Best Addiction and Substance Abuse Grants in California

California Commission for Behavioral Health

Proposition 63, approved by California voters in 2004, created the Mental Health Services Oversight and Accountability Commission to drive transformational change across the state’s mental health system.

The Commission oversees the implementation of the far-reaching initiative, which imposed a 1 percent income tax on wealthy residents to pay for mental health services and established a framework for continuous improvement of mental healthcare in the state.

Partnering with public and private mental health agencies at all levels, the Commission works to ensure that people get the care they need in a timely, comprehensive, effective, and culturally competent manner. In everything, it vigorously promotes community collaboration.

Innovation Partnership Fund (IPF) Request for Application (RFA)

The Commission for Behavioral Health (CBH) is thrilled to announce the official release of the Innovation Partnership Fund (IPF) Request for Application (RFA), marking the first round of a significant multi-year investment. This initiative, established through the Behavioral Health Services Act (BHSA), aims to award up to $20 million in grants this year to drive bold, equity-centered innovations within California’s public behavioral health system.

This groundbreaking fund is designed to invest in solutions that will fundamentally improve how mental health and substance use disorder services are delivered, experienced, and sustained across the state, with a strong focus on supporting county behavioral health departments. This RFA was built upon extensive community and system partner feedback ensuring that the initiatives supported reflect the real-world needs of Californians. It was also developed in collaboration with the California Health & Human Services Agency, the California Department of Health Care Services, the California Department of Public Health, and the California Department of Health Care Access and Information.

This first round of IPF offers two distinct grant categories, each with specific eligibility requirements: Category 1 – Small Grants; and Category 2 – Large Grants.

Category 1 – Small Grants

Grant awards of less than $500,000.

A minimum of 8 grants will be awarded, with a total of $4 million available. These grants are exclusively open to community-based organizations, non-profit entities, and/or tribal organizations.

Key Application Requirements

To be considered for this fund, applicants’ proposed solutions must:

• Be innovative by advancing new or scaled culturally competent models, practical community-centered solutions, demonstrating a clear break from the status quo, or being ready for real-world implementation;
• Address the needs of BHSA Priority Populations, including underserved, low-income, and communities impacted by other behavioral health disparities;
• Apply to and support county behavioral health programs, either directly or indirectly; and
• Address key Cross-Cutting Elements, including Equity, Financial Sustainability, Lived Experience and Community Leadership, Alignment with Statewide Transformation Efforts, and Agility/Quality Improvement Integration.

California Department of Public Health

The California Department of Public Health (CDPH) works to protect the public’s health and shape positive health outcomes for individuals, families and communities. Public health is for everyone; not just in emergencies but in everyday life — from heart health and mental wellness to food safety and the prevention of infectious and chronic diseases. Our programs and services, in collaboration with local health departments, state, federal and private partners, touch the lives of every Californian and visitor, 24 hours a day, 7 days a week.

The California Tobacco Control Branch

The California Tobacco Control Branch leads statewide and local health programs, services and activities that promote an environment truly free of tobacco. ​

Statewide Priority Population Coordinating Center 

Purpose

This Request for Application (RFA) seeks to fund one (1) Statewide Priority Population Coordinating Center (PPCC), to coordinate and foster interactive and integrative collaboration and communication among California Department of Public Health, California Tobacco Prevention Program (CDPH/CTPP)-funded projects, as well as other state, regional, and local partners to address tobacco-related disparities. The PPCC will focus on each of the following population groups starting July 1, 2026: 1) African American/Black; 2) Asian American/Native Hawaiian/Pacific Islander (AANHPI); 3) Latino; 4) Lesbian, Gay, Bisexual, Transgender, Queer or Questioning (LGBTQ+); 5) Rural communities. Starting July 1, 2027, the PPCC will also incorporate collaboration and communication with American Indian and Alaska Native populations.

About CommonSpirit

A calling that defines and unites

At CommonSpirit Health, we passionately care for the most vulnerable, relentlessly innovate how and where healing can happen and believe in uniting to benefit the common good. Our expansive network spans diverse communities, uniquely positioning us to meet their changing needs, improve population health and help chart the path to health equity.

Our mission, vision and values inform every aspect of our work each day and remind us that we serve our patients, their families, our communities – and each other. Our community health, research and home health programs help us address the primary barriers to healthier communities.

Sponsorship requests

We’re proud to support nonprofits that expand access to care, advance health equity and healthier communities. Learn more about our priorities.

Supporting our communities

CommonSpirit Health and our local facilities support nonprofit organizations that share our mission, vision and values. We give priority to programs that improve access to care and promote health equity and healthier communities.

CommonSpirit is proud to support nonprofit organizations that help improve the health and well-being of our communities. Guided by our mission, vision and values, we prioritize projects that focus on advancing health equity, improving access to care and improving community wellness.

About Elevate Youth California (EYC)EYC is grounded in social justice youth development (SJYD), which expands the concept of a positive youth development framework and addresses social factors including racism, xenophobia, and other racial inequities youth face as they develop into adulthood. Through a public health and harm reduction lens, EYC supports culturally and linguistically responsive, healing-centered, and trauma-informed strategies that prevent substance use before it begins, particularly in communities disproportionately harmed by the war on drugs. Youth Substance Use Disorder Prevention: Standard Track Cohort 8The required goal of this funding opportunity is to address SUD prevention by investing in youth

leadership and civic engagement for youth of color and 2S/LGBTQIA+ youth ages 12 to 26 living in communities disproportionately impacted by the war on drugs. California Department of Health Care Services is seeking applications that: 

• Support youth engagement that focuses on youth civic engagement, specifically in communities disproportionately impacted by the war on drugs.
• Possess cultural humility and responsiveness with staff and organizational leadership who reflect the racial, ethnic, and cultural community they intend to serve.
• Prioritize public health solutions that focus on positive messages to prevent SUD.
• Develop culturally responsive and linguistically appropriate social justice youth development, peerto-peer support, and mentoring programs that are healing-centered, trauma-informed, and focused on youth ages 12 to 26.
• Utilize an intersectional approach to health equity through policy, systems, and environmental change.
• Implement SUD prevention activities that address the root causes of SUD, reduce risk factors, and increase protective factors. 

The Youth Community Access Grant Program, introduced by the California Natural Resources Agency, aims to enhance outdoor access for youth, particularly in low-income and disadvantaged communities. Funded by the Youth Education, Prevention, Early Intervention and Treatment Account, this program supports initiatives like community education and recreational amenities for substance use prevention. With approximately $18.5 million available, grants range from $25,000 to $500,000 to foster a healthier, more inclusive California.

The Slave 2 Nothing Foundation supports 501(c)(3) organizations addressing human trafficking and substance abuse in states with In-N-Out Burger locations. Their mission is to empower individuals to overcome enslavement by providing essential resources and support. The foundation follows a rigorous vetting process for grant applications, emphasizing the importance of impactful solutions and community engagement. They encourage eligible nonprofits to apply annually, promoting sustainable support for vital services aimed at healing and freedom.

The Transition Age Youth Advocacy Grant aims to empower young individuals aged 16-25, particularly those with serious mental health challenges, to advocate for their needs within California's behavioral health system. By fostering leadership and engagement, this initiative seeks to involve these youth in meaningful advocacy efforts that address issues like homelessness and involvement in justice systems. The goal is to create a supportive environment that reflects their realities and promotes their agency.

The Charis Fund Grant supports non-profit organizations in California, Oregon, Washington, and Nevada, focusing on social welfare, health, and education. Grants range from $2,500 to $7,500, aimed at addressing issues such as housing, food insecurity, and support for at-risk youth. Eligible organizations must be 501(c)(3) certified and can apply every three years, with specific restrictions on funding for arts and political activities.

Funding Opportunity: Opioid and Stimulant Use Disorder Prevention and Education

The California Department of Health Care Services, in partnership with The Center at Sierra Health Foundation, is announcing a new funding opportunity, Opioid and Stimulant Use Disorder Prevention and Education. This opportunity offers a 12-month contract for up to $200,000.00. Contracts will run from September 1, 2026 – August 31, 2027.

Funding is available for organizations to implement programs addressing opioid use, stimulant use, and polysubstance use in California. Activities should support awareness, prevention, outreach and education, work to decrease community stigma, and strengthen referral pathways to treatment and medications for opioid use disorder. Activities must be inclusive to all who seek services. Please note that the opportunity will not fund direct treatment activities or recovery support services.

The Elevance Health Foundation's Behavioral Health Grant aims to address significant challenges in mental health and substance use disorders. With a commitment of up to $90 million over three years, the Foundation seeks partnerships with nonprofits to enhance treatment access, promote prevention strategies, and alleviate loneliness among affected individuals. This initiative emphasizes innovative solutions and measurable outcomes, targeting both national and local programs, particularly in states with pressing health disparities.

The Dermody Properties Foundation Grant focuses on enhancing community well-being through support for the arts, education, and families, particularly children and the elderly. Established in 1988, the foundation has provided over $3.65 million in donations to various nonprofits, including grants and scholarships. Eligible organizations must have IRS 501(c)(3) status and be located within 30 miles of Dermody's projects. Grants typically range from $500 to $3,000, reflecting a commitment to corporate philanthropy.