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Best Operating Grants for Nonprofits in Ohio

Find the perfect Operating grants for nonprofits in Ohio on Instrumentl. 10,000+ Operating grants for nonprofits in Ohio in the United States.

10,000+

Available grants

$2.63B

Total funding

$5K

Median grant

10,000+ grants
$2.63B total
$5K median

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9,919 Results based on applied filters

RSLAAIS Leadership Award

American Academy of Allergy, Asthma & Immunology (AAAAI)
Association/Society
United States
Unspecified amount
The RSLAAIS Leadership Award, presented by the American Academy of Allergy, Asthma & Immunology (AAAAI), honors exemplary leaders within state, regional, or local allergy societies. This prestigious award recognizes individuals for their significant contributions to community involvement, clinical education, and the advancement of the AAAAI's mission. Candidates are nominated by the RSLAAIS Board of Governors and must demonstrate a commitment to enhancing their local allergy societies and the broader medical community.
Asthma Vaccines & Immunizations Immune System Diseases

Specialized Transportation Program (5310): Operating Assistance

Ohio Department of Transportation
State/Local Government
Adams County, Ohio, Allen County, Ohio +70 more
Unspecified amount

Ohio Department of Transportation

With a mission to provide a transportation system that is safe, accessible, well maintained, and positioned for the future, the Ohio Department of Transportation (ODOT) supports the state highway system and promotes transportation initiatives statewide. As a more than $3 billion per year enterprise, ODOT invests the bulk of its resources in system preservation through maintenance, construction, and snow and ice operations.

ODOT's regional district offices and Central Office divisions work together to fulfill the department's mission of providing safe and easy movement of people and goods from place to place.

Specialized Transportation Program (5310)

Program Goal and Description

The Specialized Transportation Program, as authorized by the Federal Transit Administration, 49 USC Section 5310, is intended to enhance mobility for seniors and persons with disabilities by providing Federal Transit Administration funds for programs in small urbanized and rural areas that serve the special needs of transit-dependent populations beyond traditional public transportation services and Americans with Disabilities Act (ADA) complementary paratransit services. The program provides 80% of the cost of capital projects; the remaining 20% must be provided by local funding, which may be derived from other federal (non-U.S. DOT) transportation sources or the Federal Lands Highway Program.

Project Types: Vehicle Funding; Preventive Maintenance (PM) Funding; Mobility Management Funding; Computer Hardware and/or Software & Equipment Funding; Operating Assistance; Contracted Transportation Service Funding

Operating Assistance

The objective of the 5310 operating assistance project is to provide financial support to subrecipients in the day-to-day transportation operations for seniors and persons with disabilities. Operating assistance funding is explicitly intended to be spent on operations. ODOT will reimburse 50% of the operating cost and the subrecipient is required to provide the 50% local match. All of the local match must be provided from sources other than U.S. Department of Transportation funds. To be eligible for Section 5310 operating funds, an applicant must provide open-door services. FTA defines open door as regular, continuing shared ride surface transportation services that is open to the public or open to a segment of the public defined by age or disability.

Disability Care & Services Senior Services Rural Development +1 more

Charles Hamlin Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount
The Charles Hamlin Scholarship, established by Nurses Educational Funds, Inc., supports professional nurses pursuing master's or doctoral degrees in nursing. Applicants must hold a current RN license and demonstrate a commitment to nursing leadership, particularly in orthopedic care and the well-being of Native American communities. The scholarship honors Dr. Charles Hamlin's legacy, emphasizing the importance of cultural sensitivity in healthcare and preventing burnout among healthcare professionals. This award aims to empower future nursing leaders and enhance diversity in the field.
Education - Higher Education Nursing Mental Health & Psychiatric Diseases +2 more

BJA FY 2026 Second Chance Act Community-based Reentry Program

US DOJ: OJP Bureau of Justice Assistance
Federal Government
United States
Up to US $1,000,000
The BJA FY 2026 Second Chance Act Community-based Reentry Program aims to support community organizations and tribal governments in providing essential mentoring and transitional services for individuals returning from correctional facilities. This initiative targets those assessed as moderate to high risk for recidivism, addressing their needs both pre-and post-release. By fostering successful reintegration into society, the program contributes to public safety and reduces recidivism rates, aligning with the mission of the U.S. Department of Justice.
Crime & Justice Reentry Services Employment Services +2 more

Cancer Prevention and Control Programs for State, Territorial, and Tribal Organizations (363855)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The Cancer Prevention and Control Programs aim to eliminate cancer through collaborative efforts among state, territorial, and tribal organizations. Funded by the CDC, this program supports initiatives such as breast and cervical cancer screening, cancer control planning, and cancer surveillance. By fostering partnerships and community involvement, the program seeks to improve health outcomes and achieve the mission of 'All People Free of Cancer.' This comprehensive approach ensures that resources are effectively coordinated to address the cancer burden in communities.
Cancer / Oncology Epidemiology & Public Health Health Care Access & Delivery +2 more

ASF Olin Fellowships

Atlantic Salmon Federation (ASF)
Private
Canada, United States
C $1,000 - C $3,000
The Atlantic Salmon Federation Olin Fellowships support individuals aiming to enhance their knowledge and skills in salmon conservation and management. These fellowships are available annually for various pursuits, including research and graduate studies, without the requirement of being enrolled in a degree program. Eligible applicants must be legal residents of the U.S. or Canada, and the fellowships can be conducted at accredited institutions or active management programs.
Ichthyology (Fish) Fisheries

Greenawalt Foundation Skilled Trades Program Grant

Greenawalt Foundation
Private
United States
Unspecified amount

Greenawalt Foundation

Building Stronger Communities

At The Greenawalt Foundation, we believe that opportunity is the foundation of prosperity. By supporting organizations that educate, train, and empower people in the trades, we’re helping to build a stronger, more sustainable future for all.

Skilled Trades Grant Opportunities

The Greenawalt Foundation advances opportunities in the skilled trades through funding for accredited pre-apprenticeship and apprenticeship programs, workforce training initiatives, and youth career exploration experiences. These programs promote technical readiness and connect STEM education to modern trades careers, building a stronger, more sustainable workforce. Foundation support focuses on expanding access and creating equitable pathways to prosperity for individuals pursuing skilled trades careers. Through these efforts, the Foundation helps develop the next generation of skilled professionals who will shape the future of our communities.

Eligible Grant Categories

  • Skilled Trades Training Support
  • Pre-Apprenticeship or Apprenticeship Programs
  • Youth Career Exploration Camps
Vocational & Trade Education Apprenticeship & Internship Programs Youth Development & Leadership +1 more

CFF Innovation Grants

COLIN FARRELL FOUNDATION
Private
United States
US $10,000 - US $50,000

About Colin Farrell FoundationThe Colin Farrell Foundation is committed to transforming the lives of individuals and families living with intellectual disability through education, awareness, advocacy, and innovative programs. Inspired by his two sons, he is excited and deeply humbled by the hope that the Colin Farrell Foundation can help those who the larger systems of governance have neglected.

CFF Innovation GrantsWe’re looking for bold, scalable solutions focused on one or more of these priority areas:

  • Affordable co-housing models for individuals and families
  • Employer-partnered day programs and inclusive job opportunities
  • Tools and technologies that enhance accessibility at home and in community spaces
  • Cross-sector collaborations between public, private, and nonprofit organizations

Intellectual / Developmental Disabilities Equitable & Affordable Housing Volunteerism & Philanthropy

Rita Reis Wieczorek Scholarship for Maternal-Infant and Pediatric Nursing

Nurses Educational Funds Inc.
Private
United States
Unspecified amount

Nurses Educational Funds

Nurses Educational Funds, Inc. depends solely on donations to advance our only mission, to promote nursing leadership through annual scholarship support for professional nurses seeking masters and doctoral degrees in nursing education, practice, research, and administration.

NEF’s only purpose is to provide nursing scholarship assistance to make graduate level nursing education possible. NEF is one of the largest, national, private, professionally endorsed source of funds for advanced nursing study with over one hundred years of service to and for professional nursing. NEF is a non-profit organization with 501(c) status.

Rita Reis Wieczorek Scholarship for Maternal-Infant and Pediatric Nursing

Created in 2020, by Rita Reis Wieczorek, EdD, RN, PNP, FAAN, together with NEF. Dr. Wieczorek is an NEF Board Member Emeritus and longtime board member. This scholarship is the first NEF Scholarship to focus on maternal-infant and pediatric nursing. For over four decades Dr. Wieczorek has devoted her career to providing the best maternal-infant and pediatric care to her patients as well as teaching the highest standards of care to master's and doctoral nursing students, motivating them to excel in their care for the well-being of mothers, infants and children.

Education - Higher Education Nursing Maternal And Perinatal Health +1 more

RRCU Gives Foundation Grant

RRCU Gives Foundation
Association/Society
United States
Unspecified amount

RRCU Gives Foundation Grant

Mission Statement:

RRCU Gives strengthens our region by providing meaningful financial support to nonprofits addressing hunger, housing, and financial education. Through our annual grant awards and major funding initiatives, we help local organizations grow, thrive, and create lasting change.

 We award grants annually, with applications in June and awards in August.

Focus Areas

  • Hunger
  • Housing
  • Financial Education
Food Access & Hunger Financial Literacy Equitable & Affordable Housing

Native Public Health Resilience

Indian Health Service
Federal Government
United States
Unspecified amount
The Native Public Health Resilience (NPHR) program is a new funding opportunity aimed at supporting Tribes and Tribal Organizations in delivering essential public health services. Sponsored by the Indian Health Service, this initiative seeks to bolster public health infrastructure and resilience within tribal communities, ensuring they have the necessary resources to address health challenges effectively. Eligible applicants will receive financial assistance to enhance their public health capabilities and improve community health outcomes.
Epidemiology & Public Health Health Care Access & Delivery Native American Services +2 more

AHRF Discovery Grants

American Hearing Research Foundation
Private
United States
Up to US $50,000
The AHRF Discovery Grants support innovative research on hearing and balance disorders, offering up to $50,000 for one year. Targeting early-career investigators, these grants aim to generate preliminary data for larger funding applications. Special consideration is given to projects exploring Meniere's disease and sudden hearing loss. Grants cover direct research costs, excluding principal investigator salaries and indirect expenses. The initiative strives to fund promising studies that can advance our understanding of auditory and vestibular health.
Hearing Disorders & Audiology Meniere’s Disease

Store-Based Giving Program Grant

Ross Stores Foundation
Private
United States
US $300 - US $500
The Store-Based Giving Program by Ross Stores Foundation supports socioeconomically disadvantaged youth by providing gift cards for school or professional clothing. Organizations must be federal tax-exempt and serve at least 60% low-income youth. Eligible programs include academic achievement and life skills initiatives. Award amounts typically range from $300 to $500, depending on budget and mission alignment. Applications are not accepted from organizations that have received donations within the past 12 months.
Youth Services Financial Literacy Career / College Preparation +2 more

Harry Kramer Memorial Fund Grant

Harry Kramer Memorial Fund
Private
Israel, United States
US $10,000 - US $25,000
The Harry Kramer Memorial Fund Grant supports U.S. charitable organizations that assist individuals and institutions in Israel, focusing on welfare, healthcare for the sick and aged, and education in South Florida. Founded by Harry A. Kramer, a successful entrepreneur and veteran, the fund reflects his deep commitment to charitable causes. Organizations must qualify under Section 501(c)(3) and meet specific eligibility criteria to apply for funding, ensuring that aid reaches those in need.
Jewish Culture Senior Services Religion & Spirituality +4 more

AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer (Fund B)

American Gastroenterological Association
Association/Society
North America
US $300,000
The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty in digestive disease research. This award aims to support independent careers in pancreatic cancer research by protecting a significant portion of the recipient's time for research activities. Eligible applicants must hold an MD, PhD, or equivalent and work at a North American institution, with AGA membership required. Strong encouragement is given to underrepresented groups.
Pancreatic Cancer

AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer (Fund A)

American Gastroenterological Association
Association/Society
North America
US $300,000
The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty focused on independent research in pancreatic cancer. This award aims to protect at least 50% of the recipient's time for research activities. Eligible applicants must hold an MD or PhD and be classified as early-career. The award encourages physician-scientists and underrepresented groups in biomedical research to apply, supporting innovative research that can lead to significant advancements in understanding pancreatic cancer.
Pancreatic Cancer

Survivorship and Supportive Care Research Grant

St Baldricks Foundation Inc
Private
United States
Up to US $50,000

St. Baldrick's Foundation

The St. Baldrick's Foundation is a volunteer and donor powered charity committed to supporting the most promising research to find cures for childhood cancers and give survivors long and healthy lives. It started with a friendly dare: would you shave your head to raise money for kids’ cancer research? What happened next would change the world. This bold act of baldness has gained major momentum, since its start in 2000. Today, we have more than 1,000 head-shaving events taking place around the world at pubs, restaurants, schools, churches, parks, firehouses, military bases – you name it. It is our constituents’ way of changing the world, in a meaningful way. Volunteers also raise funds through athletic challenges, livestream fundraisers and many other activities.

Since the Foundation's first grants as an independent charity in 2005, St. Baldrick's has invested more than $380 million in childhood cancer research grants worldwide.

About Allied World

Allied World Assurance Company Holdings, Ltd, through its subsidiaries, is a global provider of insurance and reinsurance solutions. The company operates under the brand Allied World and has supported clients, cedents and trading partners with thoughtful service and meaningful coverages since 2001. Since the inception of St. Baldrick’s, Allied World has supported childhood cancer research through the Foundation, and it is the largest of many reinsurance company sponsors, making this life-saving mission a top priority.

Survivorship and Supportive Care Research Grant

These grants are for specific one-year research projects which are hypothesis-driven and focus on areas related to survivorship and supportive care of children and adolescents with cancer. Examples include but are not limited to: studies related to the burden of morbidity, cause-specific mortality, understanding the pathogenesis of treatment-related complications, patient-reported outcomes or quality of life, health communication, health promotion, and psychosocial support across the trajectory from diagnosis to survivorship or end-of-life care.

Projects must have direct applicability and relevance to pediatric cancer. They may be in any discipline of basic, clinical, translational, or epidemiological research.

Cancer / Oncology Pediatric Cancers Patient Care & Services

AISES Indigenous Peoples Education Fund (IPEF) Scholarship

American Indian Science and Engineering Society (AISES)
Association/Society
American Samoa, Canada +5 more
US $5,000
The AISES Indigenous Peoples Education Fund (IPEF) Scholarship offers $5,000 to support Indigenous students pursuing degrees in STEM fields. This scholarship is available to current AISES members who are full-time students and enrolled citizens or descendants of recognized Native American tribes. AISES aims to empower these students, fostering diversity in STEM while recognizing the importance of education as a tool for personal growth and community development.
STEM / STEAM Education Diversity, Equity & Inclusion Academic Scholarship Programs +3 more

Never Let Go Fund

Emporia Community Foundation
Private
United States
Up to US $2,000

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Never Let Go Fund

The purpose of the Never Let Go Fund is to provide funds to qualified individuals to cover expenses related to the treatment of childhood cancer. Grant requests will be considered for children under the age of 18.

Health Care Access & Delivery Cancer / Oncology Children’s Health & Pediatrics +1 more

Madison Chautauqua Scholarship for the Arts in Memory of Bob Fourhman

Community Foundation of Madison and Jefferson County
Private
United States
US $1,800

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Madison Chautauqua Scholarship for the Arts in Memory of Bob Fourhman

Criteria evaluated:

  • Letter of recommendation and artwork samples

Required materials:

  • Letter of recommendation from a person knowledgeable about your talent and accomplishments in your art form; and
  • An uploaded sample of your work (maximum 3 photos or 1 short video/audio clip)

Scholarship amount:

  • $1,200 | 1 scholarship
Education - Higher Education Adult Education Career / College Preparation +3 more

Goodnow Fund Grants

Goodnow Fund
Private
United States
Unspecified amount
The Goodnow Fund is a family foundation that provides approximately $1.5 million in grants annually to nonprofit organizations. Focused on supporting vulnerable children, Alzheimer's research, educational opportunities for low-income students, and environmental improvement, the Fund primarily aids organizations in Fairfield County, Connecticut. It identifies potential grantees directly and does not accept unsolicited proposals. For more information, organizations can contact the Fund's Executive Director.
Dementia & Alzheimer’s Disease Child Welfare Services Environment +1 more

Ecosystem Health and Sustainable Fish Populations Grants: Ecological and Biological Research to Inform Management

Great Lakes Fisheries Trust
Private
Adams County, Indiana, Adams County, Wisconsin +127 more
Up to US $1,300,000
The Great Lakes Fisheries Trust offers grants for ecological and biological research aimed at enhancing ecosystem health and sustainable fish populations. These grants support competitive fisheries research, focusing on resilience, sustainability, and stakeholder value. The next funding cycle will open with a request for proposals in late 2026 for the 2027 program year, promoting innovative research and capacity-building efforts within the fisheries sector.
Ichthyology (Fish) Fisheries

MWDSC: Innovative Conservation Program Funding

The Metropolitan Water District of Southern California
State/Local Government
United States
Up to US $50,000
The Metropolitan Water District of Southern California's Innovative Conservation Program (ICP) has funded innovative water savings projects since 2001, with $250,000 available biannually. The program aims to evaluate and demonstrate the reliability of new water-saving technologies. Nearly 400 proposals have sought $36 million in funding. The ICP, supported by multiple agencies, encourages projects that can benefit Southern California's water efficiency, inviting proposals from outside its service area to enhance regional water management.
Water Resource Management

ABF Next Generation Research Grants - Stroke

American Brain Foundation
Private
United States
Up to US $150,000

American Brain Foundation

The American Brain Foundation funds research across the spectrum of the brain and nervous system, because it is our best hope for improving treatments, advancing prevention strategies, and discovering cures. Brain diseases, disorders, and injuries are interconnected. When we cure one, we will cure many.

Next Generation Research Grants

The American Brain Foundation’s Next Generation Research Grants (NGRGs) support early career investigators conducting high-quality research aimed at better understanding, treating, and curing brain diseases. These grants are offered in collaboration with disease-focused partner organizations and reflect ABF’s Cure One, Cure Many research philosophy: the belief that breakthroughs in one area of research accelerate progress across many others.

Lawrence M. Brass, MD Clinical Research Training Scholarship in Stroke

This award aims to recognize the importance of good clinical research and to encourage early career investigators in clinical studies related to stroke, vascular neurology, and neurocritical care.

For the purpose of this scholarship, research is defined as “patient-oriented research conducted with human participants, or translational research specifically designed to develop treatments or enhance diagnosis of neurological disease. These areas of research include epidemiologic or behavioral studies, clinical trials, studies of disease mechanisms, the development of new technologies, and health services and outcomes research.” Disease-related studies not directly involving humans or human tissue are also encouraged if the primary goal is the development of therapies, diagnostic tests, or other tools to prevent or mitigate neurological diseases.

Stroke Neuroscience Neurological Diseases & Disorders

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The SCORCH Program: Phase 2 aims to enhance the understanding of single cell biology in the context of HIV and Substance Use Disorder (SUD). Building on previous research, this initiative will explore new single cell approaches to investigate the interactions between SUD and HIV progression at various biological levels. By leveraging advanced techniques, the program seeks to identify candidate mechanisms and potential therapeutic targets, ultimately contributing to innovative solutions for SUDs and HIV-related challenges.
HIV / AIDS

Enhancing Pastoral and Social Ministry Grants

Catholic Extension
Association/Society
Acadia Parish, Louisiana, Accomack County, Virginia +994 more
Unspecified amount
Catholic Extension's Enhancing Pastoral and Social Ministry Grants aim to empower the church to broaden its outreach and foster societal transformation through targeted pastoral and social initiatives. This program supports specific elements of the church's ministerial efforts, including funding for catechetical resources, marriage and family ministries, and social outreach for vulnerable populations. By investing in these areas, Catholic Extension seeks to enhance the church's role in communities, especially following disasters.
Catholicism Family Services Homelessness Services +3 more

Marion Community Foundation: Community Grants

Marion Community Foundation
Private
Marion County, Ohio
Unspecified amount
The Marion Community Foundation's Community Grants Program aims to address pressing needs in Marion County, Ohio, by providing funding to local nonprofits. This initiative supports projects that enhance food security, health, education, and community development while encouraging innovative solutions to local challenges. Eligible organizations include 501(c)3 nonprofits, public schools, and governmental entities. The foundation seeks to empower nonprofits to propose transformative ideas that foster positive change and collaboration in the community.
Basic Human Needs Community Development & Revitalization Wellness & Healthy Living +6 more

Operating Grants for Nonprofits in Ohio Highlights

Looking for operating grants for nonprofits in Ohio?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in Ohio recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in Ohio

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Operating grants for nonprofits in Ohio grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

87 Operating grants for nonprofits in Ohio over $25K in average grant size

57 Operating grants for nonprofits in Ohio over $50K in average grant size

34 Operating grants for nonprofits in Ohio supporting general operating expenses

200+ Operating grants for nonprofits in Ohio supporting programs / projects

1,000+ Grants on Instrumentl focused on Mental Health & Psychiatric Diseases

700+ Grants on Instrumentl focused on Family Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Ohio?

Most grants are due in the first quarter.

Q1
28.5%
Q2
24.2%
Q3
24.9%
Q4
22.4%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Ohio?

Grants are most commonly $29,500.

$250 $250 Min.
$29,500 $29.5 K Median
$468,793 $468.8 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Ohio?

Grants are most commonly $97,851.

$97,851

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Ohio year over year?

In 2024, funders in Ohio awarded a total of 84,081 grants.

2022 78,879

2023 79,604

2024 84,081

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Ohio given out in Ohio, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Ohio changing over time?

Funding has increased by -1.54%.

2022 $7,853,771,046

2023 $8,315,467,696
5.88%

2024 $8,187,079,289
-1.54%

Ohio Counties That Receive the Most Funding

How does grant funding vary by county?

Hamilton County, Cuyahoga County, and Franklin County receive the most funding.

County Total Grant Funding in 2024
Hamilton County $3,320,115,009
Cuyahoga County $2,821,239,308
Franklin County $2,035,647,424
Summit County $545,376,601
Scioto County $393,048,909