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Best Operating Grants for Nonprofits in Massachusetts

Find the perfect Operating grants for nonprofits in Massachusetts on Instrumentl. 10,000+ Operating grants for nonprofits in Massachusetts in the United States.

10,000+

Available grants

$2.65B

Total funding

$5K

Median grant

10,000+ grants
$2.65B total
$5K median

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9,710 Results based on applied filters

Healthy American Forests Initiative

National Fish and Wildlife Foundation (NFWF)
Private
Puerto Rico, United States +1 more
US $250,000 - US $2,000,000
The Healthy American Forests Initiative, led by the National Fish and Wildlife Foundation (NFWF), aims to enhance forest health and resilience through targeted funding. This initiative anticipates awarding 10-15 grants ranging from $250,000 to $2 million, supporting projects up to 2 years in duration. A 20% non-federal match is required, and interested applicants are encouraged to collaborate with NFWF and Native Americans in Philanthropy for potential match funding.
Environmental Conservation Water Resource Management

Liberty Mutual Foundation- Discretionary Grants

Liberty Mutual Foundation
Corporate
King County, Washington, Kitsap County, Washington +5 more
Unspecified amount
The Liberty Mutual Foundation offers discretionary grants to 501(c)(3) organizations, focusing on those that empower low-income youth and young adults. The foundation prioritizes initiatives that align with its strategic framework and serves communities in Greater Boston and select areas in Washington State. Funding is not available for individuals, religious organizations, or those who have received support in the last 12 months, ensuring resources are directed towards impactful community-driven projects.
Youth Services Community / Public Safety Poverty Alleviation & Services +9 more

Lundbeck US Charitable Fund: Sponsorships

Lundbeck Us Charitable Fund
Private
United States
Unspecified amount
The Lundbeck US Charitable Fund focuses on enhancing brain health through sponsorships that support various initiatives. These sponsorships are available to both non-profit and for-profit organizations, provided they align with Lundbeck's mission. Funds are primarily allocated for educational or awareness events, with an emphasis on community outreach and collaboration to address gaps in care, especially for vulnerable populations. By fostering innovative strategies, the Fund aims to drive meaningful change in the field of brain health.
Military & Veterans Services Cognitive Science Neuroscience +4 more

Rapid Response Opioid And Pain Management ECHO Funding Opportunity

Association of State and Territorial Health Officials (ASTHO)
Association/Society
American Samoa, Guam +4 more
Up to US $140,000
The Rapid Response Opioid and Pain Management ECHO Funding Opportunity by the Association of State and Territorial Health Officials (ASTHO) aims to enhance clinician training in effective pain management strategies. This initiative focuses on non-opioid treatments, substance use screening, and risk reduction counseling, promoting compassionate care while addressing public health challenges and ensuring continuity for patients affected by prescription disruptions. The program seeks to improve overall health outcomes and reduce risks associated with opioid use.
Drug Use Disorder Chronic / Acute Pain

Lundbeck US Charitable Fund: Charitable Donations

Lundbeck Us Charitable Fund
Private
United States
Unspecified amount
The Lundbeck US Charitable Fund focuses on enhancing brain health through impactful donations. Established to support organizations dedicated to brain health, it addresses pressing needs by funding innovative strategies and community collaborations, particularly for at-risk populations. The Fund aims to transform lives and improve mental health care, with a commitment to responsible giving. With over 20 organizations supported in 2023, it drives meaningful change in communities affected by brain disorders.
Neurological Diseases & Disorders Mental Health & Psychiatric Diseases Cognitive Intervention & Therapy +4 more

Enterprise Mobility™ Philanthropic Giving

Enterprise Holdings Foundation
Corporate
Canada, France +5 more
Unspecified amount
The Enterprise Mobility™ Philanthropic Giving program focuses on enhancing community engagement through grants aimed at supporting health, education, arts, and disaster relief initiatives. Only Enterprise Mobility team members and their spouses or domestic partners who volunteer with a nonprofit can apply for funding. The program prioritizes sustainable projects that uplift local communities and address pressing social issues, fostering a culture of responsibility and giving back to society.
Disaster Relief / Humanitarian Aid Workforce Preparation & Job Readiness Economic Services & Development +4 more

Science Policy Fellowship

American Chemical Society
Association/Society
United States
Unspecified amount
The Science Policy Fellowship, offered by the American Chemical Society, provides a unique opportunity for trained scientists to engage in public policy. This program enhances understanding of the policy-making process, allowing Fellows to work alongside experienced Government Affairs staff. The Fellowship focuses on key areas such as federal research funding, education in STEM, and environmental policies. Candidates with a strong background in chemical sciences or engineering are encouraged to apply, regardless of holding a doctorate.
Environmental Chemistry & Toxicology Environmental Justice & Advocacy Environmental Policy

RFP: Using Real-World Data to Address Prevalence and Treatment of Cardiovascular, Kidney and Metabolic Disease in Cancer Patients and Survivors

American Heart Association
Association/Society
United States
US $150,000
The American Heart Association is seeking proposals to study the prevalence and treatment of cardiovascular, kidney, and metabolic diseases among cancer patients and survivors. Given the over 16.7 million cancer survivors in the U.S., this research aims to highlight critical health disparities, identify treatment modalities, and explore shared risk factors. Applications focusing on underrepresented populations and utilizing real-world data sources are especially encouraged, aiming to improve health outcomes in this vulnerable group.
Cancer / Oncology Cardiovascular Diseases & Systems Kidney Diseases +1 more

Mike & Sofia Segal Foundation Grant

Mike & Sofia Segal Foundation
Private
United States
Unspecified amount
The Mike & Sofia Segal Foundation Grant provides vital funding to nonprofit organizations focused on intellectual freedom, medical research for rare diseases, Jewish heritage preservation, elder care, and climate change initiatives. By supporting innovative projects that align with their mission, the foundation aims to uplift communities and foster meaningful societal contributions. Organizations must be 501c-3 compliant and demonstrate a clear plan for engagement with beneficiaries and measurable objectives to be eligible for funding.
Senior Services Rare Diseases Climate Change Resilience & Equity +2 more

Graduate Education Fund: Specialty Field Scholarships - AUKUS Scholarship

American Australian Association
Private
Australia, United States
Up to US $40,000
The AUKUS Scholarship, part of the Graduate Education Fund, supports American and Australian graduate students in security, technology, and diplomacy fields. Applicants must be citizens or permanent residents, with an offer from an accredited institution. The scholarship provides up to $40,000 for tuition, travel, and living expenses. Applications are due in March for Australia to USA and in September for USA to Australia. This initiative strengthens ties and promotes research in critical areas.
Domestic / Homeland Security Education - Higher Education International / Foreign Affairs +7 more

NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed) (357511)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The NIAID Career Transition Award (K22) supports postdoctoral fellows transitioning to independent research positions, fostering their development into successful biomedical scientists. Key deadlines for applications span from February 2025 to June 2027, including specific dates for standard, renewal, and AIDS-related grants. This initiative, funded by the NIH, aims to enhance the career trajectory of emerging researchers in clinical and biomedical fields, ensuring a robust pipeline of innovative scientific talent.
Science Biology Medical Education & Professional Training +3 more

Stassel Education Scholarship

The Alaska Community Foundation
Private
United States
US $1,000

About Us

Overview

The Alaska Community Foundation connects people who care to the causes that make a difference and matter most to them. We encourage and nurture philanthropy through building and managing permanent endowments, convening stakeholders, working with partners to strengthen Alaskan communities, and providing donors with flexible giving options that are strategic to their philanthropic objectives. ACF also manages the Pick.Click.Give. program.

Mission

Inspiring the spirit of giving and connecting people, organizations, and causes to strengthen Alaska’s communities now and forever.

Vision

ACF envisions an Alaska where communities come together and have resources to thrive.

Stassel Education Scholarship Fund

The Stassel Fund was established in memory of Fred L. and Jean N. Stassel who came to Alaska on their honeymoon in 1949, making Anchorage their home for over 60 years until they passed away in 2017 and 2011 respectively. Here they raised 6 children, celebrated Alaska's statehood in 1959, survived the 1964 earthquake, and became active in the community and state. The Fund honors their dedication to education and service to others focusing on creating opportunities for all Alaskans, especially the vulnerable and most in need. Fred and Jean valued education, hard work, integrity, justice, respect, and care for all people. They were both educators, commercial fishers, and very active in social services through the United Methodist Church and other organizations. Fred was very influential in establishing the now-named Credit Union 1, and Jean was active with The League of Women Voters. They would be honored to know that deserving Alaskans were able to pursue their educational goals with the help of scholarships from the Stassel Education Fund.

Education - Higher Education STEM / STEAM Education Mathematics +7 more

Unity for Humanity Grant

Unity Technologies
Corporate
Afghanistan, Algeria +83 more
Up to US $500,000
The Unity for Humanity Grant invites innovative creators to submit impact-driven projects that utilize real-time 3D technology. This annual grant provides funding, technical support, and marketing resources to help bring visionary ideas to life. Projects must align with UN Sustainable Development Goals and demonstrate measurable impact. Eligible submissions include prototypes across various genres, fostering a more inclusive and sustainable world. Join us in empowering changemakers to make a positive global difference.
Human & Social Services Environment Health & Medicine +11 more

FRS: Community Grant Program

Foundation for Rural Service
Private
United States
US $250 - US $5,000
The FRS Community Grant Program supports rural communities served by NTCA members, offering grants up to $5,000 for various local initiatives. Priority is given to projects that promote economic development, education, health, and public service. Eligible applicants must secure a 10% match of the grant amount requested. Ineligible projects include overhead expenses, individuals, and those without secured funding. FRS aims to foster sustainable and engaged rural communities through these efforts.
Rural Development Business Development Economic Services & Development +2 more

Mabel Louise Riley Foundation: Small Grants Fund

Mabel Louise Riley Foundation
Private
Suffolk County, Massachusetts
US $500 - US $5,000
The Mabel Louise Riley Foundation's Small Grants Fund aims to support projects that enhance family life in the Greater Dudley area. Grants range from $500 to $5,000 and prioritize initiatives that foster community engagement, strengthen family connections, and improve neighborhood well-being. Eligible applicants include resident volunteers and local groups, while nonprofit status is not mandatory. The foundation emphasizes activities that promote social cohesion and personal development, ensuring that funds contribute to meaningful community benefits.
Family Services Community Development & Revitalization Greening & Beautification +4 more

Elaine Ehlers Arts Scholarship

Arts Council of the Morris Area
Private
United States
US $5,000
The Elaine Ehlers Arts Scholarship, established in 2002, offers $5,000 to graduating high school seniors in New Jersey who demonstrate artistic excellence in various disciplines such as dance, drama, visual arts, or music. The scholarship is awarded based on a panel's evaluation of work samples and character. This initiative honors Elaine Ehlers' legacy, promoting arts education and supporting students pursuing their creative passions at accredited institutions.
Art & Culture Music Theater +4 more

Eugenie Coladarci Arts Scholarship

Arts Council of the Morris Area
Private
United States
US $1,500
The Eugenie Coladarci Arts Scholarship, offered by Morris Arts, awards $1,500 to graduating high school seniors in New Jersey who demonstrate artistic excellence in various disciplines such as dance, drama, visual arts, or music. Applicants are evaluated by a panel of experts based on their work samples, essays, and dedication to the arts. The scholarship directly supports tuition at the chosen college or arts program, continuing the legacy of Eugenie R. Coladarci, a passionate advocate for young artists.
Art & Culture Academic Scholarship Programs Artist Training & Development +4 more

Curtis Gates Lloyd Research Fellowship

Lloyd Library and Museum
Private
United States
US $2,000 - US $3,000
The Curtis Gates Lloyd Research Fellowship, provided by the Lloyd Library and Museum, supports research in various fields, including botany, conservation, and history of science. This fellowship offers a stipend of $2,000 for local applicants and $3,000 for those from outside the region. To be eligible, applicants must hold at least a Bachelor’s degree and commit to conducting research at the library for a minimum of 20 hours per week. The fellowship duration ranges from one to three months.
History Zoology Mycology +5 more

Career Development Grants

American Association of University Women (AAUW)
Association/Society
United States
Up to US $8,000
The Career Development Grants, offered by the American Association of University Women (AAUW), support women with bachelor's degrees seeking to advance or change careers, particularly in high-growth STEM fields. These grants fund post-bachelor's coursework, including master's degrees or certifications, at accredited institutions. Applicants must demonstrate a commitment to their educational pursuits and meet specific eligibility criteria, such as being enrolled in accredited programs that promote women's participation in underrepresented fields.
Workforce Preparation & Job Readiness Career / College Preparation Education +7 more

Penn National Gaming Foundation Grants

Penn National Gaming
Corporate
Berks County, Pennsylvania, Camden County, Missouri +32 more
Unspecified amount
The Penn National Gaming Foundation Grants support various community initiatives across North America, emphasizing education, health services, and cultural affairs. Launched post-Hurricane Katrina, the foundation aids local nonprofits, enhancing community development, public safety, and veteran support. The grants cater to organizations that address the needs of children, senior citizens, and disadvantaged populations, ensuring a broad impact in areas where Penn National Gaming operates. This commitment reflects the foundation's dedication to uplifting communities and fostering resilience.
Community / Public Safety Diversity, Equity & Inclusion Education - K through 12 +9 more

Modernizing Violent Death and Suicide Surveillance Using the National Violent Death Reporting System (NVDRS)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $966,085
The National Violent Death Reporting System (NVDRS) is a crucial surveillance initiative by the CDC aimed at understanding violent deaths and suicides. This funding opportunity supports state and local entities in modernizing NVDRS, enhancing data collection and reporting processes. Key activities include timely data updates, modernization assessments, and pilot projects for improved data systems. The goal is to create a sustainable national surveillance system that provides reliable data to inform public health actions and enhance violence and suicide prevention efforts.
Computer Science & Engineering Suicide Prevention Violence Prevention

EBCF: Community Donations

Eastern Bank Foundation
Corporate
Bristol County, Massachusetts, Cheshire County, New Hampshire +11 more
US $1,000 - US $10,000
The Eastern Bank Foundation offers community donations to support local needs and events in Massachusetts, New Hampshire, and Rhode Island. Organizations with 501(c)(3) status can apply for donations ranging from $100 to $10,000, with an average of $3,000 to $4,000. Applications are reviewed on a rolling basis, and applicants can expect a decision within 60 days. Note that private foundations and organizations with certain IRS designations are ineligible.
Real Estate & Housing Basic Human Needs Health Care Access & Delivery +4 more

United States Adult Cystic Fibrosis Association (USACFA): Scholarship for the Arts

United States Adult Cystic Fibrosis Association (USACFA)
Association/Society
United States
US $5,000
The United States Adult Cystic Fibrosis Association (USACFA) offers the Scholarship for the Arts, providing $5,000 to two students pursuing degrees in creative fields. Open to applicants from associate to doctoral levels, candidates must demonstrate a minimum GPA of 3.0 and submit proof of enrollment for the academic year. This scholarship honors Helen, a passionate artist and dedicated mother, whose life exemplified resilience and creativity, inspiring future generations in the arts.
Academic Scholarship Programs Art & Culture Art Education +3 more

Thriving Community Impact Fund: Support Grants

GUNDERSEN LUTHERAN MEDICAL FOUNDATION INC
Private
United States
Up to US $2,499
The Thriving Community Impact Fund offers grants up to $2,499 to support local programs that enhance community health and well-being. This initiative by Gundersen Health emphasizes collaboration, focusing on areas such as physical and mental health, poverty alleviation, and neighborhood improvements. Organizations like non-profits and government agencies can apply for funding during a rolling application period, with decisions made monthly. The fund aims to empower communities and address health inequities through impactful partnerships.
Mental Health & Psychiatric Diseases Wellness & Healthy Living Poverty Alleviation & Services +5 more

Kyndryl Foundation Grant

Kyndryl Charitable Foundation
Private
Czech Republic, Hungary +5 more
Unspecified amount
The Kyndryl Foundation Grant aims to empower communities through investments in education, technology, and workforce development. With a focus on cybersecurity and AI skills for underrepresented learners, the foundation fosters balanced partnerships and innovation. It prioritizes transparency and integrity, ensuring grants support long-term impact. This initiative aligns with Kyndryl's mission to create a sustainable future by enhancing access to opportunities and resources for all, thereby promoting diversity and inclusivity in economic growth.
Cybersecurity Workforce Preparation & Job Readiness Career / College Preparation +2 more

Drug-Free Communities (DFC) Support Program – Competing Continuation (Year 6)

US HHS: Substance Abuse and Mental Health Services Administration (SAMHSA)
Federal Government
American Samoa, Guam +4 more
Up to US $125,000
The Drug-Free Communities (DFC) Support Program aims to foster collaboration among community coalitions to combat youth substance use. Established by the Drug-Free Communities Act of 1997, it encourages partnerships among various stakeholders, including governmental and non-profit agencies. The program focuses on reducing substance use among youth and promoting protective factors within communities. This funding opportunity is available for those who have completed the initial funding cycle or experienced funding interruptions, supporting their ongoing efforts to create a healthier environment for youth.
Addiction & Substance Use Disorders Drug Use Disorder Community / Public Safety

Drug-Free Communities (DFC) Support Program – NEW (Year 1) (363353)

US HHS: Substance Abuse and Mental Health Services Administration (SAMHSA)
Federal Government
American Samoa, Guam +4 more
Up to US $125,000
The Drug-Free Communities (DFC) Support Program, initiated by the Drug-Free Communities Act of 1997, aims to bolster community coalitions dedicated to preventing youth substance use. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this program focuses on collaboration among various stakeholders, including government and non-profit entities, to effectively reduce substance abuse among youth and promote protective factors within communities.
Addiction & Substance Use Disorders Drug Use Disorder Community / Public Safety

Operating Grants for Nonprofits in Massachusetts Highlights

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Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Operating Grants for Nonprofits in Massachusetts

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Operating grants for nonprofits in Massachusetts grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

95 Operating grants for nonprofits in Massachusetts over $25K in average grant size

75 Operating grants for nonprofits in Massachusetts over $50K in average grant size

60 Operating grants for nonprofits in Massachusetts supporting general operating expenses

200+ Operating grants for nonprofits in Massachusetts supporting programs / projects

2,000+ Grants on Instrumentl focused on Health & Medicine

700+ Grants on Instrumentl focused on Family Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits in Massachusetts?

Most grants are due in the first quarter.

Q1
32.0%
Q2
24.4%
Q3
18.8%
Q4
24.8%

Typical Funding Amounts

What's the typical grant amount funded for Operating Grants for Nonprofits in Massachusetts?

Grants are most commonly $26,875.

$250 $250 Min.
$26,875 $26.9 K Median
$413,560 $413.6 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for Massachusetts?

Grants are most commonly $124,010.

$124,010

Total Number of Grants

What's the total number of grants in Operating Grants for Nonprofits in Massachusetts year over year?

In 2024, funders in Massachusetts awarded a total of 105,825 grants.

2022 103,608

2023 102,118

2024 105,825

Top Grant Focus Areas

Among all the Operating Grants for Nonprofits in Massachusetts given out in Massachusetts, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Operating Grants for Nonprofits in Massachusetts changing over time?

Funding has increased by 9.89%.

2022 $14,522,602,699

2023 $11,906,472,240
-18.01%

2024 $13,083,681,605
9.89%

Massachusetts Counties That Receive the Most Funding

How does grant funding vary by county?

Suffolk County, Middlesex County, and Norfolk County receive the most funding.

County Total Grant Funding in 2024
Suffolk County $7,016,988,269
Middlesex County $2,770,808,615
Norfolk County $554,651,103
Essex County $369,041,706
Worcester County $299,030,165