Best Operating Grants for Nonprofits in California

The Aerie Real Foundation™ Community Grant aims to enhance confidence, inclusion, and sustainability among young women while supporting non-profit organizations in the US and Canada. Grants of up to $10,000 are available to programs focused on mental well-being, fostering inclusive communities, and environmental protection. Applications are accepted from certified 501c3 nonprofits, with funding allocated for projects that align with the Foundation's mission. The goal is to empower the next generation and create a positive impact in local communities.

The KTGF Fellowship Programs, funded by the Klingenstein Third Generation Foundation, offer $100,000 over two years to support post-doctoral and junior faculty research on ADHD and depression in children, particularly from low-income and under-resourced backgrounds. This initiative aims to foster promising early-career scientists while producing impactful research that benefits affected children and families. Applications are accepted from September 1 to December 15, with specific eligibility criteria outlined for candidates.

About Pfizer External Research & Grants

Pfizer External Research & Grants (ER&G) supports independent research, education, and QI initiatives to improve patient outcomes in areas of unmet need. Competitive grants are awarded through transparent RFPs reviewed by independent expert panels.

About ASCP

American Society for Clinical Pathology (ASCP) is the world’s largest professional membership organization for pathologists and laboratory professionals, with more than 100,000 members. ASCP provides excellence in education, certification, and advocacy on behalf of patients and the laboratory workforce. With a portfolio of more than 900 educational activities, ASCP is the worldwide leader in providing CME/CMLE credit for the entire laboratory team.

Quality Improvement in Molecular Testing Pathways for Metastatic Colorectal Cancer (mCRC)

The American Society for Clinical Pathology (ASCP), in collaboration with Pfizer Inc. and with participation from the American Society of Clinical Oncology (ASCO, invites proposals for pathology-centric Quality Improvement (QI) initiatives aimed at optimizing molecular testing pathways in the management of metastatic colorectal cancer (mCRC). This grant opportunity seeks to fund sustainable projects that improve biomarker testing practices, strengthen targeted therapy selection, and support care teams in implementing patient-centered protocols. 

The overarching goal of this program is to advance diagnostic excellence and improve treatment decision-making for patients with mCRC.

The Mumford & Keller Grant and Scholarship Program, initiated by Indiana Audubon in 2010, offers financial support for projects focusing on natural resources and Indiana's birdlife. With grants ranging from $500 to $5,000, it aims to promote conservation, research, and education. Priority is given to initiatives targeting key species and habitats within Indiana. This program honors the legacy of Russell Mumford and Charles Keller, enhancing bird conservation efforts for future generations.

Patagonia’s Corporate Grant supports grassroots organizations focused on bold, direct-action campaigns that address the root causes of environmental issues. The program emphasizes equity, inclusivity, and long-term change, targeting communities affected by environmental exploitation. Grants are awarded to innovative groups within the US and Canada, fostering civic engagement and measurable objectives. Patagonia prioritizes funding for initiatives that confront systemic bias and promote environmental justice, ensuring that diverse voices are represented in the environmental movement.

The Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) aim to support clinical trials that can be completed within a limited timeframe. This funding opportunity encourages a variety of exploratory studies that align with the NIAMS mission, focusing on interventions such as drugs, biologics, devices, and various therapies. Applications are due by 5:00 PM local time of the applicant organization.

This funding opportunity encourages applications for clinical observational studies focused on musculoskeletal, rheumatic, and skin diseases. It aims to gather essential data for designing future clinical studies, enhancing understanding of disease symptoms, progression, and patient outcomes. Observational studies supported by this initiative will contribute to the development of objective biomarkers and effective outcome measures. Applicants are invited to address key challenges in clinical project design, ensuring a robust foundation for subsequent clinical trials.

The ASTR Targeted Research Area Grant supports projects by scholars focusing on under-represented areas in theatre, dance, and performance studies. This includes research on Asian, African, Latin American, and Middle Eastern disciplines, as well as pre-1900 studies and essential translations. The grant, offering up to $3000, encourages recipients to publish their findings and collaborate with Theatre Survey editors. Eligibility extends to scholars with terminal degrees and graduate students, provided they are ASTR members.

The AWWA Jacobs Holly A. Cornell Scholarship, established in 1990, supports graduate students pursuing water supply and treatment studies. Sponsored by Jacobs/CH2M, this $10,000 scholarship is aimed at first-generation college graduates or those who have faced economic disadvantages and significant educational barriers. AWWA, the largest organization of water supply professionals, emphasizes the importance of investing in the future of the water industry through such scholarships.

The Eastern Bank Foundation (EBF) is dedicated to empowering communities through its Neighborhood Donations initiative. By investing over $16 million in local organizations, EBF aims to support vital services and promote equity in Eastern Massachusetts, Southern New Hampshire, and Rhode Island. This program allows contributions to non-501(c)(3) organizations, reinforcing EBF's commitment to partnership and community-driven solutions, with donations typically ranging from $100 to $1,000.

The Goldberg, Joseph and Ruth Scholarship, offered by the Beatrice Educational Foundation, aims to support students pursuing medical professions, such as nursing, dental, and physical therapy. Established in 1987, the Foundation provides over $55,000 annually in scholarships to Beatrice High School seniors. Eligible applicants must be in the top quarter of their class and complete the application independently. This scholarship is part of the Foundation's commitment to enhancing educational opportunities in the Beatrice School District.

Common Waters: Strengthening Community-based Coastal and Riverine Stewardship

Opportunity Overview

Projects supported by this RFP must be community-based stewardship initiatives (including but not limited to stewardship driven by Indigenous and descendant communities); they should be led by an individual with a strong connection to and/or an existing track record of work in the community(ies) where the project will take place, or by a member of the community themselves, and be designed in response to community needs. Projects can focus on a wide range of specific issues, including (but not limited to) local conservation and ecosystem restoration, climate change adaptation and resilience, or sustainable fishing/agriculture. The RFP will prioritize projects in National Geographic-Lindblad Expeditions destinations, including the Arctic, Asia, Baja California, Costa Rica and Panama, Europe and the Mediterranean, Patagonia, the Peruvian Amazon, the Pacific Northwest, Southeast Alaska and British Columbia, the South Pacific, and the United Kingdom and Ireland. For more detailed information on targeted areas within these regions, please refer to the targeted areas document.

The Science Policy Fellowship, offered by the American Chemical Society, provides a unique opportunity for trained scientists to engage in public policy. This program enhances understanding of the policy-making process, allowing Fellows to work alongside experienced Government Affairs staff. The Fellowship focuses on key areas such as federal research funding, education in STEM, and environmental policies. Candidates with a strong background in chemical sciences or engineering are encouraged to apply, regardless of holding a doctorate.

The John Muir Community Health Fund (CHF) Grant focuses on enhancing health care access for underserved populations in Central and East Contra Costa County. As part of John Muir Health's commitment to improving community well-being, the CHF provides financial support to nonprofit organizations addressing critical health needs. By fostering innovative health initiatives and filling service gaps, the grant aims to create lasting health improvements and ensure equitable care for vulnerable groups.

The BTCF: Simple Gifts Fund Grant supports young artists aged 13-19 in the Berkshire Taconic region, providing financial assistance for summer enrichment programs in the arts. Established in 1998 in memory of folk singer Bill Crofut, the fund aims to empower youth through small grants that can cover costs for tuition, art supplies, or living expenses. The grant fosters creativity and personal growth, ensuring that young individuals have opportunities to pursue their passions.

The Richard King Mellon Foundation invites innovative proposals that align with their 2021-2030 Strategic Plan, aiming to invest over $1.2 billion to enhance opportunities in southwestern Pennsylvania. Their funding focuses on conservation, economic development, economic mobility, health and well-being, organizational effectiveness, and social-impact investments. The General Application offers flexibility without deadlines, allowing for a variety of support types, including project-specific and general operating funding, aimed at enriching community vitality and environmental stewardship.

The Arthritis National Research Foundation supports early career researchers in their quest to advance understanding and treatment of arthritis and related autoimmune diseases. Annually, the foundation grants 10 to 20 awards of $125,000 each for two years. Focus areas include osteoarthritis, rheumatoid arthritis, lupus, and more. Eligible investigators must hold an M.D. or Ph.D., be affiliated with a U.S. nonprofit research institution, and commit significant research time. Applications from prior grant recipients or those with certain NIH grants are ineligible.

The AWWA Scholarship Program, specifically the Woodard & Curran Scholarship, offers a $5,000 merit-based award annually to undergraduate or graduate students focused on water-related fields. This initiative aims to support historically marginalized communities, including women and BIPOC students, promoting equity in the water industry. With clean water being essential for community health, this scholarship reflects AWWA's commitment to nurturing the next generation of water professionals.

The Loye and Alden Miller Research Award, presented by the American Ornithological Society, recognizes lifetime achievements in ornithological research. It honors the legacy of Loye Holmes Miller and his son Alden Holmes Miller, who significantly contributed to the field and mentored numerous students. This prestigious award aims to uphold high ethical standards in ornithology and is open to current AOS members, promoting a diverse and supportive community in bird conservation.

The Loretta Morris Memorial Grants support individuals with cystic fibrosis in California who wish to engage in physical activities such as swimming, horseback riding, dance, or golf. Established in memory of Loretta Morris, this fund aims to help recipients enjoy the benefits of an active lifestyle. Applications are welcomed from both children and adults, promoting inclusivity and well-being within the CF community. Note that certain items, like memberships or accessories, are not eligible for funding.

The T32 Postdoctoral Fellowship in Mental Health Services Research is a two-year program supported by the National Institute of Mental Health. It trains emerging researchers in health systems research focusing on mental health and suicide prevention. The fellowship emphasizes mentorship, research methods, and professional development, preparing fellows to secure independent funding. Candidates with PhDs, MDs, or equivalent degrees, especially those from underrepresented backgrounds, are encouraged to apply. More information is available through the program's website.

Mary Kay Ash Foundation

Guided by Mary Kay Ash’s dream to enrich the lives of women everywhere, the Mary Kay Ash Foundation® raises and distributes funds to invest in breakthrough cancer research and clinical trials to find a cure for women-related cancers and ending domestic violence.

Since 1996, the Mary Kay Ash Foundation®, a 501(c)3 organization, has contributed more than $100 million to organizations aligned with its two-fold mission. In addition, the Foundation supports awareness initiatives, community outreach programs, and advocates for legislation to ensure women are healthy and safe. Through our global charitable foundations in Brazil, Canada, China and the United States, we are collectively making a deeper impact on the lives of women around the world.

Mary Kay Ash Foundation: Cancer Research Grant

The Mary Kay Ash Foundation is a non-profit public foundation, which focuses on funding research for innovative grants for translational research of cancers affecting women (ovarian, uterine, breast, endometrial or cervical cancer among others). Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer. Each year the Foundation extends invitations to NCI designated cancer institutes and accredited medical schools to apply. Only one application is accepted per institution.

Grant proposals are reviewed by a Scientific Research Review Committee comprised of notable members of the American medical and scientific community. Grants are awarded up to $100,000 (combined direct and indirect costs) for a two-year period. The Foundation anticipates funding between 10 and 15 grants annually. 

The Affirm Cares Employee Foundation Grant, established by Affirm, aims to support non-profit organizations making a significant impact in financial literacy, community enrichment, and technology education. Grants range from $1,000 to $10,000, focusing on sustainable initiatives that empower communities and alleviate housing insecurity. Eligible applicants must be 501(c)(3) designated non-profits operating within the U.S. The foundation prioritizes measurable outcomes in its funding efforts, fostering civic engagement and vibrant communities.

The Marion Jenkinson Service Award, presented by the American Ornithological Society, honors early- and mid-career ornithologists for their extensive volunteer contributions and service to the society. This award includes a framed certificate and recognizes individuals who exemplify high ethical standards aligned with the AOS Code of Conduct. The award aims to foster a diverse and supportive ornithological community while promoting bird conservation and scientific study.

The Pasadena Audubon Society offers research grants aimed at supporting students and community organizations engaged in bird-related research and conservation. This funding is focused on projects relevant to Southern California and the Pacific Flyway, encouraging scientific studies and community initiatives that enhance our understanding and protection of avian species.

Wilson Ornithological Society

The earliest stages of the Wilson Ornithological Society’s development began with the formation of the “Young Ornithologists’ Association,” initiated in 1886 under the leadership of L. O. Pindar and J. B. Richards. They began as a corresponding group of naturalists interested in birds, with notes published in The Oölogist.

Soon after, the Society acquired a constitution and established itself in December 1888 as the Wilson Ornithological Chapter of the Agassiz Association. The fledgling group was named in honor of Alexander Wilson, considered the Father of American Ornithology. Its original purpose was “the study of birds, their nests, and eggs.”

Over the subsequent decades, the group—eventually becoming known as the Wilson Ornithological Club—published its proceedings and articles under a series of diverse titles, culminating in The Wilson Bulletin after 1894 and, most recently, The Wilson Journal of Ornithology. The Club adopted its Constitution and Bylaws in 1930 and became the Wilson Ornithological Society in 1955.

Early Professional Avian Conservation and Community Impact Award

The Early Professional Avian Conservation and Community Impact Award recognizes outstanding contributions by Wilson Ornithological Society (WOS) members working in applied, non-research careers that advance the conservation of birds and their habitats. This award also celebrates professionals whose work fosters a stronger and more inclusive conservation community, through management, education, communication, advocacy, or community engagement.

Purpose

This award highlights the diverse pathways through which people contribute to lasting ornithology and avian conservation beyond academic research. It honors those whose efforts build bridges between science, management, and the public; inspire action for birds; provide mentorship or leadership to build capacity; and promote equity, inclusion, and accessibility within the bird conservation community.

Examples of Qualifying Contributions

• Developing and implementing habitat management or conservation plans.
• Creating tools, educational materials, or outreach programs that promote bird conservation.
• Leading advocacy, communications, or storytelling that inspires conservation action.
• Building partnerships or community engagement initiatives that strengthen conservation impact.
• Advancing conservation policy or planning at local, regional, or national scales.

Award and Presentation

The recipient will be recognized at the 2026 Wilson Ornithological Society Annual Meeting, where they will be invited to share their work with attendees. The award includes:

• A monetary honorarium
• An original piece of artwork from an early-career artist
• Coverage of meeting registration, travel, lodging, and per diem expenses

The Lasher-Bottorff Award, established by the American Association of Avian Pathologists, recognizes outstanding contributions to poultry health. It honors Dr. Hiram N. Lasher and Dr. C. A. Bottorff, pivotal figures in avian medicine. The award, valued at $1,000, is presented annually to a veterinarian who has made significant advancements in avian diagnostics or technical services over the past decade, promoting the health and productivity of poultry in North America.