Best Health Care Grants in Texas

Utilizing the Full Power of Empire AI Request for Applications

The Simons Foundation (SF) intends to support cutting-edge mathematics and basic science research, drawing on the advanced computational power of the Empire AI.

Toward this goal, SF plans to initiate a new program to fund six to 12 proposals through a competitive open call to the Empire AI research community.

A successful proposal will outline an ambitious two-year research program in one of the following fields, or at their intersections: computational astrophysics and physics, computational biology, mathematics, neuroscience and computational physical chemistry. Each proposal will necessarily rely on the development and utilization of foundational machine learning models, aimed at solving problems of fundamental importance in the above-listed disciplines.

Computational biophysics, neuroscience, ecology and evolution, plant biology, optimal transport, multiscale physics, fluid dynamics and numerical general relativity are representative examples of fields that could use multinode clusters of GPUs of Empire AI, which is a requirement of the program. All submitted proposals should detail how their work will use multinode clusters of GPUs in Empire AI. Proposals focused on data curation and creation of datasets can be considered in exceptional cases, as long as the attained data will be used by the proposers for solving scientific problems as part of the same proposal.

The program’s total budget is expected to be $6 million USD over a two-year period.

Funding

Award Amount: There is no maximum budget total for an individual award. The total amount requested should reflect the proposed research. All award amounts are inclusive of indirect costs (see our grant policies). Please note that we anticipate funding six to 12 applications. The total program’s budget of $6 million USD over two years will be spread across all awards.

Award Duration: June 1, 2027, through May 31, 2029.

Number of Awards: We expect to select six to 12 applications for funding.

The Affordable Rural Cooperative (ARC) Energy Program, initiated by the Rural Utilities Service (RUS), aims to enhance rural electric systems through substantial funding of approximately $175 million. This initiative focuses on increasing emission-free nuclear power and improving transmission infrastructure efficiency, promoting long-term reliability and affordability. Eligible entities include electric cooperatives serving rural areas and their subsidiaries. The program aligns with the Inflation Reduction Act (IRA) to achieve significant reductions in greenhouse gas emissions, thus fostering a sustainable energy future.

Greenawalt Foundation

Our Mission

The Greenawalt Foundation advances opportunities in the skilled trades through funding for accredited pre-apprenticeship and apprenticeship programs, workforce training initiatives, and youth career exploration experiences. These programs promote technical readiness and connect STEM education to modern trades careers, building a stronger, more sustainable workforce. Foundation support focuses on expanding access and creating equitable pathways to prosperity for individuals pursuing skilled trades careers. Through these efforts, the Foundation helps develop the next generation of skilled professionals who will shape the future of our communities.

Community Grant

The Greenawalt Foundation extends its commitment to opportunity and well-being through community grants that support nonprofit organizations serving women, children, and vulnerable populations. These grants focus on programs that promote safety, stability, and self-sufficiency, including initiatives supporting domestic violence recovery, foster care, the working poor, and animal welfare. Foundation support strengthens the social fabric of communities and expands access to essential resources for those in need. Through these efforts, the Foundation helps build stronger, more compassionate communities where individuals and families can thrive.

Areas of Support

We focus our community grants on initiatives that align with our mission of compassion, opportunity, and empowerment. Areas of support may include:

• Domestic violence prevention and survivor support
• Programs for women and children
• Family assistance and poverty relief initiatives
• Foster care, youth development, and educational support
• Animal welfare and community-based rescue programs

Greenawalt Foundation

Building Stronger Communities

At The Greenawalt Foundation, we believe that opportunity is the foundation of prosperity. By supporting organizations that educate, train, and empower people in the trades, we’re helping to build a stronger, more sustainable future for all.

Skilled Trades Grant Opportunities

The Greenawalt Foundation advances opportunities in the skilled trades through funding for accredited pre-apprenticeship and apprenticeship programs, workforce training initiatives, and youth career exploration experiences. These programs promote technical readiness and connect STEM education to modern trades careers, building a stronger, more sustainable workforce. Foundation support focuses on expanding access and creating equitable pathways to prosperity for individuals pursuing skilled trades careers. Through these efforts, the Foundation helps develop the next generation of skilled professionals who will shape the future of our communities.

Eligible Grant Categories

• Skilled Trades Training Support
• Pre-Apprenticeship or Apprenticeship Programs
• Youth Career Exploration Camps

Seeding Research, Networking, and Capacity Building at Minority-Serving Institutions

Introduction & Purpose

RWJF is committed to ensuring everyone has a fair and just opportunity to be as healthy as possible. To achieve this goal, we support research that examines the historical and systemic factors that cause health inequities. Some of those determinants are poverty, discrimination, and limited access to quality education, housing, safe environments, and healthcare. As attacks on data and academic freedom and ongoing funding cuts to federal health equity research and programs continue, philanthropy’s work to achieve fair and equitable health, including a more equitable research funding ecosystem, is more important than ever. While philanthropic support for Minority-Serving Institutions (MSIs) has increased in recent years, there is more to be done to rectify historical disparities in funding. 

This call for proposals (CFP) provides support to health equity research centers at MSIs to strengthen research infrastructure and capacity-building. Capacity-building will help develop staff, skills, culture, resources, and systems that enable research to happen effectively. Specific work that RWJF may fund under this CFP includes specific skill or methodology training; faculty release time; support for research assistants, advisors, and project staffing; mentoring, professional development and collaboration, and more.

Through this CFP, RWJF will expand its efforts to transform deeply rooted beliefs about which data and research methods are valued, whose perspectives are prioritized, and which populations deserve resources. By supporting the infrastructure and capacity-building needs of MSIs, this opportunity strengthens their ability to generate critical evidence and to cultivate transformative, actionable solutions toward health equity. 

RWJF believes in health equity research that is grounded in systems thinking; supports and disseminates evidence identifying and implementing structural solutions to racial and health inequities. This CFP seeks mission-aligned institutions to participate in cohort-style peer learning to advance their ability to engage in health equity research and apply for competitive funding opportunities in the future.

Although no single philanthropy can fill the gap left by federal funding cuts, this CFP demonstrates strong support for research, historically underrepresented researchers, and research centers that are positioned to pave the way toward a future where health is not a privilege, but a right.

The Cooperative Endangered Species Conservation Fund: Recovery Land Acquisition Grant Program, initiated in FY 2001, aims to foster collaboration between State and Federal entities in conserving listed species. This program provides funding for acquiring critical land parcels to support U.S. Fish and Wildlife Service-approved recovery plans. By securing habitats at risk from development, the initiative directly addresses the primary threat to endangered species, ensuring effective and immediate conservation actions.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of biological processes driven by somatic mutations in human tissues through innovative technology development. Since its inception in 2023, the program has produced multi-omic datasets from human tissues representing all germ layers. The NIH is now advancing to Stage 2, focusing on collaborative efforts to refine and implement validated technologies for somatic mutation detection and functional interpretation, promoting rigorous and cost-effective methodologies.

The Cancer Prevention and Control Programs aim to eliminate cancer through collaborative efforts among state, territorial, and tribal organizations. Funded by the CDC, this program supports initiatives such as breast and cervical cancer screening, cancer control planning, and cancer surveillance. By fostering partnerships and community involvement, the program seeks to improve health outcomes and achieve the mission of 'All People Free of Cancer.' This comprehensive approach ensures that resources are effectively coordinated to address the cancer burden in communities.

This funding opportunity from the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to advance mechanistic research on metal exposure and its effects on human health. Studies should focus on biological processes altered by metals, including their absorption, transport, and immune interactions. Innovative methodologies and human biospecimens are encouraged to explore how metals might impact immune homeostasis and cross biological barriers, providing insights into health risks associated with metal exposure.

The TURTLE Program aims to empower Tribal Entities by fostering a skilled workforce in biomedical research. It supports undergraduate and graduate students in health research, ensuring they complete their degrees and transition into impactful careers. With phased awards, the program emphasizes effective training and mentoring, inviting eligible organizations to apply. Applications will undergo NIH's peer-review process, ensuring only the most meritorious proposals are funded, ultimately enhancing Tribal health research capabilities.

The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of somatic mutations and their impact on human biology and disease. This initiative will establish a Tissue Procurement Center (TPC) to collect and provide clinically relevant tissue samples from a diverse set of healthy donors. The TPC will support ongoing research by ensuring high-quality, well-characterized specimens are available for functional analyses, advancing the field of somatic mosaicism.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance understanding of biological processes and disease mechanisms due to somatic mutations in human tissues. Since 2023, it has produced multi-omic datasets from various human tissues. The NIH plans to advance this initiative by establishing the National Somatic Mosaicism Commons Data Analysis & Organizational Center, which will oversee data management, develop analytical tools, and provide training to facilitate research and clinical applications.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to uncover biological processes and disease mechanisms influenced by somatic mutations. Since its inception in 2023, it has produced valuable multi-omic datasets from diverse human tissues. The upcoming Stage 2 Genome Characterization Centers will focus on understanding the impact of these mutations in both healthy and clinically significant samples, enhancing our knowledge of somatic mosaicism's role in human health and disease.

Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease

The Challenge

Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).

The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.

This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.

The National Institutes of Health (NIH) is continuing support for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), which focuses on clinical trials and biomarker validation studies for neurological disorders. This initiative aims to foster innovation in neurotherapeutics by providing essential infrastructure and expertise. The program encourages the establishment of Clinical Coordinating Centers (CCC) and Data Coordinating Centers (DCC) to enhance collaborative efforts. Note that applications are not currently being solicited.

The Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center aims to enhance diagnosis and research for individuals with undiagnosed diseases. This initiative focuses on engagement, education, and innovative diagnostic approaches. The center will oversee recruitment, participant support, and data management while fostering collaboration among various stakeholders. NINDS seeks proposals demonstrating the necessary infrastructure and partnerships to ensure effective implementation of the UDN's mission and transfer successful diagnostic methods into mainstream healthcare.

The Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center (DRIC), supported by NINDS, aims to enhance diagnostic capabilities for UDN participants. This initiative will foster collaboration among clinical networks and stakeholders to develop innovative diagnostic tools and strategies. The DRIC will also focus on the systematic evaluation of unresolved UDN cases, advancing genomic and non-genomic diagnostics, and discovering novel disease-associated genes. This forecast allows potential applicants to prepare and collaborate effectively for future projects.

The NIH Stroke Clinical Trials Network (StrokeNet) aims to enhance stroke treatment through regional clinical enrollment coordinating centers (RCCs). Supported by the National Institute of Neurological Disorders and Stroke (NINDS), this initiative promotes collaboration for clinical trials that focus on acute stroke treatment, prevention, and rehabilitation. While applications are not currently being solicited, this notice serves to prepare potential applicants for future opportunities in advancing stroke care.

The Undiagnosed Diseases Network (UDN) aims to enhance diagnostic excellence through multiple clinical Networks of Diagnostic Excellence (NODEs). These NODEs will operate as regional networks, leveraging partnerships with various healthcare facilities to provide participant-centered evaluations for complex conditions. They will also engage in research and training to improve diagnostic tools and strategies. This initiative encourages collaboration and aims to improve the overall experience and access for participants in need of specialized care.

The National Institutes of Health (NIH) is continuing its support for the NeuroNEXT initiative, which focuses on conducting clinical trials and biomarker validation studies for neurological disorders. This infrastructure aims to foster innovation and enhance the development of effective neurotherapeutics for both adult and pediatric populations. While applications for network clinical research sites are not currently being solicited, this notice allows potential applicants to prepare collaborative and responsive applications.

The Homeless Veterans' Reintegration Program (HVRP) aims to assist veterans experiencing homelessness by providing tailored employment services. This federal initiative focuses on helping veterans transition to stable employment through job training, case management, and connections to local supportive services. HVRP aligns with national priorities to enhance career outcomes for veterans, ensuring they receive the necessary tools and resources for sustainable employment and integration into the workforce.

The Native Public Health Resilience (NPHR) program is a new funding opportunity aimed at supporting Tribes and Tribal Organizations in delivering essential public health services. Sponsored by the Indian Health Service, this initiative seeks to bolster public health infrastructure and resilience within tribal communities, ensuring they have the necessary resources to address health challenges effectively. Eligible applicants will receive financial assistance to enhance their public health capabilities and improve community health outcomes.

The NIH Stroke Clinical Trials Network (StrokeNet) aims to enhance stroke treatment and recovery through a robust national infrastructure. Funded by the National Institutes of Health, this initiative focuses on clinical trials that evaluate innovative therapies for stroke patients and those at risk. The program is currently not soliciting applications but encourages the development of collaborations to support the national coordinating center and data management efforts, ultimately improving outcomes for individuals affected by stroke.

The NIDA Avenir Program aims to cultivate innovative leaders in addiction science by funding exceptional early stage investigators (ESIs) embarking on pioneering research. Launched in 2015, this initiative encourages high-risk, high-reward mechanistic studies related to Substance Use Disorders (SUDs) across diverse scientific domains. Applications from new investigators and those outside addiction research are welcomed, fostering interdisciplinary approaches that enhance understanding of SUD mechanisms. The program supports ESIs who may lack preliminary data but demonstrate potential for impactful contributions.

The BRAIN Initiative aims to advance innovative neurotechnologies by funding early-stage clinical studies for devices that record or stimulate the human central nervous system. This initiative encourages collaborations between clinical researchers and device manufacturers to facilitate groundbreaking studies. By addressing the challenges of obtaining safety and utility data, this program supports both non-invasive and significant risk devices, providing essential insights into their functionality and design. Applications are currently not being solicited, allowing time for meaningful project development.

The BRAIN Initiative, led by the NIH, aims to advance neurotechnologies at institutions with limited NIH funding. This funding opportunity encourages collaboration and knowledge transfer to integrate innovative neurotechnologies into research and training programs. While applications are currently not being solicited, potential applicants should start developing partnerships and projects in preparation for future submissions. This initiative will enhance the dissemination of BRAIN technologies and support novel research practices.