Best Operating Grants for Nonprofits in Ohio

The Valero Energy Foundation Grants support nonprofit organizations that align with their mission to improve the quality of life in communities where Valero operates. With a focus on basic needs, health care, education, and civic initiatives, the foundation prioritizes funding requests from 501(c)(3) organizations. In 2019, it provided approximately $40 million to support disadvantaged children and families, emphasizing a commitment to corporate citizenship and community well-being.

The SHF Responsive Grant Program, offered by Sisters Health Foundation, supports projects aimed at enhancing healthy eating, active living, thriving neighborhoods, and mental health in the Mid-Ohio Valley. Eligible applicants include 501(c)(3) nonprofits and public institutions targeting specific counties in West Virginia and Ohio. The program prioritizes evidence-based strategies to promote health and well-being, foster community resources, and improve access to essential services, making it a vital resource for local organizations seeking funding.

The EQT Foundation Grant Program supports nonprofits with a focus on community enrichment, education, and environmental preservation in areas aligned with EQT Corporation's business operations. Since 2003, it has awarded over $74 million, emphasizing impactful, evidence-based proposals that foster safe and sustainable communities. Eligible organizations must be tax-exempt and demonstrate effective resource management. The foundation prioritizes projects that promote STEM education, community engagement, and conservation efforts to enhance quality of life in the regions it serves.

The Thomas J. Emery Memorial Grant, established by prominent Cincinnati philanthropists, aims to enhance the lives of individuals in the Greater Cincinnati area through grants that support social, cultural, educational, civic, and physical betterment. Founded in 1925, the grant prioritizes nonprofit organizations with IRS 501(c)(3) status, focusing on collaborative projects and impactful initiatives, while not providing ongoing operational support. This initiative honors the legacy of Thomas and Mary Emery in fostering community development.

Truist Foundation

The Truist Foundation is committed to Truist Financial Corporation's (NYSE: TFC) purpose to inspire and build better lives and communities. Established in 2020, the foundation makes strategic investments in nonprofit organizations to help ensure the communities it serves have more opportunities for a better quality of life. The Truist Foundation's grants and activities focus on building career pathways to economic mobility and strengthening small businesses.

Inspire Awards

This year’s Inspire Awards seeks nonprofits supporting the career navigation and workforce development needs of workers across the United States. The challenge seeks applications that help individuals gain the skills, guidance, and support needed to access quality jobs, advance in their careers, and build long-term stability in an evolving world of work.

2026 Truist Foundation Inspire Awards Challenge Question

How are nonprofits providing innovative direct services, training programs, and career navigation supports for adult workers in the age of AI?

Challenge Dimensions

Nonprofit organizations have long been critical advocates and service providers for workers in the United States. Nonprofits provide workers necessary upskilling opportunities, AI literacy training, career navigation support, and wraparound services in conjunction with career pathways programming. All necessary for the modern workforce. Meeting the moment, Truist Foundation and MIT Solve want to hear the ways in which nonprofits headquartered in the Truist operating footprint are providing innovative career pathway programming in the age of AI. Although solutions don’t need to focus on generative AI specifically, teams should demonstrate how their career pathways programming align with the following dimensions:

• Training and Upskilling Programs – Providing holistic, accessible programming that equips workers with essential skills, industry-validated credentials, and technical literacy for the modern workplace.
• AI Readiness and Literacy – Offering high-quality training that helps workers understand generative AI and agentic technologies as augmented intelligence tools, helping to build practical skills like effective prompting, domain expertise application, and ethical use.
• Additional Wraparound Services and Basic Needs Support – Supporting unemployed and underemployed workers on their journey to economic mobility through comprehensive, integrated resources including childcare, transportation support, mentorship, mental health services, benefits navigation, and more.
• Career Navigation in the AI Economy – Enabling workers to navigate career choices with clarity and confidence by providing accessible information about how AI is reshaping job roles and industries, facilitating informed decisions about high-quality career trajectories that align with individual circumstances, and connecting workers to industry-validated credentials or trainings.

Here are the grants for this challenge

• First place: $250,000
• Second place: $150,000
• Runners-up: $25,000
• Audience favorite: $75,000

The Elsa Heisel Sule Foundation Grant supports 501(c)(3) organizations in the Greater Cincinnati area, focusing on education, health, arts, and community welfare. Established in 2004, the foundation prioritizes projects that enhance community well-being, ensuring grants are awarded to nonprofits with operating budgets under $10 million. Organizations must apply annually and adhere to specific eligibility criteria, including geographical and operational restrictions. The foundation aims to empower local initiatives that promote positive societal impact.

The Ohio History Fund Grants: Bricks & Mortar Grant supports history-related projects through competitive matching funds. Eligible applicants include Ohio-based nonprofits and government entities, aiming to preserve historical properties and sites. Grants range from $2,000 to $20,000 with a 60/40 match requirement. Since 2013, over $1 million has been awarded across the state, highlighting significant community interest and need for historical preservation funding.

The Baltimore Life Community Grants Program, established by the Baltimore Life Foundation, awards grants of up to $500 to nonprofit organizations in various states, including Maryland and Virginia. This initiative aims to enhance community quality of life through projects that focus on family safety and community enhancement. Eligible applicants must be IRS-certified 501(c)(3) organizations, with priority given to those with volunteer support. This program reflects Baltimore Life's commitment to corporate citizenship and community involvement.

The Ruth Danley and William Enoch Moore Charitable Fund Grant is a private foundation based in Pittsburgh, established in 1992. It focuses on philanthropy, specifically supporting K-12 education for Native American children living on reservations. The foundation directs its grants primarily to regions preferred by donors, including several states in the Northeast and Midwest, aiming to improve educational opportunities and foster community development in underserved populations.

The Ridgecliff Foundation Grant Program supports nonprofit organizations focusing on mental health and chemical dependency in Northeast Ohio. This funding is aimed at education, prevention, and treatment initiatives. Eligible organizations must be tax-exempt and operate within specific counties. The foundation does not fund general operating support, construction projects, or research. Grants are limited to one per organization annually, and multi-year projects require yearly re-application.

The Penn National Gaming Foundation Grants support various community initiatives across North America, emphasizing education, health services, and cultural affairs. Launched post-Hurricane Katrina, the foundation aids local nonprofits, enhancing community development, public safety, and veteran support. The grants cater to organizations that address the needs of children, senior citizens, and disadvantaged populations, ensuring a broad impact in areas where Penn National Gaming operates. This commitment reflects the foundation's dedication to uplifting communities and fostering resilience.

The American Honda Foundation provides programmatic support to nonprofit organizations and schools in the U.S., empowering impactful initiatives aligned with community needs. Funding opportunities are available through Honda corporate and Honda USA Foundation, focusing on projects that enhance education and community welfare. Eligible organizations must have nonprofit status or be recognized educational institutions. The application process opens each fall, with funding decisions announced the following spring, ensuring alignment with Honda's commitment to social responsibility.

The Programmatic Support - Education Pillar Award by Honda aims to enhance workforce readiness in the manufacturing sector. It supports nonprofit organizations and schools focused on hands-on programs in design, software/data analytics, and AI/machine learning. Eligible applicants must be US-based and have 501(c)(3) status. The initiative prioritizes projects that train individuals for manufacturing roles, develop technical skills, and introduce automation to prepare for evolving industry demands, ultimately fostering economic prosperity in local communities.

The Environment Pillar Award by Honda supports nonprofit organizations and schools in the U.S. focused on sustainability. Grants aim to reduce environmental impact through programs in decarbonization, clean energy, and efficient resource use. Eligible projects must align with Honda's mission and primarily benefit communities where Honda associates live and work. Organizations can apply for up to two grants, provided they meet specific eligibility criteria, including tax-exempt status under the IRS.

The Honda USA Foundation's Mobility Pillar Award aims to empower individuals with disabilities by funding programs that enhance access and mobility. The foundation supports nonprofit organizations and schools that provide therapeutic, adaptive, and comprehensive care programs, as well as mobility modifications and assistive technology. Applications are accepted from U.S.-based organizations with 501(c)(3) status or fiscal sponsors, ensuring that the joy of mobility is accessible to all.

The Fifth Third Foundation offers grants to nonprofit organizations in the Greater Cincinnati area, focusing on education, arts, community development, and health services. It aims to enhance community vibrancy and provide opportunities, supporting various funding interests from several benefactors. Eligible organizations must be 501(c)(3) nonprofits operating in Cincinnati, Dayton, or Northern Kentucky. The foundation prioritizes initiatives that empower women, support children, and promote environmental conservation, among other charitable purposes.

The JBF Do Good Grant, established by the Joe Burrow Foundation, aims to support innovative projects that assist underprivileged children, particularly those facing mental health challenges and food insecurity. Eligible organizations include nonprofits and public charities, with proposals up to $10,000 considered. The foundation encourages creative solutions that foster lasting impacts within communities in Greater Cincinnati and Baton Rouge. By fostering these initiatives, the foundation continues Joe Burrow's commitment to community service and social responsibility.

The Daniel and Susan Pfau Foundation, established in 1994, focuses on enhancing education, health, cultural experiences, and social welfare for youth with disabilities and economic challenges in the Greater Cincinnati area. It supports arts organizations and recreation initiatives, prioritizing programs that help young individuals realize their potential. Eligible applicants must be recognized 501(c)(3) nonprofits and demonstrate benefits to specific counties in Ohio, Kentucky, and Indiana. The Foundation encourages collaboration with other donors for project funding.

The Elevance Health Foundation's Behavioral Health Grant aims to address significant challenges in mental health and substance use disorders. With a commitment of up to $90 million over three years, the Foundation seeks partnerships with nonprofits to enhance treatment access, promote prevention strategies, and alleviate loneliness among affected individuals. This initiative emphasizes innovative solutions and measurable outcomes, targeting both national and local programs, particularly in states with pressing health disparities.

The Community Health Foundation provides responsive grants to nonprofit organizations in Clark and Champaign Counties, Ohio, focusing on health and wellness initiatives. With a mission to preserve reproductive services and promote health equity, the foundation aims to reduce health disparities through diverse funding types, including program, project, and operating support. Grants are awarded annually to support programs addressing children's health, chronic disease management, maternal and infant health, and mental health services, fostering a healthier community for all.

The Resilient and Connected Appalachians Grant Program, offered by The Nature Conservancy, provides up to $100,000 for projects that acquire land and easements throughout the Appalachian region. This program emphasizes equitable conservation, aiming to support historically marginalized communities and enhance access to nature while addressing climate change impacts. Projects must demonstrate community engagement and align with the program's goals to protect vital habitats and foster resilience in the face of environmental challenges.

The Ohio Arts Council's ArtsNEXT program offers competitive funding for innovative and experimental projects aimed at enhancing the arts in Ohio. With awards typically up to $25,000, this grant supports bold ideas that push artistic boundaries, improve accessibility, and encourage diversity in arts experiences. Projects may include collaborations, new programming strategies, or technology advancements that foster community engagement. Organizations must demonstrate a commitment to artistic evolution and meet specific eligibility criteria to apply.

The OAC Project Support: ArtSTART program, managed by the Ohio Arts Council, offers flexible funding up to $5,000 for nonprofit organizations in Ohio. This initiative supports short-term projects that enhance community arts programming, including performances, exhibitions, and educational activities. Eligible applicants include arts organizations and educational institutions committed to arts initiatives. Notably, funds cannot be used for fundraising or hospitality expenses, ensuring that financial support directly benefits artistic endeavors.

The AmeriHealth Caritas Foundation Grant aims to prevent and mitigate adverse childhood experiences (ACEs) to promote healthier outcomes for children. With a focus on empowering families, healing behaviors, and access to healthcare, the foundation supports nonprofit organizations that provide comprehensive care and resources. Grants range from $100,000 to $250,000, totaling up to $1.945 million for project-specific initiatives. Eligible organizations must be 501(c)(3) nonprofits operating in states where AmeriHealth Caritas Medicaid markets exist.

The Donald C. and Laura M. Harrison Family Foundation, established in 2006, aims to enhance educational opportunities for underprivileged students in the Greater Cincinnati area. With a focus on innovative programs and scholarships, the foundation supports initiatives in primary, secondary, and adult education. Grants range from $5,000 to $15,000 annually, promoting sustainability and collaboration with other donors. Eligible applicants must be IRS-designated 501(c)(3) organizations, prioritizing local community impact.

The Andersons Fund Supporting Organization aims to enhance the quality of life for individuals and families in northwest Ohio and southeast Michigan, particularly in the greater Toledo area. It supports nonprofit organizations with grants for programs in education, social services, mental health, urban affairs, natural resources, and the arts. The Fund prioritizes capital projects and evaluates the financial stability and operational issues of requesting organizations.

The Elevance Health Foundation's Food as Medicine Grant aims to enhance access to nutritious foods and improve health outcomes for individuals facing diet-related conditions. This initiative invites qualified nonprofits to submit proposals focused on scalable solutions that address food insecurity and promote health equity. The foundation prioritizes programs that demonstrate measurable outcomes and support whole-person health, particularly for populations at high social risk. Grants will be awarded for a term of 1-3 years, with funding based on program needs.