Best Grants for Preschools

The FY26 Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) aims to support impactful health services research that connects research, practice, and policy. It emphasizes building real-world evidence for interventions and clinical guidelines tailored to specific populations. Key features include requirements for clinical trials, preliminary data, and community-based participatory research approaches. The program also offers an Early-Career Investigator Partnering Option to foster collaboration between seasoned and emerging researchers.

The NCI Research Specialist Award (R50) supports clinician scientists involved in NCI-funded clinical trials. This funding opportunity encourages the development of stable research careers by providing salary support and autonomy, allowing clinician scientists to contribute to national clinical trial development and implementation. They play a critical role in sustaining the NCI clinical trials network without serving as principal investigators. This award aims to ensure continuity in cancer research careers.

The NCI Research Specialist Award (R50) supports non-tenure track scientists in cancer research who provide essential contributions within laboratories and core facilities. This award aims to enhance research careers for skilled scientists who do not seek independent investigator funding. Eligible candidates must possess an advanced degree, have at least two years of contribution to NCI-funded research, and dedicate a significant portion of their time to this work. The R50 offers salary support and travel funds to recognize and stabilize these vital roles in cancer research.

The National Swine Resource and Research Center (NSRRC) is a pivotal resource that enhances biomedical research by providing genetically modified models. This centralized facility reduces variability and costs for researchers, allowing them to focus on scientific discovery. NSRRC offers breeding, cryopreservation, and genotyping services, ensuring consistent access to high-quality models. By consolidating these resources, it promotes reproducibility and supports the development of innovative methodologies in research, ultimately advancing our understanding of human health and disease.

The DoW Traumatic Brain Injury and Psychological Health Translational Research Award aims to transform scientific discoveries into clinical applications. This program encourages innovative research approaches and requires preliminary data. It prohibits basic research and clinical trials, emphasizing the need for relevant animal models or community-based participatory research for human subjects. Funding supports two research levels, refining ideas into tangible products or evaluating them for clinical trials, with options for early-career investigator partnerships.

Information for Russell Sage Foundation Grant Seekers

RSF makes external grants for social science research projects that address questions of interest under its research priorities. 

Research Priorities

RSF supports high-quality innovative research under four core research priorities:

• Behavioral Science and Decision Making in Context
• Future of Work
• Race, Ethnicity, and Immigration
• Social, Political, and Economic Inequality

In addition, it supports research under the following time-limited co-funded research priorities:

• Immigration and Immigrant Integration
• Implications of the 2023 Supreme Court Decision to Ban Race-Conscious Admissions at Colleges and Universities for Educational Attainment and Economic Mobility
• Causal Research on the Criminal Justice System

Overview of Core Research Grants

All research grant applications must be preceded by a letter of inquiry (LOI). RSF has 3 funding cycles per year and only considers proposals that are invited following review of an initial letter of inquiry. After peer review, about 15% of those who submit an LOI will receive an invitation to submit a full proposal. RSF rarely considers projects for which the investigators have not already fully-developed the research design, the sample framework, access to data, etc. Investigators are encouraged to submit an LOI after they have developed and pre-tested survey instruments, completed preliminary data analyses if the data are publically-available or conducted some preliminary interviews for qualitative studies.

Funding

There are two levels of funding for core grants, Trustee-approved grants and Presidential-Authority grants. The maximum grant amount for a Trustee grant is $200,000, including 15% indirect costs. Grants up to $75,000 are considered Presidential-Authority grants. RSF has 3 funding cycles per year and only considers proposals that are invited following review of an initial letter of inquiry. After peer review, about 15% of those who submit an LOI will receive an invitation to submit a full proposal. The final funding rate for core research grants is approximately 6-10% of submitted LOIs.

Implications of the 2023 Supreme Court Decision to Ban Race-Conscious Admissions at Colleges and Universities for Educational Attainment and Economic Mobility - Request for Proposals

The Russell Sage Foundation, in collaboration with the Hewlett, Spencer, and William T. Grant foundations, seeks to support innovative research on the effects of the Supreme Court decision on a diversity of outcomes—from who attends college and where and the extent to which alternatives to race-conscious policies contribute to educational attainment and economic mobility among different groups in the population. Our interests extend beyond the effects on applications, admissions, enrollment, and degree completion and include the downstream effects, including whether and how the decision alters the college-to-career pipeline that many employers rely on to diversify their workforce, and the factors associated with public opposition to and support for race-conscious policies. We are particularly interested in analyses that make use of newly available data or demonstrate novel uses of existing data. We also support original data collection and encourage methodological variety and inter-disciplinary collaboration. 

Read the full RFP for this time-limited co-funded research priority here.

Joyful Heart Foundation

Since 2004, Joyful Heart has been a leading national organization with a mission to transform society’s response to sexual assault, domestic violence and child abuse by building a world that prioritizes survivors’ healing.

Our Areas of Focus

We continue to carry out our mission through programming centered on survivors’ needs. We strive to fill gaps where those needs aren’t being met, without duplicating existing programs. In order to build a more compassionate, more informed culture rooted in the possibility and promise of healing, we focus on three key areas: Awareness and Community Building, Policy and Advocacy and Healing Programs.

• Healing Programs and Resources: Creating and fostering a culture of healing and nurturing for survivors and the professionals who support them.
• Policy and Advocacy: Advocating for policies and practices that forge a path to safety, justice and hope for survivors.

• Awareness and Community Building: Creating spaces and conversations that channel a drive for change into action and transformation.

Heal the Healers Grant 

Helping alleviate the effects of secondary trauma for the long-term wellbeing of professionals who support survivors

Building for a System of Care and Compassion

Heal the Healers Grantmaking Program provides critical support for professionals who help survivors heal and seek justice. People working on the frontlines of survivor-centered services are subject to the often overlooked effects of secondary trauma that can emerge as a result of continuous exposure to people who have recently experienced abuse and violence.

The Heal the Healers Grant Fund and Grantee Learning Cohorts provide resources to mitigate the effects of secondary trauma among the practitioners responsible for the earliest stages of survivors’ paths to justice and healing. Creating a safer, more compassionate world for the people who do this work helps lay a foundation for lasting change and a world where every survivor’s healing is prioritized.

The Heal the Healers Fund provides micro-grants of up to $5,000 to nonprofit, Tribal, or governmental organizations supporting survivors for training, small capital projects, or organizational activities.

Areas of Support

The Joyful Heart Foundation has established the following guidelines for its Heal the Healers Fund grants to support those working directly with survivors in the following areas.

• Training and/or program development on self-care practices such as training in trauma-informed yoga, breathwork, somatic therapy, etc.
• Small capital items and equipment that specifically allow staff and volunteers to address their self care needs such as daylight lamps for staff or new furniture for a break room.
• Staff activities to build and support connections between colleagues such as, trust building experiences, monthly pizza nights, or bagel Fridays.
• Or any combination of the above. 

In addition to the financial support, grantees will also be invited to join a peer learning community cohort that includes:

• Opportunities to amplify their fellowship/cohort experiences to inspire others in the field
• Virtual peer-to-peer networking opportunities
• Virtual training/presentations by leading healers, therapists and other professionals with expertise in cutting edge vicarious trauma, empowerment, leadership and therapeutic modalities

Target Foundation

At Target Foundation, we envision a world where all families and communities have the resources they need to determine and realize their own joy in life. It’s a reality that is out of reach for far too many families as they struggle for access to economic opportunity, financial stability and the kind of empowerment that lifts up their communities. We believe we have a responsibility to work to remove barriers and to help create that access, resulting in a world where all families can thrive.

Community Engagement Funds

Community Engagement Funds (CEF) is a community grant program that empowers Target stores and distribution center leaders to make meaningful, localized giving decisions that meet the needs of the communities where our team members and guests live, work, and thrive.

• Organizations cannot apply for the same program in both grant cycles.
• Organizations are encouraged to apply during the cycle that best aligns with their program timing.
• A maximum of 10 applications is allowed per organization at any time.

CEF will prioritize nonprofit programs and initiatives aligned to its focus areas:

• Thriving Families; Basic needs and youth development..
• Vibrant Neighborhoods: Community vitalization; Community and green spaces.
• Emerging Creative & Culture: Cultural partnerships and creative programming.
• Economic Opportunity: Workforce development.

Virginia Department of Criminal Justice Services 

The Virginia Department of Criminal Justice Services (DCJS) is charged with planning and carrying out programs and initiatives to improve the functioning and effectiveness of the criminal justice system as a whole (Code of Virginia § 9.1-102).

The mission of the Virginia Department of Criminal Justice Services is to provide leadership to improve the criminal justice system in Virginia’s communities through effective training, partnerships, research, regulation, and support.

Office of First Responder Wellness Grant Program

The Virginia Department of Criminal Justice Services (DCJS) Office of First Responder Wellness is offering funding to support first responder wellness for current and retired first responders. The First Responder Wellness Grant Program is designed to support the mental, emotional, and physical well-being of first responders in the Commonwealth of Virginia. This funding opportunity aims to provide resources to agencies and non-profit organizations focused on promoting the overall health and wellness of individuals who serve on the front lines of public safety, including law enforcement, fire, emergency medical services, emergency communication officers, and corrections officers. 

These grant funds are to be used to support our first responders through programs addressing, but not limited to, emotional, physical, and overall personal wellness:

• Fund first responder wellness training for agency employees
• Fund registration fees, lodging, and per diem for agency employees to attend conferences related to first responder wellness
• Fund support costs for a therapy/support dog or costs for a dog already owned by an agency to attend training.
• Fund the purchase of therapeutic wellness equipment
• Provide funding for non-profit organizations to provide wellness training, resources, or direct services to first responders in the Commonwealth of Virginia

Hawai‘i State Foundation on Culture and the Arts

The mission of the Hawai‘i State Foundation on Culture and the Arts (SFCA) is to promote, perpetuate, and preserve culture and the arts in Hawai‘i. SFCA funding is provided by the State of Hawai‘i and the National Endowment for the Arts.

America250 Grant for Hawaiʻi Veterans

In celebration of the United States of America’s bicentennial, America250, the National Endowment for the Arts (NEA) allocated funding to state arts agencies nationwide to support arts projects celebrating the nation’s artistic heritage and creativity.

The project must celebrate America 250 through arts-based projects or programs directly focused on Hawaiʻi veterans. All project activities must be implemented in the State of Hawaiʻi. Proposals can include activities that honor veterans or improve the health and well-being of military and veteran communities. Examples of possible projects are arts and healing programs, visual arts, StoryCorps, spoken word, film, exhibition, performance, historical/heritage interpretations, and living history projects.

Hawai‘i State Foundation on Culture and the Arts

The mission of the Hawai‘i State Foundation on Culture and the Arts (SFCA) is to promote, perpetuate, and preserve culture and the arts in Hawai‘i. SFCA funding is provided by the State of Hawai‘i and the National Endowment for the Arts.

Community Arts Grant Program

The Community Arts Grants program (previously called Biennium Grants) supports eligible nonprofit 501(c)3 arts and culture organizations throughout the state. The grant awards funding to organizations supporting programs and projects that advance the arts, culture, and the humanities in the lives of the people of Hawaiʻi.

The legal provisions of the Community Arts Grants are in Sections 9-11 through 9-18 of the Hawaiʻi Revised Statutes. Each fiscal biennium grant budget is contingent on the State fiscal biennium and appropriations from the Hawaiʻi State Legislature and the National Endowment for the Arts. Grants awarded are subject to available funding for the fiscal year.

Grant Categories

Applicants may submit an application for a project to one of the following categories that align with the SFCA Strategic Priorities 2019-2023. Applicants can apply for one or both fiscal years, and the category and project can be the same or different for each year.

• Heritage/Preservation: Heritage and Preservation (Culture) projects are well grounded in the history of Hawaii and the living cultures in Hawaii. Amplify Hawaiian cultural arts, history, and heritage and support communities to advance cultural knowledge, build cultural capacity, and preserve cultural legacies.

• Community Arts, Community Development, Arts and Healing: Community Arts, Community Development, Arts & Healing (Engagement). Art-based community development projects that increase the creative capacity of rural communities and enhance opportunities to experience culture and the arts statewide and within rural communities and underserved populations.

• Arts Education: Arts Education (Education) provides educational opportunities in any arts discipline for arts in the school environment, out-of-school learning, Early Childhood Development, adult life-long learning, and professional development.

• Presenting & Performing Arts: Literacy Arts, Visual Arts, Media Arts, Performing Arts (The Arts). Projects support programs or activities of organizations that present artists in performances, exhibitions, in-residency settings, online format, and televised broadcasts. 

A Community Arts Grant can be requested in the amount of $5,000, $10,000, or $15,000. A 1:1 match is required. This is a reimbursement grant program.

Hawai‘i State Foundation on Culture and the Arts

The mission of the Hawai‘i State Foundation on Culture and the Arts (SFCA) is to promote, perpetuate, and preserve culture and the arts in Hawai‘i. SFCA funding is provided by the State of Hawai‘i and the National Endowment for the Arts.

Outreach Initiative Program

The State Foundation on Culture and the Arts (SFCA) provides public funds through the Outreach Initiative Program to support statewide touring and outreach activities that increase opportunities for individuals to experience different forms of artistic and cultural expression and engagement. The program supports the SFCA Strategic Priority Hoʻākoakoa (convene, to call together) to build community capacity for creativity, communication, and learning.

Program Scope

Administer a statewide touring program providing arts and culture outreach activities to under-served communities including, but not limited to, rural, socio-economic disadvantaged, geographically disadvantaged, programs for disadvantaged youth, programs for Native or immigrant populations, and activities involving individuals with varying abilities. The touring and outreach activities must be accessible. Activities must occur in person at public spaces, senior centers, public libraries, public housing communities, or a hybrid of online/streaming. The Outreach Initiative Program must provide activities to at least three (3) islands, including outreach to rural and/or under-served communities.

The Grant for Grassroots Exchange: Japan Festivals and Events supports cultural projects promoting understanding of Japan through local festivals and events. Aimed at community-driven initiatives, the grant encourages cross-cultural exchange and global perspectives while providing up to $7,000 in funding. Priority is given to projects reaching underserved communities in the Midwest, Mountain, and South regions, involving new participants in K-12 education, and demonstrating potential for replication in other areas.

The Grant for Grassroots Exchange: U.S.-Japan Community Networking supports initiatives that foster connections between grassroots communities in the U.S. and Japan. With funding up to $10,000, projects should enhance mutual understanding through events like workshops and conferences. Eligibility is limited to U.S. organizations with 501(c)(3) status, and priority is given to collaborations with underrepresented groups. This grant aims to strengthen community ties and promote cultural exchange on a local level.

About the DNR

Preserving and enhancing the natural resources of Wisconsin

In keeping with our mission, the DNR is dedicated to working with Wisconsinites while preserving and enhancing the natural resources of Wisconsin. In partnership with individuals and organizations, DNR staff manage fish, wildlife, forests, parks, air and water resources while promoting a healthy, sustainable environment and a full range of outdoor opportunities.

Aquatic Invasive Species Control – Large or Small-Scale Population Management

(See page 31 of attatched PDF)

When an established population of aquatic invasive species is having adverse effects on a waterbody or wetland, funding is available for control activities. Managing aquatic invasive species can be challenging, but adaptive and integrated pest management can help. Participation in the large- or small-scale control program requires an approved recommendation in an aquatic plant or aquatic invasive species management plan. Eligible projects will implement one or more of the resulting recommendations. Public access required, unless controlling a prohibited species.

DNR cost share: Grants may cover up to 75% of total project costs.

The AIS Population Management Grant includes Small-Scale Population Management Projects and Large-Scale Population Management Projects.

Small-Scale Population Management Projects

Small-Scale Population Management projects will maintain a low abundance of one or more aquatic invasive species populations or further reduce their size. Projects should implement management activities with the goal of continued suppression of the target species where the actions are unlikely to affect the entire lake, stream reach or wetland. Projects should be designed to result in long-term, multi-season suppression of one or more established populations of the target species.

About the DNR

Preserving and enhancing the natural resources of Wisconsin

In keeping with our mission, the DNR is dedicated to working with Wisconsinites while preserving and enhancing the natural resources of Wisconsin. In partnership with individuals and organizations, DNR staff manage fish, wildlife, forests, parks, air and water resources while promoting a healthy, sustainable environment and a full range of outdoor opportunities.

Aquatic Invasive Species Control – Large or Small-Scale Population Management

(See page 31 of attatched PDF)

When an established population of aquatic invasive species is having adverse effects on a waterbody or wetland, funding is available for control activities. Managing aquatic invasive species can be challenging, but adaptive and integrated pest management can help. Participation in the large- or small-scale control program requires an approved recommendation in an aquatic plant or aquatic invasive species management plan. Eligible projects will implement one or more of the resulting recommendations. Public access required, unless controlling a prohibited species.

DNR cost share: Grants may cover up to 75% of total project costs.

The AIS Population Management Grant includes Small-Scale Population Management Projects and Large-Scale Population Management Projects.

Large-Scale Population Management Projects

Large-Scale Population Management projects will result in long-term, multi-season suppression of one or more established populations of aquatic invasive species. Projects are large in scale, affecting a substantial portion of a lake, stream reach, or wetland.

Projects that address multiple populations across a region should employ a strategic approach to managing multiple populations, prioritizing control actions in a way that ensures wise spending of grant funds. For example, a regional wetland control project might focus on populations that threaten high-functioning natural wetlands or focus on small, more easily controlled populations. For Phragmites-focused projects seeking AIS planning and control grant funds, please see the Phragmites Statewide Management Strategy for more specific guidance.

About the DNR

Preserving and enhancing the natural resources of Wisconsin

In keeping with our mission, the DNR is dedicated to working with Wisconsinites while preserving and enhancing the natural resources of Wisconsin. In partnership with individuals and organizations, DNR staff manage fish, wildlife, forests, parks, air and water resources while promoting a healthy, sustainable environment and a full range of outdoor opportunities.

ATV/UTV Trail Aids Program

A financial assistance program administered by the Wisconsin Department of Natural Resources

The all-terrain vehicle and utility terrain vehicle trail aids grant program was created with section 23.33, Wis. Stats. This law authorizes the Department to administer a program of financial assistance to local units of government and federal agencies for the acquiring, developing, rehabilitating, insuring and maintaining of off-road all-terrain and utility terrain vehicle trails, intensive use areas, and more. 

Counties, towns, cities, villages and tribes can apply for funds to acquire, insure, develop and maintain ATV/UTV trails, areas and routes.

Ranking Priorities

Trail funds are distributed according to the following ranked purposes (NR 64.14 [exit DNR]):

• maintenance of existing, approved trails, areas, and routes;
• liability insurance acquisition;
• easement acquisition;
• major rehabilitation of bridge structures or trails; and
• Land acquisition and development of new ATV trails and areas.

Eligible items and funding levels include:

• all-terrain/utility-terrain vehicle trails available for spring, summer, and fall reimbursable up to 100 percent of eligible maintenance costs (max: $1,000 per mile);
• all-terrain vehicle trails available for winter riding reimbursable up to 100 percent of eligible maintenance costs (max: $100 to $300 per mile depending on other uses);
• development of ATV trails and areas reimbursable up to 100 percent of eligible costs;
• major rehabilitation of bridge structures or trails reimbursable up to 100 percent of eligible costs; and
• maintenance of ATV intensive use areas reimbursable up to 50 percent of eligible costs.

About the DNR

Preserving and enhancing the natural resources of Wisconsin

In keeping with our mission, the DNR is dedicated to working with Wisconsinites while preserving and enhancing the natural resources of Wisconsin. In partnership with individuals and organizations, DNR staff manage fish, wildlife, forests, parks, air and water resources while promoting a healthy, sustainable environment and a full range of outdoor opportunities.

Boat Enforcement Patrol Grants

This grant is issued to Wisconsin counties or municipalities that participate in boating enforcement efforts. Eligible agencies may receive law enforcement aids for up to 75% of their net costs.

Every 2 years, a patrol representative must attend a water safety patrol biennial workshop, date to be scheduled and notice sent out by the Bureau of Law Enforcement. Attendance is limited to 2 participants per patrol. At least one attendee must be an active officer of the patrol.

About the DNR

Preserving and enhancing the natural resources of Wisconsin

In keeping with our mission, the DNR is dedicated to working with Wisconsinites while preserving and enhancing the natural resources of Wisconsin. In partnership with individuals and organizations, DNR staff manage fish, wildlife, forests, parks, air and water resources while promoting a healthy, sustainable environment and a full range of outdoor opportunities.

Boating Infrastructure Grant (BIG) Program

The purpose of BIG is to construct, renovate and maintain boating infrastructure facilities for transient recreational vessels at least 26 feet long.

Project Cost

• Construction, renovation and maintenance of boating infrastructure tie-up facilities, solely for transient recreational vessels 26 feet or more in length. Does not include: Commercial vessels, cruise ships, dive boats, ferries and vessels that operate permanently from the proposed project location.
• Produce information and education materials specific to BIG or BIG funded projects (i.e. charts, cruising guides, and brochures).

Special Conditions or Requirements

• Facilities constructed, operated or maintained with grant funds must offer reasonable access for all transient recreational vessels for the full period of their useful life.
• Facilities must be open to the public during reasonable time periods.
• Entities may charge fees. Fees must be comparable to the prevailing rate in the area.
• New construction and renovations must be designed to last throughout its useful life.
• BIG grants require a minimum of 25% matching funds, federal share not to exceed 75% total costs.

The Boating Infrastructure Grant (BIG) Program has two Tiers: Tier 1 - State; and Tier 2 - National

Tier 1 - State

Provides up to $300,000 per year to the state of Wisconsin. Projects are competitively ranked within the state.

El Pomar Foundation

El Pomar Foundation was established in 1937 by Spencer and Julie Penrose, creating an enduring legacy to carry out their philanthropic wishes.

Our Mission: Since 1937, we have continued the mission set by Spencer and Julie Penrose to enhance, encourage, and promote the current and future well-being of the people of Colorado.

El Pomar's Grant Making

• El Pomar provides grants for general operating support, programs, and capital needs.
• The Trustees are interested in increasing support in Southern and rural Colorado. While they make grants in metro Denver, they are much more competitive in that region.
• Due to the tremendous need throughout the state of Colorado, requests, if funded, are often funded at lesser levels than requested. Generally speaking, the Trustees prefer to go broad rather than deep and therefore tend to make a lot of smaller grants rather than a few larger ones.
• For programs and capital needs, we recommend having about half the needed funds secured before submitting an application.

Bill and Kathy Hybl Fund

Mission: The Hybl Fund supports Olympic, Paralympic, and youth sports.

History: Bill Hybl, a lifetime public servant, has long been dedicated to amateur sport. Currently chairman of the United States Olympic Endowment, he believes the ideals of excellence, fair play, and hard work through sport are important for athletes as well as children.

If funded, applicants must wait two years (24 months) to be considered again. If declined, applicants must wait one year (12 months) to be considered again.

About KIP:D+ Cultural Heritage

Kresge Innovative Projects: Detroit Plus (KIP:D+) funds projects in Detroit, Hamtramck and Highland Park neighborhoods that support the vision and creativity of residents. We support inclusive, collaborative processes that authentically engage community members in planning, design and implementation.

Through project funding, capacity building, and support for transformative initiatives, KIP:D+ enables grantees to foster resilience, collaboration, and meaningful change.

This round of KIP:D+ focuses on Cultural Heritage. We’re funding arts, culture, and community projects that help neighborhoods remember their history, share stories and traditions, and carry forward community legacy.

The F26AS00084 Aquatic Invasive Species Grants to Great Lakes Tribes, funded by the U.S. Fish and Wildlife Service, aim to support the development and implementation of Tribal Aquatic Invasive Species Management Plans. Eligible Great Lakes tribes can apply for competitive grants to address invasive species issues within the Great Lakes Basin, including outreach and prevention efforts. This initiative focuses on early detection and control, significantly contributing to the health of the Great Lakes ecosystem.

The DoW Toxic Exposures Translational Research Award aims to foster translational research that bridges military-related toxic exposure studies and clinical applications. This program encourages innovative collaborations by allowing for a Partnering Principal Investigator Option, enhancing interdisciplinary partnerships. By integrating basic science with clinical insights, the initiative seeks to expedite the development of impactful health care products and interventions to address toxic exposures faced by military personnel.

The FY26 Toxic Exposures Research Program (TERP) Clinical Trial Award supports clinical trials aimed at addressing health issues from military-related toxic exposures. This initiative encourages collaboration through a Partnering Principal Investigator Option, enhancing interdisciplinary research efforts. Projects range from early-phase trials to large-scale studies, focusing on innovative treatments and management strategies for affected populations. The goal is to expedite the translation of research findings into effective clinical applications.

The DoW Toxic Exposures Investigator Initiated Research Award aims to fund critical studies addressing diseases linked to military-related toxic exposures. This award supports a wide range of research phases, from basic laboratory investigations to translational research involving both animal models and human subjects. Projects may also explore New Approach Methodologies, enhancing our understanding and treatment options for affected individuals. By facilitating innovative research, this initiative seeks to improve patient care and outcomes.

The NIH Blueprint Initiative aims to enhance neuroscience research by funding the development and application of germline and somatic gene-editing techniques. This initiative builds on existing marmoset gene-editing frameworks and integrates New Approach Methodologies (NAMs) to improve understanding of human brain function and disease. High-priority areas include complex conditions like autism and schizophrenia. The initiative emphasizes the use of appropriate models to address critical questions in neuroanatomy, cognition, and behavior related to human brain health.

The Intervention Research to Improve Native American Health (IRINAH), led by the National Institute on Drug Abuse, focuses on enhancing health outcomes in Native populations. It supports research to identify causes of health issues, develop and test effective interventions, and implement strategies that promote sustainability. Emphasizing community strengths, the initiative aims to rigorously evaluate solutions to reduce health disparities, ensuring interventions can be adapted and shared across diverse communities.