Best Alzheimer's and Dementia Research Grants in Texas

Brain Research & Innovation Network: Grant Initiative of Texas

The Rainwater Charitable Foundation is launching the Brain Research & Innovation Network: Grant Initiative of Texas (BRING IT), a new funding opportunity designed to support innovative ideas in brain health and dementia research across Texas.

BRING IT will provide one-year seed grants of up to $100,000 to Texas-based academic institutions and nonprofit organizations to accelerate promising research, foster collaboration, and generate the preliminary data and proof-of-concept evidence that can help seed a strong pipeline of innovative brain health and dementia research across Texas.

With the launch of DPRIT, Texas has a unique opportunity to expand its leadership in brain health and dementia research. BRING IT is designed to help seed and strengthen this growing research ecosystem by supporting innovative ideas, building collaborations, and generating early evidence that can help promising research move forward.

What We’re Looking For

RCF is seeking focused, innovative pilot projects that can advance brain health and dementia research while positioning promising ideas for future development and larger-scale funding.

Projects should be designed for completion within 12 months and generate a clear foundation for next-stage research, implementation, validation, or funding. Competitive proposals should address an important unmet need or research opportunity, demonstrate a strong and feasible approach, and show how the work could position the team for future DPRIT or other external funding.

BRING IT is particularly interested in projects that leverage Texas-based expertise, populations, institutions, healthcare systems, community organizations, datasets, infrastructure, or collaborations.

Areas of Interest

BRING IT will support projects aligned with five strategic topic areas reflecting anticipated DPRIT priorities and emerging opportunities in dementia research.

Support the translation of evidence-based innovations into real-world clinical and community settings. Areas of interest include brain and vascular health and dementia risk-reduction programs, blood-based biomarkers, AI-enabled clinical decision support, digital health technologies, community screening programs, care coordination models, and approaches that improve adoption in primary care, rural healthcare systems, and other medically underserved settings.

Projects should emphasize scalability and the potential to improve implementation of evidence-based brain health interventions, delay cognitive decline, promote timely diagnosis, reduce dementia risk, or enhance care.

Develop, validate, or apply New Approach Methodologies that improve the efficiency, predictive power, and translational relevance of dementia research.

Areas of interest include human iPSC-derived models, organoids, organ-on-chip systems, computational and AI-driven disease models, digital twins, neurovascular models, and other innovative platforms that can accelerate therapeutic discovery, biomarker development, or target validation.

Explore how digital health technologies and computational tools can help identify cognitive changes or risk factors within existing healthcare settings.

Projects may incorporate natural language processing, computer vision, clinical decision support systems, wearable sensors, speech analysis, retinal imaging, or other approaches that can be integrated into primary care and community health settings, particularly those serving rural and medically underserved populations.

Use machine learning and computational approaches to identify promising opportunities to repurpose existing regulatory-approved drugs for dementia and related neurodegenerative diseases.

Projects may explore disease-modifying or symptomatic treatment strategies and should establish a computational workflow that can provide a translational bridge to future validation studies.

Develop innovative approaches to identify and reduce dementia risk by addressing modifiable factors associated with cognitive decline.

Areas of interest include physical activity, nutrition, sleep, cardiovascular health, diabetes, obesity, hearing loss, and other modifiable risk factors. Projects may incorporate digital health technologies, wearable devices, AI, or community-based implementation approaches to improve brain health, reduce dementia risk, and support healthy aging across Texas populations.

The Isla Carroll Turner Friendship Trust Grant provides vital support for services to the elderly in Texas, focusing on individuals aged 60 and above, as well as those over 47 with Down Syndrome. Funding is restricted to nonprofits and governmental agencies within the state, enhancing educational programming and direct services. The Trust prioritizes local organizations to ensure effective management and delivery of resources for the elderly community.

BCBS of Texas provides sponsorships to organizations focused on improving community health and wellness. With awards ranging from $250 to $5,000, these sponsorships support various activities like health fairs, drives, and seminars. Organizations can apply for support but cannot receive both a grant and a sponsorship. Importantly, no 501(c)(3) status is required, making it accessible for diverse initiatives aimed at fostering healthier communities.

BrightFocus Foundation offers Alzheimer's Disease Research Grants to support innovative research aimed at understanding, preventing, and treating Alzheimer's disease. These grants encourage applications from diverse backgrounds, fostering creativity in scientific research. The program includes Standard Awards for early investigators with a maximum funding of $300,000 for three years and Postdoctoral Fellowship Awards for young researchers at $200,000 for two years, promoting the development of independent research careers.

The McKnight Brain Research Foundation Innovator Awards aim to support innovative research in cognitive aging and memory loss, offering two 3-year grants of $750,000 each. Targeted at early-career investigators, the program encourages high-risk, high-gain proposals that explore clinical translational research and the biological mechanisms of cognitive aging. By fostering emerging scientific leaders, the initiative seeks to advance transformative discoveries in this critical area of aging research, enhancing understanding and treatment of age-related cognitive decline.

The JTMF Foundation Grant focuses on improving the lives of individuals in need, particularly in the Pacific Northwest. By partnering with organizations addressing immediate needs and long-term challenges, the foundation supports children, older adults, veterans, and individuals with intellectual and developmental disabilities. Guided by Catholic values, JTMF aims to empower communities while seeking innovative solutions to societal issues. Organizations that align with these focus areas are encouraged to connect, fostering a collaborative effort towards meaningful impact.

The Alzheimer’s Foundation of America Bi-Annual Grant aims to support nonprofit organizations in their efforts to enhance the lives of individuals impacted by Alzheimer’s disease and related dementias. Each grant, valued at $6,000, is awarded twice a year, focusing on innovative programs and services. AFA emphasizes partnership and collaboration, enabling grantees to manage their own policies and programs while adhering to specific funding guidelines. This initiative underscores AFA's commitment to compassionate care and ethical standards.

The NIA Expanding Research in AD/ADRD Postbaccalaureate Research Education Program aims to enhance the research workforce by providing intensive research experiences for recent graduates. This initiative supports early-stage investigators in Alzheimer's Disease and related dementias, addressing a critical shortage of researchers in the field. Participants engage in independent research, mentorship, and professional development, equipping them with skills necessary for advanced degrees and research careers in aging and dementia. The program fosters innovation and interdisciplinary collaboration essential for advancing AD/ADRD research.

The NIA Expanding Research in AD/ADRD Summer Research Education Program supports the recruitment of early-stage investigators and aims to provide hands-on research experiences in Alzheimer's Disease and related dementias. Targeting high school students, undergraduates, and science teachers, the program enhances STEM education through authentic research opportunities and educational activities. By fostering early exposure to research, it aims to stimulate interest in AD/ADRD careers and address workforce shortages in this critical field.

The Alzheimer’s Association Research Grant For All (AARGA) Program supports early-career investigators in their first seven years as independent researchers. This grant aims to fund projects that develop preliminary data and test new hypotheses in Alzheimer’s and related dementia research. Areas of interest include disease mechanisms, biomarker development, and health equity. Applications are welcome from both U.S. and international researchers, fostering innovation and collaboration in the fight against dementia.

The Dementia Care and Brain Degenerative Diseases Grant, offered by the Sephardic Home For The Aged Foundation, aims to support innovative projects enhancing care and quality of life for older adults affected by dementia. Eligible organizations must be 501(c)3 nonprofits in operation for at least two years. The Foundation prioritizes proposals focusing on dementia care, promoting collaboration and resource access for aging individuals. Interested applicants should submit a Letter of Inquiry through the online application system.

The Alzheimer’s Association Research Fellowship for All (AARFA) Program aims to support early career researchers dedicated to advancing the understanding and treatment of Alzheimer’s and other dementias. By providing funding to postdoctoral researchers under established mentorship, the program fosters the development of independent scientists. It encourages applications from individuals in underrepresented groups, recognizing the value of diverse perspectives in scientific inquiry and clinical practice, ultimately contributing to the fight against dementia.

The Alzheimer’s Association Clinician Scientist Fellowship for All (AACSFA) aims to support the training of clinician scientists in Alzheimer’s and other dementias. This program encourages applications from individuals in underrepresented groups, emphasizing the value of diverse representation in clinical and scientific fields. The fellowship is designed for professionals with patient contact or diagnostic roles, fostering advancements in dementia research and care.

The Anne & Irving Brodsky Innovation Grant, offered by the Alzheimer's Foundation of America, provides $25,000 to support innovative programs that enhance the lives of individuals affected by Alzheimer's disease and related conditions. This grant is exclusively available to AFA nonprofit member organizations, with funding directed towards essential program expenses such as staff training, administrative costs, and necessary supplies. The initiative aims to foster advancements in care and support for families dealing with Alzheimer's.

The Project Lifesaver International Grant by the Alzheimer’s Foundation of America aims to fund programs that prevent wandering and enhance public safety for individuals with dementia-related illnesses. This grant supports public safety agencies that are members of AFA and Project Lifesaver International, focusing on essential training, supplies, and community outreach. Grants are awarded biannually, promoting better care and safety for individuals living with Alzheimer’s disease and related dementias.

The Milton & Phyllis Berg Family Respite Care Grants, offered by the Alzheimer’s Foundation of America, support member organizations in providing respite care scholarships to families affected by Alzheimer's. This initiative enhances the quality of life for both individuals and caregivers by promoting social engagement and offering essential breaks for caregivers. Grants are awarded biannually in memory of Barry E. Berg's parents, who faced Alzheimer's and caregiving challenges.

The Alzheimer’s Association and ASNR Imaging Research Grant focuses on advancing imaging research in Alzheimer’s and other neurodegenerative diseases. This partnership aims to support early-stage pilot projects that develop novel imaging tools and innovative data analysis methods. Up to three proposals will be funded, with each award capped at $200,000 for one year, promoting significant advancements in the field and enhancing research capabilities for better understanding of dementia.

Margaret B. Moeller Memorial Fund for Alzheimer's Home Care Companions

Grants support families in the Boyertown Area School District with members who suffer from Alzheimer's disease or other types of dementia.

The Margaret B. Moeller Fund for Alzheimer's Home Care Companions provides grants for families in the Boyertown Area School District with individuals who suffer from Alzheimer's disease or other types of dementia to obtain the services of in-home care companions, aides or other providers of respite care. Grants generally pay for several days of care for a specified period of time. The fund was created to help families who are not eligible for any other form of reimbursement for such services. Decisions are generally made within 15 days of receiving a complete application, including the referral.

The National Institute of Neurological Disorders and Stroke (NINDS) aims to support innovative research for validating therapeutic targets in Alzheimer's Disease-Related Dementias (ADRD). This initiative focuses on overcoming barriers in treatment development by ensuring well-validated targets linked to disease mechanisms. By employing a phased award mechanism, NINDS seeks to enhance the rigor of target validation, facilitating the transition from basic discoveries to clinical applications, ultimately accelerating the development of effective therapeutic strategies.

Health Services Research in Alzheimer’s Disease and Related Disorders (HSR-ADRD) Program

The HSR-ADRD program seeks to support research that strengthens dementia detection, diagnosis, and post-diagnostic care pathways along the care continuum. Projects may address a range of health services research questions, including, but not limited to, studies examining barriers and solutions to timely access, quality, and care coordination. By supporting rigorous and innovative research, this program aims to generate actionable evidence to improve person-centered, coordinated, and equitable brain health and dementia care.

Program overview

The program welcomes proposals that utilize rigorous methodologies to advance understanding and improvement of cognitive impairment, including MCI and Alzheimer’s disease and related dementias (AD/ADRD) detection, diagnosis, and post-diagnostic care.

This award is structured as an individual research grant, with funding administered through the recipient’s institution. Proposals should address one or more Areas of Focus. Areas of Focus represent high-priority research topics for which this program is actively seeking proposals and include: 

• The Value of Early Detection and Diagnosis: Studies should investigate outcomes associated with early detection and diagnosis on at least two levels of the dementia care ecosystem (i.e., individual/families, providers/clinicians, health systems/payers, and policy/society).
• Care Pathways for Individuals with MCI or Dementia: Studies should consider comorbidities and investigate how people are being screened and diagnosed in different settings, and the post-diagnosis pathways for care and treatment, including pharmacological and non-pharmacological interventions or combinations thereof.

Funding overview

• Each HSR-ADRD award is limited to a total of $250,000 U.S. (direct and indirect costs) for a duration of up to two years (awards should be a minimum one year).
• Indirect costs are capped at 10 percent of total direct costs and are inclusive of indirect costs for the implementing institution as well as for any subcontracts.

The NIH Blueprint for Neuroscience Research Network aims to enhance foundational research on human consciousness, addressing critical biomedical issues such as coma and dementia. By fostering a collaborative framework among 14 NIH institutes, the initiative seeks to improve diagnosis and treatment of neurological disorders through interdisciplinary approaches. Key objectives include detecting consciousness in minimally responsive patients, enhancing understanding of sleep disorders, and exploring new methodologies. This effort will ultimately strengthen U.S. leadership in neuroscience and improve patient outcomes.

The NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) aims to create a secure, scalable cloud platform for genetic data related to Alzheimer’s disease. This initiative will enhance data accessibility, promote interoperability, and support rigorous research practices. By facilitating collaboration and providing robust analytical tools, the platform will maximize the scientific impact of AD/ADRD research, aligning with NIH goals for transparent and reproducible science, while addressing recommendations for broad access to high-value datasets.

The National Institute on Aging (NIA) is inviting applications for the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional). This initiative seeks to support pre-clinical and early-stage clinical development of innovative drug candidates aimed at preventing Alzheimer's disease or treating its symptoms. The program encourages collaboration among researchers and aims to enhance the therapeutic pipeline for AD through targeted approaches. This notice allows potential applicants time to prepare robust projects.

The Alzheimer's Disease Programs Initiative (ADPI) aims to foster the development of dementia-capable community health worker programs within the National Aging Network. This initiative, supported by the US HHS: Administration for Community Living (ACL), seeks to enhance dementia screening, reduce barriers to care, and improve access to essential services for individuals with dementia and their caregivers. By integrating community health workers into aging services, the program aspires to elevate the quality of life for those affected.

The Barney Family Foundation Grant focuses on improving early education and advancing medical research, particularly in cancer and Alzheimer’s. It supports organizations that demonstrate a clear plan to enhance children's life experiences and educational opportunities for those in grades K-8. Grants typically range from $5,000 to $50,000, prioritizing established entities while welcoming startups. Eligible applicants must have 501(c)(3) status, and the Foundation does not fund individual requests or political activities.