Upcoming Webinar
Instrumentl Fall Launch: Your Grant Operating System Has Leveled Up.
Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best Unrestricted Grants for Nonprofits in South Carolina

Find the perfect Unrestricted grants for nonprofits in South Carolina on Instrumentl. 9,000+ Unrestricted grants for nonprofits in South Carolina in the United States.

9,000+

Available grants

$3.79B

Total funding

$5K

Median grant

9,000+ grants
$3.79B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,313 Results based on applied filters

Cooke Foundation: Undergraduate Transfer Scholarship

Jack Kent Cooke Foundation
Private
United States
Unspecified amount
The Jack Kent Cooke Foundation offers the Undergraduate Transfer Scholarship to outstanding community college students with financial need, providing up to $55,000 per year for two to three years to cover educational expenses. This selective scholarship supports students in completing their bachelor's degrees at accredited institutions. Recipients benefit from personalized advising and a robust network of Cooke Scholars. Eligible candidates must have a minimum GPA of 3.5 and demonstrate unmet financial need, ensuring accessibility to higher education.
Education - Higher Education Academic Scholarship Programs

Simeon J. Fortin Charitable Foundation Grant

Simeon J. Fortin Charitable Foundation
Private
United States
Unspecified amount
The Simeon J. Fortin Charitable Foundation, founded in 1986, champions cancer research initiatives aimed at finding a cure. It supports relevant projects and fellowships within medical and research institutions, ensuring a significant impact on health-related research. The grant review process is conducted by The Medical Foundation, in coordination with the King Trust Postdoctoral Fellowships, enhancing collaboration and funding opportunities for innovative research in oncology.
Cancer / Oncology

Community Care Grant

Banfield Foundation
Private
United States
Unspecified amount
The Community Care Grant, offered by the Banfield Foundation, supports nonprofit organizations and local/state government agencies in providing affordable veterinary care to owned pets. Since 2015, the foundation has aimed to enhance preventive care through grants and partnerships, helping pets in crisis and underserved communities across the U.S. This initiative ensures that essential veterinary services are accessible to all pet owners, fostering a better world for pets.
Veterinary Science & Services Animal Welfare - Domestic Animals & Pets

Boustany Foundation: Sport 4 Children Award

Boustany Foundation
Private
Austria, Belarus +29 more
Up to €50,000
The Boustany Foundation's Sport 4 Children Award aims to enhance children's lives through sports, fostering happiness, health, and social skills. Open to organizations globally, the award supports projects that utilize sports for children's well-being. With a funding of 50,000 Euros, it encourages innovative and inclusive initiatives that promote participation in sports, aiming to create positive behavioral changes and community engagement. The foundation believes in the transformative power of sports to build responsible and healthy adults.
Youth Services Sports & Athletics

MCSF- Undergraduate & Associate Degree Scholarship

Marine Corps Scholarship Foundation
Private
United States
US $2,500 - US $10,000
The MCSF- Undergraduate & Associate Degree Scholarship is designed to support the children of Marines and Navy Corpsmen pursuing undergraduate education. To qualify, applicants must demonstrate financial need and maintain a minimum GPA of 2.00. This scholarship can cover various educational expenses such as tuition, books, and transportation. It is an excellent opportunity for those who meet the eligibility criteria and are committed to furthering their education, while honoring the legacy of service in the Marine Corps.
Education - Higher Education Academic Scholarship Programs

Animal Food Regulatory Program Standards Implementation Development and Maintenance, with Mutual Reliance Initiatives Clinical Trials Not Allowed

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Up to US $300,000
The Animal Food Regulatory Program Standards Implementation Development and Maintenance initiative aims to enhance the national animal food safety system. This funding opportunity supports state regulatory programs in achieving and sustaining the Animal Food Regulatory Program Standards (AFRPS) within five years. By fostering collaboration with the FDA and standardizing regulatory processes, this initiative seeks to improve food safety, promote compliance, and mitigate foodborne illnesses, ultimately creating a more integrated food safety framework.
Animal Food & Drug Safety

Knights Templar Eye Foundation Career-Starter Research Grant

Knights Templar Eye Foundation Inc
Private
United States
Up to US $100,000
The Knights Templar Eye Foundation Career-Starter Research Grant provides up to $90,000 to support the early careers of researchers focused on preventing and curing blinding diseases in children. Eligible candidates must hold an M.D., Ph.D., or equivalent degree. Research areas include amblyopia, congenital cataract, glaucoma, and other hereditary eye diseases. This funding aims to foster innovative solutions in pediatric ophthalmology, ultimately contributing to better health outcomes for infants and children.
Eye Diseases & Disorders

Campership Grant

Colburn-Keenan Foundation
Private
United States
Up to US $500
The Campership Grant, offered by the Colburn-Keenan Foundation, aims to support children affected by chronic inherited bleeding disorders by providing up to $500 for camp attendance. This initiative is designed to help families send their children to specialized camps, fostering community and support. Eligible applicants include children under 18 with chronic illnesses and those whose siblings or parents are affected. The program emphasizes the importance of community engagement and aims to alleviate financial burdens for families.
Summer Camps

Camp Equipment & Capital Improvement Grant Program

Colburn-Keenan Foundation
Private
United States
Unspecified amount
The Camp Equipment & Capital Improvement Grant Program, established by the Colburn-Keenan Foundation, aims to enhance the experiences of children with chronic inherited bleeding disorders. This initiative provides funding to camps for acquiring new equipment or improving facilities, emphasizing the importance of a supportive environment for these children. Eligible camps must serve at least 25% of participants affected by such disorders, ensuring that the assistance directly impacts those in need.
Summer Camps

NCAA Graduate Student Research Grant Program

National Collegiate Athletic Association
Private
Canada, Puerto Rico +2 more
Up to US $7,500
The NCAA Graduate Student Research Grant Program offers funding up to $7,500 for graduate research focused on intercollegiate athletics and the psychosocial experiences of college student-athletes. It aims to enhance empirical research and provide financial support for high-quality projects. Eligible applicants must be enrolled in a graduate program at an NCAA member institution and engage in research during the award period. The program prioritizes studies that advance understanding in social and behavioral sciences.
Education - Higher Education Sports & Athletics

The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional) (357379)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity aims to advance research on how work impacts health disparities among U.S. populations. It invites innovative proposals that explore the interplay between occupation and health outcomes, particularly in communities experiencing health and healthcare inequalities. Deadlines for applications span from February 2025 to October 2027, encouraging timely submissions for various categories including standard and AIDS-related grants.
Health Disparities & Social Determinants of Health

No Kid Hungry Grant

Share Our Strength
Private
United States
Unspecified amount
The No Kid Hungry Grant, provided by Share Our Strength, aims to support schools and community groups in ensuring children have access to nutritious meals. Grants are allocated for essential equipment rather than food, addressing the unique needs of programs serving children. With a focus on reducing financial barriers, the initiative prioritizes funding for the School Breakfast Program and summer meals, ultimately striving for equitable access to resources that help combat childhood hunger and promote community engagement.
Food Access & Hunger

The Hearst Journalism Awards Program - Multimedia - Multimedia I – Narrative Video Storytelling

William Randolph Hearst Foundation
Private
United States
US $1,000 - US $3,000
The Hearst Journalism Awards Program, established in 1960, supports journalism education by awarding scholarships to exceptional undergraduate students. With up to $700,000 available in various competitions, including writing, photojournalism, and multimedia, it encourages participation from students in ACEJMC-accredited institutions. The program aims to foster talent and innovation in journalism, ensuring a diverse range of voices is represented in the media landscape. The Hearst Foundation continues to invest in the future of journalism through this esteemed initiative.
Media Arts Writing & Literature

Local Shelter/Agency Support Grant

Ms Molly Foundation
Private
United States
Unspecified amount
The Ms. Molly Foundation provides essential support for domestic violence victims through the Local Shelter/Agency Support Grant. Established in 1996, the foundation aims to raise awareness and assist local agencies committed to helping victims find safety and empowerment. Eligible applicants include 501(c)(3) nonprofit shelters that partner with Molly Maid franchises. By addressing the cycle of violence, the foundation strives to create healthier family environments and restore hope to those affected.
Domestic Violence

Karl A. Bickel and Madira Bickel Journalistic Scholarship Fund

Karl A Bickel Charitable Trust
Private
United States
Approximately US $40,000
The Karl A. Bickel and Madira Bickel Journalistic Scholarship Fund supports journalism education by providing grants to accredited colleges and universities with journalism programs. Established from Karl A. Bickel's Last Will and Testament, the fund aims to assist deserving students in their pursuit of journalism, ensuring they receive the necessary financial backing to succeed in their studies and future careers.
Journalism

The Hearst Journalism Awards Program - Television - Television I – Features

William Randolph Hearst Foundation
Private
United States
US $1,000 - US $3,000
The Hearst Journalism Awards Program, established in 1960, supports journalism education at the college level, offering scholarships for outstanding student work. With up to $700,000 in awards, it features various competitions in writing, photojournalism, audio, television, and multimedia. Open to undergraduate journalism majors at accredited institutions, the program encourages campus media participation. The Hearst Foundation, a philanthropic organization, has contributed over a billion dollars to education and the arts, reinforcing its commitment to nurturing future journalists.
Television

Merkin Peripheral Neuropathy and Nerve Regeneration Center: Seed Grants

Johns Hopkins
Private
United States
Up to US $150,000
The Johns Hopkins Merkin Peripheral Neuropathy and Nerve Regeneration Center offers Seed Grants for innovative research on peripheral neuropathy and nerve regeneration. These grants support high-risk, high-reward pilot projects addressing axon degeneration and Schwann cell dysfunction. Researchers may apply for funding of up to $75,000 per year for one or two years. The initiative aims to foster novel ideas and successful transitions to external funding, enhancing scientific understanding and therapeutic development.
Neurological Diseases & Disorders

AO North America: VET Preceptorships Program

Ao North America Inc
Private
United States
US $2,750
The AO North America VET Preceptorships Program offers surgical residents from the American College of Veterinary Surgeons the chance to enhance their skills in Veterinary Trauma and Orthopedics through a structured training experience. Participants can receive up to four weeks of advanced training in AO techniques at designated surgical centers, with funding available for housing and travel expenses, totaling up to $2,750. This initiative aims to foster professional development and improve patient care outcomes.
Veterinary Science & Services Orthopedics

The Hearst Journalism Awards Program - Writing - Explanatory Reporting – Team or Individual

William Randolph Hearst Foundation
Private
United States
US $1,000 - US $3,000
The Hearst Journalism Awards Program, established in 1960, supports undergraduate journalism education with up to $700,000 in annual awards. The program includes multiple competitions in writing, photojournalism, audio, television, and multimedia categories. Each participating university can submit two student entries per competition, fostering excellence in journalism. Open to journalism majors or minors, the program encourages students to engage actively in campus media. The Hearst Foundation, founded by William Randolph Hearst, has contributed significantly to education and the arts nationwide.
Writing & Literature News Media & Communications

James Madison Graduate Fellowship

James Madison Memorial Fellowship Program
Federal Government
United States
Up to US $24,000
The James Madison Graduate Fellowship supports U.S. citizens pursuing master's degrees focused on the Constitution, enhancing their constitutional knowledge for teaching. Fellows are required to teach American history, government, or civics at the secondary level for one year per funding year. Financially, the fellowship awards up to $24,000, covering tuition and fees, and must be repaid if fellowship conditions are unmet. This program ensures future educators embody constitutional principles in their teaching.
Education American History Civic Affairs

Limited Competition PCORI Funding: Implementation Awards -- Cycle 3 2026

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $2,500,000
The Implementation Awards by PCORI aim to fund projects that translate patient-centered research into real-world practices. With budgets up to $2.5 million for implementation projects lasting up to 48 months, applicants must present a clear plan for broad evidence uptake. Additionally, those proposing implementation projects need an accepted Draft Final Research Report related to their original PCORI-funded research to qualify for funding.
Patient Care & Services

Intellectual and Developmental Disabilities Topical PCORI Funding

Patient-Centered Outcomes Research Institute
Association/Society
United States
Unspecified amount
The Intellectual and Developmental Disabilities Topical PCORI Funding aims to support high-quality, patient-centered comparative clinical effectiveness research (CER) focusing on individuals with intellectual and developmental disabilities (IDD). This funding opportunity recognizes the diversity of conditions under IDD and the varying support needs among individuals. PCORI encourages the use of both person-first and identity-first language, acknowledging the preferences within the disability community, and aims to enhance the quality of healthcare delivery for these populations.
Intellectual / Developmental Disabilities

ILSG Student Research Fund

Institute on Lake Superior Geology (ILSG )
Association/Society
United States
US $500
The ILSG Student Research Fund, established by the Institute on Lake Superior Geology, aims to support student research in the Lake Superior region with annual awards totaling US$1,000. This initiative encourages the presentation of research findings at ILSG meetings, fostering academic growth and collaboration. The fund originated from a US$10,000 contribution by the Board of Directors in 2005, with ongoing financial support from annual meeting proceeds, ensuring its sustainability for future student researchers.
Geology Education - Higher Education

Bluegrass in the Schools Mini-Grants

The Ibma Foundation Inc
Private
United States
US $500
The Bluegrass in the Schools Mini-Grants program, offered by the IBMA Foundation, supports K-12 educational initiatives by funding live bluegrass music performances in schools. Grants of up to $500 are available for programs that provide a comprehensive understanding of bluegrass music, including its history, instruments, and vocal harmonies. This initiative aims to enhance student engagement with bluegrass while preserving its cultural heritage, enriching the educational landscape through live demonstrations.
Music

Animal Food Regulatory Program Standards Implementation Development and Maintenance, with Mutual Reliance Initiatives

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $10,600,000
The Animal Food Regulatory Program Standards Implementation Development and Maintenance initiative aims to foster a cohesive national animal food safety system. This funding opportunity supports state programs in implementing the Animal Feed Regulatory Program Standards (AFRPS) and encourages mutual reliance between federal and state regulatory efforts. Key outcomes include enhanced operational standards and improved integration of regulatory processes, ultimately contributing to a safer food supply and better animal health across jurisdictions.
Animal Food & Drug Safety

Animal Food Regulatory Program Alliance

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $600,000
The FDA/ORA's Cooperative Agreement Program aims to enhance the national food safety system through collaboration among federal and state agencies. Key objectives include building an integrated animal food safety system, sharing best practices, and promoting training programs for animal food safety. This initiative supports the Animal Food Regulatory Program Standards (AFRPS) and ensures ongoing improvements to meet modern regulatory needs. Eligible applicants must represent state animal food regulatory programs at a national level.
Animal Food & Drug Safety

Integrated Food Safety System Regulatory and Laboratory Training System National Coordination Center

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $1,500,000
The US Department of Health & Human Services, through the FDA, is offering a $1.5 million cooperative agreement for a non-profit to establish the Integrated Food Safety System Regulatory and Laboratory Training System National Coordination Center. This center will oversee the training system, enhancing access to high-quality regulatory and laboratory learning resources for both human and animal food safety, thereby leveraging partnerships to improve food safety training nationwide.
Food Safety

Unrestricted Grants for Nonprofits in South Carolina Highlights

Looking for unrestricted grants for nonprofits in South Carolina?


Read more about each grant below or start your 14-day free trial to see all unrestricted grants for nonprofits in South Carolina recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Unrestricted Grants for Nonprofits in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Unrestricted grants for nonprofits in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

54 Unrestricted grants for nonprofits in South Carolina over $25K in average grant size

41 Unrestricted grants for nonprofits in South Carolina over $50K in average grant size

32 Unrestricted grants for nonprofits in South Carolina supporting general operating expenses

100+ Unrestricted grants for nonprofits in South Carolina supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

1,000+ Grants on Instrumentl focused on Environment

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Unrestricted grants for Nonprofits in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
26.6%
Q3
24.1%
Q4
20.4%

Typical Funding Amounts

What's the typical grant amount funded for Unrestricted Grants for Nonprofits in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$530,911 $530.9 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Unrestricted Grants for Nonprofits in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Unrestricted Grants for Nonprofits in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Unrestricted Grants for Nonprofits in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081