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Best Private Grants for Nonprofits in South Carolina

Find the perfect Private grants for nonprofits in South Carolina on Instrumentl. 9,000+ Private grants for nonprofits in South Carolina in the United States.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,447 Results based on applied filters

Assisting Specialty Crop Exports: Low Oxygen Storage and Packaging Systems for U.S. Tree Nuts with Phytosanitary Traceability

Foreign Agricultural Service
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The Assisting Specialty Crop Exports initiative aims to enhance U.S. specialty crop market access by developing low-oxygen storage and packaging systems for tree nuts. By addressing phytosanitary requirements and pest control, the initiative supports producers in maintaining product quality while complying with international standards. This funding opportunity from the Foreign Agricultural Service encourages innovative solutions that can improve export processes and reduce reliance on costly fumigation methods, ultimately benefiting U.S. agribusiness and ensuring competitiveness in global markets.
Agricultural Crops Insect Pest Control Agricultural Pest Management +1 more

Food as Medicine Initiative Grant

National Association of Free and Charitable Clinics Inc
Private
United States
US $20,000

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

Food as Medicine Initiative

The Food as Medicine Initiative, supported by the McKesson Foundation and administered by the NAFC, aims to address food insecurity as a critical driver of health outcomes for uninsured and medically underserved patients. Research continues to demonstrate the strong connection between food insecurity and poor health, including increased risk of chronic conditions such as diabetes, hypertension, obesity, and certain cancers. Through this initiative, NAFC will provide $20,000 grants to member free and charitable clinics to implement or expand food insecurity screening and patient-centered interventions that improve access to healthy food and nutrition education as measured by the US Household Food Security Module or Hunger Vital Signs and patient education focused on food as medicine for eligible patients in order to increase the percentage of patients with improved food security scores within one year of project implementation.

Patient Care & Services Health Care Access & Delivery Community Health Education +4 more

Roy & Gloria Dinsdale Foundation Grant

Roy And Gloria Dinsdale Foundation
Private
United States
More than US $10,000
The Roy and Gloria Dinsdale Foundation, established in 2022, is dedicated to enhancing lives in rural Nebraska, Wyoming, and Colorado through grants exceeding $10,000. It supports nonprofits and government entities focused on food, shelter, healthcare, education, and the arts. The foundation prioritizes local initiatives that enrich communities and improve access to essential services, while maintaining a commitment to assisting veterans, first responders, and individuals with disabilities.
Art & Culture Education Arts / Culture Access & Participation +9 more

Scaife Family Foundation Grant

Scaife Family Foundation
Private
United States
Unspecified amount
The Scaife Family Foundation Grant has been supporting vulnerable community members for nearly 40 years, providing over $180 million in donations to non-profits. The Foundation aims to match organizations with aligned goals, focusing on women and children, addiction prevention, and animal welfare. It offers grants for general operating and program support, prioritizing impactful programs that address societal issues. Notably, the Foundation considers proposals that foster healthy relationships and promote treatment for addiction, enhancing the welfare of both humans and animals.
Children’s Health & Pediatrics Children’s Mental Health Child Welfare Services +6 more

Emerging Artist Grant

Guild of Carillonneurs in North America
Private
North America
Up to US $2,000
The Emerging Artist Grant, offered by the Guild of Carillonneurs in North America, supports the next generation of carillonneurs by providing financial assistance for education and professional development. Eligible applicants can receive up to $750 or $2,000 depending on their qualifications, which may be used for tuition, travel, and equipment. This initiative aims to foster talent in the carillon community, ensuring a vibrant future for this unique musical art form.
Music Chamber Music Classical Music

Bridgestone Americas Trust Fund: Community Impact Grants

Bridgestone Americas Trust Fund
United States
US $5,000 - US $10,000

Bridgestone Americas Trust Fund Grants

Empowering People to Move, Live, Work, and Play

Bridgestone has awarded over $60 million to nonprofit organizations in the United States since 1951, and we are committed to continuing our legacy of giving back by supporting communities around the U.S.

Bridgestone works with grantseekers that offer solutions to keep society moving forward. Strong partners offer a human-centered approach to societal challenges in one or more of the following areas of focus: 

In addition to our three areas of focus, we will consider applications from organizations that have hosted volunteer or community engagement events with Bridgestone volunteers and organizations that have received funding in previous years. 

Health & Medicine Environmental Conservation Mammalian Conservation +5 more

John C. Bock Foundation Grants

John C Bock Foundation
Private
United States
Unspecified amount
The John C. Bock Foundation supports the preservation and enhancement of natural land areas, particularly those near Lake Mendota, Wisconsin. It aims to educate builders and developers on the importance of conserving mature woodlands and old-growth forests. The Foundation funds educational activities and research while supporting qualified conservation organizations committed to protecting these valuable landscapes. Its mission is centered on public education and the custodianship of natural resources.
Forestry Environmental Conservation Habitat & Ecosystem Restoration

Robert E & Evelyn McKee Foundation Grant

Robert E & Evelyn McKee Foundation
Private
United States
Unspecified amount
The Robert E & Evelyn McKee Foundation Grant focuses on charitable purposes, primarily supporting organizations that qualify under 501(c)(3) of the IRS Code. It awards funds in various areas including civic, cultural, education, healthcare, and youth activities. Eligible recipients are local charities and certain selected colleges for scholarships. However, the foundation does not fund other foundations, organizations outside the U.S., or individual financial aid. Awards are guided by IRS minimum requirements.
Civic Affairs Episcopalism Hospital Care +9 more

Edison Scholars Program

Edison International
Corporate
United States
US $50,000
The Edison Scholars Program, sponsored by Edison International, offers $12,500 annually to thirty high school seniors pursuing degrees in STEM fields at accredited U.S. colleges. This renewable scholarship supports students who demonstrate financial need and reside in Southern California Edison’s service territory. Scholars also gain access to a paid summer internship after their first year. Eligible majors include engineering, mathematics, and computer sciences, fostering the next generation of innovators and leaders.
STEM / STEAM Education Renewable/Sustainable Energy Chemistry +10 more

Institutional Challenge Grant

William T Grant Foundation Inc
Private
United States
US $650,000
The Institutional Challenge Grant aims to foster collaborative research by requiring institutions to adapt their policies and enhance capacities for meaningful partnerships. It encourages applications from diverse leadership teams in youth-serving areas, focusing on addressing inequalities in youth outcomes. The grant outlines four key goals: strengthening partnerships, pursuing a joint research agenda, facilitating institutional change, and enhancing collaborative capacities for producing actionable research evidence.
Juvenile Justice Child Welfare Services Children’s Mental Health +4 more

NAILBA Charitable Foundation Grant

Nailba Charitable Foundation
Private
United States
Unspecified amount
The NAILBA Charitable Foundation Grant aims to support small, well-managed U.S. charities that assist those in need, particularly children. Grants are available to organizations with backing from a NAILBA member and that meet specific criteria, such as nonsectarian operation and appropriate fiscal accountability. Since its inception in 2002, the foundation has invested in community transformation by funding initiatives that directly engage in beneficial services, thereby enhancing the welfare of underprivileged groups.
Basic Human Needs Youth Services Poverty Alleviation & Services +7 more

AHRQ Small Health Services Research Grant Program (R03)

US Department of Health and Human Services: Agency for Healthcare Research and Quality (AHRQ)
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The AHRQ Small Health Services Research Grant Program (R03) invites applications for health services research focused on enhancing healthcare quality and patient safety. This funding opportunity supports diverse research settings, including hospitals and home healthcare. Projects may involve collaboration with various stakeholders such as patients, clinicians, and policymakers. By addressing AHRQ research priorities, this initiative aims to improve healthcare delivery and practice while promoting effective partnerships across the healthcare spectrum.
Health & Medicine Health Care Access & Delivery Primary Health Care +4 more

The Fred C. Gloeckner Foundation Research Fund

American Floral Endowment (AFE)
Private
United States
Unspecified amount
The Fred C. Gloeckner Foundation Research Fund, established in 2024 through a partnership with the American Floral Endowment (AFE), is dedicated to advancing floriculture research and education. With over 120 years of combined funding experience, it supports innovative projects across various fields related to floriculture. Grants are available for substantial research initiatives at U.S. universities and institutions, focusing on outcomes beneficial to the public, while ensuring projects are reviewed annually for renewal.
Horticulture & Gardening Agricultural Economics Agricultural Education +4 more

AHRQ Health Services Research Projects (R01) (352218)

US Department of Health and Human Services: Agency for Healthcare Research and Quality (AHRQ)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The AHRQ Health Services Research Projects (R01) aims to fund innovative health services research that aligns with AHRQ's priorities, such as enhancing healthcare quality and safety. This initiative encourages applications from various healthcare settings including hospitals and home care, promoting collaboration among diverse stakeholders like patients and policymakers. By addressing key areas of healthcare delivery improvement, this funding opportunity seeks to foster advancements in patient care and overall health system performance.
Health & Medicine Patient Care & Services Health Care Access & Delivery +4 more

AHRQ Health Services Research Demonstration and Dissemination Grants (R18) (352227)

US Department of Health and Human Services: Agency for Healthcare Research and Quality (AHRQ)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The AHRQ Health Services Research Demonstration and Dissemination Grants (R18) aim to support innovative health services research that addresses priorities in quality, safety, and effective healthcare delivery. These grants encourage collaboration among various stakeholders, including patients and policymakers, to enhance healthcare practices across diverse settings. Applications are due by 5:00 PM local time of the applicant organization. This initiative fosters improvements in healthcare outcomes and delivery systems.
Health & Medicine Health Care Access & Delivery Primary Health Care +4 more

McInnes Charitable Trust Grant

Sally Brown McInnes and John "Mac" McInnes Charitable Trust
Private
United States
US $20,000 - US $35,000
The McInnes Charitable Trust, founded by Sally and John McInnes, aims to support organizations in Colorado focused on animal welfare, children's health, education, and empowerment. The Trust prioritizes funding for exempt organizations under Section 501(c)(3) with a proven track record. It typically does not fund capital improvements or multi-year commitments. By fostering a spirit of generosity, the Trust honors the McInnes family's legacy and commitment to various charitable causes.
Education - Preschool / Early Learning Children With Disabilities Youth Services +6 more

Arkansas Audubon Society Trust Grants

Arkansas Audubon Society Inc.
Private
United States
US $500 - US $1,200
The Arkansas Audubon Society Trust Grants support conservation, research, and education projects focused on Arkansas bird species and their habitats. Established in 1972, the trust offers grants ranging from $100 to $1200, prioritizing projects within the state but considering broader initiatives as well. Eligible applicants include individuals, students, educators, and nonprofits. Proposals are accepted biannually, with meetings held to discuss funding decisions, fostering a community dedicated to avian conservation.
Ornithology Ornithological Conservation Environmental Conservation +2 more

Humanity United Grant

Humanity United
Private
Asia, Colombia +3 more
Approximately US $150,000
The Humanity United Grant focuses on addressing human exploitation and violent conflict through a strategic approach. It emphasizes support for registered charities and initiatives globally, particularly in regions like Asia-Pacific and South Sudan. The grant fosters collaboration among partners to promote human dignity, racial justice, and peacebuilding. Interested organizations are encouraged to align their proposals with the outlined themes and engage with the funder for potential support.
Public Policy Journalism International / Foreign Affairs +5 more

St. Mary's Bank Charitable Foundation- Donation and Sponsorship

St. Marys Bank Charitable Foundation
Private
United States
US $250 - US $2,500
St. Mary's Bank Charitable Foundation Community Support Grants aim to enhance community welfare by providing financial support to nonprofit organizations. With a commitment to 'people helping people' since 1908, the foundation focuses on areas like youth programming, homelessness, and civic support. In 2023 alone, they donated over $200,000 to 190 organizations, reflecting their dedication to improving lives in New Hampshire. They prioritize funding for nonprofits within their service areas, ensuring impactful contributions to local communities.
Basic Human Needs Military & Veterans Services Homelessness Services +7 more

Minority Dissertation Fellowship Program in Education Research

American Educational Research Association
Private
United States
Up to US $27,000
The AERA Minority Dissertation Fellowship in Education Research aims to enhance diversity in education research by supporting doctoral dissertation projects from advanced graduate students belonging to historically underrepresented racial and ethnic groups. By providing a $25,000 stipend and opportunities for mentorship, the program encourages high-quality research across various educational topics, including STEM education and achievement gaps. This fellowship not only aids in academic development but also fosters the competitiveness of minority scholars in higher education.
Education - Higher Education Education System Policy & Reform Economics +10 more

Arctic Research Opportunities (349724)

National Science Foundation (NSF)
Federal Government
Canada, Greenland +1 more
Up to US $330,000
The National Science Foundation (NSF) seeks proposals for Arctic research to enhance understanding of the rapidly changing Arctic environment and its social systems. This initiative encourages innovative research that connects the Arctic region with lower latitudes, aiming to improve projections of future changes. Collaborations with federal and international partners are encouraged for co-reviewing proposals. Proposals that extend beyond the Arctic must clearly articulate their relevance to Arctic knowledge advancement.
Oceanography Hydrology Environment +7 more

Change Happens Foundation Grant

Change Happens Foundation A Delaware Nonprofit Corporation
Private
United States
Unspecified amount
The Change Happens Foundation Grant focuses on supporting charitable initiatives aligned with environmental science, education, and human services. With a commitment to diversity, equity, and inclusion, the foundation prioritizes funding for organizations holding 501(c)(3) status, while advocating for innovative solutions to pressing global challenges. Grants aim to foster systemic change, empower underrepresented communities, and bridge gaps in access to nutrition and healthcare. The foundation operates nationally and internationally, seeking to create significant impact through strategic investments.
Education - Preschool / Early Learning Science Engineering +9 more

NRF Foundation: Licensing International Scholarship

NRF Foundation
Private
United States
US $5,000
The NRF Foundation x Licensing International Scholarship offers a $5,000 tuition scholarship and a trip to New York City for undergraduate students pursuing careers in brand licensing. Eligible candidates must be enrolled full-time at an accredited U.S. college, have a minimum GPA of 3.0, and be available to attend the NRF Foundation Student Program in January 2026. Bilingual students are especially encouraged to apply, enhancing diversity in the retail industry.
Education - Higher Education Academic Scholarship Programs Business Education +5 more

Elizabeth M. Pfriem Foundation Grant

Elizabeth M Pfriem Foundation
Private
United States
Unspecified amount
The Elizabeth M. Pfriem Foundation, established in 2015 in Rye Brook, New York, is committed to enhancing the human condition through grants to 501(c)(3) public charities. Focusing primarily on the greater Bridgeport, Connecticut area, it supports initiatives in education, healthcare, food security, and housing. The foundation prioritizes organizations demonstrating fiscal responsibility and innovative programs with significant impact potential, ensuring sustainable support for vulnerable populations, especially children and families in need.
Basic Human Needs Poverty Alleviation & Services Equitable & Affordable Housing +4 more

Skilled Trades Scholarship

Community Foundation of Monroe County
Private
United States
US $1,000

About Us

Making a Difference, Together

The Community Foundation of Monroe County (CFMC) builds a thriving, inclusive community through the power of philanthropy. By connecting generous donors with local causes, we help ensure Monroe County remains a place where everyone can thrive. Since our founding, we’ve been a trusted steward of community resources, fostering impactful collaborations and sustainable solutions to address challenges in education, health, poverty, and community development.

Skilled Trades Scholarship

The Greater Milan Area Community Fund is proud to support students pursuing skilled trades and hands-on career pathways that build practical skills, open doors to stable employment, and strengthen our local community.

Scholarship awards are typically paid directly to the accredited trade program or educational institution and are generally non-taxable.

Applications are evaluated two times each year for awarding in the six months after application and selection.

Vocational & Trade Education Workforce Preparation & Job Readiness Career / College Preparation +6 more

Just One More Grant

Just One More Foundation
Private
United States
US $500 - US $10,000
Just One More Grant aims to transform lives by providing financial support to individuals and nonprofit organizations in the U.S. who are overcoming challenges like mental health issues, drug misuse, and educational barriers. The foundation encourages applications from those committed to personal growth and community support. Though current grants are paused for nonprofits, interested individuals with actionable plans are invited to apply. More information and past winners can be found on their website.
Mental Health & Psychiatric Diseases Education Health & Medicine +3 more

Sensata Foundation Grant

Sensata Technologies Foundation Inc
Private
United States
US $5,000 - US $25,000
The Sensata Foundation, established in 2017, is a 501(c)(3) nonprofit supporting community development and STEM education across the U.S. With a focus on improving access to STEM resources and empowering youth, the Foundation partners with nonprofits to address food insecurity, homelessness, and environmental sustainability. By fostering community partnerships and providing financial support, Sensata Foundation aims to inspire future leaders and enhance the quality of life for all, particularly in underserved areas.
Homelessness Services Environment Food Security +3 more

Private Grants for Nonprofits in South Carolina Highlights

Looking for private grants for nonprofits in South Carolina?


Read more about each grant below or start your 14-day free trial to see all private grants for nonprofits in South Carolina recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Private Grants for Nonprofits in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Private grants for nonprofits in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

53 Private grants for nonprofits in South Carolina over $25K in average grant size

40 Private grants for nonprofits in South Carolina over $50K in average grant size

32 Private grants for nonprofits in South Carolina supporting general operating expenses

100+ Private grants for nonprofits in South Carolina supporting programs / projects

2,000+ Grants on Instrumentl focused on Art & Culture

500+ Grants on Instrumentl focused on Writing & Literature

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Private grants for Nonprofits in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
25.2%
Q3
24.8%
Q4
21.1%

Typical Funding Amounts

What's the typical grant amount funded for Private Grants for Nonprofits in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$535,356 $535.4 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Private Grants for Nonprofits in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Private Grants for Nonprofits in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Private Grants for Nonprofits in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081