Best Large Grants for Nonprofit Organizations in South Carolina

The Curriculum and Instruction Honor Award, presented by SHAPE America, recognizes outstanding contributions to health and physical education curriculum research. This prestigious award highlights the importance of effective instructional practices that prepare students for active and healthy lives. Award recipients are selected based on their scholarship in health education and physical education, demonstrating commitment to excellence since the organization's founding in 1885. SHAPE America advocates for quality education and promotes the well-being of preK-12 students across the United States.

This funding opportunity aims to enhance a web-based ordering portal for distributing 1.5 million HIV and STI self-tests to high-burden communities. By optimizing access to these self-tests, the initiative seeks to raise awareness, prevent new infections, and improve the health outcomes of users, thereby contributing to better overall public health and wellbeing.

The Trail Accelerator Grants aim to enhance mountain bike trail communities by providing essential planning and design services. With funding between $10,000 to $30,000, these grants support local organizations in creating sustainable trail systems. The initiative encourages projects that increase access and promote community engagement, particularly focusing on diversity and inclusion. Applicants must demonstrate the capacity to match funds, ensuring collaborative efforts to improve trail networks and experiences for all riders.

The Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement aims to enhance the effectiveness of HIV prevention and care planning for RWHAP Parts A and B recipients. Through the provision of training, tools, and technical assistance, this initiative seeks to optimize resource allocation and strengthen the overall system of HIV care and treatment, ultimately improving health outcomes for those affected by HIV.

This funding opportunity aims to support Early Stage Investigators (ESIs) in conducting preclinical HIV/AIDS research using Nonhuman Primate (NHP) models. Eligible applicants must have at least two years of postdoctoral experience and be within ten years of their terminal degree. The initiative aligns with the NIH Strategic Plan for HIV and HIV-Related Research, targeting the reduction of HIV incidence, development of therapies, and advancement in research areas related to HIV.

The ABPN Faculty Innovation in Education Award aims to support innovative educational projects that enhance residency training and lifelong learning for psychiatrists and neurologists. With a funding potential of $120,000 over two years, the award prioritizes projects focused on Diversity, Equity, and Inclusion, clinical skills evaluations, and professional competence. Applicants must hold a faculty position at an accredited U.S. medical school or submit a validated offer letter. Preference is given to first-time applicants and those at junior or mid-faculty levels.

The AIDS Drug Assistance Program (ADAP) Emergency Relief Funds aim to provide essential funding to states and territories. This initiative focuses on preventing, reducing, or eliminating waiting lists for ADAP services, ensuring timely access to necessary medications and support for individuals living with HIV/AIDS. This program addresses critical funding shortfalls, enhancing the healthcare infrastructure and improving health outcomes in affected communities.

The Ryan White HIV/AIDS Program Part C Capacity Development Program aims to enhance the capabilities of community-based organizations, focusing on improving health outcomes and decreasing HIV transmission. This initiative supports individuals who have not yet accessed regular HIV care, emphasizing innovative care solutions and infrastructure development to address these critical needs.

The HIV Care Grant Program, funded by the US HHS: Health Resources & Services Administration (HRSA), aims to enhance access to high-quality HIV care and treatment for low-income individuals. This initiative supports states and territories in developing comprehensive systems to address the needs of those living with HIV. By providing essential resources, the program seeks to improve health outcomes and ensure that vulnerable populations receive the necessary support and services.

The Grief Reach grant program, supported by the New York Life Foundation and the National Alliance for Children's Grief, invites innovative community expansion proposals to better serve grieving children. Eligible organizations can apply for funding up to $160,000 to enhance their programs, focusing on unique community needs. By collaborating with the Judi's House/JAG Institute, participants will receive essential training and resources for impactful program evaluation, fostering a supportive environment for children and families facing grief.

The Grief Reach: Changemaker Supported Community Expansion Cycle offers up to $110,000 to enhance community programs for grieving children. Organizations are encouraged to innovate and expand their services to better meet community needs. The initiative, in partnership with the Judi’s House/JAG Institute, emphasizes training and resources for effective program evaluation over a three-year period, culminating in impactful community expansion projects.

RRCU Gives Foundation Grant

Mission Statement:

RRCU Gives strengthens our region by providing meaningful financial support to nonprofits addressing hunger, housing, and financial education. Through our annual grant awards and major funding initiatives, we help local organizations grow, thrive, and create lasting change.

 We award grants annually, with applications in June and awards in August.

Focus Areas

• Hunger
• Housing
• Financial Education

The AGA-Bern Schwartz Family Fund Research Scholar Award in Pancreatic Cancer provides $100,000 annually for three years to early-career faculty focused on independent research in pancreatic cancer. This award aims to protect at least 50% of the recipient's time for research activities. Eligible applicants must hold an MD or PhD and be classified as early-career. The award encourages physician-scientists and underrepresented groups in biomedical research to apply, supporting innovative research that can lead to significant advancements in understanding pancreatic cancer.

Nurses Educational Funds

Nurses Educational Funds, Inc. depends solely on donations to advance our only mission, to promote nursing leadership through annual scholarship support for professional nurses seeking masters and doctoral degrees in nursing education, practice, research, and administration.

NEF’s only purpose is to provide nursing scholarship assistance to make graduate level nursing education possible. NEF is one of the largest, national, private, professionally endorsed source of funds for advanced nursing study with over one hundred years of service to and for professional nursing. NEF is a non-profit organization with 501(c) status.

Rita Reis Wieczorek Scholarship for Maternal-Infant and Pediatric Nursing

Created in 2020, by Rita Reis Wieczorek, EdD, RN, PNP, FAAN, together with NEF. Dr. Wieczorek is an NEF Board Member Emeritus and longtime board member. This scholarship is the first NEF Scholarship to focus on maternal-infant and pediatric nursing. For over four decades Dr. Wieczorek has devoted her career to providing the best maternal-infant and pediatric care to her patients as well as teaching the highest standards of care to master's and doctoral nursing students, motivating them to excel in their care for the well-being of mothers, infants and children.

Request for Proposals

Community Care Corps encourages organizations across the country to apply for 18-month grants ($30,000–$200,000) to develop and scale innovative volunteer programs that provide nonmedical assistance to older adults, adults age 18 and older with disabilities and family caregivers.

Projects funded through this initiative will increase the number of community-based volunteer programs available to provide nonmedical assistance while decreasing the number of older adults, adults with disabilities, and family caregivers who need assistance in maintaining independence in the community but are unable to obtain help. In doing so, the initiative will strengthen community-based supports that help people maintain independence, reduce unmet needs, and improve overall well-being.

The National Institute of Allergy and Infectious Diseases (NIAID) is calling for applications for four Leadership and Operations Centers (LOCs) as part of its HIV/AIDS Clinical Trials Network initiative. These LOCs will guide research on HIV therapeutics, prevention, and treatment strategies across diverse populations. The initiative aims to enhance evidence-based practices and improve health outcomes for individuals affected by HIV, ultimately contributing to the goal of ending the HIV epidemic.

The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for up to four Clinical Trials Network Laboratory Centers (LCs). These LCs will support HIV prevention and treatment strategies by providing necessary laboratory infrastructure and technologies for clinical trials. They will ensure rigorous laboratory testing and oversight, enhance sample integrity, and utilize advanced data management systems to meet evolving demands in HIV research and testing.

The Rural Decentralized Water System Grant Program aims to assist low to moderate-income individuals in financing household water wells and decentralized wastewater systems. This program provides grants to eligible nonprofit organizations to create a revolving fund for loans and sub-grants. Funds can be utilized for constructing, refurbishing, or replacing water well and wastewater systems, ensuring safe and efficient water management for rural communities.

The National Institute of Allergy and Infectious Diseases (NIAID) is launching a funding opportunity for Clinical Trials Units (CTUs) as part of its effort to combat HIV/AIDS. This initiative aims to support innovative clinical trials and implementation research to improve prevention and treatment strategies. With a focus on both domestic and international research sites, CTUs will play a crucial role in addressing the HIV epidemic and enhancing participant recruitment and retention. This funding opportunity is authorized under the Public Health Service Act.

Jack Kent Cooke Foundation

The Jack Kent Cooke Foundation is dedicated to advancing the education of exceptionally promising students who have financial need. Since 2000, the Foundation has awarded $304 million in scholarships to more than 3,400 students from 8th grade through graduate school, along with comprehensive academic advising, career pathway counseling and other support services. The Foundation has also provided $136 million in grants to organizations that serve such students.

The Jack Kent Cooke Foundation’s scholarship programs are designed to encourage and support outstanding students who work hard and have financial need. Our scholarships provide financial assistance and academic support to high school, undergraduate, and graduate students. In addition to the monetary award, students join a thriving network of more than 3,400 Cooke Scholars.

Young Scholars Program

The Cooke Young Scholars Program is a selective five-year, pre-college scholarship for exceptionally promising 7th grade students with financial need. It provides comprehensive academic and college advising, as well as financial support for school, Cooke-sponsored summer programs, internships, and other learning enrichment opportunities.

Program Experience

Educational Advisers support Young Scholars to maximize high school experiences and to go on to thrive at the nation’s top-performing colleges. Our programming and support may include:

• Identifying an appropriately rigorous high school.
• Engaging in four-year planning and goal-setting.
• Funding for academic and extracurricular opportunities, such as music and art lessons, supplemental academic classes and technology.
• Annual summer programs, including two required Young Scholar programs.
• Year-round Young Scholars community programming.
• Networking opportunities with a high-achieving peer community.

The Senator Harold "Potch" Wheeler Memorial Scholarship, managed by the Community Foundation of Whitley County, honors the legacy of a dedicated public servant. This competitive scholarship is available annually to high school seniors from Whitley County who plan to pursue college education in public service or within the Indiana Department of Natural Resources. Recipients are chosen based on their embodiment of the ideals and character traits exemplified by Senator Wheeler.

The CDC's Comprehensive Suicide Prevention Program for States aims to enhance public health approaches to suicide prevention across the U.S. By targeting high-risk groups, such as veterans and rural populations, the program utilizes data to identify prevention areas, assess existing programs, and implement evidence-based strategies. Key outcomes include improved partner engagement and a measurable reduction in suicide rates. This initiative allows potential applicants to prepare by reviewing relevant data and forming strategic partnerships ahead of future opportunities.

Indigo Hope Foundation: At-Risk Youth Development Grant

Empowering programs that provide mentorship, education, life skills training, and opportunities for young people facing challenges.

Key Focus Areas:

• Mentorship Programs
• Educational Support
• Life Skills Training
• Career Development

Example Programs We Fund:

• After-school tutoring and mentorship
• Job readiness training
• Leadership development

The Indigo Oak Fund's Education Grant Program supports educational initiatives in Colorado and the Bay Area, focusing on both traditional schools and alternative learning experiences. This program aims to empower individuals through education, fostering personal growth and lifelong learning. By funding resources for teachers and career advancement for adults, the Fund seeks to create equal opportunities, enhance community engagement, and contribute to a more equitable society.

Carl Hill Memorial Scholarship

Awards:

• One time award of $500.

The Stem Cell Grants: Travel Award supports students, postdocs, and faculty attending scientific conferences and workshops related to stem cell research. Up to $1,200 is available for each application, with a maximum of two applications per PI lab each calendar year. Priority is given to those presenting at stem cell meetings and workshops. All applications must be submitted at least one week before travel to ensure funding consideration.

The 1890 Scholarships Program, overseen by the USDA's National Institute of Food and Agriculture (NIFA), aims to enhance the recruitment and retention of undergraduate and graduate students at 1890 Land-grant institutions. It supports students pursuing degrees in food and agricultural sciences, fostering a skilled workforce in this critical sector. By providing scholarships, the program encourages academic excellence and commitment to the agricultural field, ultimately contributing to the development of future leaders in food systems.