Best Alexandria Grants for Nonprofits in Virginia

About Us

Children’s Cancer Research Fund is a national nonprofit dedicated to ending childhood cancer. Our main focus is to support the research of bright scientists across the country whose ideas can make the greatest impact for children fighting cancer. We also fund resources and programs that help kids and families as they navigate the difficult experience of cancer treatment and survivorship.

Since 1981, we’ve contributed over $235 million to research, support programs for children and families, and awareness and education outreach. In 2024, over 81 percent of funds raised went directly to these program services areas.

Children’s Cancer Research Fund (CCRF) is a national nonprofit committed to finding safer, more effective therapies for kids battling cancer. Thanks to donors and partners around the country, we have contributed over $235 million to research, education and awareness, and quality-of-life programs for childhood cancer families. We believe kids deserve safer, less toxic treatments, and we’re committed to funding groundbreaking research and services that enhance healing and care.

In 2026, Children’s Cancer Research Fund will focus our research funding efforts on three main areas:

• Hard-to-Treat Cancers
• Survivorship
• Health Disparities

Accelerating Hope: Clinical Trials for Hard-to-Treat Cancers Award

This funding opportunity is limited to support for clinical trials focused on hard-to-treat cancers, prioritizing Phase 0 – Phase 2 studies. Learn more about eligibility criteria and other key details below.

Barbara McDowell Social Justice Center Inc.

The Barbara McDowell Social Justice Center litigates, educates, advocates, and provides grants to nonprofits to eradicate social injustices. 

We pursue litigation through our own efforts as well as funding others in the following fifteen issue areas: Access to Benefits, Children’s Rights, Disability Rights, Discrimination, Domestic Violence, Due Process, Environmental Justice, Healthcare, Homelessness, Housing, Native American Rights, Prisoners’ Rights, Refugee and Immigration Rights, Voting Rights, and Veterans’ Rights.

Barbara McDowell Social Justice Center Grant

We make grants to organizations that undertake systemic social justice litigation across fifteen issue areas. The Center funds litigation matters that are consistent with our namesake Barbara McDowell’s past legal efforts and her beliefs regarding social justice.

Applications must be for a specific social justice legal case, including the filing of an appeal. Grant funds are to be used only for attorney time charges and litigation expenses related to the specific case for which an organization is applying to be funded. 

Disabled Veterans National Foundation

The Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability.

Guided by this commitment, DVNF developed its Health & Comfort programs, offering emergency financial assistance, housing transition support, food assistance, comfort kits, and wellness initiatives. These programs are designed to meet veterans where they are and to provide practical solutions that restore hope and stability. Today, DVNF continues to grow as a trusted national nonprofit. Every day, our team works with a clear purpose: to change lives for the men and women who have served our country.

Homeless To Housing Program - Household Comfort Support

DVNF is dedicated to assisting disabled and at-risk veterans in their transition from homelessness to permanent housing. Recognizing that securing a home is a significant milestone, DVNF understands that true stability is achieved when a house becomes a home, furnished with essential items that provide comfort and functionality. We help cover essential costs related to securing and creating comfortable housing for at-risk veterans.

The H2H Program offers comprehensive support to veterans by providing: Household Comfort Support of up to $2,000 worth of essential household items to ensure veterans have a stable, safe, and comfortable living environment.

For Financial Assistance: Payments are processed through two payment cycles each month, around the 15th and 30th. For Furniture Assistance: Once the List of Items form is completed, DVNF staff will purchase the requested items, which should arrive within 7-10 business days.

MIND (Maximizing Innovation in Neuroscience Discovery) Prize

The Pershing Square Foundation’s (PSF) brain initiative funds cutting-edge research that revolutionizes our ability to predict, prevent, and treat neurodegenerative diseases (NDDs). Advancing our fundamental understanding of the brain and cognition to ultimately combat neurodegeneration and related diseases is a goal of increasing urgency. Breakthroughs in basic scientific and translational research will yield critical tools for and knowledge of NDDs, including Alzheimer’s Disease and Dementia, which affect millions of people worldwide.

The MIND (Maximizing Innovation in Neuroscience Discovery) Prize supports and empowers early-to-mid-career investigators to rethink conventional paradigms around NDDs. Modeled after the Pershing Square Sohn Prize for Young Investigators in Cancer Research, the MIND Prize catalyzes interdisciplinary approaches and facilitate collaborations across academic departments and institutions. It fuels the groundbreaking research that will accelerate our understanding of NDDs at every level.

Projects may range from the invention of novel tools, techniques, and technologies for mapping and analyzing the brain to bold approaches that demonstrate extraordinary therapeutic potential. Research domains may include—but are not limited to—neurobiology, brain imaging and mapping, machine learning, drug delivery, and synthetic biology. Applicants are encouraged to propose bold, hypothesis-driven, high-risk, high-reward research with the potential for transformative impact. Tool and technology development are permitted when they support the testing of a clearly defined biological hypothesis. Screening may be part of the proposed work, but should not be the sole focus. Clinical components are permitted, but proposals should not center on clinical trials or medical device testing in humans.

MIND Prize winners each receive $250,000/year for three years, and they become part of a unique network of researchers associated with PSF. Generally, at least six prizes will be awarded annually. Benefits include:

• Facilitated partnerships with like-minded researchers within and across institutions
• Networking programs such as collaborations and discussions with industry mentors, introductions to philanthropic and for-profit investors in the business community, special industry networking and entrepreneurship events, and more
• An annual retreat
• Opportunities to present at conferences and events (hosted by PSF and other organizations)

Pershing Square Lotus Award for Ovarian Cancer Research

The Pershing Square Foundation (PSF) has worked across sectors to catalyze innovative approaches to the most difficult problems. Talented individuals have always been at the center of our approach. We aim to support leaders who transform systems, embrace new paradigms, and have an innate drive to make an impact.

PSF has funded pioneering cancer researchers through the Pershing Square Sohn Cancer Research Alliance for over a decade and supported women’s health initiatives in New York City. Through this Request for Proposals (RFP), PSF aims to combine these two priority areas of women’s health and cancer to shine a light on one of the most understudied and underfunded cancers—ovarian cancer. Ovarian cancer is the deadliest gynecologic cancer, with 80% of women diagnosed at an advanced stage. Only 27% of women diagnosed during an advanced stage survive for five years. Ovarian cancer remains a disease with a poor prognosis due to limited early detection and treatment options.

PSF supports research efforts by 

• deploying capital quickly, 
• funding high-risk, high-reward ideas, 
• bringing new perspectives into a field, 
• encouraging collaboration, and 
• leveraging our vast network. We challenge our scientific partners to think creatively and across silos, to spur innovation to fight ovarian cancer.

Through the Pershing Square Lotus Award for Ovarian Cancer Research, PSF is looking for investigators who are either already working on a promising project in ovarian cancer or in another type of cancer that could have an impact on ovarian cancer. Grantees each receive $250,000 a year for three years, totaling $750,000.

Researchers who are not studying ovarian cancer are encouraged to apply and required to find a collaborator with experience in ovarian cancer research.

This award aims to 

• inspire investigators with unique expertise to apply their knowledge to ovarian cancer and 
• empower ovarian cancer researchers to pursue their boldest, most innovative ideas. Facing a disease where too few have survived to-date, PSF ultimately aims to create a culture around ovarian cancer that offers women hope, akin to the breast cancer community. PSF is passionate about changing outcomes for tens of thousands of women a year and is hopeful that future scientific discoveries will allow for more survivors who can share their stories for years to come.

Disabled Veterans National Foundation

The Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability.

Guided by this commitment, DVNF developed its Health & Comfort programs, offering emergency financial assistance, housing transition support, food assistance, comfort kits, and wellness initiatives. These programs are designed to meet veterans where they are and to provide practical solutions that restore hope and stability. Today, DVNF continues to grow as a trusted national nonprofit. Every day, our team works with a clear purpose: to change lives for the men and women who have served our country.

Veterans Food Assistance Program

It is our goal to ensure that no veteran goes hungry by providing essential food assistance and household support, fostering stability and well-being in the lives of our veterans and their families.

The Veterans Food Assistance Program (VFAP) is designed to provide a one-time grant of essential food and household support to veterans and their families, ensuring no veteran goes hungry. With the rising cost of living, especially food prices due to inflation, this program offers a much-needed lifeline to those who have served our country. Once approved, the DVNF program team will handle the shopping for you.

The Veterans Food Assistance Program provides a one-time grant per household to support different family sizes, given the rising cost of food:

• Married Veterans Grant Allowance
  • Married - No Children up to $250
  • Married - 1 Child up to $300
  • Married - 2 Children up to $450
  • Married - 3+ Children up to $500
• Single Veterans Grant Allowance
  • Single - No Children up to $200
  • Single - 1 Child up to $300
  • Single - 2 Children up to $350
  • Single - 3+ Children up to $450

Virginia Economic Development Partnership

The Virginia Economic Development Partnership is the Commonwealth of Virginia’s official economic development authority and has offices in Virginia, Germany, Japan, Taiwan, and South Korea. Since 1995, VEDP has served as a professional, nonpartisan public authority with a long-term focus on strengthening Virginia’s economy across administrations. Working with state, regional and local partners, VEDP supports business expansion, attraction and investment through services that span site readiness, incentives, global trade and strategic planning. 

Virginia Investment Performance Grant

The Virginia Investment Performance Grant (VIP) encourages continued capital investment by existing Virginia companies, resulting in added capacity, modernization, increased productivity, or the creation, development, and utilization of advanced technology. The program targets existing manufacturers or research and development services supporting manufacturing. There must be an active and realistic competition between Virginia and another state or country for attracting the project, and matching local financial participation is expected.

The amount of each VIP grant is determined by the Secretary of Commerce and Trade, based in part on the Virginia Economic Development Partnership’s (VEDP) Return-on-Investment analysis and recommendation, and is subject to the approval of the Governor.

Highlights

Company must be an existing Virginia manufacturer or research and development service that supports manufacturing, and the project must result in capital investment of at least $25 million.

VIP grants are paid in five equal annual installments beginning in the first year after the capital investment and job creation or retention are achieved.

Virginia Economic Development Partnership

The Virginia Economic Development Partnership is the Commonwealth of Virginia’s official economic development authority and has offices in Virginia, Germany, Japan, Taiwan, and South Korea. Since 1995, VEDP has served as a professional, nonpartisan public authority with a long-term focus on strengthening Virginia’s economy across administrations. Working with state, regional and local partners, VEDP supports business expansion, attraction and investment through services that span site readiness, incentives, global trade and strategic planning. 

Virginia Economic Development Incentive Grant (VEDIG)

The Virginia Economic Development Incentive Grant program (VEDIG) assists and encourages companies to invest and create new employment opportunities by locating significant headquarters, administrative, or service sector operations in Virginia. There must be an active and realistic competition between Virginia and another state or country for attracting the project.

The amount of each VEDIG grant is determined by the Secretary of Commerce and Trade, based in part on the Virginia Economic Development Partnership’s (VEDP) Return-on-Investment analysis and recommendation, and is subject to the approval of the Governor.

Highlights

The program offers cash grants to qualified applicants. Grants are paid in five equal annual installments beginning in the first year after the capital investment and job creation or retention are achieved. There are no restrictions on expenditure of the grant proceeds.

Minimum capital investment, new job, and wage thresholds are based on the area of Virginia in which the company is located.

In collaboration with Cummins Inc., the American Library Association (ALA) invites applications from U.S. public libraries to participate in A Year of STEM, 12 months of curated STEM programming to foster curiosity and STEM-mindedness in early childhood learners across the country. 

Twenty-five libraries will be chosen to participate in A Year of STEM, receiving professional development to prepare them for the project, copies of a newly created A Year of STEM programming guide developed by librarian advisors, a $5,000 programming stipend, four STEM kits (to be delivered quarterly), and support from ALA’s Public Programs Office staff throughout the project implementation period.

LRPenn.com is home to the novels, plays, and screenplays of LR Penn. His books specializes in Thrillers, Dramatic Comedies, and Film Noir. Thanks to the generous support of our sponsors, grants may be available to nonprofit theater companies in the United States with 501(c)(3) status that are staging productions of plays written by LR Penn.