Upcoming Webinar
Instrumentl Fall Launch: Grant Work, Leveled Up.
Thu, Oct 29 or Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best Large Grants for Nonprofit Organizations in California

Find the perfect Large Grants for Nonprofit Organizations in California on Instrumentl. 11,000+ Large Grants for Nonprofit Organizations in California in the United States.

11,000+

Available grants

$4.24B

Total funding

$5K

Median grant

11,000+ grants
$4.24B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

10,611 Results based on applied filters

Veteran Grant

The Hanger Charitable Foundation
Corporate
United States
Up to US $20,000
The Hanger Foundation's Veteran Grant aims to empower veterans facing physical challenges by providing support for rehabilitation services and athletic programs. This grant seeks to positively impact veterans' lives, particularly those with limb differences, through community engagement and employee involvement in charitable efforts. With a focus on 501(c)(3) organizations, the foundation invests in projects that address trauma and promote social activities, ensuring that veterans receive the assistance they need.
Military & Veterans Services Medical Rehabilitation

Edwards Lifesciences Foundation Grants

Edwards Lifesciences Foundation
Private
United States
Unspecified amount
The Edwards Lifesciences Foundation Grants program aims to improve the health of underserved communities by supporting initiatives focused on education, screening, and treatment of cardiovascular disease. The Foundation seeks to enhance care access for patients, promote awareness of heart health, and foster community engagement through volunteer opportunities. By 2025, the goal is to positively impact the lives of 2.5 million patients affected by structural heart issues. The program emphasizes collaboration and innovation in healthcare.
Cardiovascular Diseases & Systems

OREF Prevention of Musculoskeletal Youth Sports Injuries Research Grant

Orthopaedic Research and Education Foundation
Private
Canada, United States
US $25,000
The Prevention of Musculoskeletal Youth Sports Injuries Grant provides essential funding for new investigators focused on clinical and social research aimed at reducing youth sports injuries. This initiative emphasizes the importance of clinical relevance in project proposals, ensuring that outcomes are practical and applicable. Only one grant will be awarded per institution each year, supporting innovative approaches to enhance youth sports safety and health.
Orthopedics Children’s Health & Pediatrics

High-Achieving Four-Year Scholarship

Coral Gables Community Foundation
Private
United States
Up to US $10,000

Coral Gables Community Foundation

Led by community leaders, the Coral Gables Community Foundation provides the philanthropic conduit to connect individuals and corporations looking to positively impact the success of the community. Now in its 33rd year, the Foundation has been at the forefront of the evolving needs of Coral Gables while effectively bringing together beneficiaries and benefactors to fund programs with the greatest impact and benefit to “The City Beautiful.”

Coral Gables Community Foundation’s Scholarships Program

Coral Gables Community Foundation is honored to partner with our fundholders to administer generous scholarships as well as manage the Foundation’s own scholarship funds.

The Foundation and its fundholders have proudly awarded over $6.7 million in scholarships in just the last decade.

High-Achieving Four-Year Scholarship

This 4-year scholarship is given annually to students who have demonstrated overall academic achievement and dedication to service within the school and in his/her community, and have low family income. The Foundation also considers applicants’ motivation, financial need, and personal experiences.

Maintenance

In order to maintain the scholarship each year, the recipient must maintain a minimum overall 3.0 GPA throughout his/her college studies.

Education - Higher Education Vocational & Trade Education

Robert Lehman Foundation Grant

Robert Lehman Foundation
Private
United States
Unspecified amount
The Robert Lehman Foundation Grant supports visual arts initiatives, including exhibitions, art education programs, scholarly publications, and lectureships. It aims to enhance the role of visual arts in culture, particularly for underserved communities lacking access to art education. The Foundation also funds capital projects that advance cultural programming and broaden audience engagement. By promoting these endeavors, the Foundation seeks to improve lives through artistic access and education.
Visual Arts Art History

Finra Foundation: General Grant Program

Finra Investor Education Foundation
Private
United States
US $50,000 - US $100,000
The FINRA Investor Education Foundation's General Grant Program funds educational and research projects aimed at enhancing financial literacy among underserved populations. Grants ranging from $50,000 to $100,000 support initiatives that promote financial inclusion and address systemic inequities. The foundation prioritizes projects that utilize existing data to improve understanding of financial capability and well-being. Applications are accepted anytime, with a focus on sustainability beyond the grant period.
Financial Literacy

Petfinder Emergency Medical Grant

Petfinder Foundation
Private
Canada, United States
US $100 - US $1,000
The Petfinder Emergency Medical Grant assists Petfinder members in providing urgent medical care for pets in need. Grants range from $100 to $1,000 and are awarded monthly until funds are depleted. Eligible expenses cover various emergency treatments, with a focus on saving one pet's life or improving its quality of life. Applicants must be active Petfinder members and agree to share their stories on social media, promoting both the grant and the pets they help.
Veterinary Science & Services Animal Welfare - Domestic Animals & Pets

FWW Fellowship Award

Foundation for Womens Wellness Inc.
Private
United States
Up to US $5,000
The FWW Fellowship Award supports emerging physicians and scientists dedicated to advancing women’s health research. Awardees, pursuing MD or PhD programs at U.S. institutions, explore critical health topics such as cardiovascular disease, leading female cancers, and the role of hormones. This initiative encourages diverse applicants and promotes innovative proposals that address health concerns disproportionately affecting women. With a commitment to fostering research excellence, the FWW Fellowship Award empowers the next generation of health leaders.
Women's Health

Illinois Mutual Employees’ Children Scholarship

Community Foundation of Central Illinois
Private
United States
US $2,000

Who We Are

The Community Foundation of Central Illinois will make a sustainable philanthropic impact in our community through visible leadership in connecting people who care with causes that matter.

Illinois Mutual Employees’ Children Scholarship Fund 

The Illinois Mutual Employees’ Children Scholarship Fund was established by Illinois Mutual Life Insurance Company to provide scholarship support for the children of employees who are graduating from high school or are undergraduate college or vocational students who will be enrolled full time.

For general scholarship questions, please contact Illinois Mutual’s Community Relations Department. For questions about the application process or required materials, contact the Community Foundation of Central Illinois at 309-674-8730 or amanda@communityfoundationci.org.

Education - Higher Education Vocational & Trade Education

Oak Foundation: Learning Differences Grant Programme

The Oak Foundation USA
Private
Ethiopia, Europe +1 more
Unspecified amount
The Oak Foundation's Learning Differences Grant Programme aims to foster equitable educational experiences for students with learning differences, particularly those marginalized by racism and poverty. Through strategic partnerships with not-for-profit organizations, the program enhances understanding of diverse learners' needs, translates knowledge into effective practices, and influences systemic changes to create supportive learning environments. The initiative emphasizes the importance of community involvement, ensuring that students' voices are heard and their educational needs are met.
Learning Disabilities

Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $5,000,000
The Environmental Health Sciences Core Centers Program (P30) invites grant applications to support innovative research in environmental health. These centers serve as critical hubs for advancing the goals of the 2025-2029 NIEHS Strategic Plan, providing essential infrastructure and resources for collaborative research. By fostering community engagement and translational research, the program aims to enhance understanding of the connections between environmental factors, human biology, and disease, ultimately improving public health outcomes.
Environmental Health

ASTRO-ACS Clinician Scientist Development Grant (CSDG)

American Cancer Society
Association/Society
American Samoa, Guam +4 more
US $405,000 - US $675,000
The American Cancer Society (ACS) and the American Society for Radiation Oncology (ASTRO) co-fund the Clinician Scientist Development Grant (CSDG), aimed at advancing the research careers of clinician scientists in radiation oncology. Eligible applicants are full-time faculty members at U.S. institutions with a doctoral degree and an active clinical license. The grant supports research for 3 to 5 years, providing $135,000 annually for direct costs, plus allowable indirect costs, while encouraging diversity in applications.
Cancer / Oncology

Big 30 Athletic Fund

Cattaraugus Region Community Foundation
Private
United States
Unspecified amount

Big 30 Athletic Fund

This scholarship is for four graduating high school seniors from Big 30 participant schools. One award overall from any Big 30 school, one for a student from Cattaraugus County, one for a student from Allegany County, and one for a student from Pennsylvania. Students must have participated in at least two sports for all four years of high school. Emphasis will be placed on involvement in sports, but academic achievement will also be considered. Financial need may be considered.

Education - Higher Education Sports & Athletics

Carroll Swanson Memorial Scholarship for the Performing Arts

Cattaraugus Region Community Foundation
Private
United States
Approximately US $200

Carroll Swanson Memorial Scholarship for the Performing Arts

This fund was established to provide a scholarship for a student at the following schools: Allegany-Limestone, Olean and Portville who has participated in a school music program (band or choral).

Education - Higher Education Performing Arts

Daniel and Patrick McCarthy Scholarship

Cattaraugus Region Community Foundation
Private
United States
Unspecified amount

Daniel and Patrick McCarthy Scholarship

Given through the generosity of the Catherine M. Cridler Trust and named in honor of Daniel McCarthy, one of the founders of Olean Business Institute, this scholarship is available to students pursuing undergraduate business studies. The fund was renamed in 2023 to include Patrick McCarthy, son of Daniel, who also served as director of Olean Business Institute for many years.

Education - Higher Education Business Education

Rancho Santa Fe Women's Fund Grant

Rancho Santa Fe Foundation
Private
San Diego County, California
US $25,000 - US $75,000
The Rancho Santa Fe Women's Fund Grant aims to empower women in philanthropy to enhance community impact through collective giving. Focused on health and social services, this initiative prioritizes projects addressing homelessness, climate change, and elderly issues. Eligible organizations must be 501(c)3 and demonstrate effective management and results. Notably, discrimination in any form disqualifies applicants. Preference will be given to projects in North County, ensuring funds support local community needs.
Military & Veterans Services Women & Girl Services

Chautauqua Cattaraugus Board of Realtors Scholarship

Cattaraugus Region Community Foundation
Private
United States
US $500

Chautauqua Cattaraugus Board of Realtors Scholarship 

This scholarship benefits students in Chautauqua and Cattaraugus counties, in good academic standing, with a preference for those entering a business-related field of study. Two $500 awards are made to two students each from Cattaraugus and Chautauqua Counties.

Education - Higher Education Business Education

CIELO Fund Grant Opportunity

The Inland Empire Community Foundation (IECF) Serving Riverside & San Bernardino Counties
Private
Riverside County, California, San Bernardino County, California
Up to US $15,000
The CIELO Fund at the Inland Empire Community Foundation aims to uplift and invest in Latino-led initiatives in the Inland Empire. Launched in 2022, it reflects the region's growing Latino majority and addresses disparities in areas such as education, health, and economic mobility. The fund emphasizes equitable growth and community collaboration to foster a vibrant future for all residents. With a focus on leadership development and environmental equity, it champions the aspirations of the Latino community while tackling pressing local challenges.
Hispanic and Latino Services

Limited Competition: The NHGRI Analysis, Visualization, and Informatics Lab-space (AnVIL) (U54 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NHGRI's Analysis, Visualization, and Informatics Lab-space (AnVIL) program is set for a limited competition renewal to enhance a cloud-based platform that supports genomic research. With over 5 petabytes of data accessible to researchers, AnVIL fosters collaboration and innovation while adhering to FAIR principles. The renewed focus will include improved scalability, interoperability, and robust security measures. Additionally, training initiatives will ensure researchers maximize the potential of AnVIL's multimodal datasets. The funding opportunity is expected in 2027.
Human Genome & Genetics

Institutional Research Grants (IRG)

American Cancer Society
Association/Society
American Samoa, Guam +4 more
Up to US $360,000
The Institutional Research Grants (IRG) program by the American Cancer Society provides essential seed funding for newly independent investigators to launch cancer research projects. Aimed at junior faculty, these grants offer $120,000 annually for three years, supporting the development of preliminary results necessary for competing for larger national grants. Eligible applicants must be at US academic institutions and hold the rank of Associate or Full Professor, with a proven track record in research and mentorship.
Cancer / Oncology

Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Radiation Oncology-Biology Integration Network (ROBIN) Centers, funded by the National Cancer Institute (NCI), aims to enhance national radiation oncology infrastructure through collaborative research. This initiative supports studies on biological responses to radiation treatment in cancer patients, focusing on understanding tumor and tissue changes. By integrating various scientific disciplines and collecting comprehensive data, ROBIN intends to improve cancer care, optimize treatment strategies, and accelerate translational discoveries to enhance patient outcomes.
Cancer / Oncology

AMVETS Children and Grandchildren Scholarship

Amvets National Service Foundation
Private
United States
US $4,000
The AMVETS Children/Grandchildren Scholarship supports the educational aspirations of children and grandchildren of honorably discharged U.S. veterans and active military. This scholarship aims to bridge financial gaps after all federal and state assistance has been utilized. Eligible applicants must be U.S. citizens, high school seniors, and demonstrate financial need while enrolled in accredited four-year universities. Incomplete applications will be disqualified, ensuring that the award goes to deserving candidates committed to their education.
Military & Veterans Services Academic Scholarship Programs

Judith B. Cutcomb Scholarship

Napa Valley Community Foundation
Private
United States
US $1,000

Napa Valley Community Foundation

We work side-by-side with local donors and nonprofits to tackle the most important challenges our Valley faces.

Our Board and staff are completely dedicated to the people and causes of Napa Valley and represent communities from American Canyon to Calistoga. They share skills, perspectives and the collaborative spirit that define our Napa Valley diversity.

Judith B. Cutcomb Scholarship

The Judith B. Cutcomb Scholarship is offered by CalRTA Napa Valley and administered by Napa Valley Community Foundation. It is awarded in memory of Judith B. Cutcomb, a St. Helena educator. The Cutcomb Scholarship supports current St. Helena Unified School District teachers who are continuing their education or graduates of St. Helena High School studying to be educators. Previous recipients of the scholarship are eligible to reapply.

Education - Higher Education Teacher Development & Training

Linn County- Samaritan Lebanon Community Hospital Auxiliary Scholarship

Samaritan Health Services
Private
Linn County, Oregon, United States
US $1,000

Who We Are

Thousands of your friends and neighbors make up Samaritan Health Services. We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of your ability to pay.

Linn County- Samaritan Lebanon Community Hospital Auxiliary Scholarship

East Linn County students currently attending college and majoring in a medical field are invited to apply for the Samaritan Lebanon Community Hospital $1,000 Auxiliary Scholarship.

Academic Scholarship Programs Education - Higher Education

Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional) (357744)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
This funding opportunity supports exceptionally promising Early Stage Investigators in genomics, encouraging innovative research across various fields such as genomic sciences and medicine. Applicants must submit their proposals by 5:00 PM local time of their organization. The initiative, led by the US Dept. of Health & Human Services through the NIH, aims to foster long-term career development in genomic research while addressing its ethical, legal, and social implications.
Genetics & Genomics Medical Ethics

Daisy Cavalli Scholarship Fund

Napa Valley Community Foundation
Private
United States
US $5,000

Napa Valley Community Foundation

We work side-by-side with local donors and nonprofits to tackle the most important challenges our Valley faces.

Our Board and staff are completely dedicated to the people and causes of Napa Valley and represent communities from American Canyon to Calistoga. They share skills, perspectives and the collaborative spirit that define our Napa Valley diversity.

Daisy Cavalli Scholarship Fund

The Daisy Cavalli Scholarship Fund benefits graduating seniors who attend a Napa Valley Unified School District high school and will be enrolling in a trade school, community college, or four-year college/university. Recipients will receive funding for each year that they are enrolled as a full-time student.

Consideration is given to first generation college students (i.e. neither parent has obtained a Bachelor’s Degree).

Education - Higher Education Vocational & Trade Education

Research Scholar Grants (RSG) Winter Cycle

American Cancer Society
Association/Society
American Samoa, Guam +4 more
Up to US $215,000
The Research Scholar Grants (RSG) by the American Cancer Society support independent researchers engaged in cancer-related studies. Eligible applicants must be affiliated with US academic institutions and have been appointed as independent faculty for less than ten years. Grants provide funding up to $215,000 annually for direct costs and allow for 10% indirect costs, with project durations of up to four years, fostering innovative cancer research across various priority areas.
Cancer / Oncology

Large Grants for Nonprofit Organizations in California Highlights

Looking for large grants for nonprofit organizations in California?


Read more about each grant below or start your 14-day free trial to see all large grants for nonprofit organizations in California recommended for your specific programs.

Grant Insights : Large Grants for Nonprofit Organizations in California

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

400+ Large Grants for Nonprofit Organizations in California grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

200+ Large Grants for Nonprofit Organizations in California over $25K in average grant size

200+ Large Grants for Nonprofit Organizations in California over $50K in average grant size

37 Large Grants for Nonprofit Organizations in California supporting general operating expenses

300+ Large Grants for Nonprofit Organizations in California supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations in California?

Most grants are due in the first quarter.

Q1
27.8%
Q2
26.4%
Q3
22.9%
Q4
22.9%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations in California?

Grants are most commonly $100,000.

$0 $0 Min.
$100,000 $100 K Median
$2,121,130 $2.1 M Average
$150,000,000 $150 M Max.

Average Grant Size

What's the typical amount funded for California?

Grants are most commonly $145,539.

$145,539

Total Number of Grants

What's the total number of grants in Large Grants for Nonprofit Organizations in California year over year?

In 2024, funders in California awarded a total of 256,564 grants.

2022 237,186

2023 236,635

2024 256,564

Top Grant Focus Areas

Among all the Large Grants for Nonprofit Organizations in California given out in California, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Large Grants for Nonprofit Organizations in California changing over time?

Funding has increased by -1.38%.

2022 $34,364,756,699

2023 $37,770,770,141
9.91%

2024 $37,247,795,891
-1.38%

California Counties That Receive the Most Funding

How does grant funding vary by county?

Los Angeles County, San Francisco County, and San Mateo County receive the most funding.

County Total Grant Funding in 2024
Los Angeles County $10,841,756,858
San Francisco County $5,409,542,294
San Mateo County $5,358,878,304
Santa Clara County $3,811,026,208
Alameda County $3,749,322,182

Related Grants in California

Browse Other Nonprofit Operations & Capacity Grants in California

Browse Grants For Nearby Locations

Browse Grants by Major US Cities within California