Best Large Grants for Nonprofit Organizations in California

The Fred Jones Family Foundation Grant supports 501(c)(3) organizations in central Oklahoma, focusing on education, arts, and beautification projects. The foundation meets every 90 days to evaluate new donation requests. Eligible applicants must adhere to specific guidelines, including submitting a Board of Directors list with at least six members. The foundation prioritizes projects that enhance the quality of life and foster cultural growth in the region.

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To enhance our community through philanthropy.

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Dale & Thomasina Trout Memorial Fund

About the fund

The Trout Scholarship is awarded to Benton County high school graduates who have excelled in academics and school activities or athletics.

The AICEF Overseas Travel Grant provides funding of $3,000 to Indonesian PhD students enrolled in accredited US universities for dissertation research in Indonesia. Applicants must demonstrate commitment to returning to Indonesia after their studies and show preparedness in their field. This grant aims to support academic endeavors that foster international collaboration and knowledge exchange, benefitting both students and their home country.

The Frances A. and Joseph B. Levy Family Scholarship Fund, established by the Dallas Jewish Community Foundation, offers a $1,255 scholarship to Jewish doctoral students in veterinary medicine. This fund honors the Levy family's passion for animals and aims to support future veterinarians in their education. Eligible candidates must be enrolled in accredited veterinary programs nationwide, helping them advance their skills to ensure the health and welfare of animals and their communities.

The Diana Jacobs Kalman/AFAR Scholarships for Research in the Biology of Aging offer MD, DO, PhD, or combined-degree students the opportunity to conduct research on aging. Established by Diana Jacobs Kalman, a leader in aging science, the program addresses the challenges of an aging population. By awarding up to ten scholarships, it aims to foster innovative research and improve the quality of life for older adults. Proposed projects should focus on specific areas like immune function, inflammation, and genetic control of longevity.

The Elsa U. Pardee Foundation has been a pioneer in cancer research funding since 1944, providing over $110 million to more than 300 institutions across the U.S. It supports innovative approaches by both new and established researchers, ensuring diverse ideas receive necessary funding. Additionally, the Foundation addresses immediate financial needs for cancer patients, allocating about one-third of its grants to assist those in need. This dual focus on research and patient support distinguishes the Foundation in the fight against cancer.

Knights of Pythias Scholarship Fund

In 1950, the membership roster for the Corvallis lodge of the Knights of Pythias, Valley Lodge No. 11 had more than 250 names, but membership declined over the years and the club subsequently disbanded. In 1992, as remaining members began discussions about how to distribute the assets of the lodge, Benton Community Foundation (BCF) emerged as a natural choice.

“We felt it would be best to keep the money in the community where our members lived and worked,” said Bob Bareinger, a member in the organization since 1943 and an officer since 1954. The lodge tried to give BCF the entirety of assets, including the deed to the building, but the Oregon Chapter that has jurisdiction over it stepped in and required the assets to be distributed differently. BCF received one-third of the lodge assets, which means that the Knights of Pythias will continue to serve the youth of Benton County in perpetuity by providing annual scholarships to graduates of Benton County high schools.

Scholarships for High School Seniors

Mid-Shore Community Foundation awards scholarships to high school seniors in Caroline, Dorchester, Kent, Queen Anne’s and Talbot Counties, who are planning to attend a college, university, or trade school. In general, scholarships are awarded to students who demonstrate academic achievement, community service, financial need, and other criteria specified by the donor.

Omer and Marie Dulin Scholarship

Awarded to Mid-Shore students, who are planning to pursue programs in Agriculture.

The West-Gray Scholarship Fund, established in 2014, supports undergraduate and graduate students in applied geology who demonstrate academic excellence and are members of the Association of Environmental & Engineering Geologists. This fund aids students conducting field studies in environmental and engineering geology particularly in the eastern United States, fostering future professionals in the field.

The ACS Professor Award, presented by the American Cancer Society, recognizes full professors who have significantly advanced cancer research. This honorific award aims to support innovative pursuits in cancer research with a budget of up to $80,000 per year for five years. Applicants are expected to demonstrate impactful contributions and leadership in the field, along with a commitment to mentorship and community engagement. The award highlights the importance of ongoing advocacy and research in improving cancer treatment and prevention.

Seattle Foundation

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Walter H. Meyer — Garry L. White Memorial Scholarship

This $5,000 scholarship is available to non-traditional students working towards an undergraduate (must be over 24 years old) or graduate (must be over 30 years old) degree.

The AFAR Grants for Junior Faculty and Glenn Foundation for Medical Research offer up to $160,000 for one- to two-year research projects focusing on the biology of aging. Aimed at early career faculty, these grants support innovative studies not limited to age-related diseases but rather the fundamental mechanisms of aging. Approximately 10 grants will be awarded in 2026, with funding starting July 1. Applicants must be independent investigators within 10 years of their postdoctoral training.

The Investigators in the Pathogenesis of Infectious Disease Grant Program, funded by the Burroughs Wellcome Fund, aims to support early-career assistant professors studying human infectious diseases. With a budget of $505,000 over five years, it encourages innovative research on the interplay between human systems and infectious agents, fostering multidisciplinary approaches to enhance our understanding of disease mechanisms and health maintenance.

The Gibson Foundation, now known as Gibson Gives, is dedicated to enhancing lives through music by supporting 501(c)(3) organizations. Their mission is to inspire and amplify the power of music through guitars for all generations. With a commitment to music education and wellness, Gibson Gives is making a positive impact worldwide, ensuring that music continues to shape the lives of musicians and enrich communities. Donations are reviewed monthly, requiring a minimum of four weeks for processing.

The Brookreson Trust Grant aims to support financing homes for the blind and organizations that assist them. This grant is targeted towards 501(c)(3) exempt organizations across all states. The program focuses on key areas such as education, health, and human services, ensuring that vital resources are directed towards enhancing the quality of life for the visually impaired community. Grants are specifically intended for initiatives that facilitate housing and support services.

Seattle Foundation

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Nora Stone Smith Scholarship

The Nora Stone Smith Scholarship honors and gives financial support to deserving immigrant high school seniors and students who have graduated in the past year and have participated in an ESL/ELL program at some point in their lives. This scholarship is available for all ESL/ELL students, regardless of their citizenship status. Undocumented students are encouraged to apply. This scholarship is $2,000 and renewable for 2 or 4 years.

The James Paul Sutton Medical Research Fund Grant supports non-profit organizations engaged in cancer and medical research, established through a trust by the Sutton family. Eligible organizations must be 501(c)(3) exempt. Preference is given to cancer research initiatives, while grants are not available for individuals, political groups, or for-profit entities. This fund aims to sustain medical research efforts for the long term, continuing the legacy of the Sutton family.

The American Cancer Society's Mentored Research Grants for Postdoctoral Fellowships (PF) aim to support emerging researchers in their training programs, fostering their transition to independent cancer research careers. Eligible candidates include US citizens or non-citizens with valid visas who have completed their doctoral degrees within the last four years. The fellowship offers funding for up to three years, with stipends of $66,000 to $70,000 annually, alongside allowances for health insurance and professional development.

The Seymoure, Fred and Mildred (Young) Memorial Scholarship Fund offers a $500 scholarship to a Central Noble High School senior or graduate, or a resident of the Albion area pursuing a BS or MS in education. Established by the Noble County Community Foundation, this fund aims to support future educators in making a positive impact in their communities. Since 1991, the foundation has been dedicated to enhancing the quality of life in Noble County.

The Generation of Environmental Leaders Program (GELP) invites youth aged 18-35 from Canada, Mexico, and the United States to propose innovative solutions to environmental challenges. This initiative not only empowers young leaders through mentorship and networking but also provides seed funding to support impactful projects. By encouraging collaboration and sustainable practices, GELP aims to foster long-term benefits for communities and the environment, ultimately preserving shared natural resources.

The USS ST. LOUIS (LCS 19) Scholarship, established by the Commissioning Committee in 2020, supports crew members and their dependents pursuing undergraduate degrees or technical training. Administered by The Scholarship Foundation of St. Louis, it awards up to $12,000 annually, renewable for up to ten semesters. This initiative honors the commitment of the USS ST. LOUIS crew while fostering educational advancement and community engagement.

The Clinician Scientist Development Grant (CSDG) by the American Cancer Society supports full-time faculty aiming to become independent clinician scientists while maintaining clinical practice. Eligible applicants must hold a doctoral degree, an active clinical license, and have clinical care experience. The grant provides funding of $135,000 annually for 3 to 5 years, including allowable indirect costs, to advance cancer research in key priority areas.

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Women at Microsoft Scholarship

This scholarship supports high school seniors or graduates or current college undergraduates who self-identify as female or as non-binary (a spectrum of gender identities that are not exclusively masculine or feminine). This scholarship is a $5,000 award with up to seven (7) scholarships granted.

The Preserve Route 66 Legacy Business Grant Fund offers financial support to enhance historic sites and stimulate economic growth along the iconic Route 66. Targeting projects that reflect the diverse narratives of historically underrepresented communities, this grant emphasizes mural and painting initiatives in preparation for the 2026 centennial celebration. Grants range from $5,000 to $10,000, with no matching funds required, fostering inclusivity and preservation of cultural heritage along the corridor.

Community Foundation of Mendocino County

The Community Foundation of Mendocino County is a county-wide nonprofit organization that administers permanent charitable funds established through gifts and bequests from individuals, families, businesses, and other organizations.

Scholarships

The Community Foundation of Mendocino County Scholarship program provides scholarship opportunities for local students to help pursue their educational goals and achieve their higher education dreams.

The Community Foundation of Mendocino County provides scholarships for all seven regions of the county, as well as for specific academic and professional goals.

Randy Clark Memorial Vocational Scholarship

Created in memory of Randy Clark, who died February 16, 2002 at the age of 21, to support high school and college students who plan to pursue vocational education at trade schools or community colleges.

The Emergency Medicine Interest Group Grant (EMIG), funded by the Society for Academic Emergency Medicine Foundation, supports medical student interest groups in enhancing emergency medicine education. Grants of up to $500 are awarded for one year, with potential for renewal. Eligible applicants include established or developing EMIGs at medical schools, focusing on educational initiatives. This grant aims to foster innovation in teaching methodologies and support resources for students pursuing education in emergency medicine.

The Rural Health Fellows Leadership Program, offered by the National Rural Health Association (NRHA), is an intensive yearlong initiative aimed at cultivating a diverse network of rural health leaders. Selected participants engage in leadership training, policy advocacy, and collaborative projects. The program includes monthly virtual sessions, in-person meetings at key conferences, and opportunities for financial support, thereby empowering fellows to make a significant impact on rural healthcare.