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Find the perfect Large Grants for Nonprofit Organizations in South Carolina on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in South Carolina in the United States.
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$2.62B
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$5K
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Grand Traverse Regional Community Foundation
The Grand Traverse Regional Community Foundation began in 1992 when a group of community champions came together around a vision to give back to our region then, now, and forever.
This vision lives on within our organization today as we support the people and places of Antrim, Benzie, Grand Traverse, Kalkaska, and Leelanau Counties and the Grand Traverse Band of Ottawa & Chippewa Indians.
Together with our partners, we spark positive change for a variety of local causes, including youth, arts and culture, education, environment, and health and human services, across our region.
Regional Scholarships
We believe that post-secondary education is key to healthy, resilient, and thriving communities and are pleased to partner with generous community donors to create and offer a variety of scholarship opportunities for local students across the region.
Robert S. “Robbie” Detwiler Memorial Scholarship Endowment (Regional)
Available for graduating high school seniors and enrolled college students from Antrim, Benzie, Grand Traverse, Kalkaska, or Leelanau County that are pursuing a degree in architecture or the building trades.
Marion Community Foundation
Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.
Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.
Cornell Goodman Scholarship
Adam and Gina Goodman created this scholarship fund in 2011 to honor the memory of Adam’s grandfathers Maurice V. Cornell and Bertram Goodman, longtime residents of the Marion area.
Maurice (1912-2001) was a graduate of Mt. Vernon High School and The Ohio State University. He held membership in Lombda Chi Alpha fraternity, Elks Lodge #32, 32nd degree Mason, Rotary, First Presbyterian Church, the Marion Country Club, and Symposiarchs. He served in the US Navy during World War II in the South Pacific. He was vice president of Marion Power Shovel for eight years and retired as the regional manager of Bucyrus-Erie Co. after 10 years.
Bertram (1921-2003) was an orthodontist in Marion from 1946-1980. He was a US Navy veteran who served in the Korean Conflict. He was a member of the Marion Lions Club and Temple Israel.
The scholarship supports students who have attended a high school in Marion County. The fund gives special consideration to students pursuing a college degree in a business-oriented field, such as accounting, economics, finance, or marketing. Recipients must rank in the upper 25th percentile of their high school graduating class, or, if in college, maintain a GPA of 3.0 or better.
Project Lead the Way inc.
School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world.
PLTW Gateway
PLTW Gateway (6-8) opens paths that create meaningful futures. It connects students to careers in areas they can, and can't, imagine. Through explorations of skilled trades, coding and robotics, flight and space, human body systems, and more, PLTW Gateway fuels students’ passion for discovery. As they engage in hands-on, collaborative problem solving focused on real-world challenges, students use and stretch their imaginations in brand-new ways that connect their learning to life. All the while, students step into roles spanning the career landscape—a crucial experience during this transitional time in their lives, long before they enter their degreed or skilled trade professions.
PLTW Gateway - Program Expansion (3M)
3M forms lasting partnerships with communities and provides resources to help them succeed and grow – ensuring a more interconnected and thriving world. 3M inspires the next generation of science leaders through the following goals:
3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM.
The Council of Independent Colleges
Founded in 1956, the Council of Independent Colleges (CIC) is an association of nonprofit independent colleges and universities, state-based councils, and higher education affiliates that works to support college and university leadership, advance institutional excellence, and enhance public understanding of independent higher education’s contributions to society.
CIC is the major national organization that focuses on providing services to leaders of independent colleges and universities and state-based councils. CIC offers conferences, seminars, publications, and other programs and services that help institutions improve educational quality, administrative and financial performance, student outcomes, and institutional visibility.
NetVUE Grant Programs
NetVUE offers a variety of grants to member institutions, supporting programming for students and professional development for faculty members and staff. Grants support projects ranging from one to four years in length. Grant programs are tailored to differing circumstances among member institutions, including their particular areas of interest, their bandwidth and capacity for administering projects, and the depth of their previous engagement with vocational exploration and discernment. NetVUE grants are administered by the Council of Independent Colleges, with generous support from Lilly Endowment Inc.
NetVUE Professional Development Awards
Colleges and universities that are members of NetVUE are committed to campus activities that encourage vocational exploration by students. Many NetVUE campus leaders have observed, however, that supplemental funding at even modest levels to support opportunities for the professional development of staff and faculty members would enable their institutions to strengthen vocational exploration programming. In an era of careful institutional budgeting, institutional operating funds are not always available for such professional development opportunities. NetVUE Professional Development Awards seek to address this need.
NetVUE Professional Development Awards may be requested for use over one year for professional development activities that enhance the knowledge, skills, and expertise of faculty and staff members who play important roles in undergraduate vocational initiatives. The purpose of this grant is to develop campus conversations about vocation and to deepen the capacity of those who lead vocational exploration efforts at NetVUE member institutions. A special initiative within this grant, focusing on diversity, equity, and inclusion, allows for proposals of up to $25,000.
Funds may be used for a range of purposes, but not to substitute for faculty and staff costs that the institution is presently providing for its vocational exploration activities. Grant funds could, for example, support reading groups, faculty/staff retreats, or bringing speakers to campus; funds may be used to provide materials, pay expenses for travel and/or meals, and offer modest stipends.
Founded in 2016, this program supports nonfiction filmmakers or filmmaking teams working on their first or second feature-length documentary.
In this year-long program, 9 filmmakers will receive:
You do not need a fiscal sponsor to apply for the (Egg)celerator Lab. However, if you are selected for the Lab, you must secure a US fiscal sponsor, or be a 501(c)(3), to receive the funds. If granted, we can help advise on finding a fiscal sponsor.
American Gastroenterological Association
The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, AGA represents members from around the globe who are involved in all aspects of the science, practice, and advancement of gastroenterology. The AGA Institute administers the practice, research, and educational programs of the organization.
AGA-Takeda Pharmaceuticals Research Scholar Award in Inflammatory Bowel Disease
This award provides funding for three years to early-career faculty (i.e., investigator, instructor, research associate or equivalent) working toward an independent career in inflammatory bowel disease (IBD) research.
Objective
The objective of the AGA Research Foundation Research Scholar Award (RSA) is to support early-career investigators working toward independent and productive research careers in digestive diseases by ensuring that a major proportion of their time is protected for mentored research (i.e., a minimum of 50 percent effort dedicated to the proposed project). This award will support junior faculty (not fellows) who have demonstrated exceptional promise and have some record of accomplishment in research pertaining to inflammatory bowel disease.
Review all of the benefits AGA Research Scholar Award recipients are entitled to on the award policies page.
Application Requirements
Award Overlap
Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Acute Myeloid Leukemia (AML) Fund
Help with healthcare costs for acute myeloid leukemia
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
Approved medications
Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.
Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant.
Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Chronic Lymphocytic Leukemia (CLL) Fund
Help with healthcare costs for chronic lymphocytic leukemia
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
Approved medications
Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See Approved medication list for this condition.
Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant.
Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Hemophilia Fund
Help with healthcare costs for hemophilia
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
Approved medications
Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.
Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant.
Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Hemophilia Health Equity Fund
Help with healthcare costs for hemophilia (health equity fund)
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code.
Approved medications
Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.
Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant.
Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Mucopolysaccharidosis Type III (MPS III) Fund
Help with healthcare costs for mucopolysaccharidosis type III
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
Approved medications
Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.
Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant.
Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Mucopolysaccharidosis Type VII (MPS VII) Fund
Help with healthcare costs for mucopolysaccharidosis type VII
This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
Approved medications
Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.
Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant.
Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Mucopolysaccharidosis Type VII (MPS VII) Health Equity Fund
Help with healthcare costs for mucopolysaccharidosis type VII (health equity)
This TotalAssist Health Equity Fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code.
Approved medications
Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.
Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant.
Mission: To continually improve the Marion Area community through philanthropy, leadership and civic engagement. McBride Family Scholarship
Created in memory of the late Doris Elaine McBride (1928-2022), the McBride Family Scholarship Fund was created by Russ & Marilyn McBride in 2023. Applicant should have attended any Marion County high school and will major in education, medicine, or health care.
Mission: To continually improve the Marion Area community through philanthropy, leadership and civic engagement. Max Ross Memorial ScholarshipThe Max Ross Memorial Scholarship Fund was created in 2018, shortly after his passing, by his family to support Marion students pursuing degrees in the field of education. Max was well known in Marion, having served as Marion County Sheriff, educator, businessman, and coach.
Mission: To continually improve the Marion Area community through philanthropy, leadership and civic engagement. Marion Music Club ScholarshipMarion Music Club , which has existed for more than 100 years (formerly known as the Marion Lecture and Recital Club), is open to anyone who loves music and supports the performing arts in Marion. Members range in age from 20-80 and includes those active with the Marion Area Orchestra, Marion Concert Band, area music stores, and private teachers, as well as students. They offer monthly programs for the community, including musical arts, poetry, theater, dance, instrumentals, and history — both live and via their YouTube channel. The Club encourages the arts in Marion by supporting the Palace Cultural Arts Association and Marion Civic Chorus.
Looking for large grants for nonprofit organizations in South Carolina?
Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in South Carolina recommended for your specific programs.
How common are grants in this category?
Common — grants in this category appear regularly across funding sources.
Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in South Carolina?
Most grants are due in the first quarter.
What's the typical grant amount funded for Large Grants for Nonprofit Organizations in South Carolina?
Grants are most commonly $15,000.
What's the typical amount funded for South Carolina?
Grants are most commonly $74,506.
What's the total number of grants in Large Grants for Nonprofit Organizations in South Carolina year over year?
In 2024, funders in South Carolina awarded a total of 24,410 grants.
Among all the Large Grants for Nonprofit Organizations in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.
1. Education
2. Philanthropy, Voluntarism & Grantmaking Foundations
3. Human Services
How is funding for Large Grants for Nonprofit Organizations in South Carolina changing over time?
Funding has increased by 22.06%.
How does grant funding vary by county?
Greenville County, Richland County, and Charleston County receive the most funding.
| County | Total Grant Funding in 2024 |
|---|---|
| Greenville County | $580,646,902 |
| Richland County | $413,417,941 |
| Charleston County | $355,724,083 |
| Spartanburg County | $325,246,878 |
| Pickens County | $159,596,081 |