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Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease
The Challenge
Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).
The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.
This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.
Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows
Catalyzing Innovation through Partnerships
At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.
About this Challenge
This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).
Award Structure and Funding Level
To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:
For technically ambitious or higher-risk, earlier-stage concepts focused on feasibility testing, assay or workflow prototyping, and initial cost-reduction validation. Intended approaches that require focused development to demonstrate viability.
Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows
Catalyzing Innovation through Partnerships
At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.
About this Challenge
This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).
Award Structure and Funding Level
To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:
For concepts with preliminary feasibility evidence that are ready to advance from prototype toward an integrated workflow—optimizing performance, broadening assay or pathogen coverage, and generating more robust cost-reduction and performance data.
Innovations in Low-Cost and Simplified Pathogen Sequencing Workflows
Catalyzing Innovation through Partnerships
At its core, Grand Challenges catalyzes bold innovation through partnership - bringing together funders, researchers, implementers, and public health leaders to solve complex global challenges. This multi-partner initiative reflects the Grand Challenges ethos, leveraging complementary expertise and investments to accelerate accessible genomic sequencing solutions for low- and middle-income Countries.
About this Challenge
This Grand Challenge is co-funded by the Gates Foundation, and the Temasek Foundation, and will be managed by the United Nations Foundation. This Grand Challenge is implemented in collaboration with a network of global and regional partners, including International Pathogen Surveillance Network (IPSN), hosted by the WHO Hub for Pandemic and Epidemic Intelligence, the Africa Pathogen Genomics Initiative (Africa PGI), and the Asia Pathogen Genomics Initiative (Asia PGI) as regional technical and public-health partners. This RFP aims to accelerate the development of affordable, scalable, and operationally simple sequencing solutions, enabling routine use of genomics for public health in low- and middle-income countries (LMICs).
Award Structure and Funding Level
To accommodate different stages of innovation maturity, this RFP supports a tiered award structure, with funding levels and expectations aligned to the readiness and scope of the proposed work. Indicative award categories are:
For more mature concepts aimed at workflow refinement, performance optimization, and generation of proof-of-concept and validation data in relevant public-health use cases in LMICs.
About The American Chestnut Foundation:
Our mission is to return the iconic American chestnut to its native range.
Our vision is a robust eastern forest returned to its splendor.
Small Grants Program
Are you looking for funding to support your American chestnut research? External small grants offer recipients a variety of benefits such as professional development and an expanded network. Grant activities contribute to the continuous renewal and development of faculty and staff, to the education and motivation of students, and achievement of our mutual interest — restoration of the American chestnut. This is a small grants program. TACF does not ordinarily fund projects in excess of $10,000.
Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre
Our Mission and Goals
The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).
ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:
Grants for Educators & Theatre Programs
A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.
For EdTA Members
Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.
Production Grants
Show-specific financial assistance for educational theatre programs
The Wilder Estate: The Long Christmas Dinner Festival Grant
In 1931, Thornton Wilder wrote The Long Christmas Dinner, a moving, funny, and ingeniously theatrical one-act play created specifically for student theater groups. In just 40 minutes, a single holiday meal becomes a 90-year journey through four generations of a family, exploring time, tradition, family, and the stories we tell about our lives.
In 2026, the Wilder Estate is launching The Long Christmas Dinner Festival, a national holiday celebration bringing schools, cultural organizations, and audiences together around this remarkable play.
Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre
Our Mission and Goals
The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).
ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:
Grants for Educators & Theatre Programs
A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.
For EdTA Members
Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.
Production Grants
Show-specific financial assistance for educational theatre programs
Music Theatre International: Heart of Rock and Roll "The Power of Love" Grant
Heart of Rock and Roll features a book by Jonathan Abrams and music and lyrics by Huey Lewis and his pop-rock band, Huey Lewis and the News, with new orchestrations of their music by Brian Usifer.
Selected schools will host intergenerational community events or outreach programs of their own design — because just as Huey Lewis’s music has always brought people together, school theatre has the power to do the same.
Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre
Our Mission and Goals
The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).
ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:
Grants for Educators & Theatre Programs
A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.
For EdTA Members
Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.
Production Grants
Show-specific financial assistance for educational theatre programs
Disney on Broadway: School of Excellence Grant
In collaboration with the Educational Theatre Foundation and Music Theatre International, Disney Theatrical Group will award complimentary licenses of select Disney musicals to middle and high schools throughout the United States to be performed each school year.
This nationwide program celebrates schools that display both outstanding artistic achievement and student-led engagement in theatrical disciplines such as stagecraft, theatrical design, choreography, direction, or performance. Together, these schools will honor the timeless magic of Disney musicals on stage and represent the future of theatrical storytelling for the next generation.
Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre
Our Mission and Goals
The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).
ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:
Grants for Educators & Theatre Programs
A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.
For EdTA Members
Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.
Production Grants
Show-specific financial assistance for educational theatre programs
Austen's Pride: A New Musical of Pride and Prejudice Grant
The Authors of Austen’s Pride: A New Musical of Pride & Prejudice are thrilled to announce a collaboration with ETF to grant five (5) high schools free performance rights and materials to produce this beautiful new musical during the 2026-27 school year. Access a free digital perusal of the script.
Building a global community of creative problem solvers, effective collaborators, and empathetic individuals through theatre
Our Mission and Goals
The Educational Theatre Foundation (ETF) is the philanthropic arm of the Educational Theatre Association (EdTA).
ETF advances the field of educational theatre by broadening representation and increasing access for all. ETF’s programs aim to support students, educators and the field at large by realizing three strategic goals:
Grants for Educators & Theatre Programs
A core piece of the Educational Theatre Foundation’s work is supporting theatre educators and theatre programs directly. We do this through a series of production and educator grants available to both members of EdTA as well as non-members.
For EdTA Members
Production Grants are offered in collaboration with the rights holders for specific plays and musicals or for initiative-based productions that build community.
Production Grants
Show-specific financial assistance for educational theatre programs
Fiddler on the Roof Grant
The Fiddler on the Roof Grant covers performance royalties and support resources for middle or high school Thespian troupes to perform Fiddler on the Roof or Fiddler on the Roof JR. through Music Theatre International. Funders Helene and Edward Cole created the grant to help educate students and communities about Jewish heritage and culture.
Howard Hughes Medical Institute
More than 70 years ago, the Howard Hughes Medical Institute (HHMI) was founded with a mission to advance basic biomedical research and science education. Today, we invest in exceptional scientists at all career stages, catalyzing breakthroughs, new technologies, and the next generation of transformative clinical therapies. Our pathbreaking science takes place at more than 60 host institutions across the US, and at our Janelia Research Campus.
Cech Fellows Program
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
The Summer Undergraduate Research Program (the Cech Fellows Program) gives undergraduate students in the life sciences the opportunity to conduct hands-on research alongside leading scientists at HHMI laboratories across the US, from universities and research institutions to HHMI’s research campus outside of Washington, DC. Students are matched with HHMI scientists conducting fundamental research that advances our understanding of biology and health.
This immersive program gives students the chance to contribute to real scientific discovery, gain professional mentorship, and explore potential careers in biological and biomedical research.
Gain Hands-On Experience in Research & Lab Work
Through the summer, students will:
What the Program Offers
Beyond meaningful lab work, the program provides:
Puget Sound Energy (PSE)’s Solar Grants are funding to increase equitable access to the benefits of solar. In 2026, PSE is offering $1,000,000 in competitive funding awards to community-based organizations, government agencies and Tribal entities in PSE’s electric service area to install solar at their property.What makes a solar project eligible?
About Samba RecoverySamba Recovery is dedicated to empowering individuals recovering from alcoholism and drug addiction by restoring confidence and fostering resilience. Through a foundation of compassion, support, and holistic care, we guide individuals toward renewed health and wellness, meaningful relationships, and the discovery of their inner strengths—assisting them to achieve their fullest potential.Hope for Addiction ScholarshipSamba Recovery’s Hope for Addiction Scholarship is an annual $1,000 award dedicated to encouraging more young people to join the fight against addiction by pursuing degrees that directly support individuals and families affected by substance use disorders.
We welcome applications from all eligible students, with special encouragement for those who are in recovery themselves or who have been impacted by addiction within their families.Application requirements:
We are Revolutionaries
Who We Are
We are Revolutionaries -passionate in our singular pursuit of discovering, developing and delivering innovative targeted therapies for patients living with RAS-addicted cancer. At Revolution Medicines, we believe in challenging the status quo to find new therapeutic approaches to some of the toughest cancers. With our first wave of investigational RAS(ON) inhibitors, we are pioneering a new way of targeting the RAS cancer drivers of disease, and we have the potential to change the treatment paradigm in these cancers where there is a significant unmet medical need.
Our mission is to revolutionize treatment for patients with RAS-addicted cancers through the discovery, development and delivery of innovative, targeted medicines.
Research, Grants & Support
At Revolution Medicines, we understand the importance of extending our support of scientific advancement beyond the research we conduct and the medicines we provide.
We support activities that make meaningful information and resources available to the broader medical and scientific communities to help advance science, increase understanding of certain diseases, and enhance patient care.
Charitable Donations
Funding for programs that deliver disease awareness, treatment education, or other healthcare information intended to improve patient understanding and empowerment.
Joseph G Markoly Foundation Inc
When Joseph Markoly originally established the foundation more than thirty years ago, its focus was on Alzheimer’s and heart disease support, funded through a number of the larger national disease-related organizations. Over time the focus has shifted to helping small to mid-size organizations in our local communities which support children and seniors in a variety of effective ways.
Markoly Foundation was established in honor of Joseph G. Markoly, an entrepreneur and philanthropist who wanted to make a positive impact in people’s lives. Joseph’s family was affected directly by both Alzheimer’s and heart disease having lost a family member to each condition. For that reason, the foundation dedicates a majority of their resources to providing grants to organizations that focus on the treatment of each of these diseases. In addition, Markoly Foundation supports a variety of programs dedicated to helping children and seniors by providing services, supplies, programs and research in areas impacting these demographics.
Joseph G. Markoly Foundation Grant Support for Elder Organizations
The Markoly Foundation takes pride in supporting local organizations that provide services for elders in our community. Seniors face a number of challenges that come with aging, especially when they don’t have loved ones who are able to assist them with their needs. We provide grants for a variety of senior-related programs from Caregiver Education and Support to Emergency Meal Delivery and Transportation Services.
We are dedicated to providing funding for local nonprofit programs that improve the quality of life for all, but particularly for the children and elders in our community.
Joseph G Markoly Foundation Inc
When Joseph Markoly originally established the foundation more than thirty years ago, its focus was on Alzheimer’s and heart disease support, funded through a number of the larger national disease-related organizations. Over time the focus has shifted to helping small to mid-size organizations in our local communities which support children and seniors in a variety of effective ways.
Markoly Foundation was established in honor of Joseph G. Markoly, an entrepreneur and philanthropist who wanted to make a positive impact in people’s lives. Joseph’s family was affected directly by both Alzheimer’s and heart disease having lost a family member to each condition. For that reason, the foundation dedicates a majority of their resources to providing grants to organizations that focus on the treatment of each of these diseases. In addition, Markoly Foundation supports a variety of programs dedicated to helping children and seniors by providing services, supplies, programs and research in areas impacting these demographics.
Joseph G. Markoly Foundation Grant Support for Children’s Organizations
Children are the future of this world and the Markoly Foundation is proud to fund local programs dedicated to improving the lives of children and their families. From providing vision services for school kids to classes on parenting, we are proud to do our part to help fund critical community programs for families.
We are dedicated to providing funding for local nonprofit programs that improve the quality of life for all, but particularly for the children and elders in our community.
Looking for Martinsville city grants for nonprofits?
Read more about each grant below or start your 14-day free trial to see all Martinsville city grants recommended for your specific programs.
What's the typical amount funded for Virginia?
Grants are most commonly $113,117.
What's the total number of grants in Martinsville city Grants for Nonprofits year over year?
In 2024, funders in Virginia awarded a total of 69,694 grants.
Among all the Martinsville city Grants for Nonprofits given out in Virginia, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.
1. Education
2. Philanthropy, Voluntarism & Grantmaking Foundations
3. Human Services
How is funding for Martinsville city Grants for Nonprofits changing over time?
Funding has increased by 9.79%.
How does grant funding vary by county?
Fairfax County, Arlington County, and Alexandria City receive the most funding.
| County | Total Grant Funding in 2024 |
|---|---|
| Fairfax County | $2,293,731,782 |
| Arlington County | $2,240,636,439 |
| Alexandria City | $719,704,106 |
| Richmond City | $452,557,663 |
| Loudoun County | $376,230,846 |