Best Private Grants for Nonprofits in South Carolina

Clinical Research Training Scholarship in Autoimmune Neurology

This award recognizes the vital importance of rigorous clinical and translational research and aims to inspire and support early-career investigators pursuing clinical studies in autoimmune neurology — specifically immune-mediated diseases of the nervous system other than multiple sclerosis.

The scope of this award encompasses research on autoimmune neurologic disorders, including neural antibody-associated diseases of the nervous system, autoimmune encephalitis, immune-mediated epilepsy, autoimmune movement disorders, inflammatory myelopathies, NMOSD, MOGAD, paraneoplastic neurological syndromes, neurological complications of cancer immunotherapies, and inborn errors of immunity/autoinflammatory syndromes affecting the nervous system.

This award will consist of a commitment of $65,000 per year for two years, plus a $10,000 per year stipend to support education and research-related costs for a total of $150,000. Supplementation of the award with other grants is permissible, but to be eligible to apply for this award, the other grant source(s) cannot exceed $75,000 annually.

The Healthy Tomorrows Partnership for Children Program (HTPCP) aims to enhance access to essential preventive clinical and public health services for children through community-driven initiatives. Funded by the US HHS: Health Resources & Services Administration (HRSA), this program focuses on empowering local communities to implement effective strategies that improve children's health outcomes and promote overall well-being. Projects funded under this initiative will play a vital role in ensuring healthier futures for children.

The National Science Foundation's Engineering Directorate (NSF ENG) promotes groundbreaking research in chemical, bioengineering, energy, and transport systems. Key programs include Chemical Process Systems, Engineering Biological and Biomedical Systems, Energy, Water, and Resource Engineering, and Transport Phenomena. NSF ENG seeks innovative, transformative proposals that push the boundaries of foundational research, regardless of immediate commercial applications, and emphasizes diverse funding opportunities based on availability.

The DoW Rare Cancers Concept Award for FY26 promotes groundbreaking ideas in rare cancer research. This award encourages innovative applications that explore novel courses of investigation without requiring preliminary data. Unique to this program is the prohibition against mentioning the Principal Investigator or collaborators in the proposal materials, ensuring an unbiased review process. This funding opportunity aims to advance scientific discovery in the rare cancer domain.

Learning from Abroad to Reimagine Health Knowledge Systems for Equity and Wellbeing Grant

The Robert Wood Johnson Foundation (RWJF) is committed to dismantling structural racism and eliminating barriers to health equity by working alongside communities, practitioners, and institutions. One way we support this mission is by investing in the knowledge of historically marginalized communities and deepening the relationships that build community power, evidence, and systems of change. Another way we do this is by looking beyond the U.S. borders. The Global Ideas for U.S. Solutions team looks abroad for ideas to improve health equity, justice, and wellbeing in the U.S.  

This funding opportunity invites organizations to learn and produce solutions to build a more inclusive and equitable health knowledge system, inspired by other countries that have faced or are currently facing similar health equity challenges. It allows organizations to learn from efforts outside of the U.S. to reimagine and rebuild the health knowledge system in ways that can withstand systemic threats while advancing health equity and wellbeing for the future. Among many other characteristics yet to be identified, our learnings to date suggest that the following contribute to this reimagined version of the health knowledge system:  

• The experience of people most affected by health inequities is centered in the generation of data and evidence and in policymaking;
• Health is more than the absence of disease. It is about individual and collective healing and wellbeing;
• Mis- and disinformation are eliminated and public trust in science and evidence is restored;
• History, culture, and language are preserved and protected, and ecological and biomedical sciences are braided with Indigenous, traditional, holistic, and community frameworks; and
• Cross-sector approaches and global learning networks break down siloes and allow for more effective and equitable solutions. They leverage lessons from resistance movements and connect artists, researchers, public health, and civil society.

The purpose of this CFP is to support organizations in pursuing action-oriented projects that leverage learning from outside the U.S. to create a more durable and equitable health knowledge system in the U.S. These efforts will advance health equity, justice, and wellbeing through community-driven knowledge generation, preservation, and narrative. Together, these actions lay the foundation for a more inclusive, equitable, and resilient health knowledge system in times of crisis and beyond. 

Total Awards

Type of Award: Awards will be structured as grants and will be made to organizations, not to individuals.

• Number of Awards: Up to 15 awards will be funded.  
• Amount of Award: Awards will be up to $500,000 each. Please request only what is necessary to allow us to fund as many recipients as possible. We expect larger awards to correspond with more distributed funding (e.g., multiple people’s salaries or multiple activities). See more information on RWJF budget categories and allowable costs here.  
• Award Duration: Awards will be up to 36 months.  

Dave Dupont Memorial Scholarship

The family remembers Dave as a very kind hearted, loving husband, father, and friend. He and his wife Sandi were married 35 years, and had 2 children Kyle and Danielle DuPont.

Dave loved to give back to his community, and attend as many fundraisers as he could. Dave would be proud to be able to give back to the kids in his community.

Project Lead the Way inc.

School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world. 

PLTW Launch (PreK-5)

Young learners are naturally wired for discovery. PLTW Launch is designed with activities that let them see what they can be and build skills to discover what they can do. Students are immersed in hands-on activities, projects, and problems that build upon each other and relate to the real world. They experience integrated learning that blends computer science, engineering, biomedical science, and more. Throughout the modules, even the youngest learners apply their math and English Language Arts (ELA) skills, learn science to standards, and adopt skills that are foundational across disciplines.

PLTW Launch - Program Expansion (3M)

3M forms lasting partnerships with communities and provides resources to help them succeed and grow – ensuring a more interconnected and thriving world. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities
• Enhancing the quality of STEM teaching
• Providing professional development opportunities for students

3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM.

Seattle Foundation

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Nora Stone Smith Scholarship

The Nora Stone Smith Scholarship honors and gives financial support to deserving immigrant high school seniors and students who have graduated in the past year and have participated in an ESL/ELL program at some point in their lives. This scholarship is available for all ESL/ELL students, regardless of their citizenship status. Undocumented students are encouraged to apply. This scholarship is $2,000 and renewable for 2 or 4 years.

The Chemical Process Systems (CPS) program, funded by the National Science Foundation (NSF), focuses on advancing research in chemical and biochemical processes to enhance efficiency, sustainability, and resilience. It aims to support innovative technologies across various sectors, including manufacturing and energy. By exploring areas such as catalysis, electrochemical systems, and advanced separations, CPS seeks to improve processes and materials in critical domains like bioprocessing and nuclear fuel cycles, while fostering partnerships to drive discovery and innovation.

Real World Evidence on clinical outcomes with Aztreonam-Avibactam (ATM-AVI)

This RFP invites research proposals aimed at assessing clinical outcomes associated with the use of Aztreonam-Avibactam (ATM-AVI) in real world clinical settings.

In scope are adult patients with suspected or documented infections due to aerobic gram negative organisms. Eg. CRE-MBL, Stenotrophomonas maltophilia, treated with ATM-AVI.

Geographic Scope

Countries where ATM-AVI is available (ex-US) and used in clinical practice at the time of RFP release, including but not limited to parts of EU, the United Kingdom, the Middle East, and selected Asia-Pacific markets. Proposals from institutions already participating in Pfizer-sponsored or funded, overlapping ATM-AVI RWE study may be considered out of scope. Proposals involving studies on patients that have received ATM-AVI via pre-approval or pre-launch expanded access routes may be considered out of scope

Project Types and Area of Interest

Potential applicants are requested to submit research proposals to study the below outcomes following treatment with ATM-AVI for adult patients with suspected or documented infections with aerobic gram negative organisms e.g. CRE-MBL, S. maltophilia.

• Clinical effectiveness with ATM-AVI
• Safety outcomes with ATM-AVI
• Microbiological outcomes with ATM-AVI
• Health Economic outcomes with ATM-AVI (in addition to any of the above)

Proposals may include data from special populations such as – immunocompromised (solid organ transplant or haemato-oncological patients)

Funding Range and Project Length

• Individual projects requesting up to $50,000 USD will be considered. The total budget for this RFP is $ 250,000 USD
• Maximum project length is 12 months

The DoW Rare Cancers Idea Development Award promotes innovative research ideas for rare cancers, encouraging applicants to provide preliminary data and exploratory aims. This funding opportunity, offered by the US DOD: U.S. Army Medical Command, seeks projects with the potential for high-impact findings that can significantly benefit the patient community. It aims to foster new avenues of investigation and support discovery-driven research in the field of rare cancers.

Marshfield Area Community Foundation Scholarships

The mission of the Marshfield Area Community Foundation is “Connecting people who care with causes that matter to enrich the quality of life in the Marshfield area”. Education is a valuable tool and a cause that matters to all of us. Through assisting students with financial support to receive an education, not only do students and the families of those students benefit, but also our community benefits, which further allows us to achieve our mission of enriching the quality of life in the Marshfield area.

Geographical Area

The official geographic service area of Marshfield Area Community Foundation, Inc., beginning to our west and traveling clockwise, includes the following communities in addition to Marshfield (It also includes towns and rural areas between these communities.): Chili, Granton, Neillsville, Loyal, Greenwood, Withee, Owen, Spencer, Unity, Colby, Curtiss, Pittsville, Abbotsford, Dorchester, Stetsonville, Medford, Stratford, Rozellville, Hewitt, Auburndale, Blenker, Milladore, Sherry, Arpin.

Norbert H. and Joan LaSee Scholarship

This scholarship is for graduating seniors at Marshfield, Columbus, Spencer, or Stratford High School attending an accredited college, university, or tech school intending to study a career in the trades. Student financial need must be considered. Renewable for 2 additional years.

The FY26 Neurofibromatosis Research Program's Exploration-Hypothesis Development Award encourages innovative, high-risk research concepts in neurofibromatosis (NF). This award aims to support groundbreaking studies that will pave the way for future scientific inquiries. Proposals should present a well-defined, testable hypothesis grounded in sound scientific rationale. While preliminary data is encouraged, it is not a prerequisite for submission, allowing researchers to explore novel paradigms and perspectives in NF research.

Edward E. Ford Foundation

The Edward E. Ford Foundation seeks to improve secondary education by supporting U.S. independent schools and encouraging promising practices. 

• We make Traditional Grants to eligible schools and Associations to help them grow and develop in pursuit of their own missions.
• We make Educational Leadership Grants to eligible schools or groups of schools that consist of larger dollar awards to fewer recipients.
• We encourage collaboration with others in both grant cycles.
• Occasionally, we may make larger, multi-­year Collaborative Innovation Grants in support of projects that have the potential to influence secondary education more broadly and positively affect our democratic society.
• Beyond grant-making, we share what we learn, sponsor strategic meetings, and work with others to identify and respond to the most pressing challenges facing the field of secondary education.

Traditional Grant for Associations

These grants are made in response to requests that can range from $25,000 to $100,000 and that must be matched by additional funds raised by the association at least 1:1.

Associations seeking placement on a Traditional Grant Agenda should be prepared to specify the anticipated dollar value of their proposal when they request placement. This can be months in advance of the date the final version of the proposal will be due, depending on the length of the queue. 

Traditional Grants are awarded based on the quality of the proposal and other considerations in terms of the association’s operation, but it does not identify certain areas of independent school work as favored. That is, you can seek guidance as to what sort of proposals have been funded in the past but association should identify their own greatest institutional need that they think the Foundation can help address.

Step-by-Step Process

• Request Agenda Placement — Please fill out the Agenda Placement form to tell the Foundation a bit more about your association and to help us determine if it is eligible for EE Ford funding.

• Agenda Placement Phone Call — If your association is eligible for Agenda Placement, we will schedule a phone call between your association’s Executive Director and the Executive Director of the EE Ford Foundation. This phone call will serve as an informal introduction and it will determine if Agenda placement is right for your association. No proposal can be considered from associations that have not reserved a place on an upcoming Agenda. If your association is placed on an Agenda, you will receive an Agenda Placement Confirmation email with further instruction.

• Executive Director Meeting — Schedule a 2-3 hour meeting between your association’s Executive Director and our foundation’s Executive Director to be held in our Brooklyn office. The Preliminary Materials will be due one week prior to this meeting (see “Preliminary Materials” under "Required Materials"). 

• Final Submission — Deadline for submission of final materials is January 30 for the April Agenda or April 1 for the June Agenda. When the Board makes its decision about a proposal, the Executive Director communicates this decision within days.

Dr. Sonny Rush Memorial Scholarship

Dr. Sonny Rush was a pioneering orthopedic surgeon and a kind friend to all his patients. He encouraged all students interested in healthcare to pursue their passion in the medical field. This scholarship was established by his family in his memory and is designed to help jumpstart a career in the healthcare field. 

Amount

• 1500

The Clinical and Translational Science Awards (CTSA) Program aims to expedite the integration of scientific discoveries into effective health interventions. By providing essential infrastructure and support to academic medical centers, the program fosters innovative research approaches that enhance translational science. The Collaborative and Innovative Acceleration Award under this initiative seeks to promote partnerships that accelerate the development of new treatments, ultimately improving health outcomes for diverse populations.

Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County. We use distributions from the more than 500 charitable funds — created by generous, local donors — to award more than $2.5 million in grants and scholarships each year to many of the humanitarian, educational and cultural organizations in this remarkable community we call home.

Marion Community Foundation is the area’s leading philanthropic organization, providing charitable donors the opportunity to easily create endowment funds to benefit and support our community through grants and scholarships. We serve communities throughout Marion County through philanthropy, leadership, and civic engagement.

John T. & Lois Schmidt Scholarship

The John T. & Lois Schmidt Scholarship Fund was created in 2017 to support seniors and graduates of Marion County high schools who are also members of the U.S. Armed Forces, veterans, or children or grandchildren of those on active duty or veterans. The Schmidt Fund favors applicants from Elgin High School and those with GPAs of 2.5 or better.

The Schmidt Scholarship honors John and his military service. John served in the U.S. Army during World War II, from January 1943 to January 1946 and was stationed in several overseas and exotic locales, including New Guinea, Netherland East Indies, Morotai, and Mindanao in the Philippine Islands. At the end of his service, he received an honorable discharge as a staff sergeant and had earned the Bronze Star for valor and the Bronze Arrowhead—awarded to those present on D-Day on the beaches of Normandy, France.

Prior to his military career, John graduated from Agosta High School (1941) and shortly after his service, married Lois (Kraner) in 1948. He was employed by Marion Power Shovel, Marion Industries, and retired after 29 years with Whirlpool. He was a member of the Marion County Farm Bureau, Disabled American Veterans, and VFW Post 7201. John passed in 2009 at the age of 86.

The Robert Wood Johnson Foundation (RWJF) is committed to transforming health in our lifetime and to paving the way to a future where health is no longer a privilege, but a right. To achieve that vision, RWJF supports health equity research that “increases opportunities for everyone to live the healthiest life possible, no matter who we are, where we live, or how much money we make.” Achieving health equity requires identifying solutions to the historical and contemporary root causes of inequities.

From Insight to Action: Health Equity Research that Meets This Moment

Purpose

The current challenging political environment underscores the value of timely, credible research that is grounded in real‑world conditions—the type of research that has propelled the progress toward health equity our society has made. That is why RWJF is launching this CFP as part of a new research funding program, Health Equity Research for Action (HERA). HERA will support community-rooted, action-oriented health equity research that reflects lived realities and responds to immediate and long-term needs. The research will help maintain access to evidence, support accountability, and inform efforts to build more equitable systems. HERA is being developed and will be administered by three national coordinating centers (NCCs) based at the Charles R. Drew University of Medicine and Science, Michigan State University College of Human Medicine, and the Morehouse School of Medicine.

RWJF and the NCCs are interested in research that identifies the root causes of structural discrimination, challenges harmful narratives that undermine individual and community health and wellbeing, and disrupts growing mis- and disinformation. While HERA is still in its early stages, we are hoping this first CFP will sustain and advance health equity research during this critical time, while generating insights that can help shape HERA’s future funding priorities and strategies. Proposals submitted under this first CFP must include research that is conducted in equitable community partnership; focuses on at least one of RWJF’s seven Prioritized Systems; informs systems change; and leads to actionable solutions.

Jacquie Porter Scholarship for Aspiring Early Childhood Teachers in Austin ISD

Aspirations of becoming an early childhood educator.

Awards

• (1) $5,000.00

Central Alabama Community Foundation

Established in 1987 by community leaders, the Central Alabama Community Foundation serves the River Region counties of Lowndes, Macon, and Montgomery. CACF was created to provide a permanent charitable resource dedicated to strengthening nonprofits and meeting local needs in the Montgomery area.

Through a variety of funds, CACF supports projects and programs in education, health, human services, cultural arts, recreation, historic preservation, and other civic concerns.

Every year, CACF awards grants to nonprofit projects and programs providing services in Lee, Macon, and Montgomery counties.

National Village Ladies Club Scholarship

The National Village Ladies Club Scholarship benefits female graduating high school seniors of Opelika high schools who have demonstrated leadership and community service. Eligible applicants must have a minimum 3.2 GPA and plan to attend two-year or four-year college, university, or trade school.

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

Timothy Ryan Memorial Scholarship

The Timothy Ryan Memorial Scholarship Fund provides scholarships to students who exemplify characteristics exhibited by Timothy during his brief life: loving, caring, generous, family-oriented, genuine, sincere, and humorous.

Central Alabama Community Foundation

Established in 1987 by community leaders, the Central Alabama Community Foundation serves the River Region counties of Lowndes, Macon, and Montgomery. CACF was created to provide a permanent charitable resource dedicated to strengthening nonprofits and meeting local needs in the Montgomery area.

Through a variety of funds, CACF supports projects and programs in education, health, human services, cultural arts, recreation, historic preservation, and other civic concerns.

Every year, CACF awards grants to nonprofit projects and programs providing services in Lee, Macon, and Montgomery counties.

The Hawkins Educational Foundation Scholarship

The Hawkins Educational Foundation Scholarship assists students who plan to continue their education in college or vocational school programs. Applicants must be a high school senior residing in Baldwin County for at least one (1) year prior to the application deadline date. Students must have a minimum cumulative GPA of 2.0 and plan to enroll in full-time study at an accredited two-year or four-year college, university, or vocational-technical school for the entire upcoming academic year. Awards are renewable up to three years or until a bachelor’s degree is earned, whichever occurs first, and are based on satisfactory academic performance and fulltime enrollment. Awards are for undergraduate study only.

New England Foundation For The Arts

Our work at NEFA is simple: to cultivate and promote the arts in New England and beyond. Our programs support artists across many forms of expression and many geographies, connecting them with collaborators and communities, fueling creative exchange and public discourse, and strengthening the arts and culture ecosystem.

Each program and project brought to life at NEFA builds a stronger and more dynamic infrastructure for the arts. Through grants, convenings, and online tools, NEFA continues an almost 50 year history of pioneering partnerships and programs supporting the arts.

Public Art Learning Fund

The Public Art Learning Fund aims to strengthen the field of public art in New England by providing professional development support directly to artists.

The Public Art Learning Fund provides grants to support professional development opportunities for New England artists to strengthen their public art practices. Through the Public Art Learning Fund, NEFA intends to foster the continued development of more equitable, inclusive, and vibrant public spaces and public life throughout New England.

Artists may utilize the Public Art Learning Fund to: pursue a specific professional development opportunity to strengthen their own public art practice in New England and beyond. Examples may include but are not limited to attending a conference, workshop, training, or discussion related to building creative or administrative skills related to their public art practice. 

Program Values & Goals

NEFA’s Public Art programs acknowledge the necessity of addressing the intersectionality of spatial justice and racial justice in cultivating a more vibrant and equitable public art ecosystem.  

The Public Art Learning Fund aims to strengthen the public art field in the region by supporting artists in further developing the skills, resources, and connections they need to build a more vibrant and equitable community of practice in the region. Learning in partnership with grantees, NEFA strives to learn how we may be able to better support a more equitable and sustainable public art ecosystem throughout the region. 

Funding Priorities

Public Art Learning Fund equips artists with skills, resources, and connections to strengthen public art practices that contribute to more equitable, inclusive, and vibrant public spaces and public life throughout New England. 

The Public Art Learning Fund gives priority to timely opportunities that are: 

• Specifically expanding an artist’s public art practice. NEFA will look for clarity on desired learnings and application to artist’s public art practice.
• Equitably contributing to more just and inclusive public artmaking in the region. Artists at various stages in their public artmaking practice from urban, suburban, and rural communities across all six states in New England are welcome to apply.

NEFA values diverse cultural and artistic expressions as essential to more equitable and vibrant public spaces and recognizes that some artists may experience barriers to accessing professional development opportunities due to race, gender, disability, sexual orientation, class, age, and geography. The Public Art Learning Fund intends to prioritize equity in funding opportunities.

The Learning Tree Scholarship, established by The Learning Tree, Inc. through the Central Alabama Community Foundation, supports graduating high school seniors from select counties with a minimum ACT score of 20. This renewable scholarship offers up to $2,000 annually for students pursuing degrees in education, healthcare, and related fields. The foundation, active since 1987, aims to enhance local nonprofit initiatives and educational opportunities in the River Region, serving counties including Lowndes, Macon, and Montgomery.

LRPenn.com is home to the novels, plays, and screenplays of LR Penn. His books specializes in Thrillers, Dramatic Comedies, and Film Noir. Thanks to the generous support of our sponsors, grants may be available to nonprofit theater companies in the United States with 501(c)(3) status that are staging productions of plays written by LR Penn.  

Northern Chautauqua Community Foundation

Vision: We envision a vibrant, prosperous northern Chautauqua community, rich in opportunity today and tomorrow.

Our Mission

To realize our vision we focus on:

• strategic and responsive grant making
• encouraging local philanthropy and building permanent endowments for the future
• actively serving as a community leader and partner for the benefit and enrichment in our community.

Scholarships

Northern Chautauqua Community Foundation proudly manages over 200 individual scholarship funds,

St. Joseph School Scholarship

The St. Joseph School Scholarship is awarded to a graduating senior who resides in northern Chautauqua County, and intends to pursue a career teaching children with special needs.

The Minnesota Nurses Association Foundation (MNAF) offers scholarships to support nursing professionals and students. With a commitment to healthcare quality, MNAF empowers MNA members, their families, and veterans to pursue their educational goals. The scholarships enhance nursing practice and leadership, ensuring access to quality healthcare for all. MNAF's mission reflects a dedication to social justice and public health, promoting the welfare of nurses and the communities they serve. Applications are welcomed from eligible candidates seeking to advance their nursing careers.