Grant, offered by the Minnesota Department of Agriculture, aims to assist school districts and early childhood education centers in developing local procurement practices. This grant supports projects that emphasize Minnesota-grown foods, including taste tests and increased menu offerings. Applicants can receive $2,500 to $5,000 without a cash match, fostering a strong connection between local agriculture and education.

Minnesota Department of Health

Mission: Protecting, maintaining and improving the health of all Minnesotans.

Vision: The vision of MDH is for health equity in Minnesota, where all communities are thriving and all people have what they need to be healthy.

Rural Health Transformation Program Funding 

The federal Rural Health Transformation Program (RHTP) was created by H.R.1 (Section 71401 of Public Law 119-21) on July 4, 2025. It is a federal initiative to help states support rural communities in improving health care access, quality, and outcomes by transforming the health care delivery ecosystem. The RHTP focuses on promoting innovation, strategic partnerships, infrastructure development, and workforce investment in rural communities. Minnesota has outlined their initiatives online (learn more about Minnesota's Rural Health Transformation Program).

Grant recipients will select activities from broad RHTP initiatives designed to advance the overarching goals of improving health outcomes and access to care for rural Minnesotans, sustainably expanding the rural health care workforce, strengthening partnerships between providers to expand service delivery in rural communities, and stabilizing rural provider financial health through strategic investments. 

Entity Type: Federally Qualified Health Centers (FQHCs)

Estimated Number of Awards: 5

Estimated Maximum Award in Budget Period 1: $1,900,000

Applicants may request up to the maximum award.

Minnesota Department of Human Services

The Minnesota Department of Human Services (DHS) Mission is driven by collaboration with community and partners – Counties, Tribes, non-profit and for-profit providers – supporting people to thrive in community and live their healthiest and fullest lives. The DHS Vision is that all people in Minnesota have what they need to thrive in community with no disparities.

Request for Proposals for a Grantee to provide integrated, culturally supportive perinatal care to pregnant Black/African American and American Indian Medical Assistance enrollees who are at high risk for adverse birth outcomes

Objective of RFP

The Minnesota Department of Human Services, through its Health Improvement and Benefit Design Division, is soliciting proposals from qualified responders to provide integrated, culturally supportive perinatal care to pregnant Black/African American and or American Indian Medical Assistance enrollees who are at high risk for adverse birth outcomes. Services must be delivered through qualified integrated perinatal care collaboratives as defined in statutes. The anticipated contract term is two (2) years, from July 1, 2026, through June 30, 2028. The State may extend the contract for up to an additional three (3) years in one-year increments, for a total contract term not to exceed five (5) years.

Funding will be distributed through a competitive review process that includes individuals with relevant subject matter expertise, and, when appropriate, community representatives with regional knowledge. If selected, Responder may only incur eligible expenditures when the contract is fully executed, and the grant has reached its effective date.

Minnesota Department of Transportation

In creating the Department of Transportation in 1976, the Legislature determined that MnDOT would be the principal agency to develop, implement, administer, consolidate and coordinate state transportation policies, plans and programs (Minn. Stat. Ch. 174).

MnDOT makes special efforts to consider the social, economic and environmental effects of its decisions and aggressively promotes the efficient use of energy resources for transportation purposes. It also maintains close working relationships with the many public and private individuals, groups and associations involved in transportation.

Greater Minnesota Transportation Alternatives Solicitation

The Transportation Alternatives Solicitation is a competitive grant opportunity for local communities and regional agencies to fund projects for pedestrian and bicycle facilities, historic preservation, Safe Routes to School and more. Minnesota will be soliciting projects for approximately $12.5 million in available grant funding across the state where the total is sub-targeted to the seven area transportation partnerships (ATPs).

Greater Minnesota applicants must submit a letter of intent describing the key components of their project. A regional representative will contact applicants to help review the project proposal and the steps necessary for delivering a federally funded project prior to local communities and regional agencies submitting a full grant application. 

The Pinetop Assistance League (PAL) Grant provides crucial financial support to elderly blues musicians, ensuring their well-being during emergencies. This grant, part of the Pinetop Perkins Foundation's mission, offers assistance for medical expenses, home care, and essential living costs. Eligible applicants must be professional artists aged 50 or older with a household income below $35,000. By addressing these needs, PAL plays a vital role in preserving the legacy and care of blues musicians.

The School Based Services Mini Grant, offered by the Minnesota Department of Human Services, aims to enhance mental health services in schools. It targets Minnesota school districts, especially those in rural and tribal areas, providing seed funding to develop sustainable behavioral health infrastructures. This initiative focuses on improving access to care through qualified providers, telehealth capabilities, and Medicaid billing systems, ensuring that all students have the support they need to thrive.

Crisis Response Grant Program

The Crisis Response Grant Program funds local law enforcement agencies and local units of government to maintain or expand crisis response teams in which social workers or mental health providers are sent as first responders when calls for service indicate that an individual is having a mental health crisis.

RFP Part 1: Overview

Program Description

The purpose of this request for proposal is to fund local law enforcement agencies and local governments to start, maintain, or expand crisis response teams in which social workers or mental health professionals serve as first responders when calls for service involve an individual in crisis. Funding may support a range of models including Crisis Intervention Teams (CIT), mobile crisis teams, co-responder models, alternative response teams (ART), and other social worker/mental health-led response approaches that improve safety, reduce unnecessary justice system involvement, and connect individuals to appropriate care.

About Regions

Regions Financial Corporation is a member of the S&P 500 Index and is one of the nation's largest full-service providers of consumer and commercial banking, wealth management and mortgage products and services. Regions serves customers across the South, Midwest and Texas.

Regions Foundation

Regions Foundation supports community investments that positively impact the communities served by Regions Bank. The Foundation engages in a grantmaking program focused on priorities including economic and community development; education and workforce readiness; and financial wellness. The Foundation is a nonprofit 501(c)(3) corporation funded primarily through contributions from Regions Bank.

Matching Gifts Program

Full-time associates and recent retirees (up to 5 years after retirement) of Regions and its affiliated companies can request a Regions Matching Gift to eligible organizations. The recipient organization must be a 501(c) or 170(c) organization located in the Regions footprint (except for accredited educational institutions, which may be located anywhere in the United States) and has a primary mission that clearly fits one of these categories:

• Economic and community development: Supporting economic prosperity through affordable housing, job creation, small-business development, homebuyer education and retention, neighborhood revitalization and stabilization, food security/hunger relief.
• Education and workforce readiness: Supporting career prosperity through student competency and skill building, college and career readiness, educational access and success, credential building and employment and educator training and resources.
• Financial wellness: Supporting financial prosperity through K-12 and college financial education, adult and workforce financial empowerment.
• Arts and culture: Organizations that promote visual or performing arts, historic or science museums, zoos, botanical gardens, libraries, parks or public radio and television.
• Service members and Veterans: Organizations that have a primary mission of supporting U.S. military service members and veterans.
• Individuals with disabilities: Organizations that have a primary mission of supporting individuals with disabilities.

Regions Matching Gifts for Full-Time Associates

Regions supports organizations important to our associates through the Regions Matching Gifts Program. This program, which is open for use for all full-time Regions associates, affiliate associates and recent retirees, allows you to make an even greater difference to your favorite charities by doubling your tax-deductible contributions to these organizations. 

About Regions

Regions Financial Corporation is a member of the S&P 500 Index and is one of the nation's largest full-service providers of consumer and commercial banking, wealth management and mortgage products and services. Regions serves customers across the South, Midwest and Texas.

Regions Foundation

Regions Foundation supports community investments that positively impact the communities served by Regions Bank. The Foundation engages in a grantmaking program focused on priorities including economic and community development; education and workforce readiness; and financial wellness. The Foundation is a nonprofit 501(c)(3) corporation funded primarily through contributions from Regions Bank.

Matching Gifts Program

Full-time associates and recent retirees (up to 5 years after retirement) of Regions and its affiliated companies can request a Regions Matching Gift to eligible organizations. The recipient organization must be a 501(c) or 170(c) organization located in the Regions footprint (except for accredited educational institutions, which may be located anywhere in the United States) and has a primary mission that clearly fits one of these categories:

• Economic and community development: Supporting economic prosperity through affordable housing, job creation, small-business development, homebuyer education and retention, neighborhood revitalization and stabilization, food security/hunger relief.
• Education and workforce readiness: Supporting career prosperity through student competency and skill building, college and career readiness, educational access and success, credential building and employment and educator training and resources.
• Financial wellness: Supporting financial prosperity through K-12 and college financial education, adult and workforce financial empowerment.
• Arts and culture: Organizations that promote visual or performing arts, historic or science museums, zoos, botanical gardens, libraries, parks or public radio and television.
• Service members and Veterans: Organizations that have a primary mission of supporting U.S. military service members and veterans.
• Individuals with disabilities: Organizations that have a primary mission of supporting individuals with disabilities.

Regions Matching Gifts for Recent Retirees

Retirees of Regions and its affiliated companies are eligible for the Matching Gift Program for up to 5 years after retirement (the gift date must be within the first 5 years of retirement). Regions will match donations of $25 or more, up to a total of $1,000 per year per retiree.

The Regions Community Affairs team will contact the organization on your behalf to verify the gift and review eligibility.

Asia-Pacific Network for Global Change Research

The Asia-Pacific region, home to over half the world's population, faces challenges due to its development goals, which strain natural resources, communities, and cultural heritage. These issues are exacerbated by adverse environmental changes. While research has shed light on these problems, it's clear that more challenges lie ahead. The Asia-Pacific Network for Global Change Research (APN) is well-positioned to generate new knowledge and solutions for these evolving global change and sustainability issues by supporting collaborative research and scientific capacity development activities, particularly those aimed at training the next generation of early career professionals.

APN 2025 Call for Proposals: CRRP 

Through the competitive Collaborative Regional Research Programme (CRRP), we promote regional research that has potential to improve our understanding of global change and its implications while contributing to a sound scientific basis for policymaking in areas affected by global change. Under this pillar, APN supports collaborative research that contributes to the evolving science-policy arena, including the UNFCCC Paris Agreement, IPCC, IPBES, post-2015 Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction and the UN Decade of Ocean Science as well as ongoing and new global change and sustainability research programmes.

Activities of interest under the CRRP Programme

APN promotes regional collaborative research that improves understanding of the physical, biological and human dimensions of change in the Earth system and advances actionable science that informs decision-making. APN accepts proposals that engage at least 3 member/approved countries in the region, and prioritise collaboratively designed, actionable research with non-academic stakeholders. Proposals must address one or more of the following activities:

• Collaborative research on global change and sustainability that particularly addresses GAPS, ANALYSIS, SYNTHESIS and ASSESSMENT work.
• Collaborative research that develops PATHWAYS and MECHANISMS to achieve sustainable development, and develop adaptation strategies.
• Collaborative PLACE-BASED INTEGRATIVE RESEARCH, particularly from developing countries.
• Collaborative research that is CO-DESIGNED to contribute to the Paris Agreeemnt, Sustainable Development Goals, Sendai Framework for Disaster Risk Reduction, Post-2020 Global Biodiversity Framework, UN Decade of Ocean Science (2021-2030), and the accumulation of scientific knowledge at IPCC, IPBES, etc.

The Laura Jane Musser Fund was established by the estate of Laura Jane Musser of Little Falls, Minnesota to continue the personal philanthropy, which she practiced in her lifetime.

Environmental Initiative Program

The Laura Jane Musser Fund assists public or not-for-profit entities to initiate or implement projects that enhance the ecological integrity of publicly owned open spaces, while encouraging compatible human activities. The Fund’s goal is to promote public use of open space that improves a community’s quality of life and public health, while also ensuring the protection of healthy, viable and sustainable ecosystems by protecting or restoring habitat for a diversity of plant and animal species.

Projects must..

• Focus on protecting/restoring a sustainable ecosystem that is a defined, public open space.
• Promote public access to and use of the defined open space.
• Involve active participation of local community members, with a particular appreciation for volunteer and youth engagement and stakeholder contributions.
• Contain measurable outcomes within the first 12-18 months.
• Include a plan for the long term financial and environmental sustainability of the proposed program.

Projects during any one grant period will be eligible for either:

• implementation grants or 
• planning grants

Environmental Initiative - Implementation Grant Program

Implementation grant applications must demonstrate clear evidence of local community active participation and support.

Projects will be eligible for either planning or implementation funds during any one grant period.

Arbor Rising Grant, established in 2010, is a NYC-based nonprofit providing unrestricted multi-year funding and capacity-building support to nonprofits focused on alleviating poverty. The grant process occurs every three years, with the next round in 2025 being invitation-only. Eligible organizations must demonstrate high potential and effective leadership, typically operating on a modest budget. Arbor Rising prioritizes applicants from the NYC metro area while expanding to cover the lower 48 US states.

The National Institutes of Health (NIH) is inviting applications for the Screening, Brief Intervention, and Referral to Treatment or Prevention (SBIRT/P) program. This funding opportunity aims to explore innovative methods for addressing alcohol, tobacco, and other drug use among adults facing health disparities. The initiative seeks research proposals that will implement and evaluate SBIRT/P strategies in collaboration with healthcare and community partners. This approach is crucial for enhancing public health and ensuring effective interventions.

The Drive for 5 Initiative - Job Placement Services Competitive Grant, offered by the Minnesota Department of Employment and Economic Development (DEED), aims to enhance employment opportunities for adults facing barriers. This grant focuses on providing workforce development services, work-based learning, and job placement support in sectors such as technology, labor, and manufacturing. By addressing educational and economic disparities, the initiative seeks to foster long-term, family-sustaining employment for Minnesotans.

The Lloyd K. Johnson Foundation offers grants over $3,500 to nonprofits and public entities aiming to enhance community welfare, arts, education, economic development, and environmental stewardship. Operating since 1975, the foundation prioritizes projects that benefit residents in Cook, Lake, and Southern St. Louis Counties. Eligible applicants must have a 501(c)(3) designation or work with a fiscal sponsor. The foundation does not fund private foundations or projects for election campaigns or direct religious purposes.

The Health Care Workplace Safety Grant program, established by Minnesota's 2023 Session Law, aims to enhance safety in health care environments by funding initiatives that train staff in de-escalation and support services. With a total of $1.5 million available through 30 grants, each grant may provide up to $50,000 to improve workplace safety and prevent violence, ensuring a secure atmosphere for both staff and patients.

The Festivals Grant, offered by the Minnesota Humanities Center, aims to support cultural festivals and events across Minnesota. With funding of $1.5 million available for each of the fiscal years 2026 and 2027, eligible organizations can apply for grants to enhance community engagement through arts programming, staffing, and logistics. Applicants may seek up to $200,000 per year, fostering cultural connections and celebrating local traditions.

Minnesota Department of Health

Mission: Protecting, maintaining and improving the health of all Minnesotans.

Vision: The vision of MDH is for health equity in Minnesota, where all communities are thriving and all people have what they need to be healthy.

Rural Health Transformation Program Funding 

The federal Rural Health Transformation Program (RHTP) was created by H.R.1 (Section 71401 of Public Law 119-21) on July 4, 2025. It is a federal initiative to help states support rural communities in improving health care access, quality, and outcomes by transforming the health care delivery ecosystem. The RHTP focuses on promoting innovation, strategic partnerships, infrastructure development, and workforce investment in rural communities. Minnesota has outlined their initiatives online (learn more about Minnesota's Rural Health Transformation Program).

Grant recipients will select activities from broad RHTP initiatives designed to advance the overarching goals of improving health outcomes and access to care for rural Minnesotans, sustainably expanding the rural health care workforce, strengthening partnerships between providers to expand service delivery in rural communities, and stabilizing rural provider financial health through strategic investments. 

Entity Type: Tribal Nations (Bois Forte Band of Chippewa; Fond du Lac Band of Lake Superior Chippewa; Grand Portage Band of Lake Superior Chippewa; Leech Lake Band of Ojibwe; Lower Sioux Indian Community; Mille Lacs Band of Ojibwe; Oyate (Upper Sioux); Prairie Island Indian Community; Red Lake Nation; White Earth Nation)

Estimated Number of Awards: 10

Estimated Maximum Award in Budget Period 1: $150,000 - $807,996

Applicants may request up to the maximum award.

The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.

Minnesota Historical Society

The Minnesota Historical Society preserves Minnesota's past, shares our state's stories and connects people with history in meaningful ways, for today and for tomorrow. Because history matters!

We're part of Minnesota's rich history. Since 1849, we've grown to become one of the largest and most prestigious historical societies in the country. We play an important role in our state's historic preservation, education and tourism; and provide the public with award-winning programs, exhibitions and events.

We owe it to future generations to be good stewards of the past.

Native American Museum Fellowship

The Native American Museum Fellowship (NAMF) Program is a ten-week paid fellowship that will introduce Native community members to the museum field through three weeks of seminar and workshops and seven weeks of an MNHS internship program. These ten weeks are designed to engage and expose fellows to relevant cultural resources within MNHS and partnership sites, the broader public history of Minnesota and neighboring states, and professional opportunities within the museum field– ranging from Tribal historic preservation to exhibit curation. Fellows will learn about career paths and the various requirements for working in museum spaces, both on and off of reservation lands, as well as the particular challenges faced by Native American communities in terms of preserving tribal history and disturbing the institutionalized historical narratives of who Native people were and are.

The first three weeks of the program will be an in-depth seminar that will focus on the function of museums, cultural resources, public history, and tribal historic preservation fields. Through a mix of readings, podcasts, videos, discussions, exhibit analyses and guest speakers, fellows will come to have a better understanding of the day-to-day workings of museums and historic sites, and the values and practices that inform these institutions. The cohort will travel often to MNHS partnering sites and will have the opportunity to visit various Native organizations in or around the Twin Cities. Fellows will be placed within the Minnesota Historical Society network for the remainder of the fellowship where they will complete a hands-on internship experience of their choice.

Participants in the program will receive a living expense stipend for the duration of the program as well as travel expense reimbursement, a stipend pending completion of the seminar portion of the program, and a paid internship for the remaining seven weeks.

Topics covered

• Collections
• Conservation
• Tribal and Institutional Partnerships
• Tribal Historic Preservation
• Cultural Resource Stewardship
• Exhibitions
• ​Archaeology/NAGPRA
• Section 106
• And more!

Program Requirements

NAMF is designed as a ten week hybrid program with a home base of the Minnesota History Center, located in St. Paul. The 3-week seminar portion of the program has mandatory in-person attendance to receive the full stipend. A 20-hour per week paid internship could be all in-person or hybrid, depending on the internship supervisor. Travel to historic sites and communities will be required throughout the program period with travel arranged through program staff. 

Please Note: Fellows are expected to find their own housing upon accepting their letter of admittance. Mileage accumulated from out-of-town trips and lodging used during seminar will be reimbursed (within reason) to eliminate financial barriers during your time as a NAMF fellow. 

The Green Fertilizer Program Grant in Minnesota offers approximately $3.8 million to agricultural and rural electric cooperatives for investments in green fertilizer production facilities. Eligible projects must utilize renewable energy and green hydrogen, with a minimum grant award of $250,000. The program emphasizes strong business readiness and requires matching funds from cooperatives. Successful applicants must be licensed, in good standing, and committed to sustainable practices for fertilizer production, ensuring environmental responsibility in the agricultural sector.

The Health Information Outreach Award, funded by the National Library of Medicine, aims to enhance access to essential health information for underrepresented populations and healthcare professionals. This initiative focuses on improving health literacy and equity through diverse projects, including training, technology access, and community outreach. Eligible organizations from select Midwestern states can apply, prioritizing innovative solutions that address health disparities and promote informed health decisions among vulnerable communities.

The La Crescent Community Foundation, established in 1995, aims to enhance the quality of life in the La Crescent area through targeted grants. It supports various community projects, including park improvements and educational initiatives, while prioritizing organizations that uphold non-discrimination policies. The Foundation's grants focus on local needs, with a preference for applications from schools and local government agencies. Recent efforts include funding for a new event center, demonstrating a commitment to community development.

The James M. Cox Foundation Grant offers support to nonprofit organizations focused on conservation, early childhood education, family empowerment, and health. Organizations must be 501(c)(3) tax-exempt and located in areas where Cox Enterprises operates. Grant applications are accepted year-round, with deadlines before Trustee meetings. Preference is given to organizations with a history of local engagement. This foundation embodies the philanthropic spirit of its founder, James M. Cox, by giving back to the community.

SC Johnson Grants aim to enhance community welfare through charitable contributions, focusing on health, sustainability, and opportunity. Since 1937, the company has committed five percent of its pretax profits to support registered charities and nonprofit organizations, especially in areas where it operates. The grant program prioritizes initiatives addressing healthcare access, environmental conservation, and educational equity, ensuring that efforts align with the values of community service and corporate responsibility.

The Conservation Connect Fellowship Program, offered by the National Forest Foundation, invites graduate students to engage in hands-on conservation projects. This fellowship provides practical experience, mentorship from conservation professionals, and training in collaborative leadership. Fellows will gain a deep understanding of forest management and expand their professional networks. With a focus on developing future conservation leaders, the program seeks students passionate about public lands and community engagement.