Best Seed Grants for Nonprofits in Missouri

The Southern NM Down Syndrome Families Scholarship Fund Endowment aims to provide financial support for individuals with Down syndrome pursuing post-secondary education or life skills training at accredited institutions. Managed by the Community Foundation of Southern New Mexico, this scholarship embodies the mission of improving quality of life and fostering educational opportunities for diverse communities. It encourages applicants from various backgrounds, including those with disabilities, to achieve their academic and personal goals.

CDC Foundation

The CDC Foundation helps the Centers for Disease Control and Prevention (CDC) and the public health system save and improve lives by unleashing the power of partnerships to protect the health, safety and security of all communities, everywhere. The CDC Foundation is authorized by Congress to mobilize philanthropic partners, corporations, organizations and individuals to support the critical health protection mission of CDC and the public health system.

The CDC Foundation manages hundreds of programs each year aimed at protecting communities across the country from a variety of health threats—from chronic disease conditions including cardiovascular disease and cancer, to infectious diseases like malaria and HIV to emergency responses, such as Ebola and Zika.

Contractor for Implementation and Evaluation of Healthy Native Babies Project Materials

The CDC Foundation invites proposals from Tribes, Tribal Serving Organizations (TSOs), and Urban Indian Organizations (UIOs) [T/TSOs/UIOs] to implement and evaluate the implementation of the updated Healthy Native Babies Project (HNBP) materials within their service areas. This initiative aims to strengthen culturally relevant infant safe sleep education, increase community awareness and support Native families in reducing sleep related infant deaths. Selected T/TSOs/UIOs will adapt, disseminate and assess the use of HNBP materials in ways that reflect the cultural, linguistic and community-specific needs of the Native populations they serve.

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5429 - Bioavailability and Transformation of Dissolved Organic Nitrogen and Phosphorus Across WRRFs

Project Objectives

• Survey and characterize dissolved organic nitrogen and phosphorus (DON/DOP) concentrations and speciation across North American wastewater facilities, including but not limited to influent, secondary effluent, tertiary effluent, digester supernatant, thermal hydrolysis process (THP) centrate, autothermal thermophilic digestion (ATAD) sidestreams, and dewatering recycle streams.
• Understand the dynamics of DON/DOP in effluent, including quantifying the bioavailable fraction of DON/DOP in different relevant process streams, evaluating their transformation into nitrogenous disinfection by-product (N-DBP) precursors, determining bio-uptake rates representative of receiving water conditions, and measuring the timescale for biodegradation in receiving waters.

The Tick-borne Pathogen Award, sponsored by Bay Area Lyme Foundation, offers $150,000 to support innovative research on non-Borrelia tick-borne pathogens. This grant aims to attract scientific talent to explore co-infections with Lyme disease and other related infections. Eligible candidates include researchers from academia or the private sector at the post-doctoral level or higher, with a focus on improving diagnostics and therapies for tick-borne diseases. Applications must present a viable proof-of-concept project.

The NEA Federal Rescue Implementation Network Grant provides up to $100,000 per year for two years to state affiliates for hiring a coordinator to implement the American Rescue Plan in support of public education. This funding is specifically for backfilling a position that must remain filled for at least ninety days, ensuring effective oversight of federal recovery initiatives within the affiliate.

The Rural Maternity and Obstetrics Management Strategies Program (Rural MOMS) aims to enhance access to maternity and obstetrics care in rural areas through collaborative networks. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative focuses on innovative strategies to improve healthcare delivery for mothers and infants in underserved regions, ensuring that quality care is accessible where it is needed most.

The TMCity Foundation Grant supports innovative research in neurocognitive healthcare, with funding ranging from $25,000 to $250,000. This grant aims to address critical challenges in mental health by fostering cutting-edge research and transformative technologies. Applicants, preferably 501(c)(3) organizations, can submit letters of inquiry on a rolling basis, with a focus on projects based in Southern California and the Greater Boston area. The Foundation is committed to catalyzing advancements in understanding the brain and delivering effective treatments.

Home

The Middle Run Foundation is a family-governed foundation based in Newark, Delaware. The Board of the foundation is chaired by Sarah Ives Gore, its founder, and includes her children, grandchildren, and non-family members who bring experience and expertise to our work.

About

Purpose:

The purpose of the foundation is to fund and support non-profit programs which focus on building healthy, self-sufficient families.

Apply

The Middle Run Foundation makes grants up to $500,000 annually with individual grants ranging from $5,000 to $50,000.

The Health & Wellness Agency Grant, offered by the Jack and Jill of America Foundation, aims to empower disadvantaged communities by providing access to heart and mental health education. This grant supports 501(c)(3) organizations that align with the foundation's mission to enhance the well-being of African American children and families. Eligible applicants can receive funding to implement impactful health initiatives, while ineligible expenses include scholarships and operational costs.

Building the Future Workforce Challenge

Awarding $5 million and the opportunity to test bold, tech‑forward solutions that strengthen the advanced manufacturing and industry technician workforce—today and for the future.

About the Challenge

Caterpillar knows preparing the workforce for the future is urgent. Communities, employers, and industry need new ways to close advancing skill gaps. The Building the Future Workforce Challenge invites fresh perspectives from all sectors to rethink training. Up to five teams will be awarded $1 million each for sustainable, tech‑forward solutions that strengthen today’s—and tomorrow’s—advanced manufacturing and industry technician talent pipelines.

What types of solutions are you looking for?

The Building the Future Workforce Challenge aims to identify, test, and scale innovative, sustainable solutions that will address today’s and tomorrow’s advanced manufacturing and industry technician skill gaps. A core requirement of any solution is that it remains relevant amid evolving technology—ensuring that breakthrough innovation and human potential rise together.

Strong proposals for Building the Future Workforce Challenge will meet four criteria outlined in the scoring rubric, and proposed solutions must focus on one or more of the following solution categories for Building the Future Workforce Challenge:

The COPIC Medical Foundation Grants aim to improve healthcare outcomes by funding programs that enhance patient safety and reduce medical errors. With over $10 million awarded since its inception in 1991, the foundation focuses on scalable solutions to address healthcare fragmentation. This final grant cycle emphasizes innovative approaches that can be replicated across the healthcare community. Organizations must be 501(c)(3) certified or have a fiduciary partner to qualify for funding.

The Downing-Nix Trust Grant provides funding for organizations engaged in research on muscular dystrophy, maintaining treatment wards in Atlanta hospitals, offering veterinary medicine scholarships, and supporting shelters for small animals. Organizations must qualify as 501(c)(3) charities. Applications are accepted year-round, but submissions by April 15 are required for annual meeting reviews. Priority may be given to hospitals and veterinary schools within Atlanta, GA.

The SAF National Awards Program honors individuals in forestry for their innovative contributions to diversity and inclusion. Notably, the Cultural and Community Engagement Award recognizes SAF members who exemplify leadership in these areas. This award not only includes a $500 honorarium but also offers complimentary registration to the SAF convention and additional funds for travel. It highlights the importance of fostering an inclusive culture within the forestry profession.

The AWWA Scholarships Program, led by the American Water Works Association, aims to support the future of the water industry by investing in students. The Mueller Water Products Continuing Education Scholarship awards $5,000 to an undergraduate student employed by a water utility, emphasizing the importance of practical experience in education. This scholarship not only aids financial needs but also encourages students to pursue careers in water supply, fostering growth in this vital sector.

The Avant Garde Award supports innovative research on HIV and substance use disorders, encouraging creative scientists to explore high-risk, high-reward approaches. While applications are not currently being accepted, this initiative by the National Institute on Drug Abuse (NIDA) aims to stimulate collaborations and impactful research. Early-stage investigators are particularly encouraged to consider this opportunity as they develop their proposals for future funding. The program uses the DP1 activity code, fostering transformative advancements in biomedical and behavioral science.

WHO ARE WE?

In 2020, Jackson County was home to more than 165,000 children and youth under 18 years of age, and ranked 75th out of 114 Missouri counties for child welfare. Thirty-two percent of our county’s children under 6 years of age live in poverty. Twenty-five percent of our older kids do, too. Hundreds are victims of abuse or neglect. Thousands require clinical psychiatric care. A prior needs assessment of funding for children’s services in Jackson County revealed an annual funding gap of over $21M. CSF exists to change this story. Uniting care, connection, and creativity, we are providing opportunities to give hope to Jackson County kids.

CSF is an innovative way to support child well-being projects. While we are funded by a Jackson County sales tax, we are a stand-alone organization led by an independent board. We are committed to community equity. Our board is balanced to reflect our county, and we work to educate and support all applicants, so everyone—including small organizations and first-timers—has a fair shot at funding. We believe in fresh solutions, constant progress and collaboration. Our work allows us to see the whole-county picture, so we can connect like-minded partners and promote new collaborations.

CSF Core Funding

Core Funding is at the heart of our mission to make transformative investments in the mental health and emotional well-being of children in Jackson County. It supports organizations dedicated to improving the lives of children and families, enabling them to provide essential services that strengthen protective factors, mental health and social-emotional well-being. This funding is central to creating lasting impact, ensuring that every child has the opportunity to thrive.

Organizations can access Core Funding through two different funding cycles to best meet the needs of the organization. For traditional non-profit organizations, calendar year funding (January 1 – December 31) is the intended option to provide support. For schools and school-based/school-adjacent services, academic year funding (July 1 – June 30) is available. Both cycles follow a clear and structured process for requesting and awarding funds, with flexibility to suit different program needs. The application process has been streamlined to allow for more equitable access, with applicants now engaging in in-person presentations rather than submitting lengthy applications. This change fosters stronger relationships between the CSF and funded partners and levels the playing field for all organizations.

CSF can fund:

• Up to 30 days of temporary shelter, respite care and services for unwed mothers.
• Outpatient treatment, transitional living services, family intervention, crisis services and prevention programs.
• Professional counseling, psychological evaluations and mental health screenings.

Samardzija-Gutesha Family Fund

The Field of Interest Fund reflects the Samardzija-Gutesha family’s values and commitment to giving back. It supports education and hands-on learning in farming, soil health, and water conservation, with a focus on FFA members and associate-level college students.

Scholarships benefit graduating seniors and second-year post-high school students who are originally from DeKalb County high schools with FFA programs.

The Samardzija-Gutesha Family Fund provides scholarships for post-high school students pursuing education in agriculture or conservation, as well as paid internships with local farmers, and conservation professionals. It also supports educational seminars on topics such as sustainable farming and agricultural business, and provides grants to local organizations that align with the donor’s values.

In its first year, the Fund awarded $65,000 in scholarships to eight graduating seniors from DeKalb, Genoa-Kingston, Indian Creek, Somonauk, and Sycamore high schools (pictured above). Each student attending a two-year college received a $5,000 scholarship, while students planning to attend a four-year university received $10,000.

The Susie Kubié Symphonic Music Scholarship, established in 2017, provides financial support to talented young musicians from the Albuquerque Youth Symphony Program (AYSP). Each year, up to $4,000 is awarded to new or renewing scholars pursuing a music degree. Applicants are required to submit a personal essay, letters of reference, and a video performance. This scholarship not only aids students in their educational pursuits but also honors Susie Kubié's legacy of dedication to music education.

The NASPGHAN Foundation Abbott Advanced Fellowship in Pediatric Nutrition offers up to $75,000 for one year of advanced training in pediatric nutrition for members of NASPGHAN. This fellowship aims to enhance pediatric nutrition expertise by supporting a well-defined clinical experience and focused research project. Eligible applicants must be MDs or DOs and members in good standing, with a preference for those seeking training at different institutions. This initiative addresses the increasing importance of pediatric nutrition in child health.

The National Institute on Drug Abuse (NIDA) invites applications for longitudinal cohort studies focusing on HIV and substance use. This initiative aims to foster multidisciplinary research addressing HIV-associated co-morbidities and substance use disorders. The program encourages collaboration with a NIDA-funded Coordinating Center to enhance research agendas that align with NIH-HIV priorities, ensuring impactful policy and practice outcomes in the field of HIV/AIDS and substance use.

The Dr. Carol J. Chrisman Nursing Scholarship, offered by the Ashland County Community Foundation, supports registered nurses and nursing students from Ashland County pursuing advanced degrees at Ashland University. This scholarship honors Dr. Chrisman's legacy in nursing and community health, encouraging local nurses to further their education. Eligible applicants include full-time nursing students and those employed in public health within the area, with prior recipients allowed to reapply once.

The AWWA Scholarship Program, specifically the Veolia Water Technologies & Solutions Vernon D. Lucy III Scholarship, offers a $5000 award to undergraduate students pursuing careers in the water sector. Established by the American Water Works Association, this scholarship honors the mentorship of Vernon D. Lucy III and aims to support the next generation of water industry professionals. Eligible candidates must demonstrate interest in water-related fields, underscoring AWWA's commitment to fostering future leaders.

The Partners in Arts Scholarship, administered by the East Texas Communities Foundation, supports graduating seniors from Smith County who have engaged in performing or visual arts and plan to pursue a related major in college. This scholarship highlights the importance of arts education and aims to empower students to achieve their academic goals. Eligible applicants must demonstrate a commitment to the arts and meet specific criteria, ensuring that funding is awarded to deserving candidates.

The Dementia CAReS Grants aim to enhance the lives of American Indian and Alaska Native communities affected by dementia. By providing funding, training, and support, this initiative focuses on developing actionable strategies within Tribal and Urban Indian settings. Key activities include establishing a network of dementia champions and promoting local best practices. The goal is to empower communities to improve dementia care and outcomes through collaborative efforts and innovative approaches.

The Indigenous Scholarships: Arts Fund facilitates artistic development for Aboriginal Australian, Torres Strait Islander, Native American, Alaskan Native, and Native Hawaiian artists. Offering up to $5,000, it supports projects in each other's countries, with applications due in March and September. Since 2002, over $1 million has been awarded to more than 500 artists, fostering cultural exchange and growth in the arts between Australia and the USA.

The Native Forward Scholars Fund Internship Assistance Program empowers Native students by providing financial support for internships in non-STEM fields. This initiative breaks down financial barriers, enabling students to gain practical experience in areas like public policy, education, and cultural preservation. Through this program, students enhance their skills while contributing positively to their Tribal communities. The funding covers essential costs such as travel and living expenses, ensuring transparency and accountability in financial assistance.

The Best Buy Teen Tech Center is offering a Mini Tech Skills Workshop Grant to support local and national non-profits in providing STEAM skills workshops for youth aged 13-19. These workshops, which include topics such as coding, filmmaking, and robotics, aim to enhance technical skills and career exploration. Funding can reach up to $24,999, with a focus on hands-on, facilitator-led experiences, and additional programming opportunities may be considered.