Best Lenawee County Grants for Nonprofits in Michigan

Myasthenia Gravis Rare Disease Network (MGNet)

The Myasthenia Gravis Rare Disease Network (MGNet) is a consortium of academic medical centers partnering with the Myasthenia Gravis Foundation of America and Conquer MG as well as collaborators in other research groups and industry. We are working together to enhance therapeutic development for this rare disease.

Diseases Studied

Myasthenia Gravis (MG) and its subtypes:

• Early-onset acetylcholine receptor (AChR) antibody (Ab) positive MG, which primarily affects women
• Late-onset AChR Ab positive MG with a disease bias towards men
• Paraneoplastic thymoma-associated MG
• Muscle specific kinase (MuSK) Ab positive
• AChR/MuSK antibody negative MG

Goals, Mission, & Vision

The goal of MGNet is to advance therapeutic development. To do so we have four specific aims:

• Improve the tools scientists and doctors have for performing clinical trials through rigorous monitoring of patients over time and evaluate better measures of how patients are doing.
• Identify objective measures (biomarkers) to show how the disease is responding to treatment and better predict treatment response or side effects, to improve the design of clinical trials and care of patients in clinical practice.
• Enhance the education of young investigators focusing their careers on rare diseases and specifically MG.
• Improve the awareness of scientists, physicians, and the public regarding the unique needs of patients with MG through training of clinician scientists and engagement of the patient and scientific communities in clinical research and therapeutic development.

Pilot and Feasibility Grants

Objectives

MGNet, a NIH-funded Rare Diseases Clinical Research Consortium (RDCRC) in partnership with the Myasthenia Gravis Foundation of America and Conquer MG, is seeking proposals for highly innovative investigations in early stages of development.

The priorities of the Pilot Grant Program are:

• Identification treatment responsive biomarkers
• Assess clinical measures and improve that enhance clinical trial readiness
• Evaluation of therapeutic interventions for one or more of the five distinct sub-types of MG

Pilot studies must be designed to access the resources of MGNet and focused on clinical and translational research, including fulfilling the definition of clinical and translational research and exclusion of animal studies.

Funding

The MGNet expects to fund up to two grants, each at a level of $75,000 (IDCs will be limited to 10% and included in the $75,000). Projects will be funded for 12 months. Selection among the applications received will be based on the recommendations of a review committee. A grant may be renewed for an additional one year with approval of interim report by the same review process and availability of funds. Demonstration of fulfillment of initial aims and justification for additional funding will be required. The request will be required a minimum of three months prior to the initial funding period completion.

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The TESOL Teacher of the Year Award, presented by National Geographic Learning, honors exceptional English language teachers who have demonstrated outstanding dedication in the classroom for at least three consecutive years. The winner receives $1,000, a one-year TESOL membership, and free registration for the TESOL International Convention, including travel accommodations. This recognition not only highlights the importance of teaching excellence but also fosters a community of learning and collaboration among educators around the world.

The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs to enhance equitable learning environments. Grants of up to $500,000 will support projects addressing systemic barriers, promoting effective practices, and ensuring seamless transitions from MSIs to advanced degrees in various STEM fields. The initiative seeks to create lasting impacts on student access and success in graduate education.

The Prof. Chan Two-Year College Award for the Engaged Teaching of Biology recognizes outstanding contributions by Two-Year College faculty who develop and implement innovative, inclusive pedagogical approaches. Sponsored by Sarah McBride and John Melville, this award emphasizes the impact of teaching on a broader student population and includes a $500 travel grant for the NABT Professional Development Conference, fostering professional development and collaboration among biology educators.

The Two-Year College Biology Teaching Award, sponsored by the National Association of Biology Teachers (NABT), recognizes outstanding biology educators in two-year colleges who implement innovative teaching techniques. This award highlights the importance of culturally responsive pedagogies that foster equity and inclusion in various learning environments. Recipients receive a $500 travel honorarium, a recognition plaque, and one year of complimentary NABT membership, supporting their professional development and commitment to enhancing biology education.

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The Everett Kneece Scholarship, offered by the Foundation for Rural Service, provides a $7,000 award annually to a graduating high school senior who shows commitment to returning to a rural community. To be eligible, applicants must be U.S. citizens sponsored by an NTCA member and express interest in rural community service. This scholarship honors Everett Kneece's legacy of philanthropy and dedication to enhancing rural life through education.