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Best Large Grants for Nonprofit Organizations in South Carolina

Find the perfect Large Grants for Nonprofit Organizations in South Carolina on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in South Carolina in the United States.

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$2.62B

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$5K

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9,000+ grants
$2.62B total
$5K median

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EDA FY25 Disaster Supplemental

US Department of Commerce: Economic Development Administration (EDA)
Federal Government
United States
Up to US $50,000,000
The EDA FY25 Disaster Supplemental program provides critical funding to support communities recovering from severe economic distress caused by natural disasters in 2023 and 2024. With no submission deadlines for Readiness and Implementation Paths, and a specific deadline for Industry Transformation applications, this initiative aims to enhance community resilience and improve economic trajectories through strategic projects that engage local stakeholders and private industries.
Economic Services & Development Disaster Preparedness Disaster Relief / Humanitarian Aid +1 more

RFP: Strengthening Leadership Capacity of Local Arts Agencies

Americans for the Arts Inc.
Private
United States
Unspecified amount

About Americans for the Arts

Building Collective Power for the Arts

Americans for the Arts is the nation's leading arts advocacy organization. We mobilize advocates, produce trusted research, and secure bipartisan wins that protect funding and expand arts access nationwide — work we've been doing for more than 65 years.

Americans for the Arts advances the people, organizations, and systems supporting arts and culture across America through advocacy, research, and national convening.

We envision a nation where freedom of creative expression is upheld as a fundamental human right, where arts and culture are woven into the fabric of civic life, resourced in every community, and accessible to everyone.

Request for Proposals (RFP)

Strengthening Leadership Capacity of Local Arts Agencies

Given the essential role of LAAs, and to meet this important moment, AFTA seeks an energized and experienced consulting team with expertise to help it develop a comprehensive strategy to strengthen leadership and field capacity across the LAA ecosystem. This work is not intended to operate in isolation, but rather to complement and build upon existing efforts already underway in the field. The focus is on identifying where AFTA can add value through targeted, strategic support that enhances and aligns with broader sector-wide initiatives. 

This effort will focus on empowering LAA agency leaders—a critical component of AFTA’s strategic direction—to expand their capacity, foster innovation, and advance equity in a rapidly evolving environment. Building on existing efforts across the field, AFTA will invest in strong, effective LAA leadership, broaden cultural access and participation nationwide, and position the field for a more vibrant, resilient, and sustainable future. 

With approximately 2,200 LAAs nationally validated in AFTA’s LAA Wayfinder, the selected consulting team will help AFTA gain a deeper understanding of the gaps, needs and opportunities shaping LAA leadership capacity, with attention to Native, rural, small, midsize, and large communities, and identify where AFTA is uniquely positioned to contribute. These insights will guide AFTA’s future direction in its service to LAAs nationwide and ensure AFTA’s contributions complement—rather than duplicate—the work of other entities, collectively strengthening the broader LAA ecosystem.  

In addition, by intentionally working in partnership with peer organizations and stakeholders across the field—and by understanding gaps in coverage and opportunities for growth—AFTA will be positioned to work with partners to support the expansion of the LAA network in communities where local public cultural infrastructure is limited or absent. This collaborative approach will help ensure more equitable access to arts and culture while reinforcing the role of LAAs as essential community anchors, particularly in underserved regions. 

Art & Culture American Art Nonprofit Growth & Development +1 more

Japanese American Community Foundation Grants

JA Community Foundation
Private
United States
US $2,500 - US $50,000
The Japanese American Community Foundation Grants support programs for the Japanese American and broader Asian American communities. Funding ranges from $2,500 to $50,000 for projects focusing on senior health, history, arts, culture, and youth. Eligible applicants must be registered 501c3 public benefit nonprofit organizations. Note that organizations with open grants cannot apply until their current grant is closed. Submit a Letter of Inquiry (LOI) before the full proposal.
Senior Services History Arts / Culture Access & Participation +1 more

Deb & John Quirk Memorial Scholarship

Hastings Community Foundation Inc
Private
United States
Up to US $40,000

Deb & John Quirk Memorial Scholarship

The Hastings Community Foundation is excited to announce the creation of the Deb and John Quirk Memorial Scholarship. The scholarship will provide a $10,000 annual scholarship and is renewable for a total award of up to $40,000. One scholarship will be awarded each year. This scholarship is only available to graduating seniors from Hastings High, Adams Central, or Hastings Catholic Schools. Applicants must be focused on impacting social justice through their education and future employment, as illustrated through an essay submitted to the scholarship committee.

Education - Higher Education Career / College Preparation Social Justice / Human Rights

Thomas William Bennett Memorial Scholarship Fund

Community Foundation for Palm Beach and Martin Counties
Private
United States
Unspecified amount

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

Thomas William Bennett Memorial Scholarship Fund

He believed that a person could do anything if they sat down and read how to do it. When WWII started, he was the first man from the state of South Carolina to enlist in the U.S. Army. He quickly rose to captain and spent most of the war in the Pacific (the Queen of Fiji considered him a friend). Later, Thomas had a long career at Harcourt Brace publishing.

Education Education - Higher Education Career / College Preparation

Learning Engineering Tools Competition

Tools Competition
Association/Society
Countries
Unspecified amount
The Learning Engineering Tools Competition is a significant funding opportunity aimed at fostering educational technology innovations. It seeks to leverage digital tools, big data, and learning science to improve learner outcomes globally. This competition encourages diverse participants, from students to established companies, to develop solutions that can generate valuable learning data. By promoting collaboration among educators, researchers, and tech innovators, the initiative aims to advance the field of learning engineering and enhance educational practices.
Computer Science & Engineering Educational Access & Equity Literacy

Eula Mae & John Baugh Foundation Grant

Eula Mae And John Baugh Foundation
Private
United States
Unspecified amount

The Baugh Foundation supports progressive, inclusive, nonprofit organizations that reflect the love of Christ by providing assistance to those in need, enriching the lives of children and youth, keeping faith communities informed and engaged, and guarding the wall of separation between church and state.We welcome applications from progressive, faith-based organizations. At this time, the vast majority of our funding goes to progressive Baptist organizations or initiatives, and organizations that work to guard the separation of church and state. We believe that a free church in a free state is dependent upon a functioning democracy.Funding Priorities: 

  • Social justice and advocacy
  • Progressive faith-based journalism
  • Meeting basic human needs
  • Progressive faith-based post-secondary education
  • Inclusivity initiatives
  • Arts and enrichment
Social Justice / Human Rights Basic Human Needs Journalism

Ken and Clara Kolberg Family Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Ken and Clara Kolberg Family Scholarship

This scholarship has been made possible by the generosity of Ken Kolberg and family, who established the Ken and Clara Kolberg Family Scholarship of the Community Foundation for Muskegon County. Teaching is the family business of the Kolberg Family. Ken started teaching in Muskegon Public Schools after WWII and did so for thirty-seven years. Ken and Clara raised five children, of whom four became teachers - two working in Muskegon. Through the establishment of this Fund, the family is assured of having an impact on students far into the future. This Fund will support Muskegon students pursuing careers in education, especially minority students so greatly needed as teachers in our school systems.

Education Education - Higher Education Career / College Preparation

Academy Sports + Outdoors Donations

Academy Sports + Outdoors
Corporate
Aiken County, South Carolina, Alamance County, North Carolina +211 more
Unspecified amount
Academy Sports + Outdoors, a leading sporting goods retailer, supports community initiatives by providing donations to registered 501(c)(3) organizations. Their focus is on promoting safety and responsibility in sports and outdoor activities. Proposals must foster community engagement and must not be affiliated with religious or political groups. Events should take place in areas with Academy stores, ensuring a positive local impact while encouraging active lifestyles and connection among community members.
Recreation Outdoor Recreation Sports & Athletics +1 more

June M. and John C. Vandervelde Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

June M. and John C. Vandervelde Scholarship

This scholarship has been made possible by the generosity of June M. and John C. Vandervelde, who established the June M. and John C. Vandervelde Scholarship of the Community Foundation for Muskegon County. The Vandervelde's are both long-time Muskegon residents. Many Muskegonites will recognize the name "Vandervelde Furniture" which was located on Broadway in Muskegon Heights for many years. Generations of people bought their furniture from Vandervelde's. June is a long active volunteer for many community organizations, and both have a strong belief in and recognize the importance of a college education. This scholarship fund will assist Muskegon County students as they pursue that education.

Education Education - Higher Education Career / College Preparation

Celia C. Newcomb Memorial Scholarship

Crown Point Community Foundation
Private
United States
Unspecified amount
The Celia C. Newcomb Memorial Scholarship, managed by the Crown Point Community Foundation, aims to enrich the lives of South Lake County residents. This scholarship supports Lake County, IN residents pursuing degrees in Education, including high school graduates and adult learners. Applicants must provide an additional essay and meet specific eligibility criteria. It embodies the foundation's mission to address community needs through charitable giving.
Education - Higher Education Adult Education Academic Scholarship Programs +1 more

National PTA Outstanding Advocacy Awards

National Congress of Parents & Teachers
Corporate
United States
Unspecified amount
The National PTA Outstanding Advocacy Awards recognize exemplary efforts by state, local, and individual PTA advocates dedicated to improving the education, health, and well-being of children. Established by the National PTA, these awards highlight four categories of advocacy: Outstanding State PTA Advocacy, Outstanding Local PTA Advocacy, Shirley Igo Advocate of the Year, and Outstanding Youth Advocate of the Year. Awardees will be celebrated at the National PTA’s Legislative Conference in March 2026.
Civic Affairs Education System Policy & Reform Parental Involvement in Education

Lee Shipman Engineering Scholarship

Community Foundation for Mason County, MI
Association/Society
United States
Unspecified amount

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Lee Shipman Engineering Scholarship

This scholarship has been made possible by the generosity of Lee Shipman who established the Lee Shipman Engineering Scholarship Fund of the Community Foundation for Mason County.

Lee Shipman has always had a love for all things electrical as far back as grade school when he added an additional phone in his family home so calls could be answered from more than one location! This eventually led him to get his degree in electrical engineering and a career at Dow Chemical in Ludington. He continued following his passion after retiring from Dow by working with a local Ludington business helping with the selection and modifications of equipment. Through this work, he recognized the real challenges that downtown merchants face. Lee is thankful for the people who have made a difference in his life, from his Latin teacher to coworkers to close friends and, because of this, he wants to give back to others. He established this Scholarship Fund for students pursuing electrical engineering.

Career / College Preparation Academic Scholarship Programs Electrical Engineering

Owen Family Foundation Grant

Louis and Peaches Owen Family Foundation
Private
United States
Unspecified amount
The Owen Family Foundation Grant supports charitable organizations primarily in East Texas and the Minneapolis/St. Paul area, focusing on health, education, human services, and religious initiatives. Organizations must have a 501(c)(3) status and past funding is required for Twin Cities applicants. The foundation is committed to promoting philanthropy and ensuring access to funding for eligible charities, while maintaining a non-discriminatory policy.
Health & Medicine Education Human & Social Services +2 more

Glenn D. Peters Law School Scholarship

Legacy Foundation: Lake County's Community Foundation
Private
United States
Unspecified amount

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 400 funds and approximately $124 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Glenn D. Peters Law School Scholarship

Award 

The Glenn D. Peters Law School Scholarship is awarded to students who will be enrolled in law school for the upcoming Fall semester.

Scholarships are available for tuition costs at an accredited law school located anywhere in the United States of America. While financial need can be a factor, greater weight is assigned to academic achievement and involvement in quality extracurricular activities.

Law Education - Higher Education Educational Access & Equity

ASHRAE President’s Scholarship

American Society Of Heating Refrigerating & A C Engineers
Private
American Samoa, Guam +4 more
Up to US $12,500
The ASHRAE Presidents Scholarship supports full-time students pursuing a Bachelor of Science in engineering, focusing on HVAC and refrigeration. To qualify, applicants must have a minimum GPA of 3.0 and complete at least 45 credit hours with two years remaining before graduation. Scholarships are awarded for the upcoming academic year, beginning in the fall semester, and re-applications are welcomed from previous applicants who meet current criteria.
Engineering Education - Higher Education Career / College Preparation

Leroy McKinney Jr. Memorial Scholarship Fund

Battle Creek Community Foundation
Private
United States
Unspecified amount

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Leroy McKinney Jr. Memorial Scholarship Fund

This scholarship was created in memory of Leroy McKinney Jr., who was a graduate of Battle Creek Central High School, Class of 1988. Upon graduation, he studied Pre-Engineering in college. He also had an entrepreneurial spirit. Though he struggled with mental illness, one of his proudest accomplishments in life, was returning to college as an adult and completing his Bachelor's degree in Business Management. He would be honored to know this scholarship was created in his legacy to support other African American men to pursue their education in these fields.

Engineering Education - Higher Education Black American Services

AccessLex: Diversity Pathway Intervention Grant Program

AccessLex Institute
Private
United States
US $200,000 - US $300,000
The AccessLex Diversity Pathway Intervention Grant Program aims to support initiatives that facilitate the entry of college students from historically underrepresented groups into law school. By providing funding of $200,000 to $300,000 over 12 to 24 months, the program seeks to improve enrollment and success rates for these students. AccessLex Institute emphasizes research-backed strategies and collaborative programs to enhance educational outcomes in legal education.
Law Educational Access & Equity Education - Higher Education

Culture Works Leonard P. Roberts Memorial Scholarship

The Dayton Foundation
Private
United States
US $1,000
The Culture Works Leonard P. Roberts Memorial Scholarship honors Mr. Roberts' dedication to business and the arts. This scholarship is available for graduating high school seniors and current college students in the Dayton Region who actively participate in the arts. Eligible applicants must reside in specific counties and maintain a minimum GPA of 2.0. Preference is given to students majoring in the arts, business, or engineering, but all fields of study are welcome to apply.
Engineering Academic Scholarship Programs Art Education +1 more

Chick-fil-A Community Scholars

Chick-fil-A
Private
Canada, Puerto Rico +1 more
Up to US $25,000
The Chick-fil-A Community Scholars program awards up to thirteen $25,000 scholarships annually to students demonstrating academic excellence, community service, and financial need. In addition to financial support, recipients participate in a year-long mentoring and leadership development program. This initiative aims to cultivate future leaders who are committed to serving their communities, while also alleviating educational costs associated with attending accredited colleges or vocational schools.
Community Services Youth Development & Leadership Academic Scholarship Programs

Paul and Helen Lenchuk Engineering Student Scholarship Program

CONCRETE MASONRY AND HARDSCAPES ASSOCIATION
Private
Canada, United States
US $5,000
The Paul and Helen Lenchuk Engineering Student Scholarship Program, established by the NCMA Education and Research Foundation, aims to support full-time graduate students in engineering fields across the U.S. and Canada. With a focus on innovative uses of concrete masonry, this program awards a non-renewable $5,000 scholarship annually. Eligible candidates must maintain a minimum 3.0 GPA and demonstrate proficiency in English, ensuring a commitment to advancing the concrete masonry and hardscape industry.
Architecture Engineering Civil Engineering +1 more

Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed) (355586)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The MOSAIC Postdoctoral Career Transition Award (K99/R00) aims to enhance diversity in the biomedical sciences by supporting early career investigators from diverse backgrounds. This program facilitates the transition from mentored postdoctoral positions to independent faculty roles. Awardees will receive NIH research support and engage in professional development, mentoring, and networking activities to foster their competitive research careers, ultimately contributing to a more diverse scientific workforce in NIH mission areas.
Diversity, Equity & Inclusion Science Health & Medicine +2 more

Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) Infrastructure – Clinical Research Sites (U24 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health (NIH) is continuing its support for the NeuroNEXT initiative, which focuses on conducting clinical trials and biomarker validation studies for neurological disorders. This infrastructure aims to foster innovation and enhance the development of effective neurotherapeutics for both adult and pediatric populations. While applications for network clinical research sites are not currently being solicited, this notice allows potential applicants to prepare collaborative and responsive applications.
Neurological Diseases & Disorders Health Care Access & Delivery Emerging Technology Development

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) (357658)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The Limited Competition Small Grant Program under the NCATS CTSA aims to enhance the research capabilities of scholars transitioning to independent academic translational scientists. This program supports diverse clinical and translational science projects, including pilot studies and methodology development. The R03 grants are designed for short-term projects with limited resources that generate preliminary data for future R01 applications, thereby fostering innovation and advancing health research.
Science Biology Health & Medicine +2 more

Jessica Lynn Herman Memorial Scholarship

Orange County Community Foundation
Private
United States
Unspecified amount

Scholarship funds are established by local individuals, families, businesses and organizations. They provide tuition assistance and financial support to new and continuing college students, and many offer renewable awards.

Jessica Lynn Herman Memorial Scholarship

Graduating high school senior from the Huntington Beach High School District with a passion for both the sciences and humanities and demonstrated commitment to mentoring or tutoring. 

Humanities & Social Science Education - Higher Education Career / College Preparation

Curtis Rex Carter Applied Science Scholarship

Community Foundation of the Ozarks Inc.
Private
United States
US $2,500
The Curtis Rex Carter Applied Science Scholarship provides a $2,500 award to graduating high school seniors from select schools who are majoring in Electrical, Chemical, Computer Engineering, Chemistry, or Applied Micro-biology. This renewable scholarship supports students maintaining a 2.8 GPA and enrolled in at least 12 credit hours. Applicants must demonstrate financial need by submitting FAFSA-SAI and an essay. The scholarship aims to foster academic excellence and support students in pursuing their educational goals.
Engineering Academic Scholarship Programs Career / College Preparation

We Serve to Remember 9/11 Day of Service Grants

Youth Service America
Corporate
American Samoa, Guam +4 more
US $1,000

Youth Service America

Youth Service America believes that youth, communities, and our democracy thrive when we all work together for the common good. YSA is a leading global nonprofit that activates young people, ages 5-25, to find their voice, take action, and acquire powerful civic and 21st Century skills as they solve problems facing their communities. YSA supports its activation campaigns with grants, training and resources, and recognition programs for young people and their adult champions. Youth-led projects use Awareness, Service, Advocacy, and Philanthropy (ASAP) strategies to create social and environmental change.

Our vision is that youth participation in working together for the common good becomes the common expectation and common experience of all young people in America. Even though youth participation rates are at or near record-high levels, we’re still leaving 3 of every 4 young people out, and participation rates are even lower among youth from underserved low-income communities and communities of color.

We Serve to Remember 9/11 Day of Service Grants

YSA’s We Serve to Remember 9/11 Day of Service Grants are for organizations, schools, and youth changemakers ages 5-25 to lead service projects on or around September 11, 2026. Programming efforts should also honor and pay tribute to those who lost their lives on September 11, 2001, their families, and those who rose in service in response to that tragedy.

This year, YSA will award up to 100 grants of $1,000 each. Grantees are required to engage at least 100 youth as volunteers in planning and implementing the service activities.

Reflecting on the spirit of togetherness that brought people together in the days, weeks, and months after September 11th, we are especially looking for ideas that bring together all members of the community.

Community Services Youth Services Youth Development & Leadership

Large Grants for Nonprofit Organizations in South Carolina Highlights

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Grant Insights : Large Grants for Nonprofit Organizations in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Large Grants for Nonprofit Organizations in South Carolina over $25K in average grant size

40 Large Grants for Nonprofit Organizations in South Carolina over $50K in average grant size

32 Large Grants for Nonprofit Organizations in South Carolina supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in South Carolina supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081