Best Large Grants for Nonprofit Organizations in South Carolina

The DoW Neurofibromatosis Investigator-Initiated Research Award addresses critical needs in neurofibromatosis research, aiming to enhance patient care through innovative projects. It supports various research phases, excluding clinical trials, and encourages collaboration between scientists and clinicians. The funding mechanism includes two levels based on participation in optional features, such as the Open Science Initiative and collaboration with qualified partners, promoting data sharing and collaborative research efforts.

The FY26 Neurofibromatosis Research Academy – Scholar Award supports early-career independent investigators focusing on neurofibromatosis research. Scholars are required to be within 10 years of their terminal degree and must designate a Career Guide for mentorship, fostering collaboration. This initiative aims to advance impactful research and develop skilled researchers in a supportive environment, addressing critical areas of emphasis in neurofibromatosis research.

The FY26 Neurofibromatosis Research Program's Exploration-Hypothesis Development Award encourages innovative, high-risk research concepts in neurofibromatosis (NF). This award aims to support groundbreaking studies that will pave the way for future scientific inquiries. Proposals should present a well-defined, testable hypothesis grounded in sound scientific rationale. While preliminary data is encouraged, it is not a prerequisite for submission, allowing researchers to explore novel paradigms and perspectives in NF research.

The USF Community Impact Grant, established by USA Swimming and the USA Swimming Foundation, aims to enhance competitive opportunities in swimming clubs. Grants of up to $5,000 are available for registered USA Swimming clubs committed to fostering community engagement and collaboration. Eligible clubs can renew their grant for up to three years, promoting diverse access to swimming programs. This initiative particularly supports clubs that partner with educational or public entities and those led by women or minorities.

The Community Foundation of NCW is a tax-exempt philanthropic organization that helps individuals, families, businesses, and agencies support charitable causes throughout Chelan, Douglas, and Okanogan counties.

Dr Don Fager Nursing Scholarship

This scholarship is awarded to current or previous Wenatchee Valley College nursing students seeking further education in a nursing program at an accredited school in the United States of America.

The Community Foundation of NCW is a tax-exempt philanthropic organization that helps individuals, families, businesses, and agencies support charitable causes throughout Chelan, Douglas, and Okanogan counties.

Douglas County Waste Management Environmental Studies College Scholarship

The Douglas County Waste Management Environmental Studies College Scholarship was established in 2005 to support Douglas County students seeking further education in environmental engineering or the area of environmental sciences. The committee seeks to award students who plan to major in one of these fields at an accredited educational program in the United States.

The Karl A. Bickel and Madira Bickel Journalistic Scholarship Fund supports journalism education by providing grants to accredited colleges and universities with journalism programs. Established from Karl A. Bickel's Last Will and Testament, the fund aims to assist deserving students in their pursuit of journalism, ensuring they receive the necessary financial backing to succeed in their studies and future careers.

The SPFFA Educational Scholarship provides financial support of $5000 for university candidates aiming to teach French in primary and secondary schools. To be eligible, applicants must be American citizens or resident aliens, preferably enrolled in a School of Education and pursuing a Master in Teaching with a focus on French. Additionally, applicants need to maintain a GPA above 3.00, ensuring commitment to their educational goals.

The Community Foundation of NCW is a tax-exempt philanthropic organization that helps individuals, families, businesses, and agencies support charitable causes throughout Chelan, Douglas, and Okanogan counties.

Jerry Van Winkle Memorial Scholarship

Jerry Van Winkle always considered himself a lifelong learner. One of his finest qualities was the ability to find a way to achieve his goals. He pursued his desire to become a counselor, beginning his Masters’ Degree studies at age 55. Jerry’s greatest joy was in helping students see the possibilities that education could provide. He would be honored to know that his wish – to assist students in pursuing their education – will be carried out through this scholarship fund. Each year this scholarship honors a student that demonstrates financial need, strong moral character, and personal growth throughout high school.

The Community Foundation of NCW is a tax-exempt philanthropic organization that helps individuals, families, businesses, and agencies support charitable causes throughout Chelan, Douglas, and Okanogan counties.

Fern Cousineau Duncan Art Scholarship

Mrs. Duncan was an art teacher at Wenatchee High School from 1929 to 1959. She also taught at Wenatchee Valley College until she retired. This scholarship, established by Ms. Duncan’s will, supports graduating seniors from North Central Washington, with special emphasis on students who are pursuing a career in the field of art. As part of the application process, students must submit a portfolio of their work, which is reviewed by a panel of local artists.

The Victory Project - Emerging Sports Leaders Scholarship Fund

Five (5) Emerging Sports Leaders Scholarships will provide financial assistance to students whose lives have been impacted by the sport of soccer. This scholarship is available for high school seniors with post-secondary education plans at a university, college, trade, or vocational school. Participation in collegiate soccer is not required. Payment will be made directly to the school.

Award

• $5,000.00

The New Century Scholars Research Grant, offered by the American Speech-Language-Hearing Foundation, provides up to four grants of $25,000 each to support innovative research in communication sciences and disorders. This funding opportunity encourages both experienced and new investigators to explore novel ideas and methodologies, including artificial intelligence applications. Researchers must demonstrate potential for independent research, with a focus on significant contributions to the field. Applications are due after completing an Intent to Submit Form by March 5.

The Ms. Molly Foundation provides essential support for domestic violence victims through the Local Shelter/Agency Support Grant. Established in 1996, the foundation aims to raise awareness and assist local agencies committed to helping victims find safety and empowerment. Eligible applicants include 501(c)(3) nonprofit shelters that partner with Molly Maid franchises. By addressing the cycle of violence, the foundation strives to create healthier family environments and restore hope to those affected.

The Researcher–Practitioner Collaboration Grant, offered by the American Speech-Language-Hearing Foundation, supports collaborations between researchers and practitioners focused on improving services for individuals with communication disorders. Grants of $35,000 are available for studies that address clinical problems and enhance evidence-based practices. This funding opportunity encourages partnerships aimed at translating research into practical applications, thereby fostering innovative solutions in communication sciences and disorders within healthcare and educational settings.

The NIDCR Predoctoral to Postdoctoral Transition Award aims to enhance the diversity of the dental, oral, and craniofacial research workforce. This program supports exceptional graduate students from underrepresented backgrounds as they transition from PhD or dual degree programs (F99) to mentored postdoctoral positions (K00). Key deadlines for applications span from August 2024 to April 2027, ensuring ample opportunities for eligible candidates to apply.

CultureSource

CultureSource is a member association for non-profit arts and cultural organizations in Southeast Michigan serving Wayne, Oakland, Macomb, Washtenaw, Livingston, Monroe and St. Clair counties. As a regional service organization, we do this work through hosting professional development workshops that grow creative and leadership capacities, presenting programs that provide space for exchanging ideas about arts and culture, and leading initiatives that bring together stakeholders interested in the public accessing creative expression.

Our MISSION is to advance and cultivate creative and cultural expression in Southeast Michigan.

The Spector Craft Prize for Emerging Artists

The Spector Craft Prize (the “Prize”) is an annual initiative launched in 2025 to champion excellence in American craft. Founded by Abigail Klem Spector and Warren Spector through the Spector Family Foundation, the program supports craft artists at pivotal moments in their careers through awards, mentorship, and community-building.

In an era dominated by rapid technological advancement, the Spector Craft Prize stands as a vital counterbalance by preserving material connections in an increasingly virtual world, supporting creative expression amid declining public funding for arts education, and reconnecting makers and the public to our shared heritage of craft. By championing craft artists at pivotal moments in their careers, the Spector Family Foundation aims to strengthen the role of craft in contemporary American culture.

Aim of the Prize

The Spector Craft Prize for Emerging Artists seeks to identify and support exceptional emerging craft artists whose work demonstrates technical mastery, innovative vision, and deep engagement with American culture. The Prize aims to recognize artists who show significant potential for contributing to the field and who would benefit from the comprehensive support provided by the program.

Selected artists represent the future of American craft and demonstrate a commitment to strengthening craft's role in contemporary American culture through their practice, community engagement, and artistic vision. 

Stark Community Foundation is one of the area’s major sources of college scholarship support— thanks to the generosity of caring individuals, families and businesses that have created scholarship funds.

The Foundation currently manages more than 100 scholarship funds that support hundreds of deserving students each year from Stark and Carroll counties. In 2025, more than $1,000,000 was awarded to local students to help them achieve their educational dreams.

The Church of Christ (Christian Disciples) Memorial Scholarship Fund

The Church of Christ (Christian Disciples) Memorial Scholarship Fund was established to help students who have permanent residence in Carroll County, Ohio or had a permanent residence on the date they began their post high school education.

Coral Gables Community Foundation

Led by community leaders, the Coral Gables Community Foundation provides the philanthropic conduit to connect individuals and corporations looking to positively impact the success of the community. Now in its 33rd year, the Foundation has been at the forefront of the evolving needs of Coral Gables while effectively bringing together beneficiaries and benefactors to fund programs with the greatest impact and benefit to “The City Beautiful.”

Coral Gables Community Foundation’s Scholarships Program

Coral Gables Community Foundation is honored to partner with our fundholders to administer generous scholarships as well as manage the Foundation’s own scholarship funds.

The Foundation and its fundholders have proudly awarded over $6.7 million in scholarships in just the last decade.

High-Achieving Four-Year Scholarship

This 4-year scholarship is given annually to students who have demonstrated overall academic achievement and dedication to service within the school and in his/her community, and have low family income. The Foundation also considers applicants’ motivation, financial need, and personal experiences.

Maintenance

In order to maintain the scholarship each year, the recipient must maintain a minimum overall 3.0 GPA throughout his/her college studies.

Outreach Foundation Helen Bonser Scholarship

This scholarship supports the educational aspirations of individuals from Spokane and Kootenai Counties who identify as LGBTQA+ or Allies, helping them achieve their academic and career goals while fostering a sense of community engagement. 

Applicants should demonstrate exceptional character, leadership, and/or LGBTQA+ community involvement. Recipients are eligible to re-apply and compete for the Outreach Foundation Helen Bonser Scholarship after a waiting period of 5 years.

Newport Priest River Rotary & Howard Wildin Education Scholarship

Scholarships and individual awards to achieve a specific objective will be made in the form of grants to students, apprentices or interns participating in a training program, internship, or apprenticeship to prepare them for gainful employment in a recognized occupation that is not prohibited under federal or state law. Such grants will be awarded to individuals to improve or enhance a vocational skill; and develop specialized skills or knowledge in literary, artistic, musical, scientific, teaching or other similar skills or talents.

The FWW Research Award supports innovative, short-term studies aimed at enhancing women's health, particularly in areas such as cardiovascular disease, female cancers, and hormonal impact on health. Eligible applicants include MDs and PhDs affiliated with accredited institutions. The program prioritizes research with direct clinical applications and seeks proposals that promise to attract additional funding for further study. Notably, sociological research is excluded from funding consideration.

Each year, Innovia awards over $400,000 in scholarships to deserving students like you who are college-bound or pursuing vocational or technical training. Single scholarship awards range between $500 and $4,000.

Eilleen Hutchison Scholarship

Primary factors for consideration are academic achievement, financial need and good personal character. Previous recipients of this award are eligible to reapply.

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Grace Brooks and E. Perry Palmer Scholarship (Claflin) ($2,300)

This renewable scholarship is available to from high schools in the Community Foundation’s 11-county service area (Calhoun, Clarendon, Fairfield, Kershaw, Lee, Lexington, Newberry, Orangeburg, Richland, Saluda, and Sumter). 

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Gerhard Metzen Scholarship ($2,200) 

This renewable scholarship is for current or incoming students at Midlands Technical College (MTC) in Columbia, SC for a degree or certificate program. 

About our scholarships

We partner with Civic Federal Credit Union to provide both professional development and student scholarships.

Over many years, the scholarships have provided nearly $3.5 million to credit union members to further their education. This investment not only advances the professional development and educational goals of Civic members, but also strengthens the communities they serve — amplifying their leadership impact and deepening their ability to drive meaningful change across North Carolina.

Civic Foundation Scholarship

Each year, Civic proudly awards $5,000 scholarships to 25 Civic members who are graduating high school seniors and are planning to attend a four-year college or university. These one-time scholarships are paid directly to the student’s school in a single installment and may be applied toward tuition, textbooks, computers, or other educational expenses.

The Craig H. Neilsen Foundation's Creating Opportunity & Independence Grant supports programs and research that enhance the quality of life for individuals with spinal cord injuries (SCI). It welcomes applications from nonprofit organizations and rehabilitation facilities in the U.S. and Canada, focusing on projects that foster independence, community participation, and capacity-building. Priority is given to initiatives that demonstrate broad impact and involve individuals with SCI, ensuring their needs and perspectives shape the proposed activities.

The Alcon Foundation Grant aims to enhance eye care services and improve patient access, with a focus on educational and training programs. The foundation also supports cultural and community development initiatives that uplift the quality of life in areas where Alcon operates, including cities like Fort Worth, Houston, and Irvine. However, it does not fund non-501(c)(3) organizations, athletic leagues, or fundraising events, among other exclusions.