Best Large Grants for Nonprofit Organizations in South Carolina

CHEJ Small Grants Program

The Small Grants Program has officially relaunched. Applications are now open.The Center for Health, Environment & Justice’s (CHEJ) Small Grants Program is for grassroots groups working on environmental health and justice issues related to the presence of “toxics” (toxic chemicals or hazardous substances) in their immediate communities. CHEJ prioritizes community-based organizations aiming to have local, state and regional impact through their own strategies and actions.

The Huether/Gillan Scholarship, established by the Niskayuna Community Foundation, supports community-minded students from Niskayuna or its school district. This need-based scholarship aims to assist those pursuing higher education while emphasizing academic achievement and community service. Mr. Huether initiated this scholarship in honor of his parents, promoting values of dignity, diversity, impact, inclusion, innovation, and integrity. Interested applicants should contact Mr. Vince Bianchi for further details.

The Michael Hurewitz Scholarship, offered by The Community Foundation for the Greater Capital Region, supports high school seniors in the region who have a passion for journalism and demonstrate financial need. This scholarship aims to empower students by providing them the necessary financial assistance to pursue their educational goals in journalism, fostering the next generation of storytellers and communicators in our community.

The Viola Pfaff Bowman Memorial Scholarship, offered by the Hamilton County Community Foundation, supports high school students in Hamilton County, particularly those from Hamilton Heights, Noblesville, Sheridan, and Westfield High Schools. Candidates must be pursuing a degree in communications or business and demonstrate financial need. This scholarship honors Viola Pfaff Bowman, a dedicated alumna who inspired many through her involvement in school media. It encourages students with media program experience to apply.

The Dr. Susan Holstine Behavioral Health Professions Scholarship, established in 2022 by the Chuckanut Health Foundation, honors Dr. Holstine's commitment to accessible behavioral health services. This scholarship aims to support local students pursuing careers in behavioral health, alleviating financial barriers and empowering the next generation. By investing in education, we strengthen our community and encourage future leaders in mental health care.

The Marion Kellum Performing Arts Scholarship, administered by the Crown Point Community Foundation, aims to support graduating high school seniors pursuing a Bachelor of Fine Arts or related degrees. Applicants must have a minimum 3.0 GPA and documented involvement in at least five theatre productions. This non-renewable scholarship provides essential financial assistance to nurture talent in the performing arts, enhancing the cultural landscape of South Lake County.

The Hays, Colin, Legacy Scholarship, administered by the Beatrice Educational Foundation, offers financial assistance to deserving graduating seniors of Beatrice High School. With one to three scholarships available, totaling no more than $2,000, applicants must demonstrate strong academic performance, with a minimum GPA of 3.5. This initiative supports students in their pursuit of higher education, fostering academic excellence and community engagement in the Beatrice School District.

The Thomas Halbert Scholarship, administered by the Community Foundation of the Ozarks, offers a $1,400 scholarship to undergraduate nursing students enrolled in accredited colleges in Springfield, MO. Applicants must demonstrate financial need through FAFSA and provide a transcript showing a minimum GPA of 3.0. An essay submission is also required. This initiative reflects the foundation's commitment to enhancing community quality of life through education and support.

The Protect the Farm Scholarship, offered by the Community Foundation of the Ozarks, provides a $1,000 award for graduating high school seniors from select schools in Missouri. This scholarship is renewable for up to three years, provided students maintain a 2.5 GPA and pursue a major in agriculture. Applicants must be enrolled in a minimum of 12 credit hours at an accredited institution. Required materials include a transcript, personal essay, and recommendation letter.

The Allen Butler Minority Law Enforcement Scholarship Fund, established by the Duluth African American Men’s Group, supports young people of color from Duluth pursuing law enforcement training at post-secondary institutions. This initiative honors Allen Butler, a dedicated Duluth police officer. The scholarship aims to empower eligible applicants who have graduated from local high schools or earned GEDs, demonstrating a commitment to community engagement and academic achievement in Criminal Justice or Law Enforcement.

The AAAAI Foundation Faculty Development Award provides $300,000 in funding over three years to support the growth of junior faculty in the fields of allergy and immunology. This initiative, spearheaded by the American Academy of Allergy, Asthma & Immunology, aims to foster the development of future leaders and independent researchers dedicated to combating asthma and allergic diseases through impactful research.

The Chrysalis Project Program, hosted by the American Academy of Allergy, Asthma & Immunology (AAAAI), offers an exciting opportunity for U.S. and Canadian medical students and residents to explore the field of allergy and immunology. Participants can attend the AAAAI Annual Meeting free of charge, enhancing their understanding and interest in this vital subspecialty. This initiative aims to cultivate the next generation of allergists, fostering professional growth and engagement in allergy and immunology.

The Melanoma Research Alliance is offering the Exchange Patient Forum Scholarship for 2026, aimed at melanoma patients, survivors, and caregivers. This scholarship includes travel support for attending a one-day forum in Washington, DC, designed to empower participants with the latest research and treatment insights. The event fosters connections within the melanoma community, featuring networking opportunities and collaboration with leading experts, ensuring participants leave with valuable knowledge and support.

The Blue Mountain Community Foundation Common Scholarship supports current high school seniors and graduates from Walla Walla, Columbia, Garfield, or Umatilla County who have been residents for at least three consecutive years. It also includes adults residing in these counties and those working in the wine industry or pursuing degrees at the University of Idaho or WSU. This scholarship simplifies the application process by allowing students to apply once for multiple scholarships.

The Adult Learner Scholarship by College Now Greater Cleveland supports adult students aged 19 and older who have interrupted their education. Eligible applicants must be pursuing a first bachelor’s degree, associate’s degree, or a vocational certificate. This renewable scholarship, which ranges from $1,500 to $2,000 annually, is available for up to five years or until degree completion. Applicants must meet GPA requirements and reside in specific Northeast Ohio counties, ensuring access to education for returning learners.

The AVID: Priscilla and Ranney Draper Scholars Fund offers scholarships to high school seniors enrolled in the AVID elective, supporting their transition to a four-year college or university. Administered by Scholarship America, this program recognizes students from Orange County, CA, who have demonstrated commitment and financial need. Each applicant completes a single application for multiple scholarships, with awards of up to $5,000 available for undergraduate studies.

The Dr. Jim and Betsy Bobenhouse Scholarship, established in 2026, supports graduating high school seniors from Lancaster County, Nebraska, who plan to pursue a degree in education or healthcare at a Nebraska college or university. The scholarship aims to encourage students with a GPA of 3.0 or above who are actively involved in extracurricular activities and demonstrate financial need. This initiative reflects the commitment of the Lincoln Community Foundation to foster educational opportunities in the community.

The McKnight Endowment Fund for Neuroscience offers the Neurobiology of Brain Disorders Award to support innovative research aimed at understanding and treating brain disorders. It provides up to four awards of $100,000 each year for three years, encouraging proposals that explore biological mechanisms and environmental contributions to neurological disorders. The program emphasizes inclusivity and collaboration among researchers to advance the field and improve therapeutic interventions for conditions such as Alzheimer's and Parkinson's disease.

The Sloan Indigenous Graduate Partnership (SIGP) Scholarship Program, funded by the A.P. Sloan Foundation, aims to support Indigenous graduate students in STEM fields. This program, a collaboration among the Montana University System institutions, offers scholarships, professional development, and networking opportunities to enhance the academic journey of Indigenous students. With awards of $20,000 for M.S. and $40,000 for Ph.D. candidates, the SIGP seeks to increase the number of Indigenous scholars earning advanced degrees in science and engineering.

The AACR-Torrey Coast Foundation Transpacific Gastric and Esophageal Cancer Research Partnership Grant supports innovative research on upper gastrointestinal malignancies, which are responsible for over one million deaths globally in 2023. This grant encourages collaboration between U.S. and Asian institutions, focusing on resistance, metastasis, and novel treatment strategies. Proposals should detail plans for clinical translation and are open to researchers at all career stages, especially those new to upper GI cancer research.

The Bernice M. Brightbill Fund Scholarship offers a one-time award to a senior female student from the Central Dauphin School District pursuing a college degree in business studies. This scholarship aims to support students demonstrating financial need, regardless of citizenship or documentation status. Eligible applicants can apply for multiple scholarships and may be selected for any or all they qualify for, promoting accessibility in education.

The Pediatric Oncology Student Training (POST) Program Grant, offered by Alex’s Lemonade Stand Foundation, aims to foster the next generation of pediatric oncology researchers. This summer internship provides undergraduate, graduate, and medical students with hands-on research experience in a supportive environment, focusing on diversity and inclusion. Grants will specifically support students from underrepresented communities in the scientific workforce, enabling impactful research and mentorship opportunities to advance pediatric cancer care.

The Eash-Potter Scholarship supports LGBTQ youth in central Pennsylvania, honoring Melinda Eash and Sharon Potter's legacy. It is available to graduating high school seniors from specific counties who demonstrate commitment to enhancing the community climate for LGBTQ+ individuals. Financial need is a consideration, and the scholarship is a one-time award. Students of color, transgender individuals, and children of LGBTQ+ parents are particularly encouraged to apply, promoting diversity and inclusion within the scholarship program.

The Douglas W. Pfautz Memorial Scholarship Fund honors a dedicated community servant and family man, Doug Pfautz. Sponsored by the Rotary Club of Elizabethtown, this scholarship supports high school seniors from the Elizabethtown Area School District who demonstrate good moral character and a commitment to community service. Applicants must maintain good academic standing and plan to pursue further education. This one-time award encourages students to embody the Rotary motto of 'Service Above Self', continuing Doug's legacy of service.

The Lynn E. Poffenberger Memorial Scholarship Fund, established by the Middle Paxton Lions Club, honors the legacy of Mr. Poffenberger by providing annual scholarships to two graduating seniors. Eligible applicants must reside in Middle Paxton Township or Dauphin Borough, demonstrate financial need, and show active community involvement. This one-time scholarship aims to support deserving students in their educational pursuits, reflecting the values of service and commitment to the community.

The Skyler James Wenger Scholarship, established in 2012 in memory of Skyler, a 14-year-old who tragically lost his life, supports graduating seniors from Cedar Cliff or Red Land High School. Eligible applicants must plan to attend college or trade school, come from a single-parent household, be athletes, and demonstrate financial need. This one-time award aims to honor Skyler's legacy by helping deserving students achieve their educational goals.

The Steven C. Leuthold Family Foundation Grants support 501(c)(3) non-profits in areas such as land conservation, environmental protection, human services, and animal welfare. Founded in 1991 by philanthropist Steven C. Leuthold, the foundation prioritizes organizations that align with its giving preferences. Applications are due by June 30, 2025, with grants distributed by December 2025. Note that incomplete applications will not be accepted.