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Best Large Grants for Nonprofit Organizations in South Carolina

Find the perfect Large Grants for Nonprofit Organizations in South Carolina on Instrumentl. 9,000+ Large Grants for Nonprofit Organizations in South Carolina in the United States.

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$3.79B

Total funding

$5K

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9,000+ grants
$3.79B total
$5K median

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9,315 Results based on applied filters

Oldham Little Church Foundation Grant

Oldham Little Church Foundation
Private
United States
US $10,000 - US $15,000
The Oldham Little Church Foundation Grant, established in 1949, has awarded over $53.56 million in facility completion grants to small evangelical Protestant churches across the U.S. The foundation aims to support church renovations and new construction projects, enhancing their ability to serve their communities. Grants typically range from $10,000 to $15,000 and are considered quarterly. Eligible churches must meet specific criteria, including membership size and financial stewardship, to qualify for funding.
Protestantism

Drops of Hope Giving Program

Vapur
Corporate
Countries
Unspecified amount in in-kind support
The Drops of Hope Giving Program, initiated by Vapur, aims to enhance environmental sustainability by reducing single-use plastics. This initiative collaborates with organizations to donate thousands of reusable bottles globally, promoting access to clean water. Eligible applicants include registered 501(c)3 nonprofit organizations or those offering marketing opportunities in exchange for contributions. The program reflects Vapur's commitment to innovative, portable products that inspire active lifestyles, fostering a healthier planet.
Sanitation & Clean Drinking Water

George L. Mosse Prize in European Intellectual and Cultural History

American Historical Association
Association/Society
United States
US $1,000
The George L. Mosse Prize, awarded by the American Historical Association, honors exceptional works in European intellectual and cultural history since 1500. This prestigious award, with a prize amount of $1,000, recognizes scholarly distinction and originality. Eligible submissions include books published in 2024, with a focus on research accuracy and literary merit. Winners will be announced on the AHA website in October 2025 and celebrated at the January 2026 AHA annual meeting in Chicago.
European History Community Culture & Heritage

Presbyterian Committee on the Self–Development of People Grant Program

Synod of the Mid-Atlantic
Association/Society
Panama, United States
Unspecified amount
The Presbyterian Committee on the Self-Development of People Grant Program supports projects led by economically disadvantaged communities to combat poverty and injustice. By promoting justice, building stronger communities, and advocating for economic equity, this program empowers individuals and groups to address the root causes of their struggles. The initiative seeks sustainable solutions that respect the environment and reject violence, fostering long-term positive change in society.
Economic Rights, Justice, & Mobility Community Development & Revitalization Social Justice / Human Rights

Carpenter Foundation - Asian Art Grant

E. Rhodes and Leona B. Carpenter Foundation
Private
China, Taiwan, Republic Of China +1 more
Unspecified amount
The E. Rhodes and Leona B. Carpenter Foundation, established in 1975, supports public charities with a focus on Asian art, performing arts in Richmond, VA, and graduate theological education. The Foundation prioritizes requests from organizations with historical ties to the Carpenters and those promoting LGBTQ+ inclusion and community health. It aims to enhance cultural exchange through art exhibitions, particularly in the US and China, while excluding support for private education and large public charities.
Asian Art

Glen C. Smith Jr./KCC Caddie Scholarship

Kalamazoo Community Foundation
Private
United States
More than US $1,000

Kalamazoo Community Foundation

Fueling Equity & Racial Justice Since 1925

KZCF is dedicated to our mission to create a thriving community where people, resources and expertise are mobilized to advance racial, social and economic justice in Kalamazoo County.

Scholarships & Education Grants

For All Levels of Education After High School

Kalamazoo Community Foundation is dedicated to creating pathways to higher education so students can thrive in their academic pursuits and for a lifetime. We oversee more than 60 scholarships and education grants (many of which are multiyear awards) for college, graduate school, career training and more.

Glen C. Smith Jr./KCC Caddie Scholarship

The Glen C. Smith Jr./KCC Caddie Scholarship was established at the Kalamazoo Community Foundation in 1985 by the Kalamazoo Country Club Caddie Committee in honor of Glen Smith, Jr. The purpose of the scholarship is to provide scholarship assistance to young people in qualified caddie programs at member clubs of the Golf Association of Michigan and the Western Golf Association.

Multiyear Award; Renews Annually

Education - Higher Education Vocational & Trade Education

High on Heroes Scholarship

Kalamazoo Community Foundation
Private
United States
More than US $500

Kalamazoo Community Foundation

Fueling Equity & Racial Justice Since 1925

KZCF is dedicated to our mission to create a thriving community where people, resources and expertise are mobilized to advance racial, social and economic justice in Kalamazoo County.

Scholarships & Education Grants

For All Levels of Education After High School

Kalamazoo Community Foundation is dedicated to creating pathways to higher education so students can thrive in their academic pursuits and for a lifetime. We oversee more than 60 scholarships and education grants (many of which are multiyear awards) for college, graduate school, career training and more.

High on Heroes Scholarship

The High on Heroes Scholarship was established in 1993 by High on Heroes Inc. (a local air show) to provide scholarship assistance for post-high school education for family members of law enforcement, firefighters, public safety, and emergency personnel employed in Kalamazoo County. Special consideration will be given to applicants who are related to persons who died while employed by a qualifying agency. Even greater consideration may be given to applicants related to an employee who died in the line of duty. Additional application materials are required for this scholarship.

Multiyear Award; Renews Annually

Education - Higher Education Vocational & Trade Education

Annual Grants: Public Policy Requests

John William Pope Foundation
Private
United States
Unspecified amount
The John William Pope Foundation offers annual grants to support public policy research promoting a free-market economy and individual liberty under the rule of law. Emphasizing the importance of property rights and personal initiative, the foundation welcomes proposals from tax-exempt organizations, particularly those impacting public policy in North Carolina. By focusing on long-term solutions rather than short-term aid, the foundation aims to empower communities and foster sustainable economic growth.
Governance & Democracy Public Policy

Jerry A. & M. Christine Walker Scholarship

Kalamazoo Community Foundation
Private
United States
US $1,000

Kalamazoo Community Foundation

Fueling Equity & Racial Justice Since 1925

KZCF is dedicated to our mission to create a thriving community where people, resources and expertise are mobilized to advance racial, social and economic justice in Kalamazoo County.

Scholarships & Education Grants

For All Levels of Education After High School

Kalamazoo Community Foundation is dedicated to creating pathways to higher education so students can thrive in their academic pursuits and for a lifetime. We oversee more than 60 scholarships and education grants (many of which are multiyear awards) for college, graduate school, career training and more.

Jerry A. & M. Christine Walker Scholarship

The Jerry A. and M. Christine Walker Scholarship was established in 2019 by Christine Walker. The purpose of the fund is to provide financial assistance for Kalamazoo County residents or persons who have graduated from a school within Kalamazoo County to help them reach their goals of increased financial independence through employment. Additional application materials are required for this scholarship.

Multiyear Award; Renews Annually

Education - Higher Education Vocational & Trade Education

Pershing Square Sohn Cancer Prize

Pershing Square Sohn Cancer Research Alliance (PSSCRA)
Association/Society
United States
US $750,000
The Pershing Square Sohn Cancer Prize is awarded to early-career scientists in the New York area who are pursuing innovative cancer research. Established by the Pershing Square Foundation in partnership with The Sohn Conference Foundation, the prize offers $250,000 annually for up to three years. With a commitment of over $49 million since 2013, the Alliance aims to accelerate cancer cures by fostering collaborations between academia and industry, providing a unique network and access to vital resources for groundbreaking research.
Cancer / Oncology

Americana Foundation: American Heritage Grant

Americana Foundation
Private
United States
Unspecified amount
The Americana Foundation's American Heritage Grant aims to support projects that broaden inclusivity in early American art and narratives, especially for underrepresented groups. Recognizing the historical significance of Americana, the foundation prioritizes initiatives that promote understanding and appreciation of America's diverse heritage. Eligible applicants include nonprofit organizations and municipal entities. The foundation encourages innovative projects that reinterpret early American material culture, fostering a deeper connection to the past for future generations.
Art Conservation Historic Preservation

Wade & Clio Van Valkenburg Scholarship

Kalamazoo Community Foundation
Private
United States
Unspecified amount

Wade & Clio Van Valkenburg Scholarship

The honorable Wade Van Valkenburg was a Circuit Court judge in Kalamazoo for six years. He was concerned about the youth in this community, especially those who have had to overcome circumstances or obstacles that may otherwise hinder them from seeking training or higher education. This scholarship fund was established in 2004 through the Wade Van Valkenburg Trust to provide educational scholarships for Kalamazoo County students facing financial hardship or challenges in their education due to past legal issues or accusations. Additional application materials are required for this scholarship.

KZCF scholarships may be applied to any items under your school’s cost of attendance (COA). Each school has a different COA that may include items such as tuition, fees, housing, transportation, food, health insurance, etc. Scholarship payments are sent directly to your institution. 

This scholarship is a one-time award, meaning that it will not repeat in subsequent years. The money awarded can be applied to your education costs alongside other scholarships or funding that you may receive, and there are no necessary steps once funds are sent.

Education - Higher Education Vocational & Trade Education

Rare Organic Acidemias Research Consortium (ROAR)- Early Career Fellowship

Rare Diseases Clinical Research Network (RDCRN)
Federal Government
United States
Up to US $50,000

Rare Organic Acidemias Research (ROAR) Consortium Early Career Fellowship

The overall mission of the ROAR career enhancement core is to recruit and retain a cohort of physicians, physician-researchers, and other researchers with clinical research expertise in rare metabolic disorders, specifically organic acidemias.

 Annual funding of $50,000 (total cost, including indirect costs) is available to support a postdoctoral trainee or early career faculty member (within 5 years of residency or fellowship training as of proposed start date of either June 1, 2026 or October 1, 2026) for a one-year period. The ROAR Consortium intends to fund 1-2 awards this cycle with one award starting by June 1, 2026 and another starting by October 1, 2026. 

Trainees are expected to complete the following:

  • Design and complete a clinical research project focusing on organic acidemias. This project can leverage existing projects within the ROAR consortium or can be a new project unrelated to existing projects in the consortium. Of note, funds cannot be used to support research projects involving animal models. 
  • Meet monthly with their project mentor and periodically with the ROAR Career Enhancement Core leadership to discuss progress.
  • Provide a progress report within 30 days of completing the program.
  • Attend ROAR consortium activities including the monthly ROAR team calls and annual ROAR consortium in-person meeting.
  • Present their project at the annual ROAR consortium in-person meeting or monthly ROAR team call.
  • Acknowledge the ROAR consortium support on manuscripts published upon completion of the project.
  • Trainees are expected to participate in the RDCRN Rare Disease Research Training Program.
  • Trainees are encouraged to budget funds for travel to one conference relevant to the organic acidemia and/or rare disease community to present their work. 
Rare Diseases

L.L.Bean - Club Fostered Stewardship Grant

American Canoe Association (ACA)
Association/Society
United States
Up to US $2,000

Since 2002, the ACA has partnered with L.L. Bean to sponsor the Club Fostered Stewardship (CFS) Program. The CFS Program provides funding to local and regional paddling clubs and organizations that undertake stewardship projects on waterways in their area. The purpose of the program is to encourage paddling clubs to take an active role in protecting and improving the nation's waterways. 

Many of the stewardship needs of our nation's waters are best addressed at the local and regional level. Paddling clubs and watershed organizations are in an ideal position to lead these efforts. These paddlers are often willing to volunteer their time and assist with local stewardship projects. However, clubs often lack the funds needed to pay project expenses. As a result, they miss an opportunity to leverage dozens and sometimes hundreds of volunteer hours that could improve conditions on their favorite waterway.

CFS Grant Program

That is why L.L. Bean and the ACA have teamed up to sponsor the CFS Program.

CFS grants are available for projects that utilize volunteers in efforts to protect, maintain or restore recreational waterways, to provide for or improve public access, or to enhance safe navigation. 

Grant amounts range from $100-$1,000.

Past projects receiving CFS grants include:

  • Removing heavy debris and trash from rivers and bays in numerous locations throughout the U.S.
  • Improving access for local paddlers
  • Establishing water trails 
  • Water quality monitoring 
  • Environmentally-sensitive woody debris removal 
  • Riparian buffer restoration and improvement 
  • Environmental education and outreach programs

ACA also offers additional assistance to clubs and organizations for waterway stewardship projects. Clubs and organizations concerned about liability for injuries that occur during stewardship projects may be able to obtain liability insurance coverage through the ACA. Clubs may request additional assistance using the It is not mandatory to be a paddling club to apply. In the past, grants have been awarded to conservation organizations and watershed groups.

Want to learn more about projects that have been funded through the CFS program? Review reports from past years!

Recreational Water Use & Boating

Linda K. Freeland Early Childhood Education Scholarship

Greater Salina Community Foundation
Private
United States
Unspecified amount

Greater Salina Community Foundation

Our mission is to build permanent endowment funds and meet charitable community needs. The Foundation achieves its mission by:

  • Enabling donors to fulfill their charitable desires
  • Increasing the capacity of nonprofit organizations to fulfill their individual missions
  • Facilitating prudent management and care of funds
  • Promoting community philanthropy through education
  • Providing affiliate services to neighboring communities
  • Meeting needs through grants, scholarships, and pass-through funds

Scholarship Program

The community foundation offers a wide variety of scholarships for students, provided by the generosity of local donors. Whether you are a high school senior, a current college student, or a non-traditional student we work with donors to help you take the next step in your education.

Linda K. Freeland Early Childhood Education Scholarship

For High school senior from Saline County, KS, with an intended major of early childhood education.

Applicant must submit an essay that states why they have chosen to major in early childhood education.

Renewals

  • This award is not renewable.

Education - Higher Education Education - Preschool / Early Learning

Marcella Dowling Oakes Art Scholarship

Greater Salina Community Foundation
Private
United States
Unspecified amount

Greater Salina Community Foundation

Our mission is to build permanent endowment funds and meet charitable community needs. The Foundation achieves its mission by:

  • Enabling donors to fulfill their charitable desires
  • Increasing the capacity of nonprofit organizations to fulfill their individual missions
  • Facilitating prudent management and care of funds
  • Promoting community philanthropy through education
  • Providing affiliate services to neighboring communities
  • Meeting needs through grants, scholarships, and pass-through funds

Scholarship Program

The community foundation offers a wide variety of scholarships for students, provided by the generosity of local donors. Whether you are a high school senior, a current college student, or a non-traditional student we work with donors to help you take the next step in your education.

Marcella Dowling Oakes Art Scholarship

For students qualifying for graduation from a high school within the service area of GSCF or its affiliates with an intended major in an art field, including, but not limited to, visual arts, fine arts education, digital/graphic arts, architecture, or design.

 Applicants must submit a personal statement about how they will utilize their drawing skills to accomplish their future career goals.

Renewals

  • This award is not renewable.

Education - Higher Education Art Education

Japanese-Language Learners Event Grant

United States-Japan Foundation
Private
United States
Up to US $1,000
The Japanese-Language Learners Event Grant, offered by the Japan Foundation, Los Angeles, provides financial support of up to $1,000 for events that promote Japanese language education across various educational levels. This grant aims to motivate learners through contests and presentations, encouraging participation from multiple schools in the region. Eligible expenses include judge fees, venue costs, and production materials, while closed events for single schools are not supported.
Education Cross-Cultural Understanding & Exchanges Linguistics

Eric Minkiewicz Presidential Scholarship Award

The Community Foundation for the Greater Capital Region
Private
United States
Unspecified amount

The Community Foundation for the Greater Capital Region

Who We Are

Empowering generous people with meaningful giving opportunities.

Since 1968, The Community Foundation for the Greater Capital Region (CFGCR) has been dedicated to improving the quality of life in the Greater Capital Region. We work with — and for — all our neighbors across the community because together, we are stronger.

Eric Minkiewicz Presidential Scholarship Award

This scholarship is available to eligible employees of Renewal by Andersen of Eastern NY and their immediate family members who plan to pursue a two or four year college degree or a trade/technical certification program.

We support students who live our values: who do what they say they will, act with urgency, respect others, work as a team and commit to continuous improvement.

This scholarship reflects our belief that everyone leads, and our commitment to fostering a winning environment for our employees, customers, and community.

Education - Higher Education Vocational & Trade Education

Ottawa County Community Foundation: Steve and Patricia Baccus Scholarship Fund

Greater Salina Community Foundation
Private
United States
More than US $1,000
The Ottawa County Community Foundation manages the Steve and Patricia Baccus Scholarship Fund, aimed at supporting students graduating from high schools in Minneapolis or Bennington, KS. This scholarship is designed for those pursuing further education at accredited institutions and is funded by local donors. While the foundation promotes community philanthropy, it does not offer renewal options for this scholarship, encouraging students to seek ongoing educational opportunities.
Education - Higher Education Vocational & Trade Education

AHA Predoctoral Fellowship

American Heart Association
Association/Society
United States
Up to US $69,548
The AHA Predoctoral Fellowship aims to enhance research and clinical training for pre-doctoral students pursuing careers in cardiovascular health. Applicants must be enrolled in a relevant doctoral program and demonstrate collaboration with a mentor. The fellowship provides an annual stipend of $28,224, plus health insurance support and project funding. Eligible candidates are full-time students who have completed initial coursework and can commit to research efforts. This opportunity fosters the development of independent researchers in the field.
Cardiovascular Diseases & Systems

Established Investigator Award

American Heart Association
Association/Society
United States
US $550,000
The Established Investigator Award from the American Heart Association supports established investigators at the associate professor level, emphasizing innovative research in cardiovascular and cerebrovascular sciences. With a budget of $80,000 per year and a maximum award of $400,000 over five years, it aims to enhance the careers of candidates demonstrating significant accomplishments and promising research directions. Eligibility requires a doctoral degree and a full-time faculty position, with specific criteria for appointment levels and funding history.
Cardiovascular Diseases & Systems

SVS Student Research Fellowship

Society for Vascular Surgery (SVS) Foundation
Association/Society
Canada, United States
US $3,000
The SVS Student Research Fellowship, offered by the Society for Vascular Surgery Foundation, supports undergraduate and medical students in the U.S. and Canada conducting vascular research. The fellowship emphasizes hypothesis-driven projects, providing a $3,000 award and a complimentary Journal of Vascular Surgery subscription. It aims to enhance students' education while fostering innovative solutions in vascular health, ensuring inclusivity and diversity in applicant eligibility.
Cardiovascular Diseases & Systems

National Register Internship Travel Scholarship

National Register of Health Service Psychologists
Private
Canada, United States
US $1,000
The National Register Internship Travel Scholarship, funded by the American Psychological Foundation, offers financial assistance to psychology doctoral students for relocation to their predoctoral internship sites. This scholarship supports diverse applicants who are in good standing in accredited programs and have secured internships recognized by the APA or CPA. By alleviating relocation costs, the scholarship aims to facilitate the professional development of future psychologists.
Psychology

Purple Heart Gary Gutelius Memorial Scholarship

Community Foundation Of Mahoning Valley
Private
United States
Unspecified amount

About Us

Leadership. Collaboration. Impact.

The Community Foundation of the Mahoning Valley helps philanthropists support the causes closest to their heart while connecting local residents to the resources they need for a better quality of life.

Our Mission

To serve as a leader and advocate for strategic philanthropy, partnering with donors to anchor a permanent and growing endowment and making investments in the Mahoning Valley that improve the quality of life for all residents.

Scholarship Opportunities

Your Community, Your Support System

Our community members support hundreds of local students every year through various scholarships facilitated by the Community Foundation of the Mahoning Valley.

Education - Higher Education Military & Veterans Services

CORE Funding: AHNS Presidential Award: Defining and Implementing Value-Based Care in Head and Neck Cancer

American Academy of Otolaryngology - Head & Neck Surgery Foundation
Private
Canada, United States
Up to US $15,000
The American Academy of Otolaryngology–Head and Neck Surgery Foundation is inviting proposals for the CORE Funding: AHNS Presidential Award, aimed at enhancing value-based care in head and neck oncology. This initiative focuses on improving quality, efficiency, and patient outcomes through data-driven strategies. Key proposal components include quality and process measures, along with identifying care gaps. Priority areas include behavioral health integration and innovative contracting models, promoting scalable solutions that enhance care quality and value in this specialty.
Cancer / Oncology Otorhinolaryngology

Paul E. Henkin School Psychology Travel Grant

American Psychological Foundation Inc
Private
United States
US $1,000
The Paul E. Henkin School Psychology Travel Grant, offered by the American Psychological Foundation, provides up to $1,500 for student members of APA Division 16. This funding helps cover registration, lodging, and travel expenses for attending the APA Annual Convention. It encourages applicants from diverse backgrounds and requires a commitment to a career in school psychology. Eligible applicants must be current student members of APA Division 16 and cannot use the funds for food or materials not included in registration.
Psychology

Division 39 Marsha D. McCary Fund Grant for Psychoanalysis

American Psychological Foundation Inc
Private
United States
US $13,500
The Division 39 Marsha D. McCary Fund Grant for Psychoanalysis aims to enhance public understanding of psychoanalysis and its applications in various fields. This grant supports initiatives that promote psychoanalytic education, research, and services, especially benefiting early career professionals and underserved populations. The American Psychological Foundation encourages applicants from diverse backgrounds to apply, ensuring a broad representation within the field. This initiative fosters the ongoing development of psychoanalysis as a vital discipline in psychology.
Psychology

Large Grants for Nonprofit Organizations in South Carolina Highlights

Looking for large grants for nonprofit organizations in South Carolina?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in South Carolina recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Large Grants for Nonprofit Organizations in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

54 Large Grants for Nonprofit Organizations in South Carolina over $25K in average grant size

41 Large Grants for Nonprofit Organizations in South Carolina over $50K in average grant size

32 Large Grants for Nonprofit Organizations in South Carolina supporting general operating expenses

100+ Large Grants for Nonprofit Organizations in South Carolina supporting programs / projects

1,000+ Grants on Instrumentl focused on Health Care Access & Delivery

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
26.6%
Q3
24.1%
Q4
20.4%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$530,911 $530.9 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081