Best Large Grants for Nonprofit Organizations in California

The Mission Program Grants: New Worshiping Communities Seed Grant offers up to $10,000 to support the establishment of new worshiping communities connected to the Presbyterian Church (USA). These grants focus on covering initial operational costs for the first year, including salaries and educational materials. Eligible applicants must be newly formed communities established after July 2010, located in the U.S. or Puerto Rico. This initiative fosters community growth rather than expanding existing congregations.

The NCI Pathway to Independence Award (K99/R00) supports talented postdoctoral researchers in transitioning to independent faculty positions. This program provides essential NCI research funding to facilitate the development of competitive, independent research careers. Applications are due by 5:00 PM local time of the applicant's organization, emphasizing the importance of timely submissions for prospective awardees.

The National Cancer Institute (NCI) invites applications for innovative technologies aimed at cancer research and clinical care. This funding opportunity supports early-stage projects focused on proof-of-concept studies to assess the feasibility of new methods and tools. Applications should demonstrate significant technical innovation, targeting advancements in cancer biology, early detection, clinical diagnosis, treatment, and epidemiology. Technologies may include novel analysis platforms, imaging technologies, and biospecimen processing innovations, with a focus on cancer applications.

The Academic Research Enhancement Award (AREA) supports small-scale research at institutions that receive limited NIH funding, emphasizing biomedical research for undergraduate students. This program aims to enhance the research environment and provide valuable experiences for students. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over four of the last seven years. This funding opportunity encourages investigator-initiated minimal risk clinical trials to advance NIH missions.

The Shared Instrumentation Grant (SIG) Program supports NIH-funded investigators in acquiring high-cost, specialized instruments, with a minimum award of $50,000 and a maximum of $750,000. Eligible instruments include light microscopes, mass spectrometers, and DNA sequencers, among others. This program aims to enhance research capabilities by enabling the purchase or upgrade of essential equipment for scientific advancement.

About The Community Foundation of Hancock County

We are a nonprofit, public charity that encourages philanthropy, convenes and leads community initiatives, provides educational support, and supports nonprofit organizations. 

Scholarships for Adults & Non-Traditional Students

The Community Foundation of Hancock County offers educational support for Hancock County, Indiana adults who are seeking post-secondary training or schooling to improve their career prospects. There are also some opportunities provided by specific businesses in the area. 

William W. Weil Good Citizen Scholarship

William W. Weil was born and raised in Greenfield, Indiana. After serving in the Korean War as an Aviation Engineer, he returned to Greenfield and became a respected local businessman as manager of the Broadway Lumber Company and the Weil Theatre. Bill was best known as a member of the Greenfield Banking Company Board of Directors for over 53 years. This scholarship was established to reward good citizenship.

Bold Foundation

Our Mission: Fighting Student Debt

The average student today will graduate more than $30,000 in debt and is far less likely to start small businesses, seek the highest impact careers, buy homes, or start families. At Bold.org®, we believe that’s a problem worth solving.

New Beginnings Immigrant Scholarship

Immigrating to a new home takes resilience, determination, and a strong commitment to achieving one’s aspirations.

Many immigrants have overcome extraordinary challenges and obstacles to continue their academic journeys and pursue their dreams. As a result of these hurdles, many students from immigrant backgrounds have limited financial resources which can make higher education inaccessible.

This scholarship seeks to support immigrant students so they can continue working toward their educational goals.

To apply, tell us about your experience as an immigrant and your career aspirations.

Biochemical and Molecular Characterization of Marstacimab and TFPI Pathways

This competitive grant encompasses research aimed at elucidating molecular and cellular mechanisms underlying marstacimab-TFPI interactions, including but not limited to differential expression of tissue factor and TFPI in various tissues, binding kinetics, and other biochemical properties. Projects should seek to advance foundational understanding of these interactions through innovative approaches in biochemistry, molecular biology, and related disciplines.

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

The BMC Expedition Grant supports British climbers for international expeditions, prioritizing those who have been BMC members for at least two years. Grants are aimed at younger climbers and under-represented groups, promoting sustainable practices in expedition planning. Eligible teams must demonstrate a commitment to climbing and innovative objectives, while ineligible projects include commercial expeditions and those failing to adhere to grant conditions. This funding aims to foster significant personal development and environmentally conscious climbing.

Who We Are

Thousands of your friends and neighbors make up Samaritan Health Services. We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of your ability to pay.

Linn County- Samaritan Lebanon Community Hospital Auxiliary Scholarship

East Linn County students currently attending college and majoring in a medical field are invited to apply for the Samaritan Lebanon Community Hospital $1,000 Auxiliary Scholarship.

Community Foundation of the Central Blue Ridge

The Community Foundation of the Central Blue Ridge is a charitable organization that has served the independent cities of Staunton and Waynesboro, and the counties of Augusta, Highland and Nelson since 1992. 

Martin Lightsey Scholarship for Technical Education

The Martin Lightsey Scholarship for Technical Education was established to honor Martin Lightsey and all he achieved in the creation and subsequent success of Specialty Blades, Inc. (Cadence, Inc.), upon his stepping down as CEO of the company in 2002.

Description

The Martin Lightsey Scholarship for Technical Education was established in 2002 to provide funds for college scholarships to seniors residing in Staunton, Waynesboro and Augusta County, who intend to pursue or are currently pursuing technical education at a two-year or four-year college. Examples of technical education include but are not limited to degrees in engineering, math, chemistry, physics, computer sciences, statistics, and architecture and associate studies in areas such as quality control, process technology, manufacturing technology, machining, electrical and mechanical operations, and information technology.

Cadence, Inc. and the honoree of this scholarship, Martin Lightsey, value the many possible choices in the pursuit of technical education and careers. Many professional roles in the manufacturing sector require highly-specialized training, much of which can be obtained through community colleges. As such, Cadence Inc. and Mr. Lightsey welcome scholarship applications from students pursuing specific industry credentials, associate degrees, and bachelor degrees.

Selection Criteria Used by the Selection Committee

• Academic Merit
• Financial need
• Community service activities
• Leadership ability

The Radiation Oncology-Biology Integration Network (ROBIN) Centers, funded by the National Cancer Institute (NCI), aims to enhance national radiation oncology infrastructure through collaborative research. This initiative supports studies on biological responses to radiation treatment in cancer patients, focusing on understanding tumor and tissue changes. By integrating various scientific disciplines and collecting comprehensive data, ROBIN intends to improve cancer care, optimize treatment strategies, and accelerate translational discoveries to enhance patient outcomes.

The NHGRI's Analysis, Visualization, and Informatics Lab-space (AnVIL) program is set for a limited competition renewal to enhance a cloud-based platform that supports genomic research. With over 5 petabytes of data accessible to researchers, AnVIL fosters collaboration and innovation while adhering to FAIR principles. The renewed focus will include improved scalability, interoperability, and robust security measures. Additionally, training initiatives will ensure researchers maximize the potential of AnVIL's multimodal datasets. The funding opportunity is expected in 2027.

About

Who We Are

For over 25 years, the Wichita Falls Area Community Foundation has remained committed to leaving a legacy for future generations by promoting philanthropy, providing charitable opportunities, and facilitating donors’ interests. You can trust us to offer expertise in local nonprofit needs and best practices for charitable giving while ensuring your giving goals are met.

Scholarship Opportunities

Royal C. “Bingo” Kinder Scholarship Endowment

The Royal C. "Bingo" Kinder Scholarship Fund was created in 2003 after the passing of Bingo Kinder in 2002. In his will, Mr. Kinder left instructions that portions of his estate be used to support scholarships for the students of Archer County, as well as local grants for Archer County nonprofits. Mr. Kinder graduated from ACHS in 1932 and had a successful track and field career before graduating from the University of North Texas in 1938. Mr. Kinder was a U.S. Navy veteran, a member of the Archer City School Board for 6 years, and a member of the Archer Livestock Association, among others.

The Grow Wild Grant Program, offered by the National Wilderness Stewardship Alliance, aims to establish a wilderness stewardship group for every Wilderness area in the National Wilderness Preservation System. This initiative supports start-up groups and existing organizations seeking to expand their impact. Funded by The David Berolzheimer Foundation, it honors Elaine Dermody, a dedicated wilderness champion. Eligible applicants include IRS-recognized nonprofits and those with qualified fiscal sponsors.

The USPOULTRY Research Grants program, sponsored by the U.S. Poultry and Egg Association, aims to enhance the poultry industry through comprehensive research funding. Established in 1963, it supports diverse projects related to poultry and egg production. With over $30 million invested, the program emphasizes improving product quality and safety. Proposals are evaluated by a panel of experts, with a funding rate of 15-20%. Eligible projects typically have budgets under $80,000 and timelines of 1-2 years.

The USF Community Impact Grant, established by USA Swimming and the USA Swimming Foundation, aims to enhance competitive opportunities in swimming clubs. Grants of up to $5,000 are available for registered USA Swimming clubs committed to fostering community engagement and collaboration. Eligible clubs can renew their grant for up to three years, promoting diverse access to swimming programs. This initiative particularly supports clubs that partner with educational or public entities and those led by women or minorities.

The International Fellowship, offered by the American Respiratory Care Foundation, supports healthcare professionals from abroad to enhance their expertise in respiratory care. Participants will engage in site visits across the U.S., observing practices in hospitals and educational institutions, while attending the AARC Congress. This fellowship covers travel expenses, lodging, and food allowances, promoting global collaboration and knowledge exchange in respiratory health.

The Adult Learn-to-Swim Grants, offered by the USA Swimming Foundation in collaboration with U.S. Masters Swimming, aim to enhance swimming safety for adults aged 18 and over. This initiative provides funding to programs that promote swim education, targeting underserved communities. Grants can be used for expenses like pool rentals and scholarships, with a maximum award of $5,000. The goal is to reduce drowning risks and encourage ongoing participation in swimming activities.

The Smallwood Young Investigator Fellowship, established in memory of Craig Smallwood, PhD, RRT, supports emerging researchers in pediatric respiratory therapy. It provides funding up to $5,000 to help candidates gain mentorship, hands-on experience, and essential resources to launch their research projects. Ideal applicants are members of the American Association for Respiratory Care, either at the thesis phase of their education or recently graduated. This initiative aims to foster growth in the field of respiratory health.

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

• Gives grants, scholarships, and organizational support to address the needs of our community.
• Builds a permanent endowment to help our donors create a legacy through this endowment.
• Promotes informed philanthropy to increase and sustain charitable resources for the region.
• Provides leadership and builds partnerships to identify and solve community issues.

Gary and Janet (Bell) Pettengill Scholarship

Gary approached the Community Foundation after the unexpected death of his wife, Janet, or AJ as she was known by her nieces. For those who knew Janet, she had the heartiest laugh, enjoyed life to the fullest and when she loved you, she loved you with all of her heart.

Scholarship Details

• Available to High School Seniors
• Nonrenewable

All ACCF Scholarships are merit based.

The America’s Horse Cares Grant Program, provided by the American Quarter Horse Association, aims to enhance the welfare and training of American Quarter Horses in therapeutic settings. By funding educational workshops from March to September 2026, the program seeks to elevate horsemanship standards and ensure proper horse care. Organizations eligible for funding must be 501(c)(3) tax-exempt, focusing on equine-assisted activities for individuals with various challenges, thereby fostering transformative experiences through education and responsible practices.

The Jerome M. Sullivan Research Fund, established by the American Respiratory Care Foundation, aims to promote original research in respiratory care. Grants, typically up to $10,000, are available for projects involving respiratory therapists or technicians. The fund supports both applied clinical and basic research in respiratory care and cardiopulmonary medicine, fostering advancements in the field. This initiative aligns with the foundation's mission to enhance respiratory health through research and education.

The Magistro Family Foundation Research Grant, offered by the Foundation for Physical Therapy Research, aims to enhance health through physical therapy research. With a commitment to funding innovative projects, this grant provides $200,000 for one or two years to support emerging and established researchers. The foundation focuses on addressing health disparities and advancing evidence-based practices in physical therapy, ultimately improving the quality of life for diverse communities.

The Parker B. Francis Respiratory Research Grant, offered by the American Respiratory Care Foundation, aims to support innovative research in respiratory care. Grants are available to qualified investigators, with a focus on projects involving respiratory therapists or technicians. Awards typically do not exceed $10,000 annually and are intended to supplement other funding sources. This initiative underscores the foundation's commitment to enhancing respiratory health through research and education.

The J. Thomas Dutro Jr. Student Award, presented by the Paleontological Research Institution, recognizes the significance of systematic research in paleontology. This $500 award is open to graduate students (Masters or Ph.D.) engaged in systematic paleontology research. Eligible expenses include research supplies, bench fees, and travel for fieldwork or conferences, supporting the academic growth of promising paleontologists.

The Foundation for Physical Therapy Research aims to enhance public health through funding innovative research in physical therapy. With a mission to optimize movement and improve societal health, it supports both emerging and established researchers. By offering grants, scholarships, and fellowships, the Foundation has created a robust pipeline of skilled researchers. Their efforts also focus on addressing health disparities and advancing evidence-based practices, ensuring a brighter future for the profession and its impact on patient care.