Best St. Paul Grants for Nonprofits in Minnesota

The ASF Family Fund Grant, offered by the Angelman Syndrome Foundation, provides crucial financial assistance to families of individuals with Angelman syndrome. This rare neuro-genetic disorder affects approximately 500,000 people globally. The fund aims to enhance the quality of life for affected individuals, allowing caregivers to apply for up to $5,000 to cover essential needs. Limitations include restrictions on certain expenses and prior grant awards. This initiative aims to support families through education and necessary resources.

The James Madison Graduate Fellowship supports U.S. citizens pursuing master's degrees focused on the Constitution, enhancing their constitutional knowledge for teaching. Fellows are required to teach American history, government, or civics at the secondary level for one year per funding year. Financially, the fellowship awards up to $24,000, covering tuition and fees, and must be repaid if fellowship conditions are unmet. This program ensures future educators embody constitutional principles in their teaching.

The Valley Hospital Auxiliary has been supporting future healthcare professionals since 1961 by providing scholarships to high school seniors and undergraduate students. In 2025, they awarded $30,000 to 21 exceptional students who have shown academic excellence and a commitment to healthcare. This initiative not only benefits the recipients but also contributes to the community by nurturing the next generation of medical leaders. Eligible high school students can reapply throughout their college years, ensuring continuous support for their educational journeys.

The VFW's Sport Clips Help A Hero Scholarship offers financial support of up to $5,000 to eligible veterans and service members pursuing their educational goals. This initiative, backed by the Veterans of Foreign Wars organization, aims to alleviate the burden of student debt for those who have served our country. By partnering with Student Veterans of America and Sport Clips, the VFW ensures that veterans receive the assistance they deserve to succeed in their academic endeavors.

The Truman Scholarship, established by the Truman Foundation, supports college juniors committed to public service. It offers up to $30,000 for graduate studies, alongside mentoring and career development opportunities. Ideal candidates demonstrate leadership, a strong commitment to public service, and the potential for success in graduate school. This prestigious award aims to cultivate future leaders dedicated to making a positive impact in their communities and beyond.

The PCORI Call for Proposals for HSII Implementation Projects invites innovative approaches to address barriers in healthcare settings. These projects should enhance practice change through active, multi-component strategies and include rigorous evaluations to measure implementation effectiveness. While developing tools to support these strategies is permitted, it should not be the main focus. Successful proposals will demonstrate their potential impact on healthcare outcomes and patient experiences.

The MHC Community Identity & Heritage Festival Grants support diverse cultural communities in Minnesota by funding community events, music and jazz festivals, and cultural festivals featuring art installations and performances. These grants aim to enhance cultural engagement and celebrate the rich heritage of local communities, providing opportunities for individuals and organizations to showcase their artistic talents and foster community connections through vibrant festivals.

The Ollie Hinkle Heart Foundation's Technology Grant aims to improve pediatric heart care outcomes through innovative collaborations. By focusing on predictive technologies for early recognition, precision for personalized care, and preventive measures for quality of life, the foundation seeks to transform care for heart children and their families. Their mission emphasizes community support, education, and advocacy to ensure no family faces unmet needs alone, creating a legacy of love and courage in the heart community.

The Implementation Awards by PCORI aim to fund projects that translate patient-centered research into real-world practices. With budgets up to $2.5 million for implementation projects lasting up to 48 months, applicants must present a clear plan for broad evidence uptake. Additionally, those proposing implementation projects need an accepted Draft Final Research Report related to their original PCORI-funded research to qualify for funding.

This funding opportunity aims to enhance the development of medical products in rare diseases through innovative natural history studies. By generating high-quality data, the FDA seeks to bridge critical knowledge gaps and eliminate barriers in rare disease research. The initiative focuses on diseases with unmet needs, fostering significant impacts for those affected and facilitating the development of effective therapeutic solutions.

The NARMS Cooperative Agreement Program aims to enhance antibiotic resistance surveillance in retail food specimens. Funded by the FDA, this initiative strengthens the National Antimicrobial Resistance Monitoring System established in 1996. By improving detection methods and expanding sampling sites, the program seeks to protect public health and align with NARMS objectives, ultimately combating the growing threat of antibiotic resistance in food commodities.

The RFA-FD-23-001 funding opportunity aims to support clinical trials for orphan products targeting rare diseases. It focuses on evaluating the efficacy and safety of treatments to address unmet medical needs. By promoting innovative and collaborative trial designs, the FDA seeks to enhance the approval rates of effective therapies for rare conditions, ultimately benefiting patients and advancing drug development in this critical area.

The Yéigo Action Grant, provided by the First Peoples Fund, offers financial support ranging from $100 to $2,500 for Native artists and culture bearers facing hardships that affect their creative practices. This grant aims to assist artists with specific professional opportunities, such as workshops or emergencies. By honoring the spirit of encouragement embodied in the Diné word 'yéigo', the grant helps ensure that artists can continue their vital work within their communities.

The Rooted Pathways Program, initiated by First Peoples Fund, offers essential support to Native-led arts organizations, fostering their growth and stability. This funding empowers these organizations to thrive in their missions, providing unrestricted operating support and participation in a Learning Cohort. Eligible applicants include Native nonprofits and collectives with budgets under $500,000, and the program aims to uplift artists from U.S. federally recognized tribes. This initiative is part of the Wallace Foundation's broader commitment to enhancing well-being in the arts.

The Eugene C. Figg, Jr. Civil Engineering Scholarship, established by Figg Engineering Group in 2002, honors the legacy of Gene Figg, who was renowned for his artistic bridge designs. This scholarship aims to support undergraduate civil engineering students with a passion for bridge design and construction, facilitating their education in an ABET-accredited program. Eligible candidates must be U.S. citizens and Student Members of the American Society of Civil Engineers in good standing.

The Outdoor Fund - Local Impact Grant supports local organizations and projects that enhance community engagement and align with conservation goals. With grants up to $5,000, eligible projects include youth fishing clinics and trail maintenance. Funded by Bass Pro Shops and Cabela’s, this initiative exemplifies their commitment to wildlife conservation and connecting communities to the outdoors. Eligible applicants include municipalities and registered nonprofits in the U.S. and Canada, focusing on specific conservation efforts.

The Community Foundation of Grant County offers over 120 scholarship opportunities for U.S. citizens and eligible noncitizens pursuing higher education at accredited institutions. With more than $1 million awarded annually, the foundation supports students of all backgrounds and academic abilities. Scholarships are competitive and aimed at covering qualified educational expenses, including tuition and fees. Applicants are encouraged to collaborate on proposals, enhancing community impact through education and development.

The Creative Connections Grant offers up to $5,000 for artistic projects in Minnesota, encouraging individual artists to promote access to the arts and engage with local communities. Eligible proposals should focus on connecting residents with cultural experiences, integrating artistic engagement with community goals, providing arts learning opportunities, or sharing expressive cultural traditions. This grant aims to enhance the vibrancy of Minnesota’s artistic landscape through diverse and impactful projects.

The Stephen J. White Prize, established by the American Philosophical Association, honors the late Dr. Stephen J. White and is awarded biennially to the best published paper by a junior philosopher. It focuses on themes central to Professor White's work, such as moral responsibility and practical reasoning. The winner receives a $1,000 monetary award and a symposium at an APA divisional meeting, recognizing significant contributions in philosophy.

The Indigenous Tomorrows Fund (ITF) is a youth-led initiative by Native Americans in Philanthropy aimed at supporting Indigenous youth leadership and community-driven solutions. In its 2025 pilot year, ITF will award up to 24 grants of $30,000 each to projects that enhance cultural continuity and sustainable futures. Priorities include promoting food justice, advancing community health, and strengthening cultural connections, particularly those addressing inequity and fostering long-term healing.

The Tuttleman Foundation, established in Philadelphia in 2003, provides grants ranging from $1,000 to $250,000 to 501c3 organizations. Guided by the legacy of Stanley and Edna Tuttleman, the foundation focuses on areas such as education, community building, health care, arts and museums, basic human services, and spirituality. Their engaged philanthropy aims to support enduring benefits for the communities they serve, reflecting the founders' commitment to impactful giving.

The Murray Watson, Jr. Scholarship offers a $5,000 award each month to Texas students. Funded by Brazos Higher Education, this scholarship aims to support students in achieving their college dreams, whether they are high school seniors or current college attendees. Eligibility includes being a Texas resident with a minimum GPA of 3.3. This initiative is part of Brazos' commitment to making education more accessible and affordable for Texas families.

Better Health Together (BHT) is committed to enhancing community wellness through sponsorships. By collaborating with over 100 organizations in eastern Washington, BHT addresses critical health issues and supports events that elevate community voices. Organizations seeking funding should submit applications at least 6–8 weeks prior to their event to ensure timely review. BHT values partnerships that align with its mission and aims to invest in innovative solutions for community health challenges.

The Johns Hopkins Merkin Peripheral Neuropathy and Nerve Regeneration Center offers Seed Grants for innovative research on peripheral neuropathy and nerve regeneration. These grants support high-risk, high-reward pilot projects addressing axon degeneration and Schwann cell dysfunction. Researchers may apply for funding of up to $75,000 per year for one or two years. The initiative aims to foster novel ideas and successful transitions to external funding, enhancing scientific understanding and therapeutic development.

The Pizza Hut Foundation is offering scholarships for students demonstrating financial need and community leadership. Eligible applicants must be U.S. residents aged 17-26, enrolled in accredited post-secondary education for Spring 2026, and maintain a minimum GPA of 2.5. Scholarship amounts range from $500 to $5,000, with distribution to be made in Spring 2026. The application period runs from July 8 to September 5, 2025, with notifications for recipients by November 17, 2025.

The Clinical & Translational Science Award TL1 Postdoc Fellowship Training Grant offers comprehensive support for biomedical researchers at Vanderbilt University. This program empowers scholars through career development tools, mentoring opportunities, and participation in national Translational Science meetings. Trainees must hold a doctoral degree and be committed to translational research while pursuing full-time training. This fellowship fosters innovation and collaboration among researchers, enhancing their contributions to the field.

The Gerald & Sybil Cohen Family Foundation Scholarship aims to ease the financial burden of college costs for students pursuing education in STEM fields. Open to U.S. citizens aged 18 and older with a minimum GPA of 3.5, the scholarship is available for public colleges and universities. Preference is given to dependents of former employees of Information Builders, Inc. Awards are not guaranteed and may vary in amount.