Best Large Grants for Nonprofit Organizations in Missouri

The Tommy Wilson Memorial Grant, established by Dr. George T. Wilson and his wife Irene, honors their son Tommy, who had cerebral palsy. This grant supports recreational programs for individuals with disabilities and aims to positively impact their lives. Applicants must be nonprofit organizations with a successful history of programming for individuals with disabilities. The grant prioritizes programs serving economically disadvantaged individuals and may only fund applicants once every five years.

American Physical Society

The American Physical Society is a nonprofit membership organization working to advance physics by fostering a vibrant, inclusive, and global community dedicated to science and society. APS represents more than 50,000 members, including physicists in academia, national laboratories, and industry in the United States and around the world.

APS Honors recognizes and celebrates the accomplishments of the global physics community. Guided by our core values, APS Honors encourages nominations that reflect the full range of talent, distinction, and experience in our field, and supports broad canvassing for professional achievement across diverse backgrounds, perspectives, and expertise.

Joseph A. Burton Forum Award

The Joseph A. Burton Forum Award recognizes outstanding contributions to the public understanding or resolution of issues involving the interface of physics and society. The award consists of $5,000, a certificate citing the contributions of the recipient, and an allowance for travel to the meeting of the Society at which the award is presented. It will be awarded annually.

Nominations will be considered for three review cycles provided the nominator re-certifies the nomination before the next deadline.

The Lenora Jane Perdue Scholarship, offered by the North East Community Foundation, supports graduating seniors from Westfield Academy, Ripley Central School, and North East High School pursuing a degree in education. Applicants must maintain a GPA of 3.0 or higher. This scholarship aims to encourage and assist students dedicated to a career in teaching, fostering the next generation of educators in their community.

The Sharing Language Diversity Fellowship supports Ph.D. students engaged in Indigenous language documentation and data archiving. Funded by the Endangered Language Fund, it encourages sustainable public sharing of linguistic materials, aiming for equitable access to research. With grants up to $30,000, recipients must publicly archive documentation materials within three years, ensuring compliance with community wishes and best practices. This initiative fosters a culture of Open Access in linguistics, benefiting both scholars and Indigenous communities.

The Patterson Family Foundation's Innovation in Education Grant aims to enhance educational opportunities in rural communities. With a focus on creative proposals that foster new ideas for sustainable growth, the foundation invites eligible organizations in Kansas and western Missouri to apply. Registration is required before submitting a Letter of Intent, with specific deadlines for each funding round. This initiative underscores the foundation's commitment to supporting initiatives that empower local communities and promote long-term benefits.

The Kazanjian Economics Foundation Grant focuses on enhancing economic literacy across various educational settings. With a history of over 70 years, the foundation supports projects that deliver economic education to youth, particularly in non-school environments. It emphasizes teacher training and initiatives for underserved communities, while also promoting behavioral economics and entrepreneurship. The foundation welcomes letters of interest year-round, with recommended deadlines of March 10th and September 10th for grant cycles.

The Amy Clampitt Poet Residency Program, established by The Berkshire Taconic Community Foundation, offers a six-month residency for poets at Amy Clampitt's former home in Lenox, Massachusetts. This program aims to foster the study and promotion of poetry, providing a peaceful retreat for a poet to focus on their craft. Selected poets receive a monthly stipend of $4,000 and are encouraged to make their creative work a priority during their stay.

The Chan Zuckerberg Initiative is calling for transformative research proposals through the Advancing Technologies for Spatiotemporal Omics in Live Tissue program. This initiative seeks to combine innovative engineering with biological research to explore the complex molecular dynamics of health and disease. By fostering collaboration among scientists and AI experts, this funding aims to unlock new high-precision interventions, significantly advancing our understanding and management of health issues.

The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.

Scholarships are available to graduating high school seniors. Applications are accepted from mid-November until mid-March. Scholarship award recipients will be announced at the high school awards ceremony. 

Beatrice Reynolds Memorial Scholarship

Established by the late Ira T. Reynolds in memory of his late wife to assist a Susquehanna Community School District graduate who will major in education or teacher training. Scholarship is provided in four equal installments as long as the recipient remains a student in good standing.

The Guru Krupa Foundation Grant supports charitable causes in social, educational, and religious/cultural areas, rooted in Hindu values. The foundation prioritizes projects that aid the underprivileged, enhance education, and preserve cultural heritage, particularly in India and the US. Eligible organizations must be tax-exempt and demonstrate a commitment to effective accounting practices. The foundation seeks specific projects with measurable outcomes, focusing on direct funding for programs rather than administrative costs.

Seattle Foundation

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Theresa Earenfight Scholarship

The purpose of the Theresa Earenfight Scholarship is to support undergrad or graduate students who are passionate about the intersection of social justice and animal welfare within a historical context. Applicants should be studying history, in particular how history intersects with animal activism, animal rights, animal liberation, and other related topics. Preference will be given to students with strong financial need, students of color and those from historically marginalized communities, and/or students who may face barriers to receiving other scholarships. This is a $10,000 annual scholarship renewable through the completion of the student’s degree, assuming the student continues to meet the eligibility criteria. The scholarship may be applied to tuition and fees, or other academic expenses payable to the college or university.

The American Australian Association's Graduate Education Fund offers scholarships for American and Australian students pursuing Masters, Ph.D., or Postdoctoral research in various fields, including Science, Technology, and Sustainability. Established in 2002, the fund has awarded nearly $11 million to over 350 scholars. Scholarships up to $40,000 support travel, living, and tuition costs. Applications are accepted biannually, with specific periods for each direction of study. It also includes scholarships for Indigenous students.

The AOAP Life Jacket Grant supports aquatic facilities in drowning prevention by offering funds for swim lessons and life jackets. Administered by the Association of Aquatic Professionals, the program aims to provide at least 100 free lessons and distribute 500 life jackets annually. This initiative promotes safety education and awareness of life jacket usage, ensuring that underserved communities have access to vital water safety resources. Applications are open to AOAP members meeting eligibility criteria.

The Capacity Accelerator for Tribal Offshore Wind Engagement, launched by the U.S. Department of Energy, aims to empower Tribal Nations in offshore wind energy decision-making. This initiative offers up to $7.1 million in cash prizes and technical assistance through three phases: Capacity Needs, Capacity Development, and Engagement. Each phase is designed to support Tribes in outlining their priorities, building capacity, and implementing impactful projects in offshore wind energy.

The Congressional Science Fellowship Program offers a unique opportunity for Ph.D. holders to work at the intersection of science and government in Washington D.C. This prestigious fellowship, sponsored by ASA, CSSA, and SSSA, allows participants to apply their expertise as special assistants to Congress members. The fellowship begins in September 2025 and concludes in August 2026, providing an annual stipend and relocation expenses. Ideal for early to mid-career scientists, it encourages the use of scientific knowledge in public policy.

The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.

The GHI Doctoral and Postdoctoral Research Fellowships offer support for European and North American scholars pursuing research in German and European history, German-American relations, and North American history. Awarded by the German Historical Institute, these fellowships prioritize projects requiring primary sources in North America and are available for one to four months. Monthly stipends are € 2,000 for doctoral students and € 3,400 for postdoctoral scholars, with additional airfare reimbursement for European recipients.

The AOAP Swim Lesson Grant aims to enhance drowning prevention by providing financial support to aquatic facilities for swim lessons and life jackets. With a minimum allocation of $10,000 annually, the program seeks to offer at least 100 free lessons to low-income participants and distribute 500 life jackets each year. It encourages non-profit organizations to apply, ensuring a focus on education and safety in aquatic environments. This grant represents a significant step towards making swimming accessible and safe for all.

Our Mission

KidsGardening creates opportunities for kids to play, learn, and grow through gardening, engaging their natural curiosity and wonder.

We want every child to experience the unique transformation that occurs when they spend time caring for a garden, be it outside, in a classroom, or in a cup on the kitchen windowsill. Since 1982, KidsGardening has served as a premier support provider for youth garden programs nationwide.

We support educators and families with grant funding, original educational resources, inspiration, and community to get more kids learning through the garden.

Growing the Future Intergenerational Garden Grant

In celebration of Miracle-Gro’s 75th anniversary, Miracle-Gro and KidsGardening are partnering to fund 75 intergenerational youth garden grants in 2026.

Intergenerational gardens provide opportunities for older gardeners to pass along traditions, knowledge, and skills to the next generation or share the experience of developing skills if new to gardening. In turn, young people bring their curiosity, wonder, and contagious enthusiasm for learning and life, exciting everyone involved in the growing process.

The 2026 Growing the Future Intergenerational Garden Grant is designed to support gardens that intentionally bring children and older adults together through shared gardening experiences.

Funding Priorities

The selection of winners is prioritized based on demonstrated need and program impact. KidsGardening considers a variety of factors when determining needs, including:

• Socioeconomic & Sociodemographic Factors: How does the program exist within or engage a community that has been systematically denied resources, whether physical assets and money or representative leadership and community services? Organizations affected by multiple socioeconomic and sociodemographic factors are given priority.

• Program Funding and Support: Does an organization have access to consistent, substantial monetary support or prior grant funding? Or are pre-existing resources (financial or otherwise) limited? Organizations experiencing the latter are given priority.

• Impact: Will grant funding dramatically expand learning opportunities for program participants? Does the intended impact reflect the needs of the community? Organizations working with more than 50 youth will be given priority.

Award Packages

Grantees will receive:

• A $500 cash award check
• A $250 coupon to purchase essential gardening supplies from ScottsMiracleGro.com

The Wilbur Awards, presented annually since 1949 by the Religion Communicators Council, celebrate excellence in communicating religious values and themes in secular media. Open to individuals and organizations, entries must have been published or broadcast in 2024. Categories include audio, audio-visual, images, and written works, allowing for both English and non-English submissions. The awards emphasize professionalism and respect in highlighting uplifting religious narratives within diverse media platforms.

The Presbyterian Committee on the Self-Development of People Grant supports partnerships with economically disadvantaged groups in the U.S. It aims to empower these communities to take control of their lives and address systemic issues of poverty and oppression. This initiative encourages sustainable change through community-led programs that advocate for justice, human dignity, and economic equity, fostering a transformative impact on their local environments.

The National Cancer Institute (NCI) invites applications for transformative research in cancer biology and oncology through nanotechnology. This funding opportunity aims to address significant challenges by exploring the interactions of nanomaterials with biological systems. Projects should focus on utilizing nanoparticles and devices for targeted cancer therapies and enhancing diagnostic capabilities. Successful proposals will contribute to the foundational knowledge necessary for future nanotechnology-based interventions in cancer treatment.

About

Originally conceived by Dr Bruce Mesara in 1990 as a means to carry on his philanthropic efforts beyond his lifetime, the Mesara Family Foundation was re-envisioned by his two children Amy and Douglas in 2014, and received their 501(c)(3) status from the IRS in 2015. Amy and Douglas sought out the assistance of their cousins to build upon the charitable principals on their parents, aunts and uncles.

The foundation is headquartered in Kalamazoo Michigan.

Mission

The mission of the Mesara Family Foundation is to honor the philanthropic principles of the Mesara and Pauch families by supporting carefully selected organizations that share similar values. Our focus is to provide support toward education, conservation and other causes of special family interest where our funding will make a genuine difference.

The Bonnie Plants 3rd Grade Cabbage Grant Program inspires young students to cultivate a love for gardening by providing free oversized cabbage plants to 3rd grade classrooms across the continental U.S. Initiated in 1996, the program encourages hands-on learning about where food comes from. Each year, students compete for a $1,000 prize awarded to the best cabbage grown, fostering excitement and education about agriculture. This initiative not only promotes environmental awareness but also engages students in practical science.

The BRAIN Initiative aims to advance innovative neurotechnologies by funding early-stage clinical studies for devices that record or stimulate the human central nervous system. This initiative encourages collaborations between clinical researchers and device manufacturers to facilitate groundbreaking studies. By addressing the challenges of obtaining safety and utility data, this program supports both non-invasive and significant risk devices, providing essential insights into their functionality and design. Applications are currently not being solicited, allowing time for meaningful project development.

The Camille Dreyfus Teacher-Scholar Awards Program supports talented early career faculty in the chemical sciences by providing an unrestricted research grant of $100,000. Nominees must demonstrate outstanding research achievements and a commitment to education. Each institution can submit one nomination annually. The program emphasizes innovation and leadership in research while considering factors such as awards, publication success, and contributions to education, particularly at the undergraduate level.