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Best Grants for 501(c)(3) in South Carolina

Find the perfect Grants for 501(c)(3) in South Carolina on Instrumentl. 9,000+ Grants for 501(c)(3) in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,451 Results based on applied filters

Girls Flag Grant

USA Football
Association/Society
United States
Unspecified amount
The Girls Flag Grant, offered by USA Football, aims to empower youth and scholastic organizations to establish girls-only flag football programs. This inclusive initiative provides tailored support, including equipment, playbooks, and marketing resources. With a commitment to fostering growth in the sport, each grant is customized to meet the unique needs of the organization, ensuring long-term success and engagement in the game. Organizations must enroll with USA Football to apply.
Women & Girl Services Football

Shanna Stoffer Memorial Scholarship

Ashland County Community Foundation
Private
United States
Unspecified amount
The Shanna Stoffer Memorial Scholarship, offered by the Ashland County Community Foundation, aims to support Ashland County residents pursuing degrees in Education. Eligible applicants include graduating high school seniors, continuing college students, and non-traditional students with a minimum GPA of 2.5. This scholarship provides financial assistance to those enrolled or planning to enroll in two or four-year colleges or graduate programs, fostering educational advancement in the community.
Career / College Preparation Academic Scholarship Programs

Northern Lowcountry Grants: Lowcountry Unity Fund

Coastal Community Foundation of South Carolina
Private
Berkeley County, South Carolina, Charleston County, South Carolina +1 more
Approximately US $3,200
The Northern Lowcountry Grants: Lowcountry Unity Fund, established by the Coastal Community Foundation, aims to address systemic racism and economic inequality in Charleston, Berkeley, and Dorchester counties. Following the tragic 2015 attack on Emanuel A.M.E. Church, the fund provides mini-grants up to $5,000 to nonprofits promoting collaborative solutions. Eligible organizations must be 501(c)(3) public charities and focus on partnerships that strengthen community resilience against discrimination.
Economic Services & Development Racial / Ethnic Justice & Rights

Salary Assistance Grant For Japanese-Language Courses

United States-Japan Foundation
Private
United States
Up to US $30,000
The Salary Assistance Grant for Japanese-Language Courses, administered by the Japan Foundation, Los Angeles, supports U.S. non-profit educational institutions and Japanese heritage language schools facing financial difficulties. Grants cover a portion of the salary and benefits of Japanese language instructors, up to $30,000 per year. Institutions can apply for one or two years of funding, with priority given to new programs and the maintenance of existing programs. Applications must detail cost-sharing plans.
Education - K through 12 Education - Higher Education Cross-Cultural Understanding & Exchanges

Robert & Joyce Stokes Family Scholarship - renewal

Ashland County Community Foundation
Private
United States
Unspecified amount
The Robert & Joyce Stokes Family Scholarship, provided by the Ashland County Community Foundation, supports graduating seniors from Ashland County high schools with a GPA of 2.75 or above and at least two varsity letters. This scholarship honors the Stokes' commitment to education and service. Recipients can renew the scholarship for up to three years by maintaining full-time enrollment and a GPA of 2.75, ensuring ongoing support for their educational journey.
Career / College Preparation Academic Scholarship Programs

Defending Basic Freedoms Grant

Herb Block Foundation
Private
United States
US $5,000 - US $25,000
The Herb Block Foundation's Defending Basic Freedoms Grant aims to uphold the essential freedoms outlined in the Bill of Rights. This initiative focuses on combating discrimination and prejudice while enhancing the lives of the underprivileged. It provides funding for charitable and educational programs that align with these values. Open to 501(c)(3) nonprofit organizations nationwide, the grant encourages accountability among government agencies and supports relevant contemporary societal issues.
Government Accountability & Transparency Civil Rights

Implementation of Synthetic Biology Principles in Immunology

Chan Zuckerberg Initiative Foundation
Private
United States
Up to US $300,000
The Chan Zuckerberg Initiative is calling for innovative research proposals that leverage synthetic biology principles to advance immunology. This funding opportunity supports projects aimed at enhancing immune cell functionality, developing synthetic bio-circuits, and creating artificial immune systems. The initiative seeks transformative research that can lead to significant breakthroughs in understanding and treating immune-related diseases, ultimately impacting public health on a large scale.
Immune System Diseases Synthetic Biology

Cohen Family and L. and V., Inc. Family Scholarship

Community Foundation of Elmira-Corning and the Finger Lakes, Inc.
Private
United States
US $1,300
The Cohen Family and L. and V., Inc. Family Scholarship aims to alleviate financial barriers for students pursuing nursing or related fields. Offered by the Community Foundation of Elmira-Corning and the Finger Lakes, this scholarship is designed for adults, including non-traditional and vocational students. With a focus on broadening access to education, the foundation provides support to those seeking further education, ensuring that help is available throughout the application process.
Nursing Medical Education & Professional Training

Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
This funding opportunity aims to support innovative research projects targeting previously undruggable classes of proteins associated with challenging human diseases. By encouraging early-stage exploratory projects, it seeks to foster the development of novel methods and agents that can selectively modulate these hard-to-target proteins, ultimately advancing therapeutic strategies and improving patient outcomes.
Pharmacology Rare Diseases

CSA Elizabeth Soeder Scholarship

Center for Scholarship Administration (CSA)
Private
United States
Unspecified amount
The CSA Elizabeth Soeder Scholarship provides financial support to deserving students from Cape May County, NJ, facilitating their pursuit of higher education. This scholarship is available for one academic year and is open to high school seniors and current college students who demonstrate financial need and academic ability, maintaining a minimum GPA of 3.0. Recipients can reapply for funding in subsequent years, with awards not guaranteed, ensuring a competitive selection process.
Career / College Preparation Academic Scholarship Programs

CSA Grace D. Dreher Memorial Scholarship

Center for Scholarship Administration (CSA)
Private
United States
Unspecified amount
The CSA Grace D. Dreher Memorial Scholarship supports deserving students from Stroudsburg High School. Funded by the Grace D. Dreher Memorial Trust, it offers one-year scholarships for full-time college enrollment at accredited institutions in the U.S. Eligible applicants must demonstrate financial need and have a minimum GPA of 2.0 on a 4.0 scale. Current recipients may reapply, but awards are not guaranteed and depend on the applicant pool each year.
Career / College Preparation Academic Scholarship Programs

The NIDDK Disorders of Gastrointestinal Interoception Consortium Clinical Centers (DGIC) (360625)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDDK Disorders of Gastrointestinal Interoception Consortium Clinical Centers (DGIC) aims to enhance understanding of gastrointestinal disorders by expanding the previous Gastroparesis Consortium's research scope. This initiative will include adult and pediatric conditions linked to impaired interoceptive processing, utilizing multidisciplinary approaches to uncover mechanisms connecting GI function to symptoms, identify biomarkers for treatment efficacy, and explore new therapeutic targets for future clinical trials.
Digestive System Health & Diseases Medical Technology, Devices, and Equipment

CSA Stanley V. and Mary G. Mahalick Scholarship

Center for Scholarship Administration (CSA)
Private
United States
Unspecified amount
The Stanley V. and Mary G. Mahalick Scholarship is a one-year award for deserving students from Mahanoy Area High School or Marian Catholic High School. Funded by the Center for Scholarship Administration, this scholarship supports students with a minimum GPA of 2.5 who demonstrate financial need and good moral character. Recipients may reapply for additional funding up to four years, provided they maintain full-time enrollment in an accredited college or university.
Career / College Preparation Academic Scholarship Programs

PEN Prison Writing Awards

PEN America
Private
United States
US $75 - US $300
The PEN Prison Writing Awards, initiated after the 1971 Attica Prison Riots, invites incarcerated writers in the U.S. to submit unpublished works across various genres including Poetry, Fiction, and Memoir. Winners receive cash prizes and their works are published in an annual anthology. This program not only recognizes talent within carceral facilities but also supports writers through mentorship, fostering creativity and expression in challenging circumstances.
Writing & Literature Correctional Systems & Prisons

American Association of University Women Scholarship

Community Foundation of Elmira-Corning and the Finger Lakes, Inc.
Private
United States
US $600
The American Association of University Women Scholarship supports women who are resuming their education after interruptions, specifically targeting adult students aiming to complete a 4-year degree. Applications open on November 1 and close on February 1. This scholarship encourages women, particularly sophomores at Corning Community College planning to transfer to a 4-year institution, to pursue their academic goals without financial barriers, thereby enhancing educational opportunities in the community.
Academic Scholarship Programs Student Retention & Drop-Out Prevention

Institutional Project Support (IPS) Grant Program

Japan Foundation, New York
Private
United States
Up to US $150,000
The Institutional Project Support (IPS) Grant Program by the Japan Foundation aims to enhance Japanese studies in the U.S. by providing up to $150,000 annually for three years. Eligible U.S. institutions must match the grant and focus on innovative proposals that stimulate growth in Japanese studies. The program prioritizes projects that create tenured positions and address national needs, while excluding political or commercial activities. Grants cover faculty salaries, travel, and teaching materials.
Asian / Pacific Island Culture & Heritage Cross-Cultural Understanding & Exchanges

Institutional Project Support - Small Grant Program

Japan Foundation, New York
Private
United States
Up to US $25,000
The Japan Foundation's Institutional Project Support - Small Grant Program provides up to $25,000 for U.S.-based 501(c)(3) organizations to enhance Japanese Studies infrastructure. The program targets institutions facing challenges in maintaining their programs, particularly smaller or newer entities without established Japanese Studies initiatives. Eligible projects should focus on promoting Japanese Studies, with funding available for faculty salaries, travel, research materials, and conference expenses. Applications are accepted from institutions committed to advancing their Japanese Studies offerings.
Asian / Pacific Island Culture & Heritage Cross-Cultural Understanding & Exchanges

AED Grants

USA Football
Association/Society
United States
Unspecified amount
The AED Grant, offered by USA Football, supports youth organizations, middle schools, and high school girls flag football programs in acquiring essential Automated External Defibrillators (AEDs). This initiative ensures that lifesaving equipment is readily available during emergencies. Recipients receive specific AED models, comprehensive training, and certification to guarantee proper usage. Eligible applicants must be non-profits in good standing with USA Football, promoting safety and preparedness on the field.
Youth Services Football

Heart of Illinois Community Foundation Scholarships

Heart of Illinois Community Foundation
Association/Society
United States
US $500 - US $10,000
The Heart of Illinois Community Foundation Scholarships provide financial support for high school seniors in Macon, Moultrie, and Piatt County. Annually, over 70 students benefit from these awards, ranging from $500 to $10,000, to pursue higher education. Funded by generous donors, the program aims to enhance educational outcomes in the community. Eligibility includes being a graduating senior or an existing college student previously awarded a multi-year scholarship. Various criteria may apply to each scholarship.
Career / College Preparation Academic Scholarship Programs

USA Football’s Flag Equipment Grant

USA Football
Association/Society
United States
Unspecified amount
USA Football’s Flag Equipment Grant supports youth organizations and schools in need of flag belts and footballs for girls flag football programs. Eligible applicants include legally designated non-profits in good standing with USA Football. The grant provides USA Football-branded equipment, with quantities determined by the application responses. Organizations are unable to select items from a catalog, as awards are issued directly from warehouse partners, ensuring accessibility for participants.
Youth Services Football

Lipscomb Family Foundation Grant

Lipscomb Family Foundation
Private
Calhoun County, South Carolina, Fairfield County, South Carolina +6 more
Unspecified amount
The Lipscomb Family Foundation Grant supports youth development in the South Carolina Midlands, focusing on character building and educational opportunities. Established by Margaret and Guy Lipscomb, the foundation aims to foster inquisitive, productive, and caring individuals under 19 years of age. Grants are typically awarded to 501(c)(3) organizations in specific counties, promoting positive growth within the community and enhancing relationships among families. This initiative is dedicated to shaping the next generation of responsible and healthy adults.
Youth Development & Leadership Youth Services

Brinson Prize Fellowship Program

The Brinson Foundation
Private
United States
US $121,000 - US $128,107
The Brinson Prize Fellowship Program, in partnership with The Brinson Foundation, offers support for early career astrophysicists and cosmologists pursuing innovative research in observational cosmology. This program emphasizes the importance of connecting science with society and provides up to three years of funding, including a stipend for independent research. Applicants must hold a PhD in relevant fields and can apply for fellowships starting in 2026, which include professional development opportunities.
Astronomy & Astrophysics Space Science Physics +1 more

Melvin & Lena Oneto Scholarship

Elk Grove Regional Scholarship Foundation
Association/Society
United States
US $1,500
The Melvin & Lena Oneto Scholarship, funded by the Elk Grove Regional Scholarship Foundation, provides $2,500 for students pursuing education in agriculture. Applicants must maintain a minimum GPA of 3.0 and demonstrate full-time enrollment at a four-year college. Participation in school and community activities is required. This scholarship aims to support students from various Elk Grove High Schools, fostering academic and community engagement.
Career / College Preparation Academic Scholarship Programs

Dr. David Whiston Leadership Award

American Dental Association (ADA) Foundation
Association/Society
United States
US $5,000
The Dr. David Whiston Leadership Award, offered by the ADA Foundation, aims to support emerging leaders in oral health. This award grants $5,000 to individuals demonstrating commitment to enhancing access to dental education and employment opportunities. Eligible applicants include dental students, early-career dentists, and those under 40. Selection criteria focus on leadership potential and contributions to the profession, emphasizing community engagement and public health advancement. Visit ADAF.org for application details.
Dental Health Job Creation

CareQuest Emergent & Relief Fund

Carequest Institute For Oral Health Inc
Private
American Samoa, Guam +4 more
Unspecified amount
The CareQuest Emergent & Relief Fund aims to address the unique challenges faced by historically underserved communities in the healthcare system, particularly in oral health. This fund supports innovative approaches, urgent clinical responses, and immediate relief efforts for community crises. Grants are targeted at organizations demonstrating commitment to equity in health services, ensuring that aid reaches those most in need. With a focus on transformative change, this initiative seeks to enhance access and improve health outcomes across diverse populations.
Disaster Relief / Humanitarian Aid Dental Health Minority Services

Repurposing Research for Chicago - Track 2 – Patient Groups

Cures Within Reach
Private
United States
Up to US $125,000
The "Repurposing Research for Chicago - Track 2" grant supports early-stage investigators conducting clinical repurposing trials for unsolved diseases. Researchers must be within 10 years of completing an advanced degree or residency, and trials can utilize telehealth. Funded institutions must be located in the Chicagoland area, with budgets up to $100,000 available. This initiative aims to enhance the quality of life through efficient medical repurposing, connecting various stakeholders to expedite treatment delivery.
Diseases & Conditions Rare Diseases

Mary & Al Tsukamoto Memorial Scholarship

Elk Grove Regional Scholarship Foundation
Association/Society
United States
US $1,500
The Mary & Al Tsukamoto Memorial Scholarship aims to foster educational opportunities through grants and scholarships, focusing on community needs. It offers two scholarships of $1,500 each, requiring applicants to submit a 500-word essay on the phrase 'Justice for All' and its impact on their family. Eligibility includes a minimum GPA of 3.0 and full-time student status, with special consideration for immigrant families. Participation in community activities is required, while school activity involvement is not.
Career / College Preparation Academic Scholarship Programs

Grants for 501(c)(3) in South Carolina Highlights

Looking for grants for 501(c)(3) in South Carolina?


Read more about each grant below or start your 14-day free trial to see all grants for 501(c)(3) in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grants for 501(c)(3) in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Grants for 501(c)(3) in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Grants for 501(c)(3) in South Carolina over $25K in average grant size

40 Grants for 501(c)(3) in South Carolina over $50K in average grant size

32 Grants for 501(c)(3) in South Carolina supporting general operating expenses

100+ Grants for 501(c)(3) in South Carolina supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Health Care Access & Delivery

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for 501(c)(3) in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Grants for 501(c)(3) in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Grants for 501(c)(3) in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Grants for 501(c)(3) in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Grants for 501(c)(3) in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081