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Best Operating Grants for Nonprofits in Ohio

Find the perfect Operating grants for nonprofits in Ohio on Instrumentl. 10,000+ Operating grants for nonprofits in Ohio in the United States.

10,000+

Available grants

$2.63B

Total funding

$5K

Median grant

10,000+ grants
$2.63B total
$5K median

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9,919 Results based on applied filters

Barberton Community Foundation: Small Grants

Barberton Community Foundation
Private
Summit County, Ohio
Up to US $5,000
The Barberton Community Foundation offers small grants of $5,000 or less to support local nonprofits, schools, and community initiatives. This foundation aims to enhance the quality of life for Barberton residents through collaborative efforts and impactful contributions. Interested applicants should submit a letter of inquiry before applying, as all requests are subject to review by the Foundation staff and Board Chair. The foundation prioritizes projects that directly benefit the citizens of Barberton.
Education Workforce Preparation & Job Readiness Economic Services & Development +3 more

TJX Foundation Grants

The Tjx Foundation Inc
Corporate
United States
Unspecified amount
The TJX Foundation Grants support nonprofit organizations located within 15 miles of a TJX store that align with their community mission. Eligible areas include basic needs, education for at-risk youth, workforce training, and safety from domestic violence. Organizations must be a registered 501(c)(3) for at least 12 months and have a nondiscrimination policy. Applications are invited through a Letter of Inquiry, with funding decisions based on community impact.
Basic Human Needs Workforce Preparation & Job Readiness Domestic Violence +1 more

Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance aims to enhance the capacity of ADAPs. By providing essential tools and expert guidance, the program seeks to improve health outcomes for individuals living with HIV in an evolving healthcare landscape. This initiative is funded by the US HHS through the Health Resources & Services Administration, ensuring support and resources are effectively allocated to meet the needs of vulnerable populations.
HIV / AIDS

RFP- Rural Rental Housing Preservation Academy

Enterprise Community Partners Inc
Private
United States
Unspecified amount
The RFP for the Rural Rental Housing Preservation Academy offers no-cost training sessions aimed at empowering rural housing providers to acquire and preserve affordable housing financed by USDA, HUD, and LIHTC. Participants will engage in peer learning, receive targeted technical assistance, and access expert guidance tailored to their needs. This initiative seeks to enhance the preservation of affordable housing opportunities, particularly those with rental assistance, in rural communities across the region.
Equitable & Affordable Housing Homeownership

AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional) (362945)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Mental Health is inviting research applications for the AIDS Research Center program, which includes Developmental Centers and full Research Centers. This initiative aims to enhance interdisciplinary HIV/AIDS research through collaboration and innovative approaches across various scientific domains. The program emphasizes alignment with national strategies and encourages applications from teams skilled in fostering partnerships with diverse stakeholders. Although applications are currently not being solicited, this notice allows potential applicants time to prepare strong proposals.
HIV / AIDS

Improved Drug Susceptibility Testing (DST) for Mycobacteria

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.
Infectious & Parasitic Diseases Tuberculosis Drug-Resistant Bacteria

F26AS00071 Cooperative Endangered Species Conservation Fund: Habitat Conservation Plan Land Acquisition Grants

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $26,000,000
The Cooperative Endangered Species Conservation Fund supports habitat conservation through land acquisition grants. Established in 1997, this program aims to minimize conflicts between listed species conservation and land use. The U.S. Fish and Wildlife Service provides matching grants to state agencies for projects that ensure the long-term protection of habitats. By acquiring land or conservation easements, this initiative facilitates species recovery and helps prevent future listings under the Endangered Species Act, enhancing overall ecosystem health.
Environmental Conservation Habitat & Ecosystem Restoration Land / Habitat Conservation

Broad Street Children's Foundation Grant

Broad Street Childrens Foundation
Private
United States
Unspecified amount

Who We Are

Broad Street Children's Foundation is committed to providing financial support to privately funded children's homes caring for the orphaned, abandoned and broken children right here in the United States.

Grant Seekers

Broad Street Children's Foundation supports self-sustaining children's homes across the United States that actively foster the development of strong, well-rounded children in their care.

Since the start of the Foundation, over $1,000,000.00 in grants have been donated to children's homes across the country. Additionally, through the Bill and Jackie Hazelgrove Scholarship Program, we have been able to assist a number of young people to continue their education and work towards a college or vocational degree.

Today, the Broad Street Children's Foundation is continuing the dream of it's original founders through the second generation. Equally as dedicated to changing the lives of children in need across America and striving to break the cycle of abuse and neglect for other children and their families.

Child Welfare Services Vocational & Trade Education Child Abuse & Neglect +2 more

F26AS00105 National Fish Passage Program

Fish and Wildlife Service
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The National Fish Passage Program (NFPP) offers vital assistance for removing barriers to aquatic life, enhancing safety, and promoting local economies. By investing in projects like culvert replacements and floodplain restorations, the program not only supports native fish populations but also delivers significant economic benefits, estimated at $1.5 million for every $1 million invested. With a recent allocation of $15 million, including $5 million for specific restoration initiatives, NFPP continues to advance aquatic connectivity nationwide.
Habitat & Ecosystem Restoration Ichthyology (Fish) Fish Conservation

John H. Prescott Marine Mammal Rescue Assistance Grant (363929)

DOC NOAA - ERA Production
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The John H. Prescott Marine Mammal Rescue Assistance Grant supports the recovery and care of sick or injured marine mammals through federal assistance to the U.S. National Marine Mammal Stranding and Entanglement Response Networks. Eligible applicants must provide a Prescott Letter of Eligibility, confirming their participation in the network. This program aims to enhance marine mammal health monitoring and response capabilities across the country, ensuring timely and effective interventions for stranded marine life.
Wildlife Management Marine / Ocean Conservation Environmental Health

Estelle Massey Osborne Scholarship

Nurses Educational Funds Inc.
Private
United States
Unspecified amount
The Estelle Massey Osborne Scholarship supports exceptional African American nurses pursuing master's degrees. Applicants must have at least two semesters remaining in their program, maintain a minimum GPA of 3.6, and hold a current RN license. This scholarship, provided by Nurses Educational Funds Inc., honors Estelle Massey Osborne, the first African American nurse to earn a master's degree in the U.S. It aims to promote nursing leadership through financial assistance for advanced education.
Education - Higher Education Nursing Mental Health & Psychiatric Diseases +2 more

EBBA: Research Grants

Eastern Bird Banding Association (EBBA)
Association/Society
Central America, North America +1 more
Up to US $5,000
The Eastern Bird Banding Association is offering the Memorial Fund Research Grants to support research utilizing avian marking techniques, such as banding. Applicants must submit a detailed project proposal, including significance and budget, alongside their background in ornithology. Grants are open to all, particularly encouraging student applications, with no lifetime award limit per individual. Projects must focus on species within EBBA territory, ensuring marking techniques are integral to the research.
Ornithology

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $600,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is launching a funding opportunity for Exploratory Clinical Trials Grants. This program aims to support innovative clinical trials that enhance the understanding and treatment of arthritis and other musculoskeletal and skin conditions. Research proposals should focus on early-stage trials, including first-in-human studies, dose-finding, and biomarker evaluation. The initiative encourages the translation of promising laboratory findings into effective clinical practices, ultimately improving patient outcomes.
Musculoskeletal Diseases Skin Diseases & Dermatology Arthritis

NIAMS Clinical Trial Implementation Cooperative Agreement

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
More than US $250,000
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is inviting applications for the Clinical Trial Cooperative Agreement Program. This funding opportunity supports investigator-initiated, interventional clinical trials at various phases. Initial funding will facilitate the preparation needed to start trials, with successful milestones leading to further support. NIAMS emphasizes hypothesis-driven trials that promise significant clinical impact within its research mission.
Musculoskeletal Diseases Arthritis Skin Diseases & Dermatology

Moody’s Community Impact Grant Program

Moody’s Investors Service, Inc.
Corporate
Argentina, Brazil +21 more
Unspecified amount
The Moody's Community Impact Grant Program supports organizations with tax-exempt status to foster social and economic equality. Established by Moody's Foundation, it prioritizes initiatives that empower underestimated communities and entrepreneurs, driving innovation and ecological restoration. The foundation focuses on inclusive growth, providing resources for small businesses and community resilience. Eligible organizations must be registered charities under U.S. IRS guidelines, while ineligible entities include individuals and those promoting unlawful discrimination.
Business Development Entrepreneurship Habitat & Ecosystem Restoration

Specialized Transportation Program (5310): Contracted Transportation Service Funding

Ohio Department of Transportation
State/Local Government
Adams County, Ohio, Allen County, Ohio +70 more
Unspecified amount
The Specialized Transportation Program (5310) aims to enhance mobility for seniors and individuals with disabilities through federally funded projects. This program supports various initiatives, including vehicle funding, preventive maintenance, and contracted transportation services. With an 80% federal cost coverage, local funding must cover the remaining 20%. The Ohio Department of Transportation oversees this program, ensuring accessible transportation options in urban and rural areas, thereby addressing the unique needs of transit-dependent populations.
Disability Care & Services Senior Services Rural Development +1 more

ASTRO-LUNGevity Residents / Fellows in Radiation Oncology Seed Grant

LUNGevity Foundation Inc
Private
United States
Up to US $50,000
The ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed Grant aims to enhance the research careers of residents and fellows focused on radiation oncology, specifically benefiting lung cancer patients. This initiative supports basic, translational, and clinical research endeavors. With a maximum award amount of $50,000 for one year, it provides essential funding to foster innovative projects that can lead to significant advancements in lung cancer treatment.
Cancer / Oncology Lung Cancer Biomedical Imaging

Presenter Consortium for Jazz Grant

Chamber Music America
Private
United States
Up to US $15,000
The Presenter Consortium for Jazz Grant, offered by Chamber Music America, supports U.S.-based presenters collaborating to engage professional jazz ensembles. This grant provides up to $39,000 for expenses like ensemble fees, concert production, and marketing. Each consortium can include up to three presenters and aims to enhance the jazz experience through live performances and streamed concerts. Eligible projects must involve CMA’s New Jazz Works grantees, fostering creativity and community engagement in jazz.
Chamber Music

21st Century Museum Professionals Program (2027)

Institute of Museum and Library Services
Federal Government
American Samoa, Guam +7 more
US $100,000 - US $500,000
The 21st Century Museum Professionals (21MP) Program, funded by the Institute of Museum and Library Services, aims to enhance career pathways and professional networks in the museum sector. This initiative focuses on developing current museum staff, recruiting new professionals, and fostering partnerships that promote effective workforce training. By emphasizing peer learning and alternative career pathways, the program seeks to create a robust and diverse museum workforce across the nation.
Education - Higher Education Workforce Preparation & Job Readiness Museums & Cultural Institutions +1 more

Geoff Richter Performing Arts Award

Foundation For Jewish Philanthropies
Private
United States
US $2,000

Our Mission

Empower donors to fulfill their passions and dreams by establishing charitable vehicles designed to create a positive and enduring impact on Jewish Buffalo, Western New York and the World.

Geoff Richter Performing Arts Award

The Geoff Richter Performing Arts Award Committee announces the availability of an Award up to $2,000! The GRPAA was founded in memory of Geoff Richter, Western New York Musician and Educator of the Arts.

About Geoff Richter

A native of Eden, New York, Geoff received his Bachelor of Music degree with a Performer’s Certificate in trumpet and a Master’s with a Performers Fellowship, from the Eastman School of Music.

Geoff played trumpet professionally with the Rochester, San Antonio, and Buffalo Philharmonic Orchestras and Niagara Falls, Binghamton, Chautauqua, Orchard Park, Clarence, Cheektowaga, and Amherst Symphony Orchestras. He co-founded the Buffalo Brass Quintet, the Buffalo Niagara Concert Band, and The Frankfurters, an internationally known Bavarian show band. He also acted as the summer/pops conductor of the Erie County Wind Ensemble and the Amherst Symphony Orchestra.

After retiring from a long career at Williamsville North High School, Geoff started working part time as director of the orchestra for musicals at St. Joseph Collegiate Institute. He also worked with the Mount Saint Mary Academy band and recruited and directed the orchestra for the annual school musical.

Performing Arts Education - Higher Education Music +2 more

Pathways APN Research Awards

Alkermes
Corporate
United States
Up to US $10,000

Alkermes

At Alkermes, we apply our deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders, including addiction, serious mental illness and sleep disorders. With our portfolio of marketed medicines and investigational pipeline candidates, we seek to make a meaningful difference in the way people manage these chronic diseases. Our patient-inspired science, integrated research strategy, sophisticated development capabilities and specialized commercial infrastructure enable us to pursue the development and commercialization of innovative new medicines, including those for people with conditions that have traditionally been overlooked or stigmatized.

Our greatest strengths at Alkermes are our people and our inherent empathy for patients, families and caregivers. Neurological and psychiatric disorders strike people at the core of who they are and impact many facets of their lives. We work with urgency to develop new treatment options for people living with these conditions.

Pathways APN Research Awards

The Alkermes Pathways Advanced Practice Nurse (APN) Research Awards™ program is designed to empower the advanced practice nursing community by offering funding opportunities that recognize their vital role in evidence-based care and the advancement of mental health research.

The Alkermes Pathways APN Research Awards provide opportunities for individual grants of up to $10,000 per project for licensed psychiatric-mental health nurse practitioners who are actively engaged in clinical, academic, and/or community health settings and are committed to advancing research in schizophrenia or bipolar I disorder.

Mental Health & Psychiatric Diseases Schizophrenia Nursing

Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $212,004 - US $2,725,311
This funding opportunity aims to advance HIV/AIDS research by implementing human new approach methodologies (NAMs) to reduce the reliance on specific pathogen free (SPF) animal models. It emphasizes the integration of NAMs-enabled frameworks for in vitro testing while supporting essential SPF colony resources. The initiative seeks to enhance research rigor and reproducibility through innovative strategies that prioritize human-relevant models, ultimately improving HIV research outcomes and facilitating collaborative development in the field.
HIV / AIDS

Comprehensive Suicide Prevention Program for States (363329)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $650,000 - US $1,200,000
The CDC's Comprehensive Suicide Prevention Program for States aims to enhance public health approaches to suicide prevention across the U.S. By targeting high-risk groups, such as veterans and rural populations, the program utilizes data to identify prevention areas, assess existing programs, and implement evidence-based strategies. Key outcomes include improved partner engagement and a measurable reduction in suicide rates. This initiative allows potential applicants to prepare by reviewing relevant data and forming strategic partnerships ahead of future opportunities.
Suicide Prevention

Direct-to-Consumer Distribution of HIV and other STI Self-Tests

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to enhance a web-based ordering portal for distributing 1.5 million HIV and STI self-tests to high-burden communities. By optimizing access to these self-tests, the initiative seeks to raise awareness, prevent new infections, and improve the health outcomes of users, thereby contributing to better overall public health and wellbeing.
HIV / AIDS

Syringe Service Program Grant

The Comer Family Foundation Inc
Private
District of Columbia, Puerto Rico +1 more
US $2,500 - US $20,000
The Syringe Service Program Grant, offered by The Comer Family Foundation, aims to enhance harm reduction initiatives by funding syringe access programs across the U.S. These programs provide sterile syringes, education, and support services to mitigate the risks associated with drug use, including HIV and hepatitis transmission. Priority is given to organizations in underserved areas and those led by marginalized communities. Grants are available for operational costs, program development, and staff training, with a focus on sustainability and local partnerships.
Drug Use Disorder

Fiscal Year (FY) 2027 Service Area Competition (SAC) (363777)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +7 more
US $650,000 - US $1,500,231
The FY 2027 Service Area Competition (SAC) funding aims to enhance health services in underserved communities across the U.S. by providing grants for comprehensive preventive and primary care. This initiative allows for a competitive selection of service areas, ensuring that health centers can effectively deliver high-quality healthcare. Additional service areas may be announced throughout the year to accommodate changes in service availability, supporting continuous care for those in need.
Epidemiology & Public Health Health Care Access & Delivery Preventative Healthcare +2 more

Independent Living Initiatives

Music Movement
Association/Society
United States
US $1,500 - US $5,000
Music Movement's Independent Living Initiatives grant supports individuals with Autism and developmental differences in the U.S. Grants, typically ranging from $1,500 to $5,000, aid in various areas including independent living, camps, and continued education. Applicants must be legal guardians of eligible individuals aged 18 and older. The grant portal will reopen for submissions on March 28, 2026, encouraging early review of guidelines to ensure complete applications.
Music Autism Physical Therapy

Operating Grants for Nonprofits in Ohio Highlights

Looking for operating grants for nonprofits in Ohio?


Read more about each grant below or start your 14-day free trial to see all operating grants for nonprofits in Ohio recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in Ohio

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Operating grants for nonprofits in Ohio grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

87 Operating grants for nonprofits in Ohio over $25K in average grant size

57 Operating grants for nonprofits in Ohio over $50K in average grant size

34 Operating grants for nonprofits in Ohio supporting general operating expenses

200+ Operating grants for nonprofits in Ohio supporting programs / projects

1,000+ Grants on Instrumentl focused on Mental Health & Psychiatric Diseases

700+ Grants on Instrumentl focused on Family Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Ohio?

Most grants are due in the first quarter.

Q1
28.5%
Q2
24.2%
Q3
24.9%
Q4
22.4%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Ohio?

Grants are most commonly $29,500.

$250 $250 Min.
$29,500 $29.5 K Median
$468,793 $468.8 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Ohio?

Grants are most commonly $97,851.

$97,851

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Ohio year over year?

In 2024, funders in Ohio awarded a total of 84,081 grants.

2022 78,879

2023 79,604

2024 84,081

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Ohio given out in Ohio, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Ohio changing over time?

Funding has increased by -1.54%.

2022 $7,853,771,046

2023 $8,315,467,696
5.88%

2024 $8,187,079,289
-1.54%

Ohio Counties That Receive the Most Funding

How does grant funding vary by county?

Hamilton County, Cuyahoga County, and Franklin County receive the most funding.

County Total Grant Funding in 2024
Hamilton County $3,320,115,009
Cuyahoga County $2,821,239,308
Franklin County $2,035,647,424
Summit County $545,376,601
Scioto County $393,048,909