Area Development Grant Program
The Area Development Grant Program, managed by the Appalachian Regional Commission (ARC), supports economic growth in Appalachia through investments in critical infrastructure and workforce development. Targeting 423 counties across 13 states, the program encourages local communities to collaborate with state governments to identify and implement impactful projects. Key focus areas include enhancing utilities, promoting entrepreneurship, and strengthening local leadership. This initiative aims to uplift the 26 million residents of Appalachia, fostering sustainable economic opportunities.
Appalachian Regional Commission
Clancy & Theys 1949 Fund
The Clancy & Theys 1949 Fund, managed by the Triangle Community Foundation, supports nonprofits in Central Florida, North Carolina, Upstate South Carolina, and Virginia. This donor-advised fund prioritizes initiatives in education, workforce development, youth programming, and community well-being, focusing on measurable impacts. The Foundation seeks to strengthen community ties and enhance quality of life by connecting donors with local organizations that address pressing needs. Both established partners and new applicants are encouraged to apply.
Triangle Community Foundation
First Horizon Foundation Grants (North Carolina and South Carolina)
The First Horizon Foundation, established by First Horizon National Corp., supports communities in Florida, North Carolina, and South Carolina. Since 1993, it has donated over $90 million to enhance lives through grants focused on arts, education, environment, financial literacy, and health services. Eligible nonprofits in various cities can apply, while individuals and certain organizations, such as K-12 schools and political groups, are excluded from funding. This foundation is dedicated to making a positive impact in the regions it serves.
First Horizon Foundation
Harris & Frances Block Foundation Grant
The Harris and Frances Block Foundation, established in 2001, supports small grassroots organizations focused on social and environmental justice. They prioritize equitable solutions and sustainable community development, funding initiatives related to environmental education, justice, and food security. Grants are available to non-profit, tax-exempt organizations in specific geographical areas including Vermont, North Carolina, Virginia, and New York City, excluding funding for lobbying, land acquisition, and scholarships.
Harris and Frances Block Foundation
Levine Foundation Grants
The Leon Levine Foundation, established in 1980, focuses on enhancing the human condition through investments in education, healthcare, and human services in North and South Carolina. The foundation seeks nonprofits with proven leadership and sustainable financial plans. They aim to create pathways to self-sufficiency and promote lasting change. LOIs are accepted year-round, and grant recipients must support an inclusive environment free from discrimination.
Leon Levine Foundation
Pentair Foundation Grants
The Pentair Foundation, a corporate philanthropy initiative, focuses on creating sustainable communities through water solutions and STEM education. With over $80 million in contributions since 1998, the foundation emphasizes ecological resilience, water quality improvement, and youth engagement in science and technology. They prioritize grantmaking in specific U.S. states and international regions, fostering vibrant communities and encouraging employee volunteerism. Initiatives are invitation-only, ensuring a targeted approach to impactful philanthropy.
Pentair Foundation
Pratt Family Foundation Grant
The Pratt Family Foundation Grant, established in 1999, supports initiatives in education, healthcare, and community welfare. It prioritizes organizations that aid housing assistance, support for women in crisis, and disadvantaged youth programs, particularly in North Carolina. The Foundation favors established religious and charitable organizations that are tax-exempt and have a local presence. Preference is given to areas connected to the Pratt family, such as Texas and Florida, ensuring impactful contributions to community development.
Pratt Family Foundation Inc.
Professional Development Grants for Arts Organizations
South Arts, Inc. offers Professional Development Grants for Arts Organizations to enhance the skills and knowledge of Southern arts entities. These grants aim to support operational stability and growth, focusing on organizations with budgets of $500,000 or less. Eligible applicants include a range of arts organizations within South Arts' nine-state service area. The program emphasizes first-time opportunities and requires a dollar-for-dollar cash match, ensuring a commitment to professional development in the arts.
South Arts, Inc.
Charlie's Heart Foundation Annual Grant Program
Full proposal due Jun 30, 2026
Charlie's Heart Foundation Annual Grant Program supports small nonprofits focusing on mental well-being for families in underserved communities. Grants between $5,000-$30,000 are available, prioritizing organizations based in North Carolina. Eligible applicants must be 501(c)(3) tax-exempt and demonstrate alignment with the Foundation's mission, organizational need, and program sustainability. The Foundation does not fund individuals, private foundations, or religious organizations, ensuring a strong focus on impactful community programs.
Charlie's Heart Foundation
Samuel L. Phillips Family Foundation Grant
Applications due Jun 30, 2026
The Samuel L. Phillips Family Foundation Grant, established in 2000, aims to enhance the quality of life in Mitchell County, NC, by supporting charitable organizations. The foundation emphasizes education, health, arts, and human services, prioritizing measurable impacts in the local community. Eligible organizations must be 501(c)(3) exempt and align with the foundation's mission. Note that the foundation does not fund individual grants or operating expenses. Applications are accepted year-round, with annual reviews occurring after June 30.
Samuel L. Phillips Family Foundation
NCGSK Foundation: Ribbon of Hope Grant
Applications due Jul 1, 2026
The North Carolina GlaxoSmithKline Foundation offers the Ribbon of Hope Grant, providing one-time funding of $25,000 for innovative projects that enhance science, health, and education in local communities. This initiative aims to address critical community needs while promoting sustainability. Eligible applicants include North Carolina-based nonprofit organizations exempt under Section 501(c)(3). The Foundation prioritizes proposals that align with local agency goals and demonstrate long-term viability beyond the grant period.
North Carolina GlaxoSmithKline Foundation
Impact Fund Grants
Letter of inquiry due Jul 7, 2026
The Impact Fund provides recoverable grants to legal services nonprofits and small law firms working on social, environmental, and economic justice issues. With over $10 million awarded since 1992, the fund supports impactful litigation addressing systemic injustices. Grants range from $10,000 to $50,000 and prioritize cases directly involving affected communities. Recipients must repay the grant amount with interest if they recover fees or costs, ensuring sustainability for future funding.
The Impact Fund
State-Level Systemic Change Grant
Applications due Jul 30, 2026
The Z. Smith Reynolds Foundation invites eligible organizations to apply for the State-Level Systemic Change Grant. This grant supports initiatives aimed at creating lasting, systemic improvements across North Carolina. Emphasizing equity and inclusion, the Foundation seeks to address barriers faced by historically marginalized communities, ensuring access to quality education, a healthy environment, and economic opportunities. This grant aligns with the Foundation's mission to foster a thriving, equitable society for all North Carolinians.
Z. Smith Reynolds Foundation
RHI Legacy Foundation Grant
Applications due Jul 31, 2026
The RHI Legacy Foundation Grant aims to enhance health and wellness in Rutherford County, NC, through funding community-focused programs. It prioritizes initiatives addressing chronic diseases, healthy eating, and active living, ensuring measurable impacts on the local population. Eligible organizations must be 501(c)(3) non-profits and demonstrate alignment with the Foundation's mission. The grant supports sustainable projects that improve overall community health and quality of life.
RHI Legacy Foundation, Inc.
Annual Grants: Human Services & Arts Requests
Applications due Aug 3, 2026
The John William Pope Foundation provides annual grants focusing on human services and the arts, primarily in North Carolina's Wake and Vance Counties. Established in 1986, the Foundation promotes self-reliance and community responsibility, funding initiatives that address critical social challenges. By prioritizing private resources over government funding, it fosters creative expression and supports nonprofits that empower individuals and families. The Foundation's mission is to ensure future generations have equal opportunities for success.
John William Pope Foundation
Brown Family Foundation Grant
Letter of inquiry due Aug 10, 2026
The Brown Family Foundation Grant aims to support small nonprofits in North and South Carolina, focusing on humanitarian efforts, education, and community improvement. With grants typically ranging from $5,000 to $50,000, the Foundation seeks to fund initiatives that demonstrate clear impact and sustainability. The Foundation prioritizes organizations that align with its mission and values, emphasizing collaboration and evidence-based practices. It does not fund individuals or certain types of organizations, ensuring that aid is directed effectively to those in need.
Brown Family Foundation
Merancas Foundation Grants
Applications due Aug 16, 2026
The Merancas Foundation, established in 1989, is a private foundation based in Charlotte, NC. It supports 501(c)(3) nonprofits focused on providing pathways to self-sufficiency and helping individuals in crisis. Grants are available for initiatives in education, housing, and wellbeing within specific geographic areas, including Atlanta, Charlotte, and Trenton. The foundation aims to empower communities while ensuring that its support aligns with its mission and values.
Merancas Foundation
Human Services and Education Grant
Applications due Aug 28, 2026
The Human Services and Education Grant, offered by The Community Foundation of Western North Carolina, provides up to $25,000 to support programs addressing the needs of economically disadvantaged individuals and educational initiatives. Grants aim to enhance early childhood development, K-12 education, and adult learning opportunities. Eligible organizations must serve specific WNC counties and demonstrate sustainability. However, the fund does not cover general operating expenses or support for capital projects. This grant cycle encourages impactful community-focused projects.
The Community Foundation of Western North Carolina
The Jandy Ammons Foundation Grant
Full proposal due Sep 11, 2026
The Jandy Ammons Foundation, established in 2012, is committed to enhancing local communities through innovative, project-driven initiatives. Focused on 'shovel ready' projects, it supports wildlife conservation, educational efforts, artistic installations, and Christian mission endeavors. By providing resources to IRS-recognized 501(c)(3) charities, the foundation aims to inspire community engagement and sustainable growth. The foundation reflects the collaborative spirit of its founders, Andy and Jan Ammons, who believe in hard work, integrity, and maximizing available resources.
The Jandy Ammons Foundation
Toyota Battery Manufacturing North Carolina (TBMNC) Grants
Applications due Oct 1, 2026
Toyota Battery Manufacturing North Carolina (TBMNC) Grants aim to enhance community well-being by investing in nonprofit organizations that focus on community sustainability, inclusive mobility, and workforce readiness. This corporate initiative seeks partnerships with qualified 501(c)(3) nonprofits, public schools, and municipal organizations in the Randolph and Guilford counties. By supporting programs with a long-term impact, Toyota fosters a culture of inclusion and aims to address pressing societal challenges.
Toyota
Programmatic Support - Environment Pillar Award
Applications due Nov 1, 2026
The Environment Pillar Award by Honda supports nonprofit organizations and schools in the U.S. focused on sustainability. Grants aim to reduce environmental impact through programs in decarbonization, clean energy, and efficient resource use. Eligible projects must align with Honda's mission and primarily benefit communities where Honda associates live and work. Organizations can apply for up to two grants, provided they meet specific eligibility criteria, including tax-exempt status under the IRS.
American Honda Motor Co., Inc.
The Duke Endowment: Health Care Grant
Pre proposal due Nov 15, 2026
The Duke Endowment's Health Care Grant aims to enhance health equity in North and South Carolina. Established in 1924, it supports innovative models addressing health disparities in vulnerable populations, focusing on access to care, maternal and infant health, mental health, oral health, and workforce development. By partnering with local stakeholders, the Endowment strives to reduce barriers to care and promote healthy behaviors, ultimately improving health outcomes for marginalized communities.
The Duke Endowment
Duke Endowment: Child and Family Well-Being Grant
Pre proposal due Dec 15, 2026
The Duke Endowment's Child and Family Well-Being Grant provides implementation support to public and private agencies in North and South Carolina. This funding aims to adopt and sustain evidence-based programs that prevent and treat child maltreatment. Eligible organizations must have two years of audited financial statements and work with accredited groups. The grant prioritizes innovative solutions and advocacy to improve child welfare systems, ensuring effective support for children and families at risk.
The Duke Endowment
Women for Women Grant
Applications due Feb 10, 2027
The Women for Women Grant aims to enhance the lives of women and girls in Western North Carolina through collective giving. With over $5 million invested since 2006, the grant supports programs focused on self-sufficiency for economically disadvantaged women, including workforce training, mentorship, and childcare access. Organizations can receive funding ranging from $15,000 to $125,000 based on project needs, fostering equity and dismantling discriminatory systems in the community.
The Community Foundation of Western North Carolina
Rural Arts Initiative Grant Program
Applications due Mar 6, 2027
The Rural Arts Initiative Grant Program, established by the Laura Jane Musser Fund, aims to support nonprofit arts organizations in rural communities. The program encourages access to the arts through scholarships, community engagement, and innovative activities. Priority is given to organizations located in areas with populations under 20,000, ensuring that artistic opportunities are available to both adults and children. Applications are accepted for one year of funding, with potential for up to three consecutive years.
Laura Jane Musser Fund
Dogwood Health Trust: Collaboration & Innovation Grant
Letter of inquiry due May 18, 2027
The Dogwood Health Trust: Collaboration & Innovation Grant aims to support innovative collaborations addressing the challenges faced by Western North Carolina communities post-Hurricane Helene. With grant sizes ranging from $50,000 to $500,000, this initiative focuses on fostering community-wide networks that enhance housing, education, and health. It prioritizes resources for underserved communities, encourages creative solutions, and strengthens coalitions to improve systemic responses to local needs, ensuring impactful and sustainable outcomes.
Dogwood Health Trust
Universal Leaf Foundation Grants
Applications due Jun 15, 2027
The Universal Leaf Foundation Grants support 501(c)(3) nonprofit organizations primarily in areas where Universal Leaf Tobacco Company operates. Focus areas include education for at-risk individuals, higher education, civic/community arts, and environmental initiatives. The Foundation emphasizes good corporate citizenship and community engagement through financial support and employee volunteerism. Organizations must operate within designated geographic areas and cannot be involved in political advocacy or restrict services based on demographics. Grants aim to enhance community well-being and educational opportunities.
Universal Corporation