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Best Cuyahoga County Grants for Nonprofits in Ohio

Discover active funding opportunities in Cuyahoga County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Franklin County, Hamilton County, and Summit County.

9,000+

Available grants

$2.63B

Total funding

$5K

Median grant

9,000+ grants
$2.63B total
$5K median

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9,473 Results based on applied filters

Immune Drivers of Autoimmune Disease

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Immune Drivers of Autoimmune Disease (IDAD) network, supported by NIAID, aims to uncover early triggers and mechanisms of autoimmunity to prevent disease. Key initiatives include developing predictive tools and biomarkers, fostering preclinical cohorts, and utilizing AI and big data. The network will leverage shared infrastructure for collaborative research, managed by the IDAD Network Coordinating Center, which ensures coordination and resource sharing among awardees. This initiative is crucial for advancing understanding and prevention of autoimmune diseases.
Immune System Diseases Preventative Healthcare Emerging Technology Development

NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed) (363939)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $80,000
The NLM Grants for Scholarly Works in Biomedicine and Health (G13) program invites applications to support the creation of book-length manuscripts and scholarly works that are vital for U.S. health professionals and scientists. This initiative aims to foster critical reviews and analytical syntheses that enhance understanding of biomedical and public health challenges, ultimately contributing valuable resources for education, research, and clinical practice.
Health & Medicine Epidemiology & Public Health

LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The LAST MILE program, initiated by the NIAID, aims to enhance the implementation and effectiveness of HIV prevention and treatment strategies through real-world effectiveness trials. By fostering collaborations and focusing on diverse populations, this initiative seeks to translate clinical findings into practical applications. The program supports research across various disciplines, aligning with the NIH's mission to improve HIV/AIDS outcomes and address associated comorbidities. This multifaceted approach promises to bridge the gap between clinical trials and community-based interventions.
Epidemiology & Public Health Infectious & Parasitic Diseases Health Care Access & Delivery +1 more

Continuation of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) (U24 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Aging (NIA) is announcing a funding opportunity to support the Exceptional Longevity Data Management and Coordinating Center (EL DMCC). This initiative aims to enhance the management of large, diverse datasets and facilitate collaborative research across NIA projects. Core functions include data integration, AI/ML infrastructure development, and maintaining the ELITE Portal for secure data access. This NOFO encourages innovative approaches to longevity research, though applications are not currently being solicited.
Biology Genetics & Genomics Emerging Technology Development

Partnerships for Advancing Development of Diagnostics for Infectious Diseases

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Allergy and Infectious Diseases (NIAID) aims to enhance the development of diagnostic tests for infectious diseases through strategic partnerships between academia and industry. By fostering collaborations, NIAID seeks to overcome barriers to commercialization, ensuring promising diagnostics reach the market effectively. This initiative aligns with NIH's mission to advance innovative technologies that improve treatment and prevention strategies for infectious diseases, ultimately contributing to public health advancements.
Infectious & Parasitic Diseases Emerging Technology Development Allergies & Allergic Diseases

Mesara Family Foundation Grant

Mesara Family Foundation
Private
United States
Unspecified amount

About

Originally conceived by Dr Bruce Mesara in 1990 as a means to carry on his philanthropic efforts beyond his lifetime, the Mesara Family Foundation was re-envisioned by his two children Amy and Douglas in 2014, and received their 501(c)(3) status from the IRS in 2015. Amy and Douglas sought out the assistance of their cousins to build upon the charitable principals on their parents, aunts and uncles.

The foundation is headquartered in Kalamazoo Michigan.

Mission

The mission of the Mesara Family Foundation is to honor the philanthropic principles of the Mesara and Pauch families by supporting carefully selected organizations that share similar values. Our focus is to provide support toward education, conservation and other causes of special family interest where our funding will make a genuine difference.

Education Environmental Conservation

BJA FY 2026 John R. Justice (JRJ) Formula Grant Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BJA FY 2026 John R. Justice Formula Grant Program offers loan repayment assistance to local and state prosecutors and public defenders who commit to three years of service. Administered by state agencies, this program aims to alleviate the financial burden on legal professionals dedicated to public service. Applications are due by November 10, 2026, providing a crucial opportunity for eligible beneficiaries to secure support for their educational loans.
Crime & Justice Legal Services

OJJDP FY 2026 Juvenile Drug Treatment Court Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The OJJDP FY 2026 Juvenile Drug Treatment Court Program aims to enhance juvenile drug treatment courts (JDTCs) across the U.S. by supporting states, local courts, and Tribal governments. This initiative focuses on improving outcomes for youth dealing with substance use disorders or co-occurring mental health issues. The program underscores the commitment of the Office of Justice Programs to strengthen community safety and provide vital resources for effective intervention and support.
Mental Health & Psychiatric Diseases Youth Services Crime & Justice +1 more

OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $1,200,000
The OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance program aims to enhance the ability of state, Tribal, and local agencies to effectively address cases of missing and exploited children. This initiative will support multidisciplinary teams, including law enforcement and child protection personnel, to improve investigations and prosecutions. By providing essential resources and training, the program seeks to strengthen responses to protect vulnerable children and combat related public safety issues.
Youth Services Crime & Justice Crime Victim Services

OJJDP FY 2026 Community and Schools Youth Drug Prevention Program

US Department of Justice: Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The OJJDP FY 2026 Community and Schools Youth Drug Prevention Program aims to combat youth substance use through comprehensive prevention strategies. This initiative invites applications from states, local governments, and nonprofit organizations to develop programs that educate and support youth in schools and community settings. By fostering collaboration with law enforcement and community coalitions, the program seeks to build capacity and implement effective interventions to protect the well-being of American youth.
Youth Services Addiction & Substance Use Disorders Preventative Healthcare

Fiscal Year (FY) 2027 Department of War (DoW) Multidisciplinary Research Program of the University Research Initiative (MURI)

US DOD: Dept. of the Air Force, Materiel Command
Federal Government
American Samoa, Guam +4 more
Up to US $15,000,000
The FY 2027 Department of War Multidisciplinary Research Program of the University Research Initiative (MURI) aims to fund U.S. academic teams conducting innovative research to tackle complex challenges for the Department of War. Established in 1985, MURI promotes collaboration among diverse scientific disciplines, enhancing the defense workforce and addressing critical areas of interest through multidisciplinary research efforts at U.S. universities.
Engineering Education - Higher Education Science +1 more

BJA FY 2026 National Center for Veterans Justice

Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $4,000,000
The BJA FY 2026 National Center for Veterans Justice aims to enhance support for veterans in the criminal justice system. By providing specialized training and resources to law enforcement and service providers, the center will address critical gaps in veteran identification and coordination among agencies. This initiative seeks to improve outcomes for veterans experiencing issues like PTSD and military sexual trauma, ultimately strengthening public safety and ensuring effective responses to their unique needs.
Military & Veterans Services Mental Health & Psychiatric Diseases Crime & Justice

BJA FY 2026 Paul Coverdell Forensic Science Improvement- Competitive Grants Program

US Department of Justice: National Institute of Justice (NIJ)
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The BJA FY 2026 Paul Coverdell Forensic Science Improvement- Competitive Grants Program aims to enhance forensic science and medical examiner/coroner services across the U.S. This funding opportunity supports state and local government laboratories in improving their capabilities to ensure justice and public safety. Applications are due by November 5, 2026, at 8:59 p.m. ET, promoting advancements in forensic practices to better serve law enforcement and communities.
Crime & Justice Community / Public Safety

BJA FY26 Paul Coverdell Forensic Science Improvement - Formula Grants Program

US Department of Justice: National Institute of Justice (NIJ)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BJA FY26 Paul Coverdell Forensic Science Improvement - Formula Grants Program supports state agencies in enhancing forensic science capabilities. The program aims to improve public safety by funding initiatives that strengthen forensic science and support law enforcement efforts. Eligible applicants can submit their full applications through JustGrants by November 6, 2026. This funding is crucial for addressing ongoing challenges in the justice system, including violent crime and public safety concerns.
Crime & Justice Community / Public Safety

OJJDP FY 2026 Multistate Mentoring Programs

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
US $1,000,000 - US $4,000,000
The OJJDP FY 2026 Multistate Mentoring Programs aims to provide crucial mentoring services to at-risk youth, helping them avoid delinquency and victimization. This funding opportunity emphasizes the importance of one-on-one, group, and peer mentoring approaches. The program aligns with the U.S. Department of Justice's commitment to public safety and juvenile justice reform, addressing the needs of vulnerable populations and fostering positive youth development.
Youth Services Crime & Justice Youth Development & Leadership +1 more

OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC) Technological Investigative Capacity

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $675,000
The OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC) program aims to enhance the technological investigative capacity of ICAC task forces nationwide. Through this funding opportunity, the program will support the development and refinement of investigative tools and methods to combat child sexual abuse material, exploitation, and trafficking. The deadline for application submission is November 5, 2026, at 8:59 p.m. ET, emphasizing the urgency of addressing these critical issues.
Crime & Justice Human Trafficking Crime Victim Services +1 more

Fiscal Year (FY) 2027 Department of War (DoW) Multidisciplinary Research Program of the University Research Initiative (MURI) (363905)

US DOD: U.S. Army Materiel Command
Federal Government
American Samoa, Guam +4 more
Up to US $7,500,000
The FY 2027 Department of War Multidisciplinary Research Program (MURI) funds U.S. academic teams engaged in innovative basic research addressing future defense challenges. Established in 1985, MURI emphasizes collaboration across multiple scientific disciplines to tackle complex, DoW-relevant issues. By fostering partnerships among faculty, postdoctoral researchers, and students, the program aims to advance the U.S. defense industrial base and nurture a skilled scientific workforce, contributing to significant breakthroughs in military technology and economic growth.
Engineering Science Workforce Preparation & Job Readiness +1 more

OJJDP FY 2026 Victims of Child Abuse Act Training and Technical Assistance for Child Abuse Professionals

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $2,850,000
The OJJDP FY 2026 Victims of Child Abuse Act Training and Technical Assistance program aims to enhance the skills of child abuse professionals. This initiative will promote coordinated investigations and improve intervention strategies for child abuse victims. By providing essential training on effective interviewing, investigative techniques, and interagency collaboration, the program seeks to elevate the quality of care and support available to affected children and families. Applications are due by November 5, 2026.
Youth Services Crime & Justice Crime Victim Services

BJA FY 2026 Rural Violent Crime Reduction Initiative

Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The BJA FY 2026 Rural Violent Crime Reduction Initiative aims to empower local law enforcement in rural areas to combat violent crime effectively. This funding opportunity provides resources for personnel, technology, and data analytics to enhance crime prevention strategies. Eligible applicants can utilize updated equipment and training to address specific violent crime challenges, ensuring safer communities through innovative approaches and strategic resource allocation. Applications are due by November 6, 2026.
Crime & Justice Rural Development Community / Public Safety +1 more

Fiscal Year (FY) 2027 Department of War Multidisciplinary Research Program of the University Research Initiative (MURI)

US DOD: Dept. of the Navy, Office of the Chief of Naval Research
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Fiscal Year 2027 Department of War Multidisciplinary Research Program aims to fund innovative research teams from U.S. universities. Established in 1985, this initiative addresses complex challenges faced by the Department of War, fostering collaboration across various scientific disciplines. By integrating world-class faculty and graduate students, the program seeks to cultivate a skilled workforce poised to enhance the U.S. defense capabilities and contribute to the advancement of the defense industrial base.
Engineering Education - Higher Education Science +1 more

BJA FY 2026 Students, Teachers, and Officers Preventing (STOP) School Violence Program

US DOJ: Office of Justice Programs
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The BJA FY 2026 Students, Teachers, and Officers Preventing (STOP) School Violence Program aims to enhance school safety by funding initiatives that train staff and students, develop threat assessment teams, and implement technology solutions like anonymous reporting systems. This program supports effective strategies to identify and mitigate risks of school violence, ensuring students have the tools necessary to foster a secure learning environment while adhering to the guidelines set forth by the STOP School Violence Act.
Community / Public Safety Violence Prevention School Safety +1 more

State Biomonitoring Cooperative Agreement

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $750,000 - US $900,000
The State Biomonitoring Cooperative Agreement aims to enhance public health laboratories' ability to conduct biomonitoring and assess human exposure to environmental chemicals. This funding opportunity emphasizes community investigations, state-level studies, and emerging chemicals not covered in the National Exposure Report. By improving laboratory capacity and fostering collaboration, the initiative seeks to identify harmful exposures and evaluate intervention effectiveness over a three-year period.
Epidemiology & Public Health Environmental Contamination & Pollution Environmental Health

Research to Improve Rigor, Replicability, and Reproducibility in Biomedical and Behavioral Sciences

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Neurological Disorders and Stroke (NINDS) is collaborating with other NIH institutes to enhance rigor and replicability in biomedical and behavioral research. This initiative aims to support projects focused on assessing the impact of improved research practices, developing frameworks for study selection, and measuring the generalizability of findings. Currently, applications are not being solicited, allowing researchers time to prepare collaborative proposals.
Neurological Diseases & Disorders

John H. Prescott Marine Mammal Rescue Assistance Grant (363929)

DOC NOAA - ERA Production
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The John H. Prescott Marine Mammal Rescue Assistance Grant supports the recovery and care of sick or injured marine mammals through federal assistance to the U.S. National Marine Mammal Stranding and Entanglement Response Networks. Eligible applicants must provide a Prescott Letter of Eligibility, confirming their participation in the network. This program aims to enhance marine mammal health monitoring and response capabilities across the country, ensuring timely and effective interventions for stranded marine life.
Wildlife Management Marine / Ocean Conservation Environmental Health

Marion Women’s Business Council Scholarship

Marion Community Foundation
Private
United States
Unspecified amount

About Marion Community Foundation

Since 1998, area residents have been turning to Marion Community Foundation to make their philanthropic giving as effective as possible. We are a public charity serving thousands of people who share a common concern … improving the quality of life in Marion County.

Individuals, families, businesses and organizations create permanent charitable funds that help our community meet its needs and challenges. The Foundation invests and administers these funds.

Marion Women’s Business Council Scholarship

The Marion Women’s Business Council created this scholarship fund in 2017 from member contributions to support future women in business. 

The Women’s Business Council Scholarship Fund annually awards a scholarship to a female student from a Marion County high school pursuing studies in business, finance, economics, marketing, management, advertising, accounting, human resources, or entrepreneurship.

Education - Higher Education

Hemophilia Health Equity Fund

Patient Advocate Foundation
Private
American Samoa, Guam +4 more
Up to US $12,500

Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Hemophilia Health Equity Fund

Help with healthcare costs for hemophilia (health equity fund)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code. 

Approved medications

Patient Advocate Foundation covers all the prescription medications for each diagnosis, including generic or bioequivalent drugs, that meet any of the following criteria: FDA-approved, listed in official compendia, and/or listed in published evidence-based or clinical guidelines. See approved medication list for this condition.

Patient Advocate Foundation verifies your diagnosis and treatment plan with your provider directly. We also automatically verify the income eligibility for every applicant. 

Health Care Access & Delivery Health Disparities & Social Determinants of Health

Cuyahoga County Grants for Nonprofits Highlights

Looking for Cuyahoga County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Cuyahoga County grants recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Cuyahoga County Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ Cuyahoga County grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

18 Cuyahoga County grants for nonprofits over $25K in average grant size

11 Cuyahoga County grants for nonprofits over $50K in average grant size

22 Cuyahoga County grants for nonprofits supporting general operating expenses

96 Cuyahoga County grants for nonprofits supporting programs / projects

600+ Grants on Instrumentl focused on Food Access & Hunger

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Cuyahoga County grants for Nonprofits?

Most grants are due in the fourth quarter.

Q1
24.1%
Q2
20.3%
Q3
25.1%
Q4
30.4%

Typical Funding Amounts

What's the typical grant amount funded for Cuyahoga County Grants for Nonprofits?

Grants are most commonly $10,000.

$750 $750 Min.
$10,000 $10 K Median
$55,525 $55.5 K Average
$800,000 $800 K Max.

Average Grant Size

What's the typical amount funded for Ohio?

Grants are most commonly $97,851.

$97,851

Total Number of Grants

What's the total number of grants in Cuyahoga County Grants for Nonprofits year over year?

In 2024, funders in Ohio awarded a total of 84,081 grants.

2022 78,879

2023 79,604

2024 84,081

Top Grant Focus Areas

Among all the Cuyahoga County Grants for Nonprofits given out in Ohio, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Cuyahoga County Grants for Nonprofits changing over time?

Funding has increased by -1.54%.

2022 $7,853,771,046

2023 $8,315,467,696
5.88%

2024 $8,187,079,289
-1.54%

Ohio Counties That Receive the Most Funding

How does grant funding vary by county?

Hamilton County, Cuyahoga County, and Franklin County receive the most funding.

County Total Grant Funding in 2024
Hamilton County $3,320,115,009
Cuyahoga County $2,821,239,308
Franklin County $2,035,647,424
Summit County $545,376,601
Scioto County $393,048,909

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