Best Grants for 501(c)(3) in South Carolina

The ACLS Graduate Internships on the Spiritual Infrastructure of the Future program offers summer opportunities for current PhD students in the humanities and social sciences to engage with organizations addressing the evolving American religious landscape. This initiative aims to cultivate future leaders by providing practical experiences that demonstrate the value of doctoral training beyond academia. Supported by the Templeton Religion Trust, the internships encourage collaboration between fellows and community organizations, fostering a deeper understanding of spiritual infrastructures.

The RTK Scholars Program, funded by RTK Environmental Group, provides a $1,500 scholarship to support students pursuing careers in science, particularly in environmental studies, biology, and engineering. This initiative aims to cultivate the next generation of experts in environmental testing and technology. Eligible applicants must maintain a GPA of 3.0 or higher and be enrolled in an accredited institution. The application deadline is May 31 each year, promoting academic excellence and dedication to environmental sciences.

The NIH Independent Scientist Award (K02) supports the development of outstanding scientists by providing three to five years of salary support and protected time for newly independent researchers. This funding opportunity is specifically for applicants proposing research that does not involve leading an independent clinical trial, allowing them to gain experience in trials led by others. Key deadlines for applications span from June 2024 to February 2027.

The Rea Charitable Trust, established in 2009 by Mrs. Isabel McClintic Rea, prioritizes support for charitable organizations that focus on the arts. Administered by Comerica Bank & Trust, the trust provides funding through structured application periods for organizations based on their names. Eligible applicants must be 501(c)(3) organizations, limited to one application per year. The trust aims to uphold Mrs. Rea's legacy by fostering artistic endeavors within the community.

The PLTW Gateway program, supported by Lockheed Martin, offers grants for schools to implement STEM and CTE-aligned curricula. Aimed at enhancing educational access for students, it provides funding of $10,000 for the 2026-2027 academic year. Eligible schools include public and charter institutions across the U.S. This initiative, part of a long-standing partnership since 2007, addresses the critical need for future engineers and scientists, benefiting over 77,000 students through innovative coursework.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Calvin H. & Elizabeth L. Topliff Scholarship

Georgia Mathews, mother to Marion Community Foundation board member, Spencer Mathews, created this endowed scholarship in 2023 in honor of her parents. The scholarship will be awarded to Marion County students who are pursuing a career in either education or engineering, with special consideration for students who will be attending Ohio Northern University, which is where Georgia’s parents met.

Betty Beatty Topliff was born in Pittsburgh but ended up in Marion after meeting Calvin at Ohio Northern and moving to his hometown of Marion. Betty (1928-2022) was a dedicated teacher for 30 years, most recently at Ridgedale High School. Calvin (1924-2009) was an Army veteran who served in Europe during WWII and was awarded the Bronze Star. Calvin retired from the marketing department of Ohio Edison Marion Division after 36 years of service.

Following retirement, Calvin and Betty were Florida snowbirds, but Betty returned to Marion after Calvin’s death to be with her beloved children, grandchildren, and great grandchildren.

The Nature Awards for Inspiring Women in Science, particularly in the Science Outreach category, honors initiatives that empower girls and young women in STEM fields. With a focus on engagement and retention, the awards aim to celebrate projects that encourage participation in natural sciences, technology, engineering, mathematics, and medicine. Winners will receive significant cash prizes and opportunities for mentorship, creating pathways for future generations of women in science.

The PLTW Gateway Program Expansion, in partnership with Lockheed Martin, aims to enhance STEM education in schools across the United States. With a total grant of $10,000 for the 2026-2027 academic year, this initiative focuses on expanding existing PLTW Gateway programs, allowing schools to introduce new units and train additional teachers. Since 2007, Lockheed Martin's support has enabled over 300 programs, providing critical skills to more than 77,000 students nationwide.

The Public Wireless Supply Chain Innovation Fund Grant Program seeks to advance secure computing environments for AI-powered Radio Access Networks (RAN). This initiative aims to foster innovative solutions that can enhance operational revenue, provide cost efficiencies, and develop third-party services, thereby demonstrating viable business cases. By supporting the integration of AI capabilities, the program accelerates commercial deployments and promotes the export of secure, interoperable equipment.

The NIH Common Fund is planning to issue a NOFO to continue the Bridge2AI program, which aims to develop AI-ready datasets and best practices for biomedical research. This next stage will leverage these datasets to address significant health challenges and foster multidisciplinary collaboration. The initiative will support 3-5 Centers focused on trustworthy AI in biomedical research, creating frameworks for reproducibility, transparency, and advancing the AI workforce in health sciences.

The Hanna H. Gray Fellows Program, supported by the Howard Hughes Medical Institute, aims to enhance diversity in the academic research community. It provides funding of $250,000 and a $20,000 annual expense allowance for early-career researchers committed to fostering an inclusive scientific culture. Eligible applicants must hold a PhD or MD, commit to at least 75% research effort, and have no more than 24 months of postdoctoral experience. This initiative empowers fellows to become leaders in science.

TechAccess: AI-Ready America is a nationwide initiative aimed at enhancing AI readiness across the U.S. by fostering collaboration and resource sharing. It targets businesses, organizations, and individuals, ensuring widespread access to AI tools and knowledge. The program includes State Coordination Hubs to connect stakeholders, a National Lead for collaboration, and AI-Ready Catalyst Award Competitions to drive innovative solutions. This comprehensive approach seeks to prepare all sectors for an AI-driven economy, benefiting Americans through practical implementation and workforce development.

The National Science Foundation (NSF) is offering funding through the Engineering (ENG) program, focusing on foundational research in civil, mechanical, and manufacturing innovation. Key areas include advanced manufacturing systems, civil infrastructure, and intelligent dynamic systems. The NSF ENG encourages innovative and transformative proposals that may not require immediate commercial outcomes. Award sizes and durations will vary based on budget availability, aiming to support long-term research advancements.

The Zuckerman Postdoctoral Scholars Program fosters collaboration between leading scientific institutions in the U.S. and Israel by attracting top postdoctoral researchers. With a focus on STEM leadership, this program offers a unique two-year scholarship, allowing scholars to conduct research at participating Israeli universities and North American institutions. The initiative aims to strengthen academic ties, enhance research capabilities, and support the return of talented Israeli scholars to their home institutions, ultimately enriching the global scientific community.

The Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Training Grant supports institutions in developing clinical and translational science training programs. This program aims to enhance the research training of postdoctoral individuals holding doctoral degrees, ensuring a diverse pool of scientists equipped to tackle critical health challenges. Applications must be submitted by 5:00 PM local time of the applicant organization, and non-U.S. entities are not eligible.

The NIH Independent Scientist Award (K02) aims to support the development of independent scientists and enhance their research capabilities. This award offers salary support and protected time for three to five years, specifically for those leading independent clinical trials or feasibility studies. Applicants must demonstrate a need for focused research to advance their careers. Key deadlines for applications span from June 2024 to February 2027, catering to various submission types including standard and AIDS-related grants.

The Ruth L. Kirschstein National Research Service Award (NRSA) offers predoctoral training grants aimed at enhancing clinical and translational science. Administered by the NCATS, this program supports institutions in training aspiring researchers for a PhD or equivalent, ensuring a diverse cohort of scientists equipped to tackle pressing health challenges. The ultimate goal is to cultivate a skilled workforce capable of advancing biomedical research and addressing community health needs effectively.

The NIH R25 program promotes broad participation in the biomedical and behavioral sciences by supporting educational activities. It aims to encourage individuals from diverse and underrepresented backgrounds to engage in research through mentoring networks and research education experiences. This initiative seeks to enhance the workforce by providing opportunities for further study and career advancement in research fields, ultimately contributing to a more inclusive scientific community.

The NSF Core Research in Biological Sciences (BIO Core) program supports innovative research that enhances our understanding of biological systems, from molecular to biome scales. This funding opportunity encourages interdisciplinary proposals and can fund both single and multi-investigator projects. The awards will vary in scope and duration, accommodating exploratory projects and long-term commitments, depending on available funding and alignment with the program's objectives.

The Foundations of Trusted Systems initiative seeks innovative research to develop secure, resilient, and affordable technologies for Command, Control, Communications, Computers, and Intelligence (C4I) and Cyber systems. This Broad Agency Announcement (BAA) aims to establish trusted foundations for hardware and software, building on previous work to enhance information processing systems. Researchers are encouraged to submit white papers for evaluation and potential funding.

The NIH Support for Conferences and Scientific Meetings (R13) provides funding for high-quality conferences that align with public health and scientific missions. Key deadlines for applications include April 12, August 12, and December 12 for the years 2024 through 2026, with specific deadlines for AIDS-related grants as well. This funding opportunity aims to foster collaboration and dissemination of important research findings in relevant fields.

The Hanna H. Gray Fellows Program, funded by the Howard Hughes Medical Institute, aims to enhance diversity in the scientific community by supporting early-career researchers. The program provides funding for postdoctoral training and early faculty years, promoting an inclusive academic culture. Fellows receive an initial salary of $80,000 and a $20,000 annual expense allowance. This initiative helps develop future leaders in biological and biomedical sciences, ensuring equitable opportunities for all backgrounds.

The AHRQ Mentored Clinical Scientist Research Career Development Award (K08) aims to foster a diverse pool of skilled health services researchers. This funding opportunity supports career development for individuals pursuing research that aligns with AHRQ's mission and priorities. Eligible applicants will receive mentorship to enhance their research skills and contributions to the field. Overall, this initiative is crucial for addressing pressing healthcare research needs.

Lexington Medical Center Foundation Inc

Since 1971, Lexington Health has grown and expanded to meet the needs of our community. The Lexington Health Foundation Remains Committed to Quality Care. Foundation-funded programs aim to enhance patient experiences and touch the various areas of care at Lexington Health — Patient, Employee, and Community Care.

Event and Project Sponsorship

Lexington Medical Center supports local organizations and nonprofits throughout the Midlands.

We support local events and causes that enhance the health and vibrance of our community. You can request sponsorship or other assistance for a project or event based in the South Carolina Midlands community.

The American Association of Law Libraries (AALL) Research Fund Grant supports projects that enhance legal information services and law librarianship. With a funding cap of $5,000 per round, the grant encourages diverse scholarship in legal research. Eligibility includes individuals with relevant research experience, while preference is given to AALL members. Applications are reviewed biannually by a jury, ensuring that the most impactful projects receive support. This initiative aims to foster innovation and collaboration within the legal information community.

The Early Stage Innovations (ESI26) program by NASA invites U.S. institutions of higher education to propose innovative, early-stage space technology research. Focused on technologies with low Technology Readiness Levels, the program emphasizes civil-space applications. Proposals should address specific topics, including advancements in hypersonic flows, autonomous technologies for lunar and Martian environments, and new materials for aerospace applications. Collaboration is encouraged among eligible institutions, with support from NASA's Space Technology Research Grants Program.

The Japanese-Language Education Project Grant supports initiatives that enhance Japanese language education across various regions. Offered by the Japan Foundation, Los Angeles, this grant targets workshops, seminars, and original projects that connect language learning with Japan Studies. Eligible applicants include non-profit educational organizations in the U.S. Projects should benefit multiple programs, ensuring a broad impact on Japanese language education. The deadline for applications is two months before the project start date, which must be between April 1, 2025, and March 31, 2026.