Best Foundation Grants for Nonprofits in Colorado

The Therapeutic Giving program from Johnson & Johnson Innovative Medicine aims to support local and regional organizations focused on improving patient access to treatment and advancing health equity. Eligible applicants include 501(c)(3) nonprofit organizations, with funding preferences for programs that address significant healthcare disparities, mental health initiatives, and innovative solutions with measurable outcomes. The application period for local organizations runs from March 1 to May 31, while national organizations can apply in September.

The Therapeutic Giving initiative by Johnson & Johnson focuses on funding programs in neuroscience aimed at enhancing patient access to treatments and promoting health equity. Nonprofit organizations classified as 501(c)(3) can apply for support from March 1 to May 31. The initiative emphasizes innovative, measurable programs in areas like Alzheimer’s disease and mental health, prioritizing those that address healthcare disparities and improve quality of life for affected individuals.

The U.S. Healthcare Donations program by Amgen aims to support not-for-profit organizations in the healthcare sector. As a leading biotechnology company, Amgen provides funding for initiatives that improve science, technology, education, and public awareness on medical conditions. Organizations eligible for funding must be tax-exempt entities, focusing on genuine philanthropic efforts that align with Amgen's mission to enhance health outcomes and reduce the burden of diseases.

The Bellco Foundation Community Giving Grant supports initiatives in Financial Education, Quality of Life, and Arts & Culture. Focused on impactful contributions, Bellco aims to empower communities through partnerships with organizations like EconLitCO and Food Bank of the Rockies. The grant prioritizes requests from 501(c)(3) organizations aligned with Bellco's business objectives while excluding typical fundraising events and political affiliations. Applications must be submitted at least 90 days prior to events.

The Entergy Charitable Foundation Grant focuses on supporting initiatives that foster thriving communities through education, poverty solutions, and environmental programs. The foundation prioritizes funding for 501(c)(3) organizations and similar entities. Key areas include education development, innovative poverty solutions, and environmental restoration efforts, such as coastal wetland preservation. Organizations are encouraged to apply at least three months before funding is needed, ensuring timely support for impactful community projects.

The CSHF: Fostering Collaboration Grant Opportunity encourages innovative partnerships among diverse organizations to tackle complex community health challenges in El Paso and Teller Counties, Colorado. This grant prioritizes collaborative efforts that align with the Foundation's focus areas, including healthcare access and trauma prevention. Applicants must demonstrate commitment to evidence-based practices and transformative potential. Engaging with CSHF staff prior to application is essential for consideration.

The Rural Initiative Grant Program by the Laura Jane Musser Fund aims to foster collaboration among rural communities in areas like economic development and education. Emphasizing community involvement, it encourages diverse participation and measurable outcomes within 18 months. Grants of up to $25,000 for implementation or $5,000 for planning are available, targeting nonprofit organizations and local governments in select states. This initiative seeks to empower communities to achieve positive change through active engagement and support.

Reiter Family Foundation Grant

The Reiter Family Foundation seeks to support organizations that are doing meaningful work to shape and sustain Colorado communities. Our areas of focus are housing and food security, education and youth programming, and environment and conservation, but we do welcome inquiries from non-profits who do not necessarily fit neatly into our focus areas. In terms of geographic location, we tend to focus our giving in the Denver Metro and Grand County areas of Colorado.

Environment and Conservation

Environment/Conservation: With our family roots in this beautiful state, we want to support the protection and conservation of our Colorado’s lands and waterways as well as help to cut down on the pollution that threatens the health and longevity of our planet as a whole. 

Grants typically range from $2,000 - $15,000, but additional funding may be available.

Applicants can only submit one grant proposal each calendar year (January - December), but may apply again the following year unless otherwise advised. 

The Title XVI Water Reclamation and Reuse Projects, funded by the US Department of the Interior's Bureau of Reclamation, invites proposals for innovative water reuse solutions. This program enhances water supply reliability and supports sustainable practices for urban and agricultural communities. By leveraging Federal and non-Federal resources, the initiative aims to address water scarcity and improve hydropower reliability, aligning with national priorities for energy and resource management.

The WNAN Natural History Research Grant supports research in biological natural history within western North America. Grants of up to $2,500 are available for five authors to assist with travel, supplies, and other research-related expenses. This initiative particularly encourages applicants from institutions where research is not the primary focus, aiming to foster diverse contributions to natural history.

The Strengthening Families and Communities Grant by Telligen Community Initiative focuses on enhancing the resilience of youth and families through community-based funding. This initiative is transitioning to two-year funding periods, with applications due in March and October for different states. The grant aims to address social determinants of health, providing targeted support based on extensive applicant feedback. The program emphasizes a narrowed applicant pool to ensure more consistent funding for impactful projects.

The Maine Cancer Foundation is seeking proposals for cancer screening initiatives aimed at early detection and prevention. This RFP focuses on screenings for breast, cervical, colorectal, lung, prostate, and skin cancers. Proposals should align with evidence-based practices endorsed by the CDC and U.S. Preventive Services Task Force. Interested applicants are encouraged to consult with MCF prior to submission to discuss project concepts and receive feedback on draft applications.

The Thornton S. Glide, Jr. and Katrina D. Glide Foundation provides grants to qualified 501(c)(3) organizations in California that focus on animal protection, land conservancy, agriculture, and civic endeavors. Established in 1995, the foundation prioritizes grants for specific capital acquisitions and does not support operational costs or direct aid to individuals. Emphasizing local impact, California-based organizations are favored over out-of-state counterparts.

The Colorado Forest Legacy Grant Program, administered by the Colorado State Forest Service, aims to protect vital private forest areas from conversion to non-forest uses. By focusing on conservation easements, the program promotes sustainable forestry practices and preserves significant ecological habitats. It encourages public and private partnerships to maintain forest integrity while allowing landowners to retain ownership. Priorities include reducing land fragmentation and safeguarding water quality, wildlife habitats, and unique ecological zones.

The Buell Foundation Grant supports organizations that enhance children's education and development in Colorado. Focused on underserved communities, it prioritizes early childhood programs, evaluations, and quality improvements. Grants typically range from $10,000 to $50,000, directing funds to those committed to impactful initiatives. Applicants must be 501(c)(3) organizations or government entities with a dedication to non-discrimination and community engagement. The foundation aims to create sustainable support for programs that foster positive outcomes for children.

The U.S. Geological Survey (USGS) is offering a funding opportunity to a CESU partner for research utilizing data from the Surface Water and Ocean Topography (SWOT) mission. This project aims to enhance hydrologic decision-making by providing low-latency water resource monitoring data across over 1 million locations in the U.S. It promotes collaboration between USGS and CESU researchers to improve data accuracy and automate water surface elevation publication, benefiting scientists and resource managers.

The Projects Bill Grants, authorized by the Colorado Water Conservation Board, address statewide water supply needs through investments ranging from $1 to $10 million. Eligible projects include water management, habitat conservation, and feasibility studies. These grants require matching funds and are aimed at significant regional impacts. Projects must demonstrate a clear need and can be proposed by any public or private entity capable of contracting with the state. Ineligible projects include those that can be completed without state funding.

The WaterSMART: Desalination Construction Projects initiative by the Bureau of Reclamation aims to enhance water supply reliability through cooperative funding and support for desalination facilities. This program aligns with federal priorities to improve energy and resource management, encouraging proposals that diversify local water sources. By focusing on innovative solutions to water scarcity, the initiative promotes sustainable water management practices, especially for growing communities facing water shortages.

The AdvoCare Foundation, established in 1993, aims to promote health and wellness for children through its grant program. Focused on year-round initiatives, the foundation supports local communities where AdvoCare distributors operate. Grants typically last one year with an average funding of $25,000, although multi-year support may be available. The foundation prioritizes programs that foster positive health changes and encourages collaborative efforts with previous grantees.

The Larry H. & Gail Miller Family Foundation offers General Operating Grants aimed at 501(c)(3) nonprofits that serve the west side of Salt Lake City. Grants of up to $10,000, with an average of $5,000, support initiatives in health, shelter, education, economic self-reliance, and cultural enrichment. Applications are reviewed monthly. Organizations must be registered as nonprofits and align with the Foundation's focus areas to be eligible for funding.

The WKKF Grant, offered by the W.K. Kellogg Foundation, is dedicated to fostering a future where every child and family thrives. With a focus on nurturing early education, accessible healthcare, and equitable food systems, this grant supports initiatives that empower communities across the U.S. and parts of Mexico and Haiti. Organizations meeting IRS regulations and being legal entities, particularly 501(c)(3) nonprofits, are encouraged to apply for funding to create lasting impacts in their communities.

The NACD Technical Assistance Grants program, in partnership with NRCS, has been enhancing conservation district support since 2018. By funding staff hires, it aims to improve service for agricultural producers and address conservation workload challenges. The initiative focuses on outreach, education, and civic engagement to empower local communities, promote sustainability, and support historically underserved producers in implementing conservation practices, thereby fostering both individual and community resilience.

The WaterSMART Applied Science Grants aim to enhance water management and supply reliability through innovative research and data utilization. By inviting qualified entities to apply for funding, the program focuses on improving hydrologic data access, forecasting capabilities, and modeling tools. This initiative aligns with federal priorities to optimize resources, ensuring water managers can effectively address future demands and adapt to climate challenges, thus fostering resilience in water operations across the nation.

Aid to Agencies

About the Program

The Arapahoe County Aid to Agencies (A2A) Program provides financial support to nonprofit organizations delivering essential services to Arapahoe County residents. Established in 2008 by the Arapahoe County Board of County Commissioners, the program was created to address critical community needs through strategic partnerships with local nonprofit providers.

Since its inception, the program has awarded more than $30 million to nonprofits serving residents across the county. 

For the 2026–2027 funding cycle, approximately $3,079,500 in General Fund support will be available, including designated allocations for safety net providers. 

In 2025, the program framework was updated to align with Arapahoe Forward and strengthen transparency, accountability, measurable outcomes, and alignment with community-identified needs. The updated framework prioritizes investments that address documented service gaps and improve quality of life for Arapahoe County residents.

Safety net providers are nonprofit organizations that deliver essential services to vulnerable or underserved populations. These organizations are typically distinguished by one or more of the following: 

• Serving as the sole or primary provider of a critical service  
• Offering services that do not duplicate existing County programs  
• Addressing high-need and high-impact service areas with demonstrated community demand  

Organizations currently designated as safety net providers: 

• Three Birds Alliance (formerly Gateway Domestic Violence Services)  
• Aurora Mental Health Center & Recovery – Detox Services  

These organizations receive direct base funding outside of the competitive application pool.

The Sunstate Equipment Foundation Grants support local charities focused on disadvantaged individuals, medical aid, housing assistance, domestic violence awareness, military and veterans' assistance, and care for abused animals. Founded in 2015, the foundation is a 501(c)(3) nonprofit that matches employee contributions dollar for dollar, reinforcing its commitment to community support and engagement. Charities in good standing can apply once every 12 months, fostering impactful initiatives where Sunstate operates.

The Kosciuszko Foundation offers Tuition Scholarships for American students of Polish descent pursuing graduate studies in the U.S. Scholarships can provide up to $12,000 for full-time studies, including master's and Ph.D. programs. Eligible applicants must be U.S. citizens or legal residents with Polish heritage and maintain a minimum GPA of 3.0. This program aims to foster educational exchanges and cultural understanding between the U.S. and Poland, supporting various fields of study.

The Levin Family Foundation Grant supports nonprofits focused on critical issues in Montgomery County, Ohio, such as the opiate epidemic, human trafficking, anti-bullying, and suicide prevention. Established in 1996, the foundation has invested over $12 million globally, emphasizing projects that align with its mission. Eligible organizations must be IRS 501(c)(3) tax-exempt. Priority is given to initiatives in the Greater Dayton Area, fostering positive community impact.