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Best Private Grants for Nonprofits in South Carolina

Find the perfect Private grants for nonprofits in South Carolina on Instrumentl. 9,000+ Private grants for nonprofits in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,451 Results based on applied filters

NASN Research Grants

National Association of School Nurses
Association/Society
United States
US $1,000 - US $25,000
The NASN Research Grants, established by the National Association of School Nurses, aim to promote research on school nursing and the health of school-aged children. These grants support innovative projects led by school nurses who are NASN members. The program emphasizes the importance of quality school nursing practice, encouraging applications that adhere to specified guidelines and focus on future research initiatives. With a rich history of funding impactful studies, NASN continues to advance healthcare delivery in educational settings.
School Health Nursing

Midcareer Investigator Award in Patient-Oriented Research (Parent K24 - Independent Basic Experimental Studies with Humans Required) (353794)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) supports mid-career health-professional doctorates by providing protected time for patient-oriented research (POR). This grant also enables recipients to serve as research mentors for clinical residents, fellows, and junior faculty. Key deadlines for applications span from June 2024 to February 2027, ensuring ample opportunities for interested applicants to engage in impactful research and mentoring.
Health & Medicine Medical Education & Professional Training Science +1 more

Science Ambassador Scholarship

Cards Against Humanity
Corporate
United States
Up to US $20,000
The Science Ambassador Scholarship, funded by Cards Against Humanity, offers full tuition for women and non-binary students pursuing degrees in STEM fields. This scholarship is open to undergraduate students and high school seniors, regardless of U.S. citizenship, as long as they plan to attend college in the United States or its territories. Eligible applicants must major in science, technology, engineering, or math.
Engineering Mathematics Science +3 more

Research Opportunities for New and At-Risk Investigators to Promote Workforce Diversity (R01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Research Opportunities for New and At-Risk Investigators (R01 Clinical Trial Optional) program invites applications that promote workforce diversity in health-related sciences. This initiative encourages researchers from underrepresented backgrounds to propose independent research projects in alignment with NIH's mission. Important deadlines for standard and renewal applications range from February 2025 to November 2027. This effort aims to enhance diversity and inclusion within the scientific community.
Science Health & Medicine Diversity, Equity & Inclusion +1 more

Facilitating Research at Predominantly Undergraduate Institutions

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The National Science Foundation (NSF) offers funding opportunities through the Research in Undergraduate Institutions (RUI) and Research Opportunity Awards (ROA) programs. These initiatives support faculty research at predominantly undergraduate institutions, fostering professional engagement and educational integration. Eligible institutions include accredited colleges and universities that award degrees in NSF-supported fields but have limited Ph.D. production. Proposals are evaluated by NSF programs based on disciplinary relevance and funding is allocated within existing research and education programs.
Engineering Mathematics Science +2 more

Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) (353745)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Mentored Clinical Scientist Research Career Development Award (K08) aims to develop the research careers of individuals with clinical doctoral degrees. This program provides essential support and protected time for intensive, supervised research experiences in biomedical and behavioral fields, including translational research. Important deadlines for applications span from June 2024 to February 2027, accommodating various grant types, including standard and AIDS-related applications.
Medical Education & Professional Training Science Health & Medicine +1 more

Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed) (353751)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Mentored Research Scientist Development Award (K01) supports early-career scientists with up to five years of protected time for intensive research training in biomedical, behavioral, or clinical sciences. This award is tailored for those pursuing independence in research and is particularly beneficial for individuals transitioning fields or returning from a hiatus. Importantly, applicants must not lead independent clinical trials but may participate in trials overseen by mentors.
Medical Education & Professional Training Science Health & Medicine +1 more

Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required) (353749)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Mentored Research Scientist Development Award (K01) aims to support emerging scientists by providing protected time for career development in biomedical, behavioral, or clinical sciences. This award, effective for three to five years, encourages research independence and may be beneficial for those transitioning fields or returning from a hiatus due to personal circumstances. Deadlines for applications vary, with important dates set for standard, renewal, and AIDS-related submissions.
Medical Education & Professional Training Science Health & Medicine +1 more

William E. Dean III Charitable Foundation Grants

William E. Dean III Charitable Trust
Private
United States
US $5,000 - US $10,000
The William E. Dean III Charitable Foundation, established in 2009, supports 501(c)(3) organizations in the U.S. and D.C. with a focus on animal welfare, education, human services, and religious initiatives. Grants are specifically aimed at programs aiding canines and veterans transitioning to civilian life, as well as preventing animal cruelty. Organizations must wait one grant cycle before reapplying, ensuring a fair distribution of funds to various causes.
Animal Welfare - General Military & Veterans Services Education +2 more

ISF Public Interest Legal Fellowship

Islamic Scholarship Fund
Association/Society
United States
US $70,000
The ISF Public Interest Legal Fellowship empowers American Muslims by providing opportunities in public interest law. This fellowship offers a salary of $70,000, professional development workshops, and mentorship to help fellows advance their careers. Applicants must be active members of the Muslim community, have graduated from law school within the last three years, and have secured a host organization for their project proposal. This initiative aims to increase representation and influence in policy-making.
Law Social Justice / Human Rights Legal Services +1 more

EA Funds : EA Infrastructure Fund Grant

Centre For Effective Altruism Usa Inc
Private
Countries
US $10,000 - US $300,000
The EA Infrastructure Fund Grant supports projects that enhance effective altruism by improving access to talent, capital, and knowledge. With grants typically ranging from $5,000 to $200,000, it welcomes applications from individuals, nonprofits, and academic institutions worldwide. However, individuals must ensure their projects conclude by August 31, 2025. The fund aims to amplify the impact of direct charitable work and foster a community committed to effective altruism principles.
Volunteerism & Philanthropy Nonprofit Growth & Development Community Services +1 more

Art & Anne Huggler Memorial Scholarship

Marion Community Foundation
Private
United States
Unspecified amount

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

Art & Anne Huggler Memorial Scholarship

The Art & Anne Huggler Memorial Scholarship Fund supports local students pursuing a degree in education or engineering.

Art hailed from Harrisburg, Pennsylvania, graduating with a degree in electrical engineering from Penn State. He was a Navy veteran of World War II and worked for GTE for 35 years. He enjoyed travel and golf and was a licensed pilot. Anne was a teacher and homemaker. They are the parents of two, grandparents of five and great-grandparents of nine. The couple was active with St. Paul’s Lutheran Church, where Art directed Art Market Marion.

The Huggler Scholarship seeks especially to assist Marion area students with substantial financial need. It was established in 2015 by their daughter, Linda Halt.

Education - Higher Education Academic Scholarship Programs Engineering +1 more

Procter & Gamble Strategic Fund Grant

Procter & Gamble Fund
Private
American Samoa, Guam +4 more
Unspecified amount
The Procter & Gamble Strategic Fund Grant aims to enhance lives through impactful initiatives such as infant development, hygiene, and oral care. As a highly competitive fund, it supports IRS-designated 501(c)(3) organizations that provide national programs where P&G can uniquely add value. Interested applicants should carefully assess their eligibility and align with the grant's specific focus areas before applying.
Community Services Economic Services & Development Disaster Relief / Humanitarian Aid +1 more

Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Required) (355587)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) program aims to enhance diversity in research by supporting early career investigators from underrepresented backgrounds. This initiative offers a K99/R00 career transition award for postdoctoral scholars and a UE5 cooperative agreement that provides mentorship and professional development. The program's goal is to ensure successful transitions into independent, tenure-track faculty roles in NIH mission areas, ultimately fostering a more inclusive scientific community.
Medical Education & Professional Training Science Biology +1 more

Sam Noble Foundation Grant

The Samuel Roberts Noble Foundation, Inc
Private
United States
Unspecified amount
The Sam Noble Foundation Grant aims to uphold the philanthropic legacy of Lloyd Noble by funding agricultural research and supporting charitable initiatives that enhance health, education, and community strength. Geared towards 501(c)(3) nonprofits in the U.S., the foundation prioritizes projects in Oklahoma and does not entertain multiyear commitments or funding for individuals or for-profit entities. The foundation seeks to address agricultural challenges while expanding educational and health services.
Agriculture Education Health & Medicine +2 more

The Neag Foundation Grant

The Neag Foundation
Private
United States
Unspecified amount
The Neag Foundation Grant aims to foster positive change in education, healthcare, and the arts. Supporting initiatives in Pennsylvania and Connecticut, the foundation focuses on enhancing educational opportunities, advancing healthcare interventions, and promoting the arts and humanities. By encouraging innovative projects that receive community support, it seeks to improve the quality of life for individuals and families. Organizations with a 501(c)(3) status are encouraged to apply for funding opportunities that align with these goals.
Health Care Access & Delivery Humanities & Social Science Education - Higher Education +1 more

ROSES 2025: D.4 Theoretical and Computational Astrophysics Networks

National Aeronautics and Space Administration (NASA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The ROSES 2025: D.4 program by NASA focuses on enhancing theoretical and computational astrophysics through collaborative networks. It aims to address grand challenges in Time Domain Multi-Messenger Astrophysics by integrating diverse expertise from various fields. Researchers from U.S. institutions are encouraged to propose innovative tools for modeling complex multi-messenger phenomena, fostering interdisciplinary collaboration across academic, national laboratory, and private sectors to prepare the next generation of scientists.
Mathematics Physics Astronomy & Astrophysics +2 more

Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required) (353792)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) aims to support mid-career health professionals in conducting patient-oriented research while mentoring clinical residents and junior faculty. This grant offers protected time for research, ensuring participants can focus on impactful studies and foster the next generation of clinical researchers. Key deadlines for applications range from June 2024 to February 2027, with specific dates for standard, renewal, and AIDS-related submissions.
Health & Medicine Medical Education & Professional Training Science +1 more

Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed) (353793)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) supports mid-career health professionals by providing protected time for patient-oriented research and mentorship to clinical residents, fellows, and junior faculty. The program aims to enhance research capabilities and promote career development in the field of patient-oriented research. Key deadlines for applications include June 12, 2024, and October 12, 2024, among others, ensuring opportunities for renewal and resubmission.
Medical Education & Professional Training Science Health & Medicine +1 more

Eastman Foundation Grants

Eastman Foundation
Corporate
Galveston County, Texas, Gregg County, Texas +10 more
Unspecified amount
The Eastman Foundation Grants promote corporate social responsibility by enhancing the quality of life through sustainable community improvement. By partnering with nonprofit organizations, the foundation focuses on economic success, social well-being, and environmental integrity. The foundation emphasizes creating diverse and inclusive communities, addressing human needs while minimizing environmental impact. Grants are available for qualified organizations that align with these goals, ensuring that funding supports initiatives that foster healthy, vibrant communities where both people and nature can thrive.
Economic Services & Development Community Services Basic Human Needs +1 more

The Ed Dwight Scholarship

National Association For The Advancement Of Colored People
Private
United States
US $2,500

The Ed Dwight Scholarship

The Ed Dwight Scholarship is one of many funding opportunities available to students through NAACP's Inspire Initiatives. We offer scholarships to outstanding and qualified students pursuing undergraduate degrees. Through the generosity of our donors, we advance efforts to ensure equity in educational opportunities that prepare students for success in school, work, and life.

The Ed Dwight Scholarship honors Ed Dwight, a trailblazer in the American space program, author, and sculptor. Ed was the first Black astronaut candidate, the first to enter the program, complete the training and fully qualified as an astronaut. At the age of 90, he finally had the opportunity to see the earth from outside the atmosphere and became the oldest person to go to space.

Scholarship amount:

  • $2,500 

This is a non-renewable scholarshipopportunity.

Engineering Education - Higher Education Science +2 more

The Genesis Mission: Transforming Science and Energy with AI

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $16,000,000
The Genesis Mission by the DOE aims to transform science and energy through AI by inviting interdisciplinary teams to tackle significant challenges in energy, environment, and nuclear sectors. With multiple deadlines for FY26 Phase I and II applications, the initiative encourages leveraging diverse scientific resources to enhance R&D workflows. Successful proposals could integrate AI advancements into the American Science Cloud, fostering innovation in critical areas like advanced manufacturing and quantum information science.
Computer Science & Engineering Artificial Intelligence (AI) Cybersecurity +1 more

Health and Extreme Weather Research Coordination and Data Center (U2C - Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Environmental Health Sciences (NIEHS) is seeking applications for research coordination and data support under the Health and Extreme Weather initiative. This funding opportunity aims to engage NIH grantees and the broader community by sharing best practices, developing training resources, and facilitating access to health and environmental data. The initiative will enhance collaboration, reduce duplication, and promote data standards to support impactful research and infrastructure activities.
Health & Medicine Atmospheric Sciences Data Science & Digital Information Systems +1 more

NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) (353762)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Pathway to Independence Award (K99/R00) program is designed to support promising postdoctoral researchers in transitioning to independent faculty positions. This initiative aims to maintain a strong cohort of talented investigators by providing independent NIH research funding during this critical phase. Key application deadlines span from June 2024 to February 2027, encouraging applications from diverse fields, including AIDS-related research.
Science Health & Medicine Diseases & Conditions +1 more

NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required) (353763)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Pathway to Independence Award (K99/R00) supports the transition of postdoctoral researchers to independent faculty positions. It aims to enhance the number of talented NIH-supported investigators by providing funding during their transition to independent research careers. Key deadlines for applications are set for various dates through 2027. This program is crucial for developing a strong cohort of new independent researchers, fostering innovation in health-related fields.
Medical Education & Professional Training Science Health & Medicine +1 more

Enhancing Student Mathematics Learning Through the Use of Tools and Technology Grant (PK-12)

National Council of Teachers of Mathematics
Association/Society
United States
Up to US $4,000
The Enhancing Student Mathematics Learning through the Use of Tools and Technology Grants, provided by the National Council of Teachers of Mathematics, aim to promote innovative technology use in teaching mathematics to Pre-K-12 students. These grants encourage proposals that focus on enhancing students' understanding of math concepts through various tools, including professional development for educators. Eligible applicants include current math teachers and full-time coaches, with a focus on impactful evaluation plans.
Teacher Development & Training Mathematics Technology Access & Digital Literacy +1 more

Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) (353746)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Clinical Scientist Research Career Development Award (K08) supports individuals with clinical doctoral degrees to pursue intensive research training. This program focuses on developing skills in biomedical and behavioral research, addressing national health-related research needs. Key deadlines for applications span from June 2024 to February 2027, with specific dates for standard, renewal, and AIDS-related grants, ensuring that qualified candidates have ample opportunity to apply and advance their research careers.
Medical Education & Professional Training Science Health & Medicine +1 more

Private Grants for Nonprofits in South Carolina Highlights

Looking for private grants for nonprofits in South Carolina?


Read more about each grant below or start your 14-day free trial to see all private grants for nonprofits in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Private Grants for Nonprofits in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Private grants for nonprofits in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Private grants for nonprofits in South Carolina over $25K in average grant size

40 Private grants for nonprofits in South Carolina over $50K in average grant size

32 Private grants for nonprofits in South Carolina supporting general operating expenses

100+ Private grants for nonprofits in South Carolina supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

500+ Grants on Instrumentl focused on Writing & Literature

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Private grants for Nonprofits in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Private Grants for Nonprofits in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Private Grants for Nonprofits in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Private Grants for Nonprofits in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Private Grants for Nonprofits in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081