Best Large Grants for Nonprofit Organizations in South Carolina

The ABC Law Centers: Birth Injury Lawyers Cerebral Palsy Scholarship awards $1,000 annually to a deserving student with cerebral palsy. This scholarship aims to raise awareness about cerebral palsy and celebrate the accomplishments of individuals affected by it. Applicants must be enrolled in a U.S. higher education institution and maintain a GPA of 3.0 or higher. The scholarship reflects ABC Law Centers' commitment to supporting those impacted by birth injuries and ensuring their futures are secure.

The Carter Creech Scholarship offers financial support up to $8,000 for graduating seniors of Troy Buchanan High School in Missouri who aim to pursue a four-year degree. Eligible candidates must maintain a minimum 3.5 GPA, achieve an ACT score of 27 or higher, and rank in the top 10% of their class. This scholarship encourages academic excellence and allows recipients to reapply annually for up to $32,000 over four years, fostering educational opportunities in the community.

The Charles E. Crow Memorial Scholarship Fund, established in 1953, supports graduates of Big Pasture High School in Randlett, Oklahoma, by providing a one-year scholarship up to $5,000. This initiative aims to enhance educational opportunities for students pursuing college, community college, or trade school certifications. Applicants must demonstrate financial need and maintain a minimum GPA of 2.8. By investing in the potential of local youth, this fund contributes to building thriving communities and advancing equity in education.

The Apraxia Kids Childhood Apraxia of Speech (CAS) Clinical Research Grant focuses on funding high-quality research applicable to childhood apraxia of speech. With an award of up to $50,000, it supports studies addressing early diagnosis, treatment approaches, and the impact of CAS on literacy and phonological skills. Apraxia Kids encourages proposals that consider diverse populations and comorbid conditions, aiming to enhance understanding and outcomes for children with CAS.

The PERF: Infrastructure/Registry Research Grant focuses on developing new multicenter infrastructures or enhancing existing programs in pediatric neurology. It aims to advance clinical research, particularly in pediatric epilepsy, supporting projects that train and mentor young investigators. The grant offers up to $300,000 for a duration of three years, with an emphasis on mentorship for both senior and early-stage investigators, ensuring the growth of expertise in the field.

The Nordstrom Community Grant focuses on supporting youth and families by providing over $1 million in grants annually. It aims to assist grassroots organizations that address essential community needs such as food, shelter, and clothing, as well as creating opportunities for economic mobility through mentorship and workforce development. Eligible organizations must be 501(c)(3) nonprofits located in areas where Nordstrom operates. Applications are encouraged for those meeting these criteria.

The Mike Cox Internship Scholarship, established by the Duncan Aviation Family Trust, honors the late Mike Cox's legacy of mentorship. This scholarship supports students at accredited institutions who demonstrate a passion for growth and excellence. A maximum of two scholarships are awarded annually, providing $1,000 per recipient for educational expenses. Eligible candidates must be full-time students and have completed or participated in the Duncan Aviation internship program, ensuring a commitment to education and the aviation industry.

The Native Forward Student Access Funding supports American Indian and Alaska Native students by providing financial assistance for graduate and professional examination costs. With over 50 years of experience, Native Forward has empowered more than 22,000 students across the United States. This funding not only covers exam fees but also related preparatory expenses, ensuring that students can pursue their educational goals without financial barriers. The initiative aims to enhance representation and visibility of Native scholars in higher education.

The Music Teachers of Excellence (MToE) Award, managed by the CMA Foundation, recognizes outstanding public-school music educators. This prestigious award, with a $5,000 prize, aims to support teachers who inspire students and enrich their communities through music education. The application will open on September 3, 2025, allowing full-time music teachers with at least four years of experience to showcase their commitment and impact in the field. Stay tuned for more details!

The MSU Graduate Teaching Scholarships recognize the vital role graduate students play in undergraduate education by providing financial support for their teaching efforts. Eligible candidates must have a graduate teaching assistantship, complete professional development, and apply before the semester starts. Scholarships range from $250 to $1000, promoting excellence in teaching and enriching the educational experience at Montana State University.

The Bertha Parker Cody Award, offered by the Society for American Archaeology, supports Native American, Alaska Native, and Native Hawaiian women pursuing undergraduate or graduate studies in archaeology and museum studies. This scholarship fosters educational advancement and collaboration between archaeologists and Indigenous communities, promoting ethical practices and cultural preservation. Funded in part by the Autry Museum of the American West, it aims to empower diverse voices within the field of archaeology and is available annually.

The NIA Academic Leadership Career Award (K07) provides funding for established investigators to strengthen research capacity in aging and Alzheimer's Disease. The program supports the development of educational infrastructure, mentorship, and career development activities. Key deadlines for applications include February 12, June 12, and October 12 from 2025 to 2027. This award is specifically for research not involving independent clinical trials, allowing applicants to gain experience in trials led by others.

The Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program aims to foster the development of American Indian and Alaska Native scientists by funding eligible Tribal Entities. This initiative focuses on creating effective training and mentoring activities for individuals pursuing doctoral degrees in biomedical research. Ultimately, it seeks to enhance the capability of researchers to address health disparities within AI/AN communities, ensuring culturally appropriate and ethically responsible research practices.

The Jon Christopher Gauss, Jr. Wrestling Scholarship Fund, established by his parents, supports high school wrestlers pursuing post-secondary education at accredited institutions. This initiative, part of the Community Foundation of Washington County MD, aims to honor Jon's legacy while empowering students to achieve their educational goals. The scholarship enhances community engagement and provides vital financial assistance to promising athletes, ensuring that their dedication to wrestling translates into academic success.

The Quinn Alec Hoover Legacy Scouting America Scholarship Fund supports graduating seniors from Scouting America in the Mason Dixon District, encompassing Washington County, MD, and parts of Pennsylvania. Established by the Community Foundation of Washington County, this scholarship honors the legacy of Quinn Alec Hoover, aiming to recognize and assist students who embody the values of scouting. Applications open annually in January, closing by April 1st, promoting community engagement and educational advancement.

The Intervention Research to Improve Native American Health (R21 Clinical Trials Optional) aims to support exploratory studies focused on enhancing health outcomes within Native American populations. This initiative encourages research that addresses critical health disparities, tests new interventions, and develops culturally appropriate solutions to improve health and well-being. Applications are encouraged to include community-driven research, addressing unique sociopolitical and environmental challenges faced by these populations, ultimately aiming to reduce morbidity and mortality.

The Rotary Club of Hagerstown Sunrise Foundation Scholarship Fund provides financial assistance to graduating high school students and non-traditional learners pursuing a degree or certificate in various fields. This initiative, supported by the Community Foundation of Washington County, aims to honor local contributions and foster educational opportunities. Applicants must demonstrate commitment to community service and leadership. Scholarships open annually in January and close on April 1st, benefiting the community for generations.

This funding opportunity announcement aims to enhance health interventions for Native American populations. It supports research to develop, adapt, and test culturally informed health promotion and disease prevention strategies. The initiative addresses significant health disparities faced by these communities, emphasizing sustainable and adaptable solutions. Researchers are encouraged to build on community strengths and resilience, focusing on effective dissemination and integration of interventions. The program welcomes applications targeting diverse Native American groups, including Alaska Natives and Native Hawaiians.

The Bausch Foundation, established by Bausch Health Companies Inc., supports global charitable initiatives focused on disease prevention, improving patient outcomes, and education related to its core businesses. The Foundation also aids disaster recovery efforts and assists underserved communities. Applications for funding are accepted continuously, with quarterly reviews, ensuring timely support for impactful projects. All submissions must be unsolicited, and decisions by the Advisory Committee are final, fostering a transparent giving process.

The Samuel Hunter Agricultural Education Scholarship, offered by the Community Foundation of Washington County, MD, aims to support students graduating from WCPS high schools, especially those from Smithsburg High School. This scholarship is designed for students pursuing post-secondary education in agricultural fields, with a preference for FFA/4-H participants. With its commitment to enhancing local education, this scholarship not only honors community contributions but also promotes vital career paths in agriculture.

The Artist’s Palette Scholarship Fund, managed by the Community Foundation of Washington County, MD, supports students pursuing careers in cosmetology, aesthetics, barbering, nail technology, and massage therapy. This fund is designed to assist deserving individuals from Maryland, West Virginia, and Pennsylvania in achieving their educational goals. Scholarships are made possible by local families and organizations dedicated to enhancing community welfare and honoring significant contributions to the community. Applications open annually from January to April.

The Art Richards Scholarship Fund of Children In Need, Inc. offers scholarships to graduating clients of Children In Need, empowering them to pursue secondary education in academics or trades. Established in 1998, this fund was inspired by Art Richards' vision to uplift children living in poverty in Washington County, MD. Through local partnerships, the fund supports educational opportunities and honors community values, ensuring every child has the resources needed to thrive.

Michelle M. Vasenda Fund

Established in memory of Michelle M. Vasenda, a career nurse who lost her battle to breast cancer in 2009. It was her vision to create a scholarship to help those committed to helping others.

Amount: Varies

• $1,000-$2,000

Number of awards:

• Varies

Renewal:

• Must reapply annually by submission of a new application.

The Yass Prize & STOP Awards Initiative aims to revolutionize education by recognizing and supporting exceptional education providers focused on Sustainable, Transformational, Outstanding, and Permissionless (STOP) education. Established in 2021, the initiative awards funds to organizations serving Pre-K to 12th grade students across the United States, fostering impactful partnerships and innovative practices. With a commitment to transforming educational experiences, the initiative celebrates the vital work of educators in response to contemporary challenges.

Blue Meridian Partners Grant aims to transform lives of young people and families in poverty by investing in scalable strategies that enhance economic and social mobility. The organization seeks stand-alone nonprofits with a proven track record, a compelling vision, and strong leadership. With a commitment to performance-based investing, Blue Meridian provides significant capital, often exceeding $100 million, to foster impactful solutions and address pressing social challenges effectively.

The Tribal Self-Governance Planning and Negotiation Cooperative Agreements are designed to assist tribes in planning and preparing to manage healthcare services for their members through the Tribal Self Governance Program. The Indian Health Service will provide three awards under this initiative, aiming to empower tribal organizations in their efforts to enhance healthcare delivery and self-determination.

The Loren Engel Memorial FFA Scholarship, established by Margaret Engle in 2005, honors Loren Engel’s dedication to agriculture and leadership. This $300 scholarship is available for graduating high school students from Dickinson County who have served as FFA chapter officers, demonstrating commitment to agricultural education. The Community Foundation of Dickinson County aims to support local students pursuing technical or vocational education, ensuring future generations can thrive in their community.