Best Large Grants for Nonprofit Organizations in California

The Ned K. Johnson Early Investigator Award, presented by the American Ornithological Society, recognizes exceptional early-career researchers in ornithology. Awardees receive a certificate, a $1,500 honorarium, and complimentary registration for the annual meeting, where they can present a plenary. Candidates must have received their doctorate between 2019 and 2022, and demonstrate ethical standards aligned with the AOS Code of Conduct. This award fosters leadership and innovation in bird conservation and research.

The Urban and Community Forestry Grants by CAL FIRE aim to create green schoolyards in California to enhance children's health and education while addressing climate change. Funding of $13.5 million will support TK-12 schools in specific neighborhoods, focusing on nature-based solutions to alleviate heat and improve urban environments. Projects must benefit disadvantaged communities and require local educational agency support. This initiative underscores the importance of urban forestry in fostering resilient and sustainable communities.

The Bono Brothers Memorial Trust Grant supports needy children in Marin County, California, through Catholic charitable organizations. Established in 1962 by Joseph Bono, the Trust awards an average of four grants annually to eligible 501(c)(3) organizations. The funds are intended for the care, support, maintenance, and education of these children, ensuring they receive necessary assistance and resources for a better future.

The BIE Internship Funding for STEM Students, offered by the Native Forward Scholars Fund, provides financial assistance to Native students for approved internships related to STEM. This initiative helps cover costs such as travel, living expenses, and daily commuting, facilitating valuable professional experiences. By supporting these students, the program aims to enhance Native representation in STEM fields and empower future leaders within their communities, contributing positively to society's growth and diversity.

The BJA FY 2026 Smart Reentry Demonstration Program aims to support state, local, and tribal governments in implementing effective reentry strategies for individuals transitioning from correctional facilities back to their communities. This program encourages comprehensive interventions designed to reduce recidivism by addressing various reentry needs, as outlined in the Second Chance Act. Applications are due by October 1, 2026, at 8:59 PM ET, and are submitted through JustGrants.

The NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Not Allowed) invites proposals for high-risk, multi-center observational studies on diseases relevant to NIDDK's mission. Applicants are encouraged to consult with NIDDK staff and must complete planning activities before submission. Key deadlines for applications span from February 2025 to October 2026, with optional Letters of Intent due 30 days prior to full proposals.

The Lundbeck US Charitable Fund focuses on enhancing brain health through impactful donations. Established to support organizations dedicated to brain health, it addresses pressing needs by funding innovative strategies and community collaborations, particularly for at-risk populations. The Fund aims to transform lives and improve mental health care, with a commitment to responsible giving. With over 20 organizations supported in 2023, it drives meaningful change in communities affected by brain disorders.

The Marion Jenkinson Service Award, presented by the American Ornithological Society, honors early- and mid-career ornithologists for their extensive volunteer contributions and service to the society. This award includes a framed certificate and recognizes individuals who exemplify high ethical standards aligned with the AOS Code of Conduct. The award aims to foster a diverse and supportive ornithological community while promoting bird conservation and scientific study.

The Peter R. Stettenheim Service Award, established by the American Ornithological Society in 2018, honors individuals who have made significant contributions to ornithology and the society. This award recognizes those who have served in various capacities, highlighting volunteer work, mentorship, and committee involvement. It is named after Peter Stettenheim, a notable leader in ornithology, who was dedicated to advancing the field and supporting fellow ornithologists throughout his career.

The Ralph W. Schreiber Conservation Award, presented by the American Ornithological Society (AOS), honors individuals or small teams for exceptional contributions to bird conservation. Recognizing efforts in applied research, habitat preservation, and educational initiatives, this award aims to encourage the scientific study of birds and promote ethical practices in ornithology. Nominees must be AOS members, ensuring a commitment to the society's mission of fostering a diverse and engaged ornithological community.

The North Coast Seafood Extension Fellowship, funded by California Sea Grant, aims to enhance seafood marketing and production opportunities in California's rural North Coast region. The fellowship will support collaboration among local partners to improve seafood availability and sales, strengthen marketing efforts, and develop infrastructure. The fellow will engage in training and educational initiatives for commercial fishers, facilitating connections between them and regional markets, all while promoting sustainable practices and community resilience.

The BTCF: Simple Gifts Fund Grant supports young artists aged 13-19 in the Berkshire Taconic region, providing financial assistance for summer enrichment programs in the arts. Established in 1998 in memory of folk singer Bill Crofut, the fund aims to empower youth through small grants that can cover costs for tuition, art supplies, or living expenses. The grant fosters creativity and personal growth, ensuring that young individuals have opportunities to pursue their passions.

The William Brewster Memorial Award, awarded by the American Ornithological Society, recognizes exemplary contributions to ornithological science through a significant body of work on Western Hemisphere birds published in the last decade. This prestigious award honors the legacy of William Brewster, a founding member of the American Ornithologists' Union, and includes a medal and honorarium funded by the William Brewster Memorial Fund. Nominations are open to all, fostering diversity in ornithology.

The Dell Scholars Program, established by the Michael & Susan Dell Foundation, provides scholarships and support to empower students in their journey towards college graduation. It offers flexible funding for tuition, housing, and essential expenses, ensuring students can focus on their education. Alongside financial aid, scholars receive academic coaching, career guidance, and mental health resources, fostering resilience and success. Since 2004, it has helped over 6,000 scholars, including 4,500 graduates, achieve their academic goals.

The Mike & Sofia Segal Foundation Grant provides vital funding to nonprofit organizations focused on intellectual freedom, medical research for rare diseases, Jewish heritage preservation, elder care, and climate change initiatives. By supporting innovative projects that align with their mission, the foundation aims to uplift communities and foster meaningful societal contributions. Organizations must be 501c-3 compliant and demonstrate a clear plan for engagement with beneficiaries and measurable objectives to be eligible for funding.

The Lundbeck US Charitable Fund focuses on enhancing brain health through sponsorships that support various initiatives. These sponsorships are available to both non-profit and for-profit organizations, provided they align with Lundbeck's mission. Funds are primarily allocated for educational or awareness events, with an emphasis on community outreach and collaboration to address gaps in care, especially for vulnerable populations. By fostering innovative strategies, the Fund aims to drive meaningful change in the field of brain health.

The Desert Tortoise Council invites proposals for conservation projects aimed at enhancing desert tortoise populations and habitats. With a funding opportunity of $9,000, the RFP emphasizes the importance of in situ conservation efforts such as habitat restoration and predator control. Projects must be completed within the current year in the Mojave Desert region. Applicants are required to submit detailed proposals, including budgets and project descriptions, and must report outcomes post-completion.

This NOFO invites applications for innovative research aimed at developing and implementing interventions to prevent and treat substance use disorders (SUDs) and overdose. It encourages studies that can rapidly advance candidate solutions towards regulatory approval or clinical use, while also addressing co-morbid SUDs. The initiative supports a wide range of research including basic, clinical, translational, and implementation strategies to tackle drug misuse and related health issues, such as HIV/AIDS.

The Melanoma Research Resident and Fellowship Grant offers $10,000 to support early-career residents and fellows in conducting clinical or laboratory research focused on melanoma. This grant encourages innovative approaches to understanding prevention, detection, and treatment of melanoma, including special emphasis on ocular melanoma. Eligible candidates must have a qualified mentor and conduct research at a U.S. institution. This initiative aims to enhance the landscape of melanoma research and foster the next generation of researchers.

This funding opportunity encourages applications for clinical observational studies focused on musculoskeletal, rheumatic, and skin diseases. It aims to gather essential data for designing future clinical studies, enhancing understanding of disease symptoms, progression, and patient outcomes. Observational studies supported by this initiative will contribute to the development of objective biomarkers and effective outcome measures. Applicants are invited to address key challenges in clinical project design, ensuring a robust foundation for subsequent clinical trials.

The T32 Postdoctoral Fellowship in Mental Health Services Research is a two-year program supported by the National Institute of Mental Health. It trains emerging researchers in health systems research focusing on mental health and suicide prevention. The fellowship emphasizes mentorship, research methods, and professional development, preparing fellows to secure independent funding. Candidates with PhDs, MDs, or equivalent degrees, especially those from underrepresented backgrounds, are encouraged to apply. More information is available through the program's website.

The Arthritis National Research Foundation supports early career researchers in their quest to advance understanding and treatment of arthritis and related autoimmune diseases. Annually, the foundation grants 10 to 20 awards of $125,000 each for two years. Focus areas include osteoarthritis, rheumatoid arthritis, lupus, and more. Eligible investigators must hold an M.D. or Ph.D., be affiliated with a U.S. nonprofit research institution, and commit significant research time. Applications from prior grant recipients or those with certain NIH grants are ineligible.

The DFO Research, Education, and Conservation Grant supports projects focused on birds and their habitats, prioritizing initiatives in the Denver area and Colorado's Front Range. Established in 1994, the fund encourages research, education, and conservation efforts with grants typically under $2,000. Recent funded projects include studies on owl habitats and educational programs for young birders. The fund aims to advance knowledge and appreciation of avian species through targeted financial support.

The Mayer and Morris Kaplan Foundation Environment Grant aims to support initiatives that combat climate change, prioritizing efforts to reduce fossil fuel consumption and enhance climate education for young adults. The foundation emphasizes innovative solutions and partnerships to address both immediate and long-term environmental challenges. Areas of focus include climate and clean energy policy, as well as providing scientifically accurate climate change education. By leveraging data and research, the foundation seeks to empower organizations dedicated to creating impactful change.

The Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) aim to support clinical trials that can be completed within a limited timeframe. This funding opportunity encourages a variety of exploratory studies that align with the NIAMS mission, focusing on interventions such as drugs, biologics, devices, and various therapies. Applications are due by 5:00 PM local time of the applicant organization.

The General Surgery Resident Research Initiation Grant aims to engage General Surgery Residents in research related to colorectal diseases. With an annual funding of $20,000, this grant supports both clinical and laboratory-based research. It is geared towards residents or recent graduates of approved General Surgery programs, prioritizing those with aspirations in Colon and Rectal Surgery. This initiative fosters innovative research to enhance patient care and surgical techniques in the field.

The Aerie Real Foundation™ Community Grant aims to enhance confidence, inclusion, and sustainability among young women while supporting non-profit organizations in the US and Canada. Grants of up to $10,000 are available to programs focused on mental well-being, fostering inclusive communities, and environmental protection. Applications are accepted from certified 501c3 nonprofits, with funding allocated for projects that align with the Foundation's mission. The goal is to empower the next generation and create a positive impact in local communities.