Best Operating Grants for Nonprofits in California

The FY26 Autism Research Program's Idea Development Award from the US DOD aims to support groundbreaking research that improves outcomes for Autistic individuals. This award encourages innovative, high-risk projects that can lead to significant advancements in autism research. Applications must address specific areas of interest or justify the importance of the research problem. A unique Partnering Principal Investigator option allows two researchers to collaborate on a single project, enhancing the potential for impactful discoveries.

Access Advocate for Clinical Research Participation

Objective:

This program will support implementation and evaluation of a Parkinson’s disease (PD) focused Access Advocate model designed to increase inclusive research participation. Funding will support Access Advocates at clinical sites to build practical, relationship based pathways to improving representative research enrollment and retention.

Funding Details:

• Duration: 24 months 
• Award Amount: $200,000 

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) and its inclusive recruitment strategy has examined what barriers and motivators shape participation (e.g., FIRE-UP PD study3) as well as funded sites to pilot tactics that address those barriers (e.g., Black & African American Connections to Parkinson’s Disease study4). Now we aim to scale and validate approaches that show early promise by investing more deeply and measuring impact across settings.

This program will fund advocates at clinical sites to build practical, relationship-based pathways to improving representative research enrollment and retention. These support staff will help patients and care partners navigate health system complexity and everyday needs that often determine whether research participation is feasible. They will help address barriers such as transportation, caregiving responsibilities, language needs, and insurance and financial strains by connecting people to resources, coordinating logistics and providing consistent follow-up. These advocates also should discuss research participation opportunities with patients and connect them to recruiting studies.

The model is grounded in the idea that research participation is more feasible when (i) foundational practical needs are addressed first and (ii) raised by a trusted health care partner. By helping to reduce practical barriers, advocates are expected to increase screenings, enrollment conversion and retention across key trial milestones.

This program will test these hypotheses and further establish training, infrastructure needs and sustainability of such positions.

Program Goal

This program aims to:

• Support establishment of site-based Access Advocates to support potential participants and care partners across multiple active or planned PD studies.
• Evaluate needs and opportunities for onboarding and ongoing training for advocates in PD and clinical research fundamentals as well as site and local resources.
• Recommend repeatable workflows for identifying prospective participants, assessing barriers, connecting them to resources, coordinating logistics and supporting follow-up.
• Collect and report a core set of evaluation metrics across sites (reach, encounters, referrals, screened, enrolled, retained), including barrier tracking and resolution.
• Evaluate the impact of Access Advocates in recruiting and retaining underrepresented community individuals to/in Parkinson’s studies.
• Evaluate the impact of Access Advocates on “health system value” indicators (e.g., appointment adherence/show rates, medication access/adherence proxies) that could support funding sustainability from other sources.
• Establish a cross-site learning community that enables funded sites to share lessons, refine the Access Advocate model and inform broader adoption beyond the funding period.

The CTTSS Postdoctoral Scholars Research Award, established by the Society of Toxicology (SOT), invites current postdoctoral scholars attending the SOT Annual Meeting to apply if they have submitted an abstract for presentation. The award includes a monetary prize and a recognition certificate for the 1st place winner, with potential additional awards. This prestigious recognition highlights innovative research in toxicology, emphasizing the Society's commitment to enhancing human, animal, and environmental health.

The Earthwatch Institute's Teach Earth Fellowship connects K-12 teachers with scientists through immersive research expeditions. Celebrating 50 years, this program empowers educators to inspire students with hands-on environmental science experiences. Teachers gain confidence, collaborate with peers, and develop impactful curricula. The fellowship includes workshops, networking opportunities, and resources to enhance environmental education in classrooms. Participants return with renewed purpose, ready to engage their communities in conservation efforts.

The FY26 Autism Research Program Clinical Trial Award aims to rapidly implement clinical trials that significantly impact autism treatment and management. Projects may range from small proof-of-concept trials to large-scale studies assessing efficacy in relevant populations. Applications are encouraged to partner experienced and early-career investigators and must include community collaborations to enhance research impact. At least one community partner is required to provide ongoing consultation throughout the project.

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

In God We Trust, Mitchelle T. Savage Memorial Scholarship Fund

The In God We Trust, Mitchelle T. Savage Memorial Scholarship was established to provide educational opportunities beyond high school for Battle Creek area graduates or graduating seniors. Eligible recipients will be graduating seniors from Battle Creek area public and private schools who will be attending a college that is a member of the Council for Christian Colleges and Universities.

The Shoshana Foundation Grant, established in 1986, aims to support young American opera singers by providing essential funding and career development opportunities. Nominated by music schools and opera companies, recipients can receive supplemental grants based on merit and need. This initiative honors Richard F. Gold's vision to nurture talent in opera, ensuring the art form's future. Participating institutions include The Juilliard School and Houston Grand Opera, fostering the growth of emerging artists in the competitive landscape of opera.

The Frederic C. Collin Trust Grant supports 501(c)(3) organizations in promoting polo and tennis, especially among youth. Established under Frederic C. Collin's will, it offers grants ranging from $2,000 to $3,800, with an annual total giving of approximately $9,000. Applications are accepted year-round for consideration during the annual grant meeting. This initiative aims to enhance participation in these sports, fostering talent and interest among young players.

Pfizer’s Core Values of Social Responsibility and Philanthropy

About

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place. It was Charles Pfizer’s vision at the beginning and it holds true today.

Improving Health Outcomes in Patients with ATTR-CM Through the Development of a Shared Decision-Making Tool (Decision Aid)

Overview

Transthyretin Amyloid Cardiomyopathy (ATTR-CM) is a progressive, lifethreatening condition associated with significant morbidity, mortality, and burden on patients, caregivers, and healthcare systems. The multisystemic disease course is often characterized by diagnostic delays, complex treatment pathways, and evolving therapeutic options, which can create uncertainty and decisional conflict for patients and clinicians alike. Shared decision-making (SDM) has emerged as a critical component of patientcentered care1, particularly in complex and preference-sensitive conditions such as ATTR-CM. Well-designed decision aids can support meaningful dialogue between patients and healthcare professionals by improving understanding of disease trajectory, treatment options, risks and benefits, and alignment of care with individual patient values and goals.

The Whole Foods Market Store Giving Program supports local communities by providing financial assistance to 501(c)(3) nonprofit organizations that focus on food access and environmental stewardship. This biannual program allows eligible organizations to apply via the Community Engagement Portal, although not all requests can be fulfilled due to high demand. Priority is given to those without recent funding, promoting sustainable community engagement.

The Anna Fuller Fund Grant provides year-round support for organizations dedicated to alleviating suffering caused by cancer. Established in memory of Egbert C. Fuller’s wife, the fund prioritizes applications that focus on cancer research and education initiatives. Eligible applicants must be 501(c)(3) organizations or equivalent charities outside the U.S. Grant funds cannot be used for direct treatment, ensuring that resources are allocated to research and public education.

The 1Fur1 Foundation Grant supports U.S.-based 501(c)(3) charities that engage in animal-assisted programs. Eligible organizations can apply for grants ranging from $500 to $7,500 to support Animal Assisted Therapy, Activity, and Service Dog programs. The foundation focuses on charities that align with its mission and does not fund individual requests, for-profit businesses, or initiatives that promote animal cruelty. Applications are reviewed within 90 days.

The Pathway to Stop Diabetes Initiator Award (INI) aims to support early career researchers in diabetes research by providing funding and mentorship. With a focus on innovative and transformational ideas, this initiative encourages researchers to develop groundbreaking solutions for diabetes prevention and management. The award offers up to $100,000 annually in Phase 1 and $325,000 in Phase 2, fostering a new generation of leaders committed to improving the lives of those affected by diabetes.

The Junior League of San Francisco (JLSF) offers Enabling Funds Grants to support nonprofit organizations in the Bay Area that address essential needs such as housing, food, and personal necessities. With grants up to $5,000, priority is given to those facing urgent financial challenges. Eligible organizations must align their programs with JLSF's mission and provide verification of their 501(c)(3) status. This initiative helps sustain vital community services and empower women’s leadership.

Arnold Ventures

Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of Americans through evidence-based policy solutions that maximize opportunity and minimize injustice. We focus on improving systems where outcomes are falling short, incentives are misaligned, and the time is right for change. To advance this mission, we invest in rigorous research to strengthen the evidence base on what works to improve outcomes for individuals, families, and communities, and to inform policy and practice at scale.

AV’s Higher Education team seeks to fund rigorous, causal research on programs, policies, and practices that improve student outcomes and deliver stronger returns on investment for students and taxpayers. Our work focuses on strengthening the evidence base on effective student success models and aligning policy and funding incentives to support their adoption and scale.

Causal Research to Improve Outcomes for Part-Time Students

Purpose of the RFP

This RFP seeks to fund rigorous causal research that builds the evidence base on effective programs and policies for part-time students and identifies scalable, cost-effective approaches to improve completion and labor market outcomes. Findings should generate actionable insights to inform institutional practice, system-level decision making, and state policy, with the goal of improving outcomes and maximizing return on investment for students and taxpayers.

Population of Interest

Because enrollment intensity is fluid, proposals do not need to limit eligibility to students who are enrolled part-time at baseline. Instead, studies should focus on interventions that primarily serve or are expected to meaningfully impact students who are more likely to enroll part-time, including:

• Adult learners (age 25+)
• Student parents and caregivers
• Working adults

Interventions may serve mixed-enrollment populations, so long as the proposed study is clearly designed to improve outcomes for these populations.

Bass Pro Shops & Cabela's Outdoor Fund supports conservation-focused nonprofits through fundraising events and donation of merchandise or gift cards. Organizations eligible for funding must be registered 501(c)(3) entities in the U.S. or provincially registered nonprofits in Canada. This initiative aims to connect communities to outdoor activities while promoting wildlife conservation and support for military veterans. Grants of up to $1,000 are available to enhance local fundraising efforts.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Stanley C. and Maxine G. Sutherland Scholarship

This scholarship has been made possible by the generosity of Stanley Sutherland, Jr., who established the Stanley C. and Maxine G. Sutherland Scholarship of the Community Foundation for Muskegon County. Education was important to Maxine Sutherland. She graduated from Muskegon Junior College in 1940, received her nursing degree from the Hackley School of Nursing in 1942, and continued her education over the years until she received a B.S. in Education from Western Michigan University. Nursing was also important to Maxine, and over the years she was employed by Hackley Hospital, Visiting Nurses, and the office of her brother, Dr. Griffith. In her memory, her husband, Stanley Sutherland, Jr., has established the Maxine G. Sutherland Memorial , a donor advised , which will assist Muskegon County residents to pursue careers in nursing and other health related fields as well as support other projects and programs that were equally important to her.

The FY26 Autism Research Program Career Development Award aims to support early-career investigators in conducting innovative research that can significantly impact autism. It encourages applications addressing specific areas of interest and mandates community collaboration for projects involving pilot clinical trials. Proposals must include partnerships with community members for effective planning and implementation, ensuring that the research is grounded in the needs of the autism community.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Sherman R. Poppen Scholarship

This scholarship has been made possible by the generosity of Sherman R. Poppen, who established the Sherman R. Poppen Scholarship of the Community Foundation for Muskegon County. Nancy Poppen was an artist who wanted children to explore and develop their talents in the fine arts. Prior to her death, in 1993, she established a fund in her name to provide "individualized arts opportunities" for Muskegon Public Schools students in grades three through 12. Her husband, Sherman Poppen, has watched the talents of over one hundred students develop over these last few years. Feeling the need to continue to support their talents, he established the Sherman R. Poppen Scholarship Fund to provide scholarships for Muskegon High School graduates who have participated in programs funded through the Nancy K. Poppen Fund. Now these students, pursuing arts studies at accredited colleges and universities or under the tutelage of master artists, can be assured of continued support and backing.

Santa Ynez Valley Foundation

Founded in 1991 by Stuart C. Gildred, Sr., the Santa Ynez Valley Foundation proudly supports programs and services that benefit the Santa Ynez Valley and Los Alamos communities. Our mission focuses on grant-making and active collaboration with nonprofits, community leaders, and grassroots projects to strengthen the social fabric of the region.

More than $7.5 million in grants has been awarded to nearly 300 local organizations, and scholarships have been awarded to 578 students pursuing higher education. By partnering with donors, we continue to fund grants and scholarships that strengthen nonprofits, empower students, and enrich community life. Every gift creates opportunities, fosters connections, and helps build a stronger, more vibrant community for all.

Santa Ynez Valley Foundation: Food Security Grant

The Santa Ynez Valley Foundation (SYVF) awards grants to organizations that are certified as tax-exempt under Section 501(c)(3) of the Internal Revenue Code and provide programs and services to people in the Santa Ynez Valley and Los Alamos.

SYVF supports organizations that do not discriminate in their delivery of programs and services based on race, color, religion, gender, national origin, ancestry, age, medical condition, disability, veteran status, marital status, sexual orientation, or any other characteristic protected by law. SYVF will consider projects from faith-based organizations, provided the projects are secular in nature and open to individuals of all faiths and/or those with no religious affiliation.

The Bayer Fund Health & Wellness Grant Program aims to support organizations that provide education and resources for patients and caregivers facing cancer and cardiovascular diseases. Grants focus on assisting communities, particularly the African American population, in managing these health issues. Funding covers educational services, disease awareness, and access to care, with all activities to commence post-funding decisions. Eligible organizations must hold a 501(c)(3) status and operate within 55 miles of Bayer sites.

NEXT for AUTISM's grants program empowers autistic adults by funding innovative initiatives across work, home, social engagement, and health & well-being. With over 380 funded projects nationwide, the program supports 501(c)(3) organizations in the U.S. First-time grantees can apply for up to $10,000, while returning grantees may request up to $25,000. The program emphasizes community-based solutions and aims to enhance the quality of life for autistic individuals.

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Rocket Scholars Foundation Scholarship

This scholarship has been made possible by the generosity of the parents and alumni of Reeths Puffer Schools, who established the Rocket Scholars Foundation Scholarship of the Community Foundation for Muskegon County. The Rocket Scholars Foundation was created by parents and alumni with two purposes in mind:

• To continue to foster within the school system a culture of rigorous academic achievement for all students and
• To offer those students who have demonstrated high achievement, scholarships to help defray the increasingly expensive tuition costs at colleges, universities and accredited post-secondary vocational and technical schools.

Rangeley Educational Fund

Fund provides scholarships to further the education of young men and women pursuing study in technical, vocational, academic, or professional fields.

Amount

$1,000+

The Small Business Transition Grant for New Entrepreneurs aims to support early-career scientists transitioning into entrepreneurship. Funded by the NIH and CDC, this initiative encourages small business concerns to apply for SBIR Phase I and Fast-Track grants. Key components include research funding, entrepreneurial training, and mentorship. Potential applicants are urged to prepare their projects and identify mentors, ensuring the inclusion of experienced personnel committed to the project. This opportunity is tailored for first-time Principal Investigators.

Brothers Helping Brothers is a 501c3 non-profit organization dedicated to providing essential tools and equipment to small and rural fire departments. Founded in 2014 after a tragic loss, the organization has raised over $20,000 to support fire services. They grant financial assistance to eligible fire and EMS organizations across the U.S. with a focus on enhancing safety and operational capability. Their mission continues to grow as they research and address the pressing needs of emergency services.

The Alice M. Ditson Fund supports recording projects that aim to document and promote the music of younger, lesser-known American composers. The fund prioritizes living composers of classical concert music, especially those in the early stages of their careers, while also recognizing established composers who deserve greater visibility. Eligible applicants include organizations with a fiscal sponsor or non-profit status, and projects must involve significant contemporary American music.