Best Large Grants for Nonprofit Organizations in South Carolina

The Rachael Ray Save Them All Grants support innovative projects aimed at enhancing the lifesaving efforts for cats and dogs in U.S. shelters. Eligible organizations, including public and private shelters and rescue groups, can apply for up to $50,000 to fund initiatives like intake prevention services, medical care for at-risk pets, and shelter enrichment programs. All projects must align with the mission of increasing adoption rates and improving animal welfare within the Best Friends Network.

The National Institute on Aging intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Coordinating Center (CC) of the Claude D. Pepper Older Americans Independence Centers (OAIC) program. The CC serves as a facilitator for OAIC site interactions and as a conduit for translating OAIC objectives and findings to both scientific and general audiences. The proposed CC must demonstrate an ability to work cooperatively with all OAIC sites and possess sufficient scientific expertise in geriatrics and related areas to serve the national coordination functions of the OAIC program. Applicants should have a demonstrated ability to coordinate multi-site projects.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.

Our Mission

The Community Foundation of Western Massachusetts seeks to enrich the quality of life of the people of our region by:

• Encouraging philanthropy
• Developing a perpetual, flexible endowment
• Assessing and responding to emerging and changing needs
• Serving as a resource, catalyst, and coordinator for charitable activities
• Promoting efficiency in the management of charitable funds

The Scholarship Program

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. 
• Most scholarships are for students who live in Franklin, Hampshire, and Hampden Counties. However, some are also available to students who live in Berkshire County and Hartford County in Connecticut.
• We offer scholarships to those who attend on either a full-time or part-time basis. 
• Any student who plans to enroll for the upcoming fall semester, in any year of college as an undergraduate or graduate student and who will attend an accredited post-secondary school in the United States may apply.
• Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

Stanley Ciejek, Sr. Scholarship Fund

Supporting residents of Franklin, Hampden and Hampshire Counties

Our Mission

The Community Foundation of Western Massachusetts seeks to enrich the quality of life of the people of our region by:

• Encouraging philanthropy
• Developing a perpetual, flexible endowment
• Assessing and responding to emerging and changing needs
• Serving as a resource, catalyst, and coordinator for charitable activities
• Promoting efficiency in the management of charitable funds

The Scholarship Program

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. 
• Most scholarships are for students who live in Franklin, Hampshire, and Hampden Counties. However, some are also available to students who live in Berkshire County and Hartford County in Connecticut.
• We offer scholarships to those who attend on either a full-time or part-time basis. 
• Any student who plans to enroll for the upcoming fall semester, in any year of college as an undergraduate or graduate student and who will attend an accredited post-secondary school in the United States may apply.
• Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

Ruth L. Brocklebank Memorial Scholarship Fund

Supporting African American graduates of Springfield high schools.

The Wagner Catholic Scholarship, offered by the Community Foundation of the Holland/Zeeland Area, supports graduating seniors from local Catholic parishes who are pursuing higher education. Eligible applicants must demonstrate financial need and faith commitment through a personal essay. The scholarship is renewable for up to three years, with a decreasing award amount after the first year. This initiative aims to empower students to further their education while fostering community values.

Selkirk Pickleball Growth Program

At Selkirk, we are committed to growing the sport of pickleball by making it accessible to everyone. The Selkirk Growth Program enables schools and community programs worldwide to access Selkirk equipment.

Our original goal was to give away 3,000+ paddles a year; we have now given away more than 40,000 paddles since we started in 2019. As part of our Growth Program, we are donating gently-used paddles to:

Schools.

• First responders.
• Senior centers.
• Churches.
• Parks & recreation departments.
• Other community organizations looking to expand their programs.

We will also provide a discount on additional paddles, balls, and nets for schools and charities involved in the program.

Our Mission

The Community Foundation of Western Massachusetts seeks to enrich the quality of life of the people of our region by:

• Encouraging philanthropy
• Developing a perpetual, flexible endowment
• Assessing and responding to emerging and changing needs
• Serving as a resource, catalyst, and coordinator for charitable activities
• Promoting efficiency in the management of charitable funds

The Scholarship Program

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. 
• Most scholarships are for students who live in Franklin, Hampshire, and Hampden Counties. However, some are also available to students who live in Berkshire County and Hartford County in Connecticut.
• We offer scholarships to those who attend on either a full-time or part-time basis. 
• Any student who plans to enroll for the upcoming fall semester, in any year of college as an undergraduate or graduate student and who will attend an accredited post-secondary school in the United States may apply.
• Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

Ronald A. Copes Scholarship Fund

Supporting graduating high school seniors from Springfield, MA or Hartford, CT who have a minimum GPA of 3.0 and who indicate participation in extracurricular activities.

Our Mission

The Community Foundation of Western Massachusetts seeks to enrich the quality of life of the people of our region by:

• Encouraging philanthropy
• Developing a perpetual, flexible endowment
• Assessing and responding to emerging and changing needs
• Serving as a resource, catalyst, and coordinator for charitable activities
• Promoting efficiency in the management of charitable funds

The Scholarship Program

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. 
• Most scholarships are for students who live in Franklin, Hampshire, and Hampden Counties. However, some are also available to students who live in Berkshire County and Hartford County in Connecticut.
• We offer scholarships to those who attend on either a full-time or part-time basis. 
• Any student who plans to enroll for the upcoming fall semester, in any year of college as an undergraduate or graduate student and who will attend an accredited post-secondary school in the United States may apply.
• Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

Permelia A. Butterfield Scholarship Fund

Supporting students, under 21 years of age, with one or both parents deceased, all Christian religious sects and denominations and who are residents of Franklin County; preference for the Town of Orange.

Our Mission

The Community Foundation of Western Massachusetts seeks to enrich the quality of life of the people of our region by:

• Encouraging philanthropy
• Developing a perpetual, flexible endowment
• Assessing and responding to emerging and changing needs
• Serving as a resource, catalyst, and coordinator for charitable activities
• Promoting efficiency in the management of charitable funds

The Scholarship Program

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. 
• Most scholarships are for students who live in Franklin, Hampshire, and Hampden Counties. However, some are also available to students who live in Berkshire County and Hartford County in Connecticut.
• We offer scholarships to those who attend on either a full-time or part-time basis. 
• Any student who plans to enroll for the upcoming fall semester, in any year of college as an undergraduate or graduate student and who will attend an accredited post-secondary school in the United States may apply.
• Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

Luther A. and Evelyn L. Belden Memorial Scholarship Fund

Supporting graduating high school seniors who are residents of Hatfield, MA, or graduating seniors of Smith Academy. If no qualified applicants meet these criteria, then any qualified applicant who is a graduating senior and a resident of Hampshire County shall be considered.

Our Mission

The Community Foundation of Western Massachusetts seeks to enrich the quality of life of the people of our region by:

• Encouraging philanthropy
• Developing a perpetual, flexible endowment
• Assessing and responding to emerging and changing needs
• Serving as a resource, catalyst, and coordinator for charitable activities
• Promoting efficiency in the management of charitable funds

The Scholarship Program

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. 
• Most scholarships are for students who live in Franklin, Hampshire, and Hampden Counties. However, some are also available to students who live in Berkshire County and Hartford County in Connecticut.
• We offer scholarships to those who attend on either a full-time or part-time basis. 
• Any student who plans to enroll for the upcoming fall semester, in any year of college as an undergraduate or graduate student and who will attend an accredited post-secondary school in the United States may apply.
• Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

John DiNapoli Memorial Scholarship Fund

Supporting Hampden County high school seniors; preference for residents of Holyoke.

Our Mission

The Community Foundation of Western Massachusetts seeks to enrich the quality of life of the people of our region by:

• Encouraging philanthropy
• Developing a perpetual, flexible endowment
• Assessing and responding to emerging and changing needs
• Serving as a resource, catalyst, and coordinator for charitable activities
• Promoting efficiency in the management of charitable funds

The Scholarship Program

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. 
• Most scholarships are for students who live in Franklin, Hampshire, and Hampden Counties. However, some are also available to students who live in Berkshire County and Hartford County in Connecticut.
• We offer scholarships to those who attend on either a full-time or part-time basis. 
• Any student who plans to enroll for the upcoming fall semester, in any year of college as an undergraduate or graduate student and who will attend an accredited post-secondary school in the United States may apply.
• Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

James W. Colgan Loan, Bank of America, Trustee

$3K Maximum awarded. Supporting current Massachusetts residents who have resided in-state for a minimum of five years

Our Mission

The Community Foundation of Western Massachusetts seeks to enrich the quality of life of the people of our region by:

• Encouraging philanthropy
• Developing a perpetual, flexible endowment
• Assessing and responding to emerging and changing needs
• Serving as a resource, catalyst, and coordinator for charitable activities
• Promoting efficiency in the management of charitable funds

The Scholarship Program

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. 
• Most scholarships are for students who live in Franklin, Hampshire, and Hampden Counties. However, some are also available to students who live in Berkshire County and Hartford County in Connecticut.
• We offer scholarships to those who attend on either a full-time or part-time basis. 
• Any student who plans to enroll for the upcoming fall semester, in any year of college as an undergraduate or graduate student and who will attend an accredited post-secondary school in the United States may apply.
• Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

George and Theresa Crete Scholarship Fund

Supporting residents of western Massachusetts

The ASM Minority Travel Award aims to enhance diversity in microbial sciences by supporting faculty from underrepresented institutions, including community colleges and historically black colleges. This initiative ensures that diverse perspectives are included in the field, fostering a richer academic environment. Awardees receive complimentary registration and housing for ASM Microbe 2026, promoting professional development and networking opportunities in microbiology.

Our Mission

The Community Foundation of Western Massachusetts seeks to enrich the quality of life of the people of our region by:

• Encouraging philanthropy
• Developing a perpetual, flexible endowment
• Assessing and responding to emerging and changing needs
• Serving as a resource, catalyst, and coordinator for charitable activities
• Promoting efficiency in the management of charitable funds

The Scholarship Program

The Community Foundation of Western Massachusetts administers over 160 scholarships. Some of the funds help students from a particular school or area; others provide financial assistance to those pursuing a specific field of study; still others assist students that are most in need. Students who apply to the Scholarship program may be eligible for many of these funds.

• Scholarships may be used to offset tuition, fees, room and board, and other items included as part of the cost for attending the institution. 
• Most scholarships are for students who live in Franklin, Hampshire, and Hampden Counties. However, some are also available to students who live in Berkshire County and Hartford County in Connecticut.
• We offer scholarships to those who attend on either a full-time or part-time basis. 
• Any student who plans to enroll for the upcoming fall semester, in any year of college as an undergraduate or graduate student and who will attend an accredited post-secondary school in the United States may apply.
• Scholarships are provided for one academic year and are not automatically renewed each year. You can reapply to our program every year you are going to attend college, and the application you submit that year will be considered for all scholarships for which you are eligible.

Florence Blish Scholarship Fund

Supporting residents of Agawam to attend college

The Ann B. Zekauskas Family Foundation is committed to supporting qualified 501(c)(3) organizations that align with our mission and values. We welcome grant requests from nonprofit organizations seeking to make a meaningful impact in their communities in the areas of nutritional education, food access, or the advancement of cuilnary arts careers. 

Special Giving Program

Throughout her life, Ann B. Zekauskas supported numerous nonprofits and charitable endeavors. She especially had a fondness for organizations that worked to rescue and rehome abandoned animals — and her house was always home to a dog, a cat, and, for a very long time, a set of parakeets. 

In honoring Ann’s complete legacy, each year our trustees contribute to select causes which are of special personal importance to them and fall beyond our three main areas of giving. These include supporting educational institutions; local community groups and projects; athletics programs; animal rescues; and more.

The 1772 Foundation, in collaboration with the National Preservation Partners Network, is opening its 2026 grant cycle for Historic Property Redevelopment Programs (HPRP). This initiative aims to support nonprofit organizations in the U.S. focused on historic property revitalization. Eligible organizations must hold a 501(c)(3) designation and be NPPN members. Grants typically range from $50,000 to $75,000, promoting sustainable practices that address community revitalization and heritage conservation.

The NSF National Quantum Virtual Laboratory - Quantum Testbeds initiative aims to enhance U.S. leadership in quantum science and technology. By fostering collaboration among researchers, industry partners, and diverse talent, this program seeks to accelerate the development and implementation of quantum technologies. It emphasizes translational research, education, and outreach, ensuring broad engagement across sectors. Proposals must follow established design and implementation deadlines to contribute effectively to the overarching goals of the National Quantum Initiative.

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Ted Vanden Bosch Scholarship for the Children of Police Officers, Firefighters, and Rescue Personnel

• Graduating senior or graduating early college student who attends public, private, or home school in the primary service area of the Community Foundation or in Fennville, Hamilton, or Saugatuck
• Enrolling at an accredited post-secondary school within the United States
• Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• GPA of 3.0 or greater
• Child of a firefighter, police officer, or rescue personnel
• Special consideration given to candidates interested in pursuing a degree in the sciences

Bill Boehlke Scholarship

Bill Boehlke worked for both the Seattle Seahawks and Seattle SuperSonics as a creative member of their digital communications departments. His imagination, humor and positive personality were appreciated by everyone he worked with. In memory of Bill, his family established this scholarship fund in 2020. The fund will provide scholarships to high school seniors in the state of Washington who are pursuing a career in digital communications, including social media video production. Scholarships will help cover qualified expenses including tuition, books and other expenses necessary for their classes. Scholarships are not renewable. Special consideration will be given to students based on financial needs and the applicant’s history of good character and community service.

Amount:

$1,000 - $5,000

ASPCApro.org provides tools and resources for animal welfare professionals, veterinary personnel and volunteers. We take a progressive approach to helping the country's at-risk animals, promoting cutting edge research to advance the field.

ASPCA The Rescue Effect Campaign Grants

The American Society for the Prevention of Cruelty to Animals® (ASPCA®) is offering up to $2 million in grants to support adoption at shelters and rescues during the 2026 “The Rescue Effect”, a nationwide campaign that highlights the positive chain of events that occurs when people adopt, foster, volunteer, advocate and donate.

The Rescue Effect will run through the months of August, September, and October 2026, during which grantees must offer a minimum of two (2) fee-waived adoption days/events each month. 

Restrictions and Parameters

Grant funds may be used for any of the following:

• make-ready costs for cats/dogs available for adoption during the Campaign months covered by the grant term (e.g., s/n surgery, microchips, vaccinations, testing, dewormer, flea-tick treatment, heartworm preventative, bloodwork)
• marketing/advertising costs (e.g., adoption promotions, volunteer/foster recruitment)
• waived adoption fees for adoptions occurring during the Campaign months covered by the grant term
• foster program expansion/ramp up
• operating costs related to supporting participation in The Rescue Effect campaign

About Us

We help shelters and rescue groups save pets.

Saving pets. Together.

The Petfinder Foundation has been helping animal shelters and rescue groups since 2003. We are the ONLY national organization that does nothing but give cash and product grants to adoption groups.

Operation Grant

Grants vary depending on the organization’s need to support the number of adoptable pets listed on Petfinder and are awarded on a monthly basis throughout the year until all funds are depleted.

Community Foundation of the Holland/Zeeland Area

Our Mission

The Community Foundation of the Holland/Zeeland Area seeks to ensure that our community thrives today, tomorrow, and forever by building our Community’s Endowment to support high impact charitable projects, helping donors achieve their charitable goals, and leading and partnering in community-level initiatives.

Scholarships

CFHZ awards over $1 million in scholarships each year for students to attend schools of higher education throughout the nation. Our scholarships are possible thanks to the generosity of donors who invest in our community’s future by furthering the education of others.

All Holland/Zeeland area individuals interested in post-secondary education are encouraged to apply for CFHZ scholarships.

The Foundation proudly administers over 100 scholarships, each with unique eligibility criteria that must be met before a candidate can be considered.

Shelley Speet-Mills Creative Arts Scholarship

• Graduating senior or graduating early college student who attends public, private, or home school in the primary service area of the Community Foundation
• Enrolling at an accredited post-secondary school within the United States
• Financial need (must submit the page of the FAFSA Submission Summary showing the Student Aid Index amount)
• GPA of 3.0 or greater
• Planning to pursue a career in the arts
• Recommended by applicant’s high school art teacher
• This scholarship is potentially renewable and supports one student at a time. 

The Community Foundation of Marquette County distributes over $130,000 annually in scholarships to benefit aspiring students in Marquette County.

William B. Larson Memorial Scholarship

Provides scholarships for graduating seniors of Ishpeming, Negaunee, and Westwood High Schools. The Fund aims to award three scholarships of equal amount annually to eligible applicants based on the following criteria: Students must be graduating seniors pursuing higher education in the field of business administration, they must demonstrate financial need, and have a GPA of 3.0 or higher.

Distribution Process

• CFMC scholarship recipients will be contacted in June requesting student enrollment verification
• Scholarships can only be distributed once student’s information is received
• Scholarships will be distributed to the college/school/university indicated by student
• The scholarship must be used for tuition and fees required for the enrollment or attendance of the student at a qualifying educational institution; fees, books, supplies, and equipment required for courses of instruction at such an educational institution; and room and board, within the first semester of first year of students enrollment
• That year’s recipient must claim the scholarship within that fiscal year to be distributed (by 12/31/xx)

The JSF Scholarships aim to empower economically disadvantaged students by providing financial assistance for their education. This initiative addresses barriers to education and employment, enabling students to achieve academic success and meaningful careers. The Foundation supports various scholarship programs, partnering with schools and universities, and focusing on areas such as financial need and mentorship. By fostering educational opportunities, the JSF Scholarships contribute significantly to community development and individual empowerment.

In just one application, our Common Scholarship Application provides students access to more than 150 scholarship opportunities with awards ranging from $1,000 to more than $5,000.

In 2025, San Diego Foundation awarded a record-breaking $5.5 million in scholarships to nearly 1,400 students.

William and Lucille Ash Scholarship

Be adult re-entry students (age 25 or older) or former foster youth who plan to enroll full-time at an accredited four-year university, community college or licensed career/technical school in the United States in fall (preference may be given to students attending a school in California).

The ICRG Seed Grant supports innovative research aimed at understanding and treating gambling disorders. With a focus on pilot studies, secondary data analysis, and developing new methodologies, it encourages both established and early-career researchers to apply for funding up to $40,000. The grant emphasizes the importance of addressing critical issues in gambling research while ensuring the inclusion of diverse participant groups. This initiative aims to enhance public education and promote responsible gaming practices.

The NewSchools: Innovative Schools Grant supports education leaders aiming to create new public and charter schools that address the unique needs of today's students. With funding ranging from $150,000 to $250,000, the grant emphasizes equity and innovative educational models. Applications are encouraged before the December 10, 2024 priority deadline, with the final deadline on January 8, 2025. This initiative seeks to empower diverse communities through transformative educational solutions.