Best Grants for Nonprofit Healthcare Programs in Texas

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The Middle Run Foundation is a family-governed foundation based in Newark, Delaware. The Board of the foundation is chaired by Sarah Ives Gore, its founder, and includes her children, grandchildren, and non-family members who bring experience and expertise to our work.

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Purpose:

The purpose of the foundation is to fund and support non-profit programs which focus on building healthy, self-sufficient families.

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The Middle Run Foundation makes grants up to $500,000 annually with individual grants ranging from $5,000 to $50,000.

Mission

To empower worthy nonprofits by providing critically needed, unrestricted funding that helps them fulfill their missions with confidence and sustainability.

How We Serve Nonprofits

AmFund partners with nearly 800 organizations annually—supporting causes related to health, education, the arts, human services, animal welfare, and more. We’re known for our:

• Signature silent and live auctions featuring once-in-a-lifetime travel experiences.
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• No-cost platform development for virtual and hybrid fundraising
• In-house travel specialists who provide custom planning, extensions, insurance, and 24/7 emergency support.
• Ongoing educational resources, grants, and consulting support for nonprofit development.

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Our model is built on relationship, trust, and results. Every trip sold, every service provided, and every donor interaction is designed to maximize your fundraising impact—without adding burden to your team.

The GoodRx Helps Community Catalyst Grants support community-led nonprofits dedicated to enhancing health and well-being for under-resourced groups. This funding aims to improve healthcare access, education, and essential services, addressing systemic barriers faced by these communities. Eligible organizations must demonstrate a commitment to community empowerment and possess a minimum annual operating budget of $250K. This initiative underscores the importance of fostering sustainable health improvements through targeted, inclusive support.

The Cancer-Related Behavioral Health Fund, established by the HealthWell Foundation, provides financial assistance to individuals diagnosed with cancer for behavioral health treatments. This fund covers costs associated with prescription drugs, counseling services, and transportation. Aiming to alleviate financial burdens, it ensures that underinsured patients can access necessary care without delay. In 2024, the foundation awarded over $1.2 billion, emphasizing its commitment to improving health outcomes for cancer patients across the United States.

The Chronic Lymphocytic Leukemia Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients battling chronic lymphocytic leukemia (CLL). This fund provides essential support for prescription copays and premiums, ensuring that patients can access necessary treatments without the stress of financial constraints. Since its inception, the foundation has awarded over $1.2 billion in grants, helping more than 1.1 million patients. The initiative emphasizes the importance of accessible healthcare and aims to improve the quality of life for those affected by this condition.

The Congenital Sucrase-Isomaltase Deficiency Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from this genetic disorder. By providing assistance with prescription drugs and treatment costs, the fund ensures that vital medications are accessible, allowing patients to manage their condition effectively. In 2024, the Foundation is expected to award over $1.2 billion in grants, showcasing its commitment to enhancing healthcare access for those in need.

The Cushing's Disease or Cushing's Syndrome Fund, operated by the HealthWell Foundation, provides vital financial assistance to underinsured patients facing high medical costs associated with these conditions. The fund covers co-payments, insurance premiums, and necessary treatments, ensuring that patients receive the care they need without financial burden. With an average grant utilization of $3,000 over twelve months, this fund aims to alleviate the challenges of treatment accessibility, supporting both physical and mental health for those affected.

The Dupuytren’s Disease Fund, managed by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from Dupuytren's Disease. This fund provides assistance for prescription drug copays and insurance premiums related to treatment. With an average grant utilization of $1,650 over a 12-month period, the fund ensures that essential medications and therapies are affordable. HealthWell Foundation, a private non-profit, has helped over 1.1 million patients since 2004, demonstrating its commitment to healthcare access.

The Emergency/Medical Workers Behavioral Health Fund aims to support emergency workers facing trauma and anxiety due to their roles. Established by the HealthWell Foundation, it provides financial assistance for treatment-related costs, including copayments for prescription drugs, counseling, and transportation. In 2024, the Foundation awarded over $1.2 billion to underinsured patients, ensuring no one is denied essential healthcare due to financial barriers. This initiative helps address the critical mental health needs of those who serve on the front lines.

The Hyperoxaluria Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from hyperoxaluria, a condition characterized by excessive oxalate in urine. This fund assists with prescription drug copays and insurance premiums, providing vital support for treatments. In 2024 alone, HealthWell allocated over $1.2 billion in grants, ensuring access to essential medications for those in need. The organization is committed to improving healthcare access and reducing disparities for affected individuals.

The HealthWell Foundation's Inborn Metabolic or Genetic Bile Acid Deficiency Vitamins and Supplements Fund provides essential financial assistance for individuals facing significant health challenges. By covering copays, deductibles, and related expenses, the fund aims to alleviate the financial burden on underinsured patients. With a commitment to enhancing healthcare access, the Foundation has awarded over $1.2 billion since its inception, ensuring that vital treatments remain accessible to those in need.

The Mantle Cell Lymphoma Fund, managed by the HealthWell Foundation, provides financial assistance to underinsured patients diagnosed with Mantle Cell Lymphoma. The fund covers prescription drug copays and Medicare Part B premiums, with a maximum award of $8,500. Eligible patients must have insurance that covers their medication and meet specific income guidelines. The foundation aims to reduce financial barriers to essential treatments, ensuring that patients receive necessary care without undue financial strain.

The Metabolic Dysfunction-Associated Steatohepatitis Fund, established by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients facing chronic illnesses. It provides critical support for expenses related to prescription copays, insurance premiums, and transportation for treatment. With a maximum award of $8,000, the fund ensures that individuals can access necessary healthcare services without financial strain. This initiative emphasizes the commitment to improving health outcomes for those affected by metabolic dysfunction-associated steatohepatitis.

The Porphyrias Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from porphyrias, a group of eight disorders characterized by the accumulation of porphyrins in the body. The fund assists with prescription drug copays and insurance premiums, offering up to $4,000 in financial aid. Established to ensure no patient lacks necessary treatment due to costs, the foundation has awarded over $1.2 billion since 2004, supporting more than 1.1 million patients.

The Systemic Sclerosis with Interstitial Lung Disease Fund, managed by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from systemic sclerosis. This rare autoimmune disease leads to excessive collagen production, causing serious health issues. The fund assists with prescription copays and insurance premiums to ensure patients receive necessary treatments. In 2024, HealthWell awarded over $1.2 billion in grants, supporting more than 1.1 million patients in accessing vital healthcare services.

The Waldenstrom Macroglobulinemia Fund provides crucial financial assistance to underinsured patients suffering from this rare blood cancer. Through the HealthWell Foundation, the fund helps cover prescription copays, insurance premiums, and treatment-related costs, ensuring access to necessary medical care. With over $1.2 billion in grants awarded, the program has supported more than 1.1 million patients since its inception in 2004. Its mission is to alleviate financial barriers to essential healthcare, allowing patients to focus on their treatment and recovery.

The Peyronie's Disease Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from Peyronie's disease. This condition involves the formation of fibrous scar tissue in the penis, leading to painful erections and erectile dysfunction. The fund provides financial assistance for prescription drugs and related healthcare costs, ensuring that patients receive necessary treatment without the stress of high out-of-pocket expenses. HealthWell is committed to improving access to essential healthcare for America’s underinsured population.

The BJA FY 2026 Adult Treatment Court Program aims to enhance Adult Treatment Court operations, focusing on preventing overdoses and reducing substance use among high-risk adults in the criminal justice system. The program integrates judicial supervision, substance use disorder treatment, and recovery support services to improve outcomes for participants. This funding opportunity from the U.S. Department of Justice highlights the commitment to public safety and addressing critical issues like the opioid crisis.

The Musicians Foundation Grant provides financial assistance to professional musicians in need, covering medical and dental bills, living expenses, and other essential costs during emergencies. Applicants must demonstrate at least five years of professional experience and apply for reasons beyond loss of work. The grants are issued as vendorized checks to ensure immediate support. This program is not designed for COVID-19 assistance or general income support, focusing instead on urgent hardship cases.

The R.F. and Jessie Shaw Foundation Grant, administered by the East Texas Communities Foundation, supports charities primarily in Rusk County, Texas, focusing on wellness, healthcare, and education. Established in memory of Dr. Shaw and Jessie Lewis, the grant aims to continue their legacy of community support. Applications are by invitation only, with the application link sent out on October 1, 2025, and the deadline for submissions is October 31, 2025, at 5:00 p.m.

The Dr. Susan Holstine Behavioral Health Professions Scholarship, established in 2022 by the Chuckanut Health Foundation, honors Dr. Holstine's commitment to accessible behavioral health services. This scholarship aims to support local students pursuing careers in behavioral health, alleviating financial barriers and empowering the next generation. By investing in education, we strengthen our community and encourage future leaders in mental health care.

The Open Grant Cycle: Small Grant Track invites proposals from organizations serving communities within a 74-county area. The initiative prioritizes collaboration, community perspectives, and systemic change to support underserved populations. Eligible organizations must be IRS-recognized nonprofits with a commitment to local service. This streamlined application process aims to enhance access to funding, fostering nonprofit capacity and impactful projects in focus areas like housing, education, and health equity.

The Leigh Carter Scholarship Fund, established by the Tennessee Chiropractic Association, honors Leigh Carter's dedication to learning. This scholarship provides financial support to full-time students pursuing chiropractic education at accredited colleges. Applicants must show a strong interest in health care, and preference is given to Tennessee residents. Recipients can reapply throughout their four-year degree program, ensuring continued support for their educational journey in the chiropractic field.

The nccPA Health Foundation's Diversity, Equity, and Inclusion - PAs STEP Up Grant aims to empower PAs and PA students to create initiatives that enhance diversity and foster inclusive practices within the PA profession. With funding up to $2,500, this grant encourages projects that raise awareness of the PA profession among underrepresented groups, ultimately striving to reduce health disparities and promote equity. Applications are accepted year-round, providing ongoing support for impactful community-driven efforts.

The nccPA Health Foundation: Equitable Care - Be the Change Grant supports PAs and PA students in implementing projects that improve health access and promote equity in their communities. With a focus on addressing health disparities, applicants can receive up to $2,500 to fund innovative initiatives. Applications are accepted year-round, enabling ongoing support for transformative health solutions aimed at fostering equitable care for underserved populations.

The nccPA Health Foundation: Kathy J. Pedersen Grant aims to promote equitable health care by providing up to $5,000 for innovative projects that address health disparities. This grant honors Kathy J. Pedersen's legacy and encourages applicants to develop actionable strategies that foster cultural humility, advocate for underserved populations, and improve public health. Grantees are expected to demonstrate a commitment to sustainability and social accountability in their proposed initiatives.

The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.