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Best Large Grants for Nonprofit Organizations in Missouri

Find the perfect Large Grants for Nonprofit Organizations in Missouri on Instrumentl. 10,000+ Large Grants for Nonprofit Organizations in Missouri in the United States.

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$2.59B

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$5K

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10,000+ grants
$2.59B total
$5K median

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Freeman Fellowship

American Society Of Civil Engineers Inc
Private
United States
Unspecified amount
The Freeman Fellowship, established by the American Society of Civil Engineers in 1924, supports young engineers pursuing graduate studies in hydraulic engineering. Awarded annually to up to three deserving students, it covers tuition, research, and living expenses. This fellowship encourages the next generation of civil engineers to excel in their education and contributes to the advancement of the field, reflecting ASCE's commitment to fostering talent within the profession.
Education - Higher Education Civil Engineering

SPRK-ing Interest in Computer Science

American Indian Science and Engineering Society (AISES)
Association/Society
American Samoa, Guam +6 more
Unspecified amount in in-kind support
The AISES SPRK-ing Interest in Computer Science program engages Indigenous K-12 students through fun coding and robotics activities. By utilizing Sphero BOLT and Indi robots, students gain hands-on experience in STEM and computer science, fostering greater interest and competency in these fields. Participating schools receive essential materials and training, promoting a culturally relevant learning experience. Priority is given to middle schools, encouraging greater participation in STEM+CS education among Native students.
Computer Science & Engineering STEM / STEAM Education

Bengier Foundation Grants

Bengier Foundation
Private
United States
Unspecified amount

Bengier Foundation

After lots of hard work and more than a bit of luck, Gary and Cynthia were able to retire from professional business careers at an early age. They decided then to try to give back a little to their community and to others less lucky than they. So the Bengier Foundation was formed in 2004 to give a helping hand to bright, hardworking young people who need a little help to find their own success.

One of our goals is to help – in a small way – to focus attention on the need to increase our American educational capital. The dropout rate statistics are shocking. We must do more to help the next generation prepare for the increasing demands of our ever-more sophisticated information economy. The Bengier Foundation believes that we must give everyone a chance to achieve their potential.

Bengier Foundation Grants

The foundation's mission is to provide educational experiences that motivate, broaden and qualify bright, hard working young people who have limited means and limited opportunities to enlarge their expectations of what they can accomplish in life.

  • By motivate we mean to change a young person’s expectations about themself, by providing experiences which pique their interest, or that let them see themself in a role or career that they never previously imagined.
  • By broaden we mean to allow a young person to have experiences that broaden their perspective of the world or cause them to view it and their role in it differently.
  • By qualify we mean to help a young person gain the experiences and education that will allow them to succeed in college and in life.
Education Academic Success & Enrichment

NewSchools: Learning Solutions Grant Program

NewSchools Venture Fund
Private
United States
US $150,000 - US $250,000
The NewSchools: Learning Solutions Grant Program aims to empower K-8 students by enhancing their literacy and numeracy skills, crucial for overcoming educational challenges exacerbated by the pandemic. With a focus on innovative learning solutions, the program seeks to fund early-stage ideas that engage students and support educators. By leveraging research and technology, including generative AI, it aims to create equitable educational opportunities, fostering a brighter future for all students.
Education - K through 12 Technology Access & Digital Literacy

Academic Career Excellence (ACE) Award (K32 Independent Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Academic Career Excellence (ACE) Award (K32) supports early-stage postdoctoral scholars through rigorous research and career development over three years. Applicants must submit their proposals up to a year before or two years after starting their postdoctoral positions. This award emphasizes innovative research ideas and strategic planning for training and mentorship, aiming to cultivate independent investigators in research fields aligned with the missions of NIH Institutes and Centers.
Education - Higher Education Health & Medicine

Elaine R. “Boots” Fisher Award

Foundation Of The Federal Bar Association
Private
United States
US $1,000

Foundation of the Federal Bar Association

The Foundation of the Federal Bar Association provides the best way for practitioners to give back to the Federal legal community. Chartered by Congress in 1954, the Foundation serves people in communities across the United States through its generous grants, scholarships, and programming.

Our Mission: The Foundation’s mission is to:

  • Promote and support legal research and education;
  • Advance the science of jurisprudence;
  • Facilitate the administration of justice;
  • Foster improvements in the practice of Federal law

Elaine R. “Boots” Fisher Award

Elaine R. “Boots” Fisher was the wife of former National and Northern District of Ohio Chapter President Stanley M. Fisher. Sadly, in 1989 “Boots” Fisher succumbed to illness. The Elaine R. “Boots” Fisher Award is presented as a memorial to the outstanding and unselfish contributions made by “Boots” Fisher to improve the quality of life and opportunities of all persons. She gave of herself willingly to help others to overcome adversity.

The award is intended to stimulate, encourage and recognize exemplary community, public and charitable service by members of the Federal Bar Association. Nominations should demonstrate:

  • Continuous general or specific contributions to community, charitable or public service;
  • Specific accomplishments for which the nominee is primarily responsible which serve to enhance, promote and encourage community, charitable and/or public service; and
  • Specific personal achievements of the nominee which serve to provide inspiration and hope to others. The charitable contribution made in the name of the recipient reflects the essence of the person in whose honor this award is established.

The charitable contribution made in the name of the recipient reflects the essence of the person in whose honor this award is established. A cash contribution in the amount of $1,000 will be made in the recipient’s name to a charity selected by the recipient. The charity selected must meet the requirements of Section 501(c)(3) of the Internal Revenue Code and contributions to charitable organizations which promote the provision of legal services and the administration of justice are encouraged but not required.

Legal Services Law Community Services

THS Patricia Roppel Memorial Scholarship Fund

The Alaska Community Foundation
Private
United States
US $5,000

The Alaska Community Foundation

The Alaska Community Foundation connects people who care to the causes that make a difference and matter most to them. We encourage and nurture philanthropy through building and managing permanent endowments, convening stakeholders, working with partners to strengthen Alaskan communities, and providing donors with flexible giving options that are strategic to their philanthropic objectives.

Scholarships at ACF

Each year, more than 60 scholarships are available to Alaska students—and it all starts with one simple application. With one login and one application, you’ll be considered for every scholarship you may be eligible for. Whether you’re taking your first step toward college, training for a career, or continuing your education, these scholarships are here to help carry you forward, backed by donors who believe in Alaska’s students and the futures they’re building. 

THS Patricia Roppel Memorial Scholarship Fund

The THS Patricia Roppel Memorial Scholarship is a $5,000 award made annually to an undergraduate or graduate student who is either enrolled or intends to enroll at an accredited college and majoring in history, pursuing the study of Alaska. 

The Tongass Historical Society is a private, non-profit corporation whose purpose is to discover, preserve, and disseminate knowledge of the history of Ketchikan and Southeast Alaska for present and future generations. Established in 1961, the Society brings together people of all ages who share an interest in Ketchikan’s rich and colorful heritage. The Tongass Historical Society is actively pursuing the preservation of the information and items intimate with our unique part of Alaska.

This scholarship is in memory of Patricia “Pat” Roppel– author, historian, and Alaskan. Pat moved to Alaska in 1959, where she and her husband Frank grew to love Southeastern Alaska. Her numerous published works about Southeast Alaska spanned various topics ranging from business to salmon hatcheries in the area.

Pat is remembered as someone who was open and loved to share her love and knowledge with others. Her legacy is remembered in the awarding of this scholarship.

Education - Higher Education History

ASPCA Right Horse Grants to Amplify Adoptions and Support Community Equines

American Society for the Prevention of Cruelty to Animals (ASPCA)
Private
United States
US $5,000 - US $50,000
The ASPCA Right Horse Grants aim to enhance equine adoptions and support community equines by funding programs that boost shelter capacity or assist in keeping owned equines in their homes. Grants between $5,000 and $50,000 are available, with a total funding pool of up to $750,000. Eligible applicants include ASPCA Right Horse Adoption Partners and organizations committed to the welfare of retired Thoroughbred racehorses. Proposals should clearly outline the objectives and expected impacts.
Animal Welfare - General Animal Welfare - Domestic Animals & Pets

National Home Library Foundation Grant

National Home Library Foundation
Private
United States
US $500 - US $5,000
The National Home Library Foundation Grant supports nonprofits in distributing books and reading materials to libraries and community groups with limited resources. This initiative aims to promote literacy and combat illiteracy among all ages through various programs. Grants are available only to tax-exempt organizations that adhere to non-discrimination policies. Preference is given to requests from the Washington DC, Maryland, and Virginia areas, with applications considered on a rolling basis.
Library Services Literacy

Peterson Foundation Grant

Hal And Charlie Peterson Foundation And Fd Mgmt Trust
Private
United States
Unspecified amount
The Peterson Foundation Grant, established in 1944 by Hal and Charlie Peterson, supports charitable organizations within Kerr, Bandera, Edwards, Gillespie, Kendall, Kimble, and Real Counties. The Foundation primarily funds health care and education initiatives, and applications are accepted year-round from §501(c)(3) organizations in the service area. Notably, grants are not available for religious purposes, political actions, or individuals, ensuring a focus on community enrichment.
Health Care Access & Delivery Education

Limited Competition: Small Grant Program for ORIP Special Emphasis Research Career Award (SERCA) K01 Recipients (R03 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The Limited Competition Small Grant Program for ORIP SERCA K01 Recipients provides funding to early-stage veterinary scientists to enhance their research capabilities and transition to independent investigator status. This initiative addresses challenges faced by these researchers, including reliance on funding from senior investigators. Grants support pilot studies, secondary data analysis, and development of research methodologies, aiming to foster independence within a two-year timeframe without funding clinical trials.
Veterinary Science & Services Biology

GroMoreGood Grassroots Grant Program

Scotts Miracle-Gro Foundation
Corporate
United States
US $750 - US $1,500
The Scotts Miracle-Gro Foundation and KidsGardening offer the GroMoreGood Grassroots Grant to enhance community gardens across the U.S. This initiative supports programs that engage under-resourced communities, focusing on youth participation. In 2026, 120 grants of $750 will be awarded, with additional funding opportunities available through specialty awards for programs addressing specific needs, including those serving LGBTQ+ youth and communities of color.
Horticulture & Gardening Greening & Beautification

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses

American Society for the Prevention of Cruelty to Animals (ASPCA)
Private
United States
US $10,000 - US $40,000

ASPCA Reimagining Racers: Grants for Adopting Out Retired Racehorses Grant

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and organizations actively participating in the warm-up ring (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) are invited to apply for a grant to support an increase in capacity and/or efficiency of programs aimed at adopting out retired Thoroughbred racehorses. 

Funding requests for this grant initiative should focus on:

Activities that increase capacity, decrease length of stay, reduce cost of care or increase efficiencies, and/or improve humane outcomes in other ways. Examples:

  • Training programs
  • Programs that engage new adopters and grow the market share for adoption
  • Medical make-ready or rehabilitation with a focus on innovation and/or sustainability
  • Collaborations with other equine industry organizations to increase support for retired racehorses

Proposals will be evaluated on their potential (within the 12-month grant term) to: 

  • Increase capacity (the number of horses that can be rehabilitated, trained, and placed)
  • Decrease length of stay
  • Decrease cost of care
  • Reduce risk, harm or suffering for retired racehorses

Requests may be for the creation of new programs or the expansion of existing programs. Programs that test innovative ideas are welcome.

Grant Amounts

Grants will generally range from $10,000-$40,000, with a maximum individual grant amount of $60,000. The total funding amount available for this grant opportunity is $200,000. 

Eligibility

ASPCA Right Horse Adoption Partners, ASPCA Right Horse Industry Partners, and active Warm-Up Ring participants (defined as groups that are actively working to achieve the 13 criteria for Partnership and are participating on myrighthorse.org) whose mission or operations focus significantly on serving retired Thoroughbred racehorses are eligible to apply for this grant opportunity. Adoption organizations must be up to date on reporting data biannually to the Equine Welfare Data Collective (EWDC). If you’re unsure about your eligibility, you may contact therighthorse@aspca.org to confirm before applying.   

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) was founded on the belief that animals are entitled to kind and respectful treatment by humans. We invite all voices to join us in working together to improve the lives of animals in need.

Animal Welfare - General Animal Welfare - Domestic Animals & Pets

Peggy Barber Tribute Grant

American Library Association (ALA)
Association/Society
American Samoa, Guam +4 more
US $2,500
The Peggy Barber Tribute Grant, offered by the American Library Association, supports libraries facing budget constraints by providing $2,500 to three selected libraries. The 2025-2026 cycle focuses on programming that strengthens community ties through libraries as third spaces, promoting gatherings and connections among individuals. Eligible proposals may include intergenerational gardening programs, play-based activities for adults, or visual arts performances. Applicants must have ALA or ARSL membership and demonstrate how their program will foster community engagement.
Library Services Civic Engagement & Education

Vern Chesbro Memorial Scholarship Fund

Greater Kansas City Community Foundation
Private
United States
Unspecified amount

Vern Chesbro Memorial Scholarship Fund

This fund was established to provide scholarships to high school students who are graduating from any high school located within Franklin County and entering the field of public administration or political science.

Scholarships are awarded annually and dispersed in 2 equal payments in August and January. Scholarship award is renewable for up to 8 semesters, if eligibility criteria continues to be met.

Award

  • Varies

Scopes

  • Franklin County Community Foundation
Education - Higher Education Political Science

Thomas S. Ritter Memorial Scholarship Fund

Greater Kansas City Community Foundation
Private
United States
Unspecified amount

Thomas S. Ritter Memorial Scholarship Fund

The purpose of this scholarship fund is to assist students who are attending or plan to attend a college or university and who have demonstrated a strong work ethic both inside and outside of the classroom.

Award

  • Varies
Civil Engineering STEM / STEAM Education

ROSES25: D.8 Habitable Worlds Observatory Precursor Science Investigation

National Aeronautics and Space Administration (NASA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Habitable Worlds Observatory (HWO) is a pioneering space mission concept aimed at discovering life beyond our solar system, as highlighted in the Astro2020 survey. The HWO-PSI program seeks to reduce risks for future missions by advancing scientific investigations that inform mission design. As HWO enters its pre-formulation phase, it addresses significant astrophysical questions and technical challenges, ultimately striving for groundbreaking discoveries in our understanding of the universe.
Astronomy & Astrophysics Space Science

Remote Biomarker Measurements in Microphysiological Systems Grant

Translational Research Institute for Space Health
Association/Society
United States
Unspecified amount
The Remote Biomarker Measurements in Microphysiological Systems Grant seeks innovative proposals to enhance remote biomarker analysis technologies for microphysiological systems, crucial for deep space missions. It prioritizes non-invasive, adaptable methods that allow for continuous monitoring of biomarkers without sample return. This initiative aims to advance personalized healthcare and biological research, addressing astronaut health in challenging environments. Eligible entities include U.S. institutions and collaborations with foreign entities under specific conditions.
Astrobiology Space Science

Zimmer Biomet Foundation: Educational Grants

Zimmer Biomet Foundation Inc
Private
Africa, Americas +3 more
Unspecified amount
The Zimmer Biomet Foundation offers educational grants to support organizations that focus on scientific, clinical, or healthcare education. These grants promote educational programs, independent conferences, and resident education, ensuring that the content remains unbiased and free from influence. Eligible applicants include educational institutions, training hospitals, and medical associations, while requests from individuals or private practices are not supported. By fostering education in healthcare, the foundation aims to improve community well-being and advance medical knowledge.
Health & Medicine Medical Education & Professional Training

NEA Arts and Artifacts International Indemnity Program 1, FY2027 (9/26)

National Endowment for the Arts
Federal Government
American Samoa, Guam +4 more
US $1,000 - US $100,000
The NEA Arts and Artifacts International Indemnity Program provides essential support for U.S. museums by minimizing insurance costs for international exhibitions. Established in 1975 and expanded in 2007, this program allows museums to exhibit significant art and artifacts while protecting them from potential losses. Administered by the National Endowment for the Arts, the program evaluates applications through advisory panels, ensuring a thorough review process before indemnity agreements are approved.
Art & Culture Arts / Culture Access & Participation

John A. & Louise V. Maslin Scholarship

Delaware Community Foundation
Private
United States
US $1,000

John A. & Louise V. Maslin Scholarship

Essay:

  • On the topic “The Importance of Art, Science or Math in Society.”

Award:

  • One time award of $1,000.
Mathematics Education - Higher Education Science

Lisa Libraries Book Grants

Lisa Libraries
Private
United States
Unspecified amount in in-kind support
The Lisa Libraries Book Grants provide essential resources to organizations in low-income or underserved areas, enabling them to establish or enhance small libraries. Founded in 1990 to honor children's book editor Lisa Novak, the initiative has donated over one million books to help children gain access to literature. If your organization serves children in need of books, consider applying for support to create a nurturing reading environment.
Library Services Literacy

Thomas R. and Catharine G. Allan Scholarship Fund

Battle Creek Community Foundation
Private
United States
Unspecified amount

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Thomas R. and Catharine G. Allan Scholarship Fund

The Thomas R. and Catharine G. Allan Scholarship was established in memory of Thomas R. and Catharine G. Allan who thought it was important to further your education. The scholarship assists graduating seniors and graduates from Calhoun County public and private high schools pursuing postsecondary educational opportunities in teacher education.

Education Education - Higher Education

CORE Funding: AHNS/AAO-HNSF Translational Innovator Award

American Academy of Otolaryngology - Head & Neck Surgery Foundation
Private
United States
Up to US $100,000
The CORE Funding: AHNS/AAO-HNSF Translational Innovator Award supports innovative research in head and neck neoplastic diseases with a grant of $100,000 over two years. Eligible applicants include full-time academic head and neck surgeons, who must demonstrate a commitment to developing independent research careers. The award encourages interdisciplinary collaboration and aims to yield significant findings within the funding period, fostering long-term research potential and attracting further funding opportunities.
Health & Medicine Medical Education & Professional Training Otorhinolaryngology

NEA Arts and Artifacts International Indemnity Program 2, FY2027 (3/27)

National Endowment for the Arts
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $100,000
The NEA Arts and Artifacts International Indemnity Program, established in 1975, supports the exhibition of significant art and artifacts by minimizing insurance costs for international exhibitions. Administered by the National Endowment for the Arts, it covers U.S. owned art during exhibitions in the country. The program evaluates applications through advisory panels and the Federal Council on the Arts and Humanities, ensuring that vital cultural works are accessible while providing necessary financial protections.
Art & Culture Arts / Culture Access & Participation

AWWA Scholarship Program - AWWA Larson Aquatic Research Support Scholarships

American Water Works Association (AWWA)
Association/Society
North America
US $5,000 - US $7,000
The AWWA Larson Aquatic Research Support Scholarships, administered by the American Water Works Association, honor Dr. Thurston E. Larson by providing financial support for graduate students in science or engineering. Annually, two scholarships are awarded: $5,000 for master's students and $7,000 for doctoral students. This initiative reflects AWWA's commitment to fostering future leaders in the water industry while recognizing the contributions of Dr. Larson.
Engineering Science Academic Scholarship Programs

NEA Arts and Artifacts Domestic Indemnity Program 1, FY2027 (12/26)

National Endowment for the Arts
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $100,000
The NEA Arts and Artifacts Domestic Indemnity Program, administered by the National Endowment for the Arts, ensures that U.S. museums can exhibit significant art and artifacts without the burden of high insurance costs. Established in 1975, it provides indemnity against loss or damage, promoting access to cultural heritage. The program evaluates applications through expert advisory panels and typically meets three to six months after deadlines to decide on indemnity requests, thereby supporting the arts and enriching public engagement.
Art & Culture Arts / Culture Access & Participation

Large Grants for Nonprofit Organizations in Missouri Highlights

Looking for large grants for nonprofit organizations in Missouri?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in Missouri recommended for your specific programs.

Grant Insights : Large Grants for Nonprofit Organizations in Missouri

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Large Grants for Nonprofit Organizations in Missouri grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Large Grants for Nonprofit Organizations in Missouri over $25K in average grant size

29 Large Grants for Nonprofit Organizations in Missouri over $50K in average grant size

25 Large Grants for Nonprofit Organizations in Missouri supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in Missouri supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in Missouri?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in Missouri?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in Missouri year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in Missouri given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in Missouri changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081