Best Grants for 501(c)(3) in South Carolina

The FY26 Vision Research Program's Investigator-Initiated Research Award (IIRA) offers funding for innovative research addressing eye injury and visual dysfunction due to military exposure. This award supports preclinical to early translational studies aligned with specific focus areas. Unique features include two funding levels and a Partnering Principal Investigator Option. Applications undergo rigorous peer review based on research rationale, strategy, and impact, with potential for sharing with the National Eye Institute for additional funding consideration.

The Traumatic Brain Injury Model Systems Centers aim to enhance TBI rehabilitation through evidence-based research. These centers focus on generating knowledge to improve health, community participation, and employment outcomes for TBI individuals. Funded by the US HHS Administration for Community Living, the grants support site-specific and collaborative research, contributing to a longitudinal database. Each center can receive varying funding amounts, depending on eligible database participants, with a project timeline of 60 months comprising five 12-month budget periods.

The FY26 Vision Research Program Clinical Trial Award supports the swift execution of clinical trials aimed at improving treatments for service-connected eye injuries and visual dysfunction. This award emphasizes the need for regulatory compliance, including IND/IDE submissions, and requires documentation confirming the application's active status by March 1, 2027. Review criteria focus on clinical impact, research feasibility, recruitment strategies, and ethical considerations, ensuring relevance to military health.

The DoW Vision Research Program's FY26 Translational Research Award aims to accelerate the development of innovative drugs, devices, or clinical guidelines ready for clinical trials. It supports preclinical studies and pilot trials, ensuring alignment with specified VRP Focus Areas. Key features include a requirement for regulatory expertise in drug/device development and a unique Partnering Principal Investigator option. Review criteria focus on research rationale, strategy, feasibility, and impact, enhancing military health outcomes.

About NCCF

For more than 50 years, NCCF has been taking on tough problems to improve the quality-of-life in Northwest CT by supporting nonprofits that speak to the charitable passions of our generous donors.

NCCF is a Community Foundation, a tax-exempt public charity that enables donors to establish funds that support the work of local nonprofits through grants and provide scholarships to local students.

NCCF's Board and Staff champion the causes you care about with smart grant-making designed specifically to adapt over time and provide highly attentive, knowledgeable, and compassionate service that brings donors and organizations together to address community issues.

Scholarship Opportunities and Applications

Through the generosity of fundholders and donors, NCCF has awarded more than half a million dollars in scholarships to assist students in Northwest Connecticut with the cost of higher education.

Michele Farley Pittler Scholarship

• Academic Focus: Unspecified
• Award Average: $1,000

The Mae Casali Bonvicini Scholarship, offered by the Northwest Connecticut Community Foundation, supports Torrington High School graduating seniors aiming for higher education. With awards ranging from $400 to $1,500, this scholarship is designed to ease financial burdens for students who are U.S. citizens or permanent residents in the NCCF’s service area. For over 50 years, NCCF has dedicated itself to enhancing the quality of life in Northwest Connecticut through grants and scholarships.

The Edward W. Diskavich Scholarship, established by the Northwest Connecticut Community Foundation, honors the legacy of Edward W. Diskavich. It aims to support students from Oliver Wolcott Technical High School who are U.S. citizens or permanent residents in the service area. With awards ranging from $300 to $1,000, this scholarship helps alleviate the financial burden of higher education for deserving students, reflecting NCCF's commitment to enhancing community well-being through accessible educational opportunities.

The Pathway to Stop Diabetes Initiator Award (INI) aims to support early career researchers in diabetes research by providing funding and mentorship. With a focus on innovative and transformational ideas, this initiative encourages researchers to develop groundbreaking solutions for diabetes prevention and management. The award offers up to $100,000 annually in Phase 1 and $325,000 in Phase 2, fostering a new generation of leaders committed to improving the lives of those affected by diabetes.

The Early Career Research Programs: 'A' Award Grant by Alex's Lemonade Stand Foundation aims to support promising early career scientists in pediatric oncology. This grant fosters innovation in childhood cancer research by funding original projects that are not currently financed. Applicants must demonstrate a commitment to pediatric cancer investigation and provide a solid career development plan with mentorship. The funding can reach up to $800,000 over four years, with a maximum of $200,000 available annually.

The McKnight Clinical Translational Research Scholarship supports young investigators focusing on cognitive aging and age-related memory loss. Funded by the McKnight Brain Research Foundation, this scholarship offers $65,000 annually for two years, plus an education stipend. Eligible applicants should have completed their PhD or residency within the last five years and conduct their research in accredited U.S. institutions. The award emphasizes rigorous training and aims to foster careers in human cognitive aging research.

The Zachary Adam Giordan-Lascari Memorial Scholarship, offered by the Community Foundation of Southern New Mexico, supports fathers pursuing physical therapy education at accredited institutes. This scholarship aims to assist students from diverse backgrounds, including those with disabilities and members of the LGBTQIA+ community. With a focus on community impact, this fund exemplifies the Foundation's commitment to enhancing educational opportunities and fostering a thriving future for recipients in Southern New Mexico.

The Alzheimer’s Foundation of America Bi-Annual Grant aims to support nonprofit organizations in their efforts to enhance the lives of individuals impacted by Alzheimer’s disease and related dementias. Each grant, valued at $6,000, is awarded twice a year, focusing on innovative programs and services. AFA emphasizes partnership and collaboration, enabling grantees to manage their own policies and programs while adhering to specific funding guidelines. This initiative underscores AFA's commitment to compassionate care and ethical standards.

The RFA: Biology to Prevention Award (CRUK) aims to foster innovative translational research that enhances understanding of cancer biology, ultimately leading to effective prevention strategies. Joint applications from UK and US research teams are encouraged, with a focus on equal partnerships and complementary expertise. The funding provides up to £600,000 for UK costs and up to $946,000 for US costs, supporting projects of 1 to 5 years duration that address critical research questions in cancer prevention.

The BJA FY 2026 Emmett Till Unsolved Civil Rights Crimes Act Program aims to assist state, local, and tribal law enforcement agencies in investigating and prosecuting civil rights offenses that resulted in death before December 31, 1979. This funding opportunity is part of the DOJ's broader commitment to enhance public safety, protect civil rights, and ensure justice for victims of violent crime. Applications are due on November 20, 2026.

The Exhibitions Abroad Support Grant Program, initiated by the Japan Foundation in New York, offers financial aid to U.S. museums and art institutions organizing exhibitions that showcase Japanese art and culture internationally. This program supports a range of events, including biennials and triennials featuring Japanese artists. Eligible applicants are non-profit organizations from designated states, with a focus on promoting cultural exchange and understanding through art.

The REI Cooperative Action Fund Grant supports U.S.-based organizations that align with its mission to serve communities, particularly those connecting historically excluded individuals to the outdoors. The fund prioritizes initiatives that promote equitable access to outdoor spaces, enhance community health through nature, and create inclusive outdoor experiences. Eligible applicants must have a 501(c)(3) status and demonstrate a commitment to these values. However, individuals and certain organizations are not eligible for funding.

Nearly a decade ago, HCLTech Grant was launched by the HCLFoundation to enable cross-sector collaboration and empower non-governmental organizations (NGOs) to play a decisive role in building a stronger, future-ready India. Today, HCLTech Grant has invested nearly $18 million in groundbreaking projects and is recognized as one of the largest grant programs in India—impacting over 27,000+ villages across 22 states and 2 UT's

HCLTech Grant for Climate Action in Americas Edition III

The future of cross-sector climate collaboration

We’re proud to bring our learnings and innovations from India to the Americas. As part of our global CSR strategy, we’ll start by investing $5 million over five years to impact-focused, Americas-based NGOs to supercharge their replicable, scalable and sustainable climate action projects. As a $13.7 billion technology company with over 218,000 people worldwide, our mission is to bring together the best of technology and people to supercharge progress for our clients, our people, our communities and our planet.

We’re looking to supercharge innovative, replicable, scalable and sustainable climate solutions. If the work you do fits the following criteria, our mission is to amplify your impact:

Prerequisites

• The organization’s bylaws should expressly permit engagement in purpose-driven projects and, where relevant, climate action initiatives, in accordance with the legal regulations of the country of registration.
• The proposed project must be designed for direct implementation by the applicant organization. Sub-granting of HCLTech funds is not allowed.
• The grant amount must not be used solely for infrastructure development / purchase of fixed assets like land, buildings, and vehicles, among others. Further, proposed infrastructure development costs must be spent in line with project objectives and activities defined.
• The applicant organization, including its governing body members, must not have any pending litigations.
• The applicant organization must not be blacklisted by any government agency, department, ministry, donor or international agency.
• The organization must not have faced cancellation of its license, registration or membership from the country-specific regulatory or statutory body.
• The applicant organization or its board members or employees must not have any political or religious affiliations.

Three organizations will be selected each year—first place will receive $500,000 and two runners-up will receive $250,000 each for a two-year project.

The DoW Military Burn, Patient-Centered Research Award aims to enhance the implementation of burn care research into clinical practice for military settings. The FY26 program supports clinical trials and research that directly benefit burn patients in resource-limited environments, fostering collaborations between experienced researchers and junior scholars. This initiative addresses critical gaps in combat burn care, ensuring effective interventions and guidelines are developed and utilized in operational battlespaces.

The FY26 Military Burn Research Program (MBRP) Discovery Award aims to support groundbreaking research in combat-relevant burn care. This award encourages innovative and exploratory studies that provide new insights and foundational data for future clinical research. The focus is on novel approaches that lay the groundwork for scientific advancements and product development in burn care, ensuring robust preliminary data generation for subsequent research initiatives.

The FY26 Military Burn Research Program (MBRP) Technology/Therapeutic Development Award (TTDA) aims to translate promising preclinical findings into burn products for clinical use in challenging environments. This award supports the development of both tangible products, like medical devices, and knowledge products that enhance health outcomes. A new Mentorship Option encourages collaboration between experienced researchers and junior scientists, fostering the next generation of leaders in military burn care research.

The AE Foundation Community Grants aim to support US and Canadian non-profit organizations focused on enhancing the mental health and well-being of young people. By funding local programs, the AE Foundation empowers teens and young adults to embrace authenticity and build a brighter future. Eligible organizations must be certified 501(c)3 non-profits or registered charities, and grant funding should be utilized within 365 days of receipt. This initiative reinforces the importance of mental health in today's society.

About All Points North Foundation

All Points North Foundation is dedicated to navigating communities upward.

All Points North Foundation was founded in 2011 by a family who believes passionately that everyone has a “true North” – a place of achievement – and that everyone should have equal opportunity and access to realize their goals.

Our Vision

We envision a nation where the middle school years are seen as an important, vital time in the lives of youth, and where the public middle school education experience in underserved communities measurably improves

We also envision a nation where the integration of solar benefits families, local economies and the environment.

Our Priorities

All Points North Foundation funds grantees in two areas – public middle school education (grades 6-8) and solar – that have the power to help communities nationwide navigate upward.

Grant Making

All Points North Foundation seeks collaborative partnerships with grantees in our two priority areas.

Education

All Points North Foundation is one of the few foundations focused on public middle school education, defined as grades six through eight. We recognize the vital importance of the middle school years in shaping the future of our nation’s youth.

All Points North Foundation seeks to measurably improve public middle school education in underserved communities, whether urban or rural, through two priorities:

• Funding programs that prepare and retain middle school teachers in an ever-changing education climate.
• Helping students grow both academically and socially/emotionally.

Middle schoolers need a nurturing school environment and expertly trained, passionate teachers who can help foster academic, social and emotional growth.

It’s critical for teachers to be adequately prepared for rapidly changing classrooms and school environments, and to be continuously encouraged and inspired to serve as key role models for middle school students.

It’s also critical for middle school students to be inspired and engaged, and excited to embrace the path of learning ahead. Research clearly indicates the habits and patterns set in middle school forecast success for students in their high school years and beyond.

The Field Initiated Projects Program aims to foster new research and develop solutions that enhance the inclusion and independence of individuals with disabilities. This initiative focuses on generating scientific knowledge and understanding critical issues faced by these populations, particularly those with significant support needs. With a total of 16 grants available over a 36-month period, this program encourages innovative approaches that support employment, living arrangements, and caregiver involvement.

The Christina Sue Lilja Resource Grants support agricultural literacy by providing funds for educators to purchase resources from the Ag Foundation store. In 2025, 100 educators will receive $100 in store credits, selected randomly if applications exceed this number. This initiative, backed by the CSL Foundation, honors Christy Lilja's legacy of advocating for agricultural education. The grants aim to enhance classroom resources and improve students' understanding of agriculture, ensuring access to accurate information.

The Gender Justice Organizing Fund Grant supports initiatives led by women, girls, trans, gender nonconforming, and LGBTQI+ individuals to achieve gender justice. Organizations must prioritize community organizing and demonstrate an understanding of systemic oppression. Grants from the Bread & Roses Community Fund are crucial for groups that lack traditional funding due to their commitment to amplifying marginalized voices. The fund emphasizes long-term strategies that foster sustainable social change in the Philadelphia area.

Our Mission

The Mission of Kids Chance of Nebraska is to provide financial support to further the education of the children of Nebraska workers who have been severely injured, totally disabled or killed as a result of employment related injuries or occupational diseases. It is the goal of Kids’ Chance of Nebraska to make a difference in the lives of these children by providing scholarships to help eligible students achieve both their educational goals and their families’ dreams.

Scholarship Application Process

Kids’ Chance of Nebraska (KCNE) provides college scholarships to the children of Nebraska workers who have been severely or fatally injured in a workplace-related accident. KCNE awards as many scholarships as the current year’s funding will allow.

We open our application portal twice a year, Fall and Winter.

The Pediatric Cancer Research Foundation (PCRF) is dedicated to funding innovative research aimed at curing childhood cancer. With a focus on collaborative efforts, PCRF has contributed over $51 million since 1982, significantly improving survival rates for childhood cancers. The Translational Research Grant supports cutting-edge clinical trials and therapeutic approaches, enhancing the journey from laboratory discoveries to patient care. This initiative underscores the urgent need for effective treatments, offering hope for children diagnosed with cancer and their families.