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Best Shelby County Grants for Nonprofits in Illinois

Looking for grants for 501(c)(3) nonprofit organizations working in Shelby County, Illinois? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

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$3.48B

Total funding

$5K

Median grant

9,000+ grants
$3.48B total
$5K median

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9,245 Results based on applied filters

NIOSH Exploratory/Developmental Grant Program (R21) (363327)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $300,000
The NIOSH Exploratory/Developmental Grant Program (R21) aims to enhance understanding of occupational diseases and injuries. It focuses on identifying risks, developing prevention strategies, and translating scientific discoveries into effective measures. Applicants are encouraged to describe the health burdens addressed, outline research activities, and demonstrate potential impacts on occupational safety. This initiative supports innovative concepts, model systems, and technologies that can significantly improve workplace health outcomes.
Occupational Health & Safety

Teaching Health Center Graduate Medical Education (THCGME) Program (363324)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $160,000 - US $960,000
The Teaching Health Center Graduate Medical Education (THCGME) Program aims to equip residents with the skills to deliver exceptional healthcare, especially in rural and underserved areas. By funding the training of residents in HRSA-supported primary care residency programs, it fosters a diverse healthcare workforce capable of meeting the needs of various populations. This initiative not only enhances the quality of care but also strengthens community health systems.
Medical Education & Professional Training Rural Health Care

Direct-to-Consumer Distribution of HIV and other STI Self-Tests

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to enhance a web-based ordering portal for distributing 1.5 million HIV and STI self-tests to high-burden communities. By optimizing access to these self-tests, the initiative seeks to raise awareness, prevent new infections, and improve the health outcomes of users, thereby contributing to better overall public health and wellbeing.
HIV / AIDS

Early Detection, Response, and Control of Global Rabies Outbreaks and Associated Threats to America's Dog-Rabies Free Status

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $150,000 - US $400,000
This funding opportunity aims to enhance the global response to rabies through innovative, cost-effective tools. The initiative focuses on reducing human rabies cases and advancing canine rabies elimination, particularly in high-burden regions. Research areas include tracking vaccination efforts, managing rabies exposure investigations, improving laboratory systems, and assessing the economic impact of interventions. Ultimately, it seeks to develop strategies that protect public health and ensure the sustainability of rabies-free status in the U.S.
Infectious & Parasitic Diseases

Comprehensive Suicide Prevention Program for States (363329)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $650,000 - US $1,200,000
The CDC's Comprehensive Suicide Prevention Program for States aims to enhance public health approaches to suicide prevention across the U.S. By targeting high-risk groups, such as veterans and rural populations, the program utilizes data to identify prevention areas, assess existing programs, and implement evidence-based strategies. Key outcomes include improved partner engagement and a measurable reduction in suicide rates. This initiative allows potential applicants to prepare by reviewing relevant data and forming strategic partnerships ahead of future opportunities.
Suicide Prevention

Statewide Perinatal Quality Collaboratives: Improving Perinatal Care and Outcomes

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Statewide Perinatal Quality Collaboratives initiative aims to enhance the health of pregnant and postpartum women and their newborns through quality improvement strategies. Funded by the CDC, the program encompasses two components: state-based Perinatal Quality Collaboratives and a National Network coordinating center. Key strategies include strengthening data systems and fostering partnerships to improve healthcare services and outcomes. Ultimately, this initiative seeks to implement successful quality improvement initiatives that ensure better coordination and health outcomes for mothers and newborns across the United States.
Maternal And Perinatal Health

Cherokee Nation Allied Health Scholarship

Cherokee Nation Foundation
Association/Society
United States
Unspecified amount

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Cherokee Nation Allied Health Scholarship

The purpose of the Cherokee Nation Allied Health Scholarship is to provide financial assistance to Cherokee Nation citizens pursuing college degrees in health care fields to support their readiness to contribute to and grow within the Cherokee Nation reservation labor market. This scholarship is competitive and subject to availability of funding.

The foundation also offers a Nursing Scholarship and if funding allows, scholarships will be available for degrees in health fields other than nursing to meet any current workforce need in the Cherokee Nation Health Services department.

Education - Higher Education Health & Medicine Academic Scholarship Programs

Jessica Lynn Herman Memorial Scholarship

Orange County Community Foundation
Private
United States
Unspecified amount

Scholarship funds are established by local individuals, families, businesses and organizations. They provide tuition assistance and financial support to new and continuing college students, and many offer renewable awards.

Jessica Lynn Herman Memorial Scholarship

Graduating high school senior from the Huntington Beach High School District with a passion for both the sciences and humanities and demonstrated commitment to mentoring or tutoring. 

Humanities & Social Science Education - Higher Education Career / College Preparation

Research Grant Program

IMMUNE DEFICIENCY FOUNDATION
Private
United States
US $25,000 - US $50,000

Research Grant Program 

Providing research grants to support clinicians and scientists focused on primary immunodeficiency (PI).

Scope and eligibility

  • The Immune Deficiency Foundation's Research Grant Program supports patient-centered research focused on improving the treatment, health, disease management, or diagnosis of people with primary immunodeficiency (PI), as well as research that contributes to the broader body of knowledge on PI.
  • Awards range from $25,000-50,000. In addition, the Michael Blaese Research Grant Award is bestowed on the highest-scored application each cycle.
  • One-year term.
Immune System Diseases Lupus

Engineering (ENG): Civil, Mechanical and Manufacturing Innovation (CMMI)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Science Foundation (NSF) is offering funding through the Engineering (ENG) program, focusing on foundational research in civil, mechanical, and manufacturing innovation. Key areas include advanced manufacturing systems, civil infrastructure, and intelligent dynamic systems. The NSF ENG encourages innovative and transformative proposals that may not require immediate commercial outcomes. Award sizes and durations will vary based on budget availability, aiming to support long-term research advancements.
Engineering Manufacturing Engineering Mechanical Engineering

Dairy Business Innovation Initiatives Program (DBI) Fiscal Year 2026

USDA: Agricultural Marketing Service (AMS)
Federal Government
United States
US $2,300,000 - US $3,450,000
The Dairy Business Innovation Initiatives Program (DBI) for Fiscal Year 2026, administered by the USDA's Agricultural Marketing Service, invites applications from existing initiatives to support the dairy industry. With approximately $12.65 million available, the program aims to diversify dairy markets, enhance farmer income, and promote regional milk production. Funding will prioritize equipment and infrastructure projects, which are vital for strengthening the capacity of dairy businesses and fostering innovation in processing and marketing.
Agriculture Agricultural Economics Business Development

WATER RESOURCES RESEARCH ACT PROGRAM NATIONAL COMPETITIVE GRANTS FY2026 (104g General)

US Department of the Interior: Geological Survey (USGS)
Federal Government
American Samoa, Guam +5 more
Up to US $120,000
The Water Resources Research Act Program National Competitive Grants FY2026, administered by the U.S. Geological Survey, aims to support innovative research initiatives at Water Resources Research Institutes across the U.S. and its territories. These grants facilitate essential studies on water management, addressing critical water resource challenges while promoting collaboration among states. This program seeks to enhance the understanding of water issues, ultimately contributing to sustainable management practices and informed decision-making in water resource policy.
Hydrology Freshwater Conservation Environmental Policy

Fiscal Year 2026 Wildlife Crossings Pilot Program

DOT Federal Highway Administration
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Fiscal Year 2026 Wildlife Crossings Pilot Program aims to enhance public safety by reducing wildlife-vehicle collisions and improving habitat connectivity for various species. With approximately $80 million available through cost reimbursable grants, this initiative supports eligible projects that address these critical environmental and safety concerns. The program may also distribute leftover funds from previous years, contingent on availability, fostering innovative solutions in wildlife management and transportation safety.
Land / Habitat Conservation Community / Public Safety Wildlife Health +1 more

The Science, Mathematics and Research for Transformation (SMART) Scholarship for Service Program Cooperative Agreement

US DOD: Office of the Secretary of Defense
Federal Government
American Samoa, Guam +4 more
US $1,300,000,000
The SMART Scholarship-for-Service Program, managed by the Department of War, aims to enhance the U.S. military's technical workforce by offering competitive scholarships for STEM degrees. With a funding cap of $1.3 billion over ten years, the program prepares scholars for critical roles in national defense, ensuring a pipeline of skilled professionals. Since its inception in 2005, over 8,000 scholarships have been awarded, fostering a strong connection between education and service in defense-related fields.
Education - Higher Education Workforce Preparation & Job Readiness STEM / STEAM Education

Small Business Innovation Research and Small Business Technology Transfer Programs Phase II (364020)

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
American Samoa, Guam +4 more
US $600,000 - US $650,000
The USDA SBIR/STTR programs aim to enhance scientific excellence and technological innovation through federal funding, fostering a robust national economy. By supporting small businesses in addressing federal research needs, these programs encourage the commercialization of federally funded research. Specifically, the STTR program promotes partnerships between small businesses and research institutions, such as universities and federal laboratories, to advance cooperative research and development efforts.
Entrepreneurship Economic Services & Development Emerging Technology Development +1 more

Technical Assistance and Training Grant Program (364019)

USDA: Rural Utilities Service (RUS)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Technical Assistance and Training Grant Program by the USDA's Rural Utilities Service provides funding for essential technical assistance and training aimed at resolving water and waste management issues. This program supports applicants in preparing loan and grant applications, enhancing the operational efficiency of water systems, and ensuring compliance with best practices in facility management. However, grant funds cannot be used for duplicating existing services or for capital expenditures.
Rural Development Public Infrastructure Fish Conservation

Solid Waste Management Grant Program (364018)

USDA: Rural Utilities Service (RUS)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Solid Waste Management Grant Program, administered by the USDA's Rural Utilities Service, invites applications for FY 2027 funding. This initiative aims to enhance solid waste management in rural communities through technical assistance and training. Eligible organizations can receive grants to develop sustainable waste management practices, addressing critical issues like water pollution and emerging contaminants, while promoting hazardous waste collection. This program supports operational improvements and capital financing applications to ensure long-term environmental health.
Freshwater Conservation Environmental Contamination & Pollution Environmental Health +1 more

HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HIV Prevention and Alcohol R61/R33 funding opportunity aims to advance innovative HIV prevention strategies through a phased research approach. The R61 phase focuses on developing and pilot testing interventions, addressing key implementation questions for diverse populations. Following successful milestones, the R33 phase expands testing of these interventions and explores their effectiveness and sustainability, particularly in relation to alcohol use and related health issues.
Infectious & Parasitic Diseases HIV / AIDS Preventative Healthcare

ROSES 2025: A.18 Geosphere

National Aeronautics and Space Administration (NASA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NASA ROSES 2025: A.18 Geosphere program provides funding for research on solid-Earth processes across various scales. It aims to enhance understanding of the Earth's structure and dynamics, particularly in the core, mantle, and lithosphere. Key areas of focus include Earth Surface Properties, Crustal Dynamics, and Earth Interior. This initiative supports advancements in managing natural resources, assessing geohazards, and exploring the forces driving plate tectonics, ultimately contributing to improved hazard forecasting and mitigation strategies.
Earth Science Geology Disaster Preparedness

Distressed Cities Technical Assistance (DCTA) Program for Fiscal Years 2026 and 2027

US HUD: Office of Community Planning and Development (CPD)
Federal Government
American Samoa, Guam +4 more
US $400,000 - US $3,000,000
The Distressed Cities Technical Assistance (DCTA) Program provides competitive funding for eligible applicants to deliver technical assistance to local governments serving economically distressed communities of 50,000 or fewer residents. Selected awardees collaborate closely with HUD to enhance the capabilities of UGLG officials and staff, ensuring they effectively address community needs. Applicants may focus on broad HUD jurisdictions or specific areas as specified in the program's NOFO.
Economic Services & Development Community Development & Revitalization Rural Development

Unlocking Value and Opportunities from Carbon Flows in Water Utilities RFP

Water Research Foundation
Private
Canada, United States
Up to US $300,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5430 - Unlocking Value and Opportunities from Carbon Flows in Water Utilities

Grant Information

  • Identify carbon flows across drinking water, stormwater, wastewater, and advanced treatment systems. Carbon flows may include source water, stormwater, process emissions, process inputs, residuals, and biogas.
  • Identify the most relevant carbon recovery, capture, conversion, storage, and avoidance opportunities.
  • Evaluate value creation pathways, including products, avoided costs, and environmental attributes, and mechanisms and partnerships needed to put them into practice.
  • Assess how opportunities vary across system types and local contexts by focusing on more common scenarios for utilities.
  • Provide practical, research-based insights to support identification, prioritization, evaluation, and advancement of carbon management opportunities under site-specific conditions and constraints.
  • Evaluate implications for greenhouse gas (GHG) accounting, environmental attribute claims, and other potential benefits across pathways.
Water Resource Management Carbon / Greenhouse Gas Reduction Green Infrastructure

Practical Playbook for Adaptive Utility Capital Improvement Planning Under Deep Uncertainty RFP

Water Research Foundation
Private
Countries
Up to US $250,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5411 - Practical Playbook for Adaptive Utility Capital Improvement Planning Under Deep Uncertainty

Grant Information

  • Assess current utility practices for incorporating adaptive or flexible decision making into capital improvement planning (CIP) at the portfolio or programmatic level.
  • Identify where deep uncertainty most affects CIP decision points, including investment areas prone to lock-in or points of no return.
  • Document the institutional processes, frameworks, and governance structures that have enabled utilities to embed adaptive and flexible investment strategies.
  • Quantify how adaptive capital strategies compare to traditional CIP approaches in terms of lifecycle costs, rate stability, financial risk exposure, and avoided or deferred capital investments across a range of plausible future conditions.
  • Establish practical criteria to help utilities determine which types of capital investments are well suited for adaptive approaches.
  • Develop a practitioner-focused playbook that equips utilities to apply adaptive CIP in practice, including case studies, decision trees, trigger points, vulnerability assessment tools, financial and risk insights, and governance guidance.
  • Produce tiered recommendations that allow utilities to adopt adaptive CIP practices incrementally.
Water Resource Management Environmental Policy

Optimizing PFAS Treatment Systems for Multi-contaminant Removal and Operational Benefits RFP

Water Research Foundation
Private
Countries
Up to US $450,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5418 - Optimizing PFAS Treatment Systems for Multi-contaminant Removal and Operational Benefits

Project Objectives

Environmental Contamination & Pollution Water Resource Management Carbon / Greenhouse Gas Reduction

Investigation of Non-Point Sources of PFAS in Sewersheds and Potential Mitigation Strategies RFP

Water Research Foundation
Private
Countries
Up to US $250,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5426 - Investigation of Non-Point Sources of PFAS in Sewersheds and Potential Mitigation Strategies

Grant Information

  • Evaluate the impact of non-point or dispersed sources of per- and polyfluoroalkyl substances (PFAS) in the sewershed (including PFAS-contaminated groundwater infiltration) on PFAS mass loading to wastewater treatment plants.
  • Assess how PFAS loading from non-point or dispersed sources of PFAS in the sewershed may affect treatment efficiency and reuse water quality.
  • Improve understanding of PFAS precursor contributions.
  • Identify potential strategies to mitigate PFAS loading from non-point or disbursed sources of PFAS in the sewershed.
  • Water Resource Management Sanitation & Clean Drinking Water

    Innovative Approaches to Extend Lifetime and Minimize O&M for Nature-based Installations RFP

    Water Research Foundation
    Private
    Countries
    Up to US $250,000

    About Us

    advancing the science of water ®

    Who We Are

    The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

    5416 - Innovative Approaches to Extend Lifetime and Minimize O&M for Nature-based Installations

    Grant Information

    • Identify and evaluate innovative design, construction, and management approaches that extend the functional lifetime of nature-based installations and reduce ongoing operations and maintenance (O&M) requirements.
    • Develop practical guidance on key factors affecting nature-based solution (NbS) longevity, including hydraulic optimization, engineered media selection and replacement, plant selection, sediment management, and construction-phase best practices.
    • Survey utilities and other NbS owners to document current maintenance practices, costs, and hours, and establish benchmarks to inform targets for improvement.
    Hydrology Climate Change Resilience & Equity Green Infrastructure +1 more

    Guidelines to Develop Best-In-Class Maintenance Strategies for Vertical Assets RFP

    Water Research Foundation
    Private
    Countries
    Up to US $250,000

    About Us

    advancing the science of water ®

    Who We Are

    The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

    5415 - Guidelines to Develop Best-In-Class Maintenance Strategies for Vertical Assets

    Grant Information

    • Develop a clear understanding of the background and benefits associated with implementing well-rounded maintenance strategies for vertical assets.
    • Develop a structured approach to identify and implement best-in-class maintenance strategies for vertical assets that improve reliability, increase asset availability, reduce unplanned work and emergency shutdowns, support the transition from reactive to proactive maintenance, and minimize total lifecycle cost.
    • Apply leading practices such as Reliability Centered Maintenance (RCM) and cutting-edge technologies and analytics to vertical assets.
    Water Resource Management

    Bioavailability and Transformation of Dissolved Organic Nitrogen and Phosphorus Across WRRFs RFP

    Water Research Foundation
    Private
    North America
    Up to US $275,000

    About Us

    advancing the science of water ®

    Who We Are

    The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

    5429 - Bioavailability and Transformation of Dissolved Organic Nitrogen and Phosphorus Across WRRFs

    Project Objectives

    • Survey and characterize dissolved organic nitrogen and phosphorus (DON/DOP) concentrations and speciation across North American wastewater facilities, including but not limited to influent, secondary effluent, tertiary effluent, digester supernatant, thermal hydrolysis process (THP) centrate, autothermal thermophilic digestion (ATAD) sidestreams, and dewatering recycle streams.
    • Understand the dynamics of DON/DOP in effluent, including quantifying the bioavailable fraction of DON/DOP in different relevant process streams, evaluating their transformation into nitrogenous disinfection by-product (N-DBP) precursors, determining bio-uptake rates representative of receiving water conditions, and measuring the timescale for biodegradation in receiving waters.
    Water Resource Management Hydrology

    Shelby County Grants for Nonprofits Highlights

    Looking for Shelby County grants for nonprofits?


    Read more about each grant below or start your 14-day free trial to see all Shelby County grants recommended for your specific programs in Illinois.

    Last updated: November 2, 2026. Next update: December 6, 2026.

    Grant Insights : Grant Funding Trends in Illinois

    Average Grant Size

    What's the typical amount funded for Illinois?

    Grants are most commonly $104,222.

    $104,222

    Total Number of Grants

    What's the total number of grants in Shelby County Grants for Nonprofits year over year?

    In 2024, funders in Illinois awarded a total of 104,158 grants.

    2022 97,582

    2023 97,805

    2024 104,158

    Top Grant Focus Areas

    Among all the Shelby County Grants for Nonprofits given out in Illinois, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

    1. Education

    2. Philanthropy, Voluntarism & Grantmaking Foundations

    3. Human Services

    Funding Over Time

    How is funding for Shelby County Grants for Nonprofits changing over time?

    Funding has increased by 16.08%.

    2022 $8,503,243,276

    2023 $9,316,300,812
    9.56%

    2024 $10,813,952,832
    16.08%

    Illinois Counties That Receive the Most Funding

    How does grant funding vary by county?

    Cook County, Lake County, and Macon County receive the most funding.

    County Total Grant Funding in 2024
    Cook County $6,893,460,213
    Lake County $720,580,526
    Macon County $544,478,272
    Champaign County $541,704,331
    Dupage County $496,099,366

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