Best Middlesex County Grants for Nonprofits in Massachusetts

The MutualOne Charitable Foundation, established in 1998, focuses on promoting charitable, educational, and civic purposes within its market area. Grants of up to $10,000 are available for projects in workforce development, health services, education, community development, and the arts, with a special emphasis on benefiting underserved populations. The foundation prioritizes projects that demonstrate significant community impact and sustainability beyond the grant period.

The B.A.A. Gives Back Grant Program, established by the Boston Athletic Association, supports nonprofit organizations in Massachusetts that promote health and fitness through running. Grants ranging from $5,000 to $15,000 are awarded annually to initiatives that enhance community engagement and wellness. Eligible organizations must be 501(c)(3) registered or public agencies and align with the B.A.A.’s mission to foster healthy lifestyles. This initiative plays a crucial role in expanding access to sports and building vibrant communities across Greater Boston.

The Nordson Corporation Foundation Grant supports educational programs that enhance community quality of life. Focused on fostering self-sufficiency and job readiness, the Foundation values strong relationships and employee engagement. By funding diverse non-profit initiatives, it aims to ensure that all children have access to quality education and that communities thrive through enhanced educational opportunities. Currently, applications are invited only, aligning with their commitment to impactful community partnerships.

The Tufts Community Grants (TCG), launched in 1995, support nonprofit initiatives in Boston, Grafton, Medford, and Somerville. Funded by Tufts University donations, TCG has awarded over $3,000 to 35 local programs in 2025, benefiting more than 150 nonprofits since inception. Grants are aimed at projects that enhance community service and require involvement from Tufts students or staff. Eligible organizations must be 501(c)(3) nonprofits or specific public agencies, focusing on direct community benefits.

The Housing for Everyone Grant Competition, part of the 2026 Initiative, aims to support eviction prevention in low-to moderate-income communities. This 20th annual initiative recognizes the destabilizing impact of eviction and displacement on families, which leads to job loss, school disruptions, and health issues. By funding innovative organizations, the competition seeks to provide stability for renters, enabling them to stay in their homes and communities.

The Bank of America Charitable Foundation focuses on supporting organizations that empower communities through basic needs, income creation, and stable housing. By investing in health and job opportunities, they aim to enhance economic mobility for low- and moderate-income families. Their partnerships target vulnerable populations, ensuring equitable access to resources that foster community vitality and resilience. This initiative emphasizes the importance of stable housing as a foundation for personal and communal growth.

The Jeanne D'Arc Credit Union Donation Request aims to support local non-profits that enhance community well-being through initiatives focused on health, education, and economic revitalization. The foundation encourages applications for event sponsorships and charitable projects that align with their mission of fostering vibrant neighborhoods and providing essential services. Interested organizations should submit requests at least six weeks before their events for timely consideration.

The Cummings $30 Million Grant Program will allocate $30 million to 150 local nonprofits in the Greater Boston area in 2026. This program primarily supports organizations focused on human services, social justice, education, healthcare, and environmental initiatives. Eligible applicants must be based in specific Massachusetts counties and provide services within those areas. The program does not fund requests related to the arts, culture, or animal welfare, ensuring resources are directed to pressing community needs.

About PLTW Biomedical SciencePLTW Biomedical Science students have experience with state-of-the-art tools and techniques that are used by professionals in hospitals and labs every day.Through this partnership, Haemonetics is supporting PLTW grants to schools interested in starting and expanding PLTW programs beginning in the 2027-2028 academic year.Program Requirements:

• Grantee must offer at least one PLTW Biomedical Science course in the 2027-2028 academic year and must offer one additional different course in the 2028-2029 academic year (two different courses in two years).
• Grantee may implement any PLTW Biomedical Science courses of their choosing.
• Grantee must complete two years of reporting.

Grant Distribution Schedule:

• Total Award: $30,000
  • 2027-2028:$15,000
  • 2028-2029: $15,000

The Charles Hayden Foundation Grant supports institutions serving youth and young adults in Boston and metropolitan New York, prioritizing high school to post-secondary success. It emphasizes programs that demonstrate significant impact and measurable progress toward defined goals. The Foundation seeks to ensure that young people gain quality education and career opportunities, and it provides funding for initiatives that foster confidence, informed decision-making, and academic achievement among youth.

The Saab Family Foundation Grant offers support to tax-exempt organizations in Rockingham and Hillsborough Counties in NH, as well as Essex and Middlesex Counties in MA. Established in 2010, the foundation focuses on enhancing the lives of individuals in need, particularly in education, youth services, elderly care, and housing assistance. Grants are aimed at public charities that foster social responsibility and contribute to positive community outcomes.

The Framingham Emergency Relief Fund Grant aims to provide vital financial support to nonprofit organizations in the MetroWest region during crises. This fund addresses emergencies like natural disasters and public health issues by assisting organizations that deliver essential services such as meal preparation, health care, and legal support. It encourages community collaboration, allowing donations from individuals and businesses to enhance the effectiveness of local nonprofits in meeting urgent needs.

Project Lead the Way inc.

School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world. 

PLTW Engineering

PLTW Engineering students adopt a problem-solving mindset, are engaged in compelling, real-world challenges that help them become better collaborators and thinkers, and are prepared with skills to step into any career path they take. Each PLTW Engineering course engages students in interdisciplinary activities like working with a client to design a home, programming electronic devices or robotic arms, or exploring algae as a biofuel source. These activities not only build knowledge and skills in engineering, but also empower students to develop essential skills such as problem solving, critical and creative thinking, communication, collaboration, and perseverance.

PLTW Engineering - Program Expansion (Haemonetics)

Haemonetics is a global medical technology company dedicated to improving the quality, effectiveness and efficiency of health care. Haemonetics strives to make a positive difference in their communities. They support PLTW in order to help foster innovation and career readiness in the communities they serve. 

Through this partnership, Haemonetics is supporting PLTW grants to schools interested in starting and expanding PLTW programs beginning in the 2027-2028 academic year.

The Deborah Munroe Noonan Memorial Fund Grant, established in 1949, supports quality education, family services, and healthcare for mental and physical illness recovery in Greater Boston. It also promotes the arts for under-resourced populations. Organizations in this region can apply for operating or program support, with a deadline of May 1. Grant decisions are communicated by the end of September, allowing multi-year requests and small capital expenses related to programs.

The Hunger Relief Grant Program, established by the Foundation for MetroWest, aims to combat food insecurity across more than 30 communities in the MetroWest region. By providing grants ranging from $1,000 to $10,000, the program supports local nonprofits that address systemic barriers to food access. Eligible organizations must have 501(c)(3) status and serve specific MetroWest towns, ensuring that all residents can achieve food security and eliminate hunger.

Greater Lowell Community Foundation

Founded in 1997, the Greater Lowell Community Foundation is dedicated to improving the quality of life in Greater Lowell and Merrimack Valley.

The Foundation is deeply committed to our local nonprofit community and our grant-making program is focused on assisting nonprofits by fostering collaboration and supporting direct services. The goal of the Foundation is to help our nonprofit partners fulfill their mission more effectively and efficiently. We strive to fund projects that touch many lives and enrich the overall quality of life in our region.

Discretionary Grants Program

The Discretionary Grants Program’s purpose is to improve the quality of life for residents in GLCF’s 21 communities: Acton, Ashby, Ayer, Bedford, Billerica, Burlington, Carlisle, Chelmsford, Concord, Dracut, Dunstable, Groton, Littleton, Lowell, Pepperell, Shirley, Tewksbury, Townsend, Tyngsborough, Westford and Wilmington.

Grant funding from the Greater Lowell Community Foundation’s Discretionary Grants Program includes the following strategic funding categories: Leclair Elder Services, Children’s Services, LGBTQ+.

Please Note: To encourage partnerships between our nonprofits, a nonprofit can apply for a grant category AND be a partner on other grant proposals but not be the lead applicant. Agencies with multiple service sites should submit only one application for all sites.

Leclair Elder Services

The Foundation will award multiple grants of up to $10,000 each to organizations that support services to seniors (55 years+) in our service area. Grant decisions and amounts will be determined based on a variety of factors, including:

• Organization size - understanding the impact of a grant of this size on your organization
• Location(s) of impact - demonstrating commitment to Greater Lowell and role in the region’s social services ecosystem, including strong & established local collaborations and partnerships
• Organization impact and reach - including population served, # of households served, type(s) of programming oKered, etc.
• Organization’s leadership and financial health

The IMA Foundation Grant focuses on empowering communities by supporting nonprofit organizations dedicated to workforce development, financial security for families, and enhancing emergency preparedness. With a mission to provide philanthropic assistance, the foundation seeks partners that align with its vision and operational reach. Organizations must be 501c3 nonprofits and serve areas where IMA has offices, ensuring that their initiatives directly impact youth under 26 years of age.

The TMCity Foundation Grant supports innovative neurocognitive research and mental health initiatives, offering funding between $25,000 and $250,000. Organizations should be 501(c)(3) and focus on healthcare solutions for brain-related ailments. Applications are accepted via a rolling letter of inquiry, followed by a detailed application if interested. The Foundation prioritizes projects based in Southern California and Greater Boston, aiming to advance understanding of mental health through cutting-edge research and technologies.

The A.C. Ratshesky Foundation Grant focuses on supporting economically disadvantaged individuals and families through active learning programs for preteens and teens. It prioritizes initiatives that foster skills development and self-sufficiency, offering grants ranging from $10,000 to $25,000. Eligible organizations must serve the Metro Boston area and demonstrate a commitment to youth development. The foundation does not support individuals or large-scale initiatives but values programs that provide meaningful, hands-on learning experiences.

Medtronic is a global leader in medical technology, dedicated to enhancing healthcare access and supporting the communities it serves. Through its Grants and Donations program, Medtronic provides financial assistance for medical education, independent conferences, and charitable events, emphasizing collaboration with healthcare stakeholders. The program aims to alleviate pain, restore health, and extend life, positively impacting millions of patients worldwide. For more information, visit Medtronic's FAQs on grants and donations.

The Eastern Bank Foundation offers community donations to support local needs and events in Massachusetts, New Hampshire, and Rhode Island. Organizations with 501(c)(3) status can apply for donations ranging from $100 to $10,000, with an average of $3,000 to $4,000. Applications are reviewed on a rolling basis, and applicants can expect a decision within 60 days. Note that private foundations and organizations with certain IRS designations are ineligible.

The Foley Hoag Foundation Grant supports innovative projects aimed at addressing various forms of inequality in Greater Boston, New York City, and Washington, D.C. Established in 1981, it prioritizes small organizations with annual budgets under $750,000. The Foundation encourages community engagement and collaborations that enhance civil rights and equity. Grants are generally awarded for one year and are designed to create impactful changes in the communities served.

2026 Women Working Wonders Grant 

The Women Working Wonders Fund uses a one-step application process and all submissions are to be done electronically, using our online application portal. This year, The Women Working Wonders Fund will award five grants up to $15,000 each to programs/projects that impact the lives of women and girls while advancing your organization’s mission.

The mission of Women Working Wonders Fund, a permanently endowed fund at the Greater Lowell Community Foundation, is to support programs that empower women and girls to effect positive change in the community. Founded and funded by women in 2004, the Women Working Wonders Fund provides grants each year to nonprofit organizations for programs that impact the lives of women and girls in one or more of the three key areas:

Assist women in transition:

Forty years of research shows that social investments in women reduce poverty, raise productivity and accelerate economic growth. This Fund will encourage women to build on their strengths and increase self-worth. In addition, a higher level of self-esteem will be passed along to future generations.

Provide leadership development for women and girls:

The Women Working Wonders Fund will support organizations and activities that contribute to leadership development in women and girls.

Contribute to the beautification of the environment to benefit women and girls:

The Women Working Wonders Fund will support environmental beautification projects that provide a platform for women and girls to showcase their commitment to maintaining the distinct character of their community.

The Babson Foundation's Competitive Grants Program supports entrepreneurship, youth development, and urban environmental improvements in Greater Boston. Focusing on three key areas—entrepreneurship education, community building through urban gardens, and violence reduction—this initiative aims to enhance the quality of life in the region. Eligible organizations must be located within Greater Boston, while specific individuals and certain types of requests, such as summer camps and scholarships, are not funded.

The TD Charitable Foundation has been dedicated to improving community quality of life since 2002, contributing over $254 million to non-profit organizations. They fund initiatives aligned with their corporate citizenship goals, focusing on Better Health, Connected Communities, Financial Security, and Vibrant Planet. Special consideration is given to programs that support inclusivity for diverse and historically underserved communities. Their commitment to enhancing lives through targeted grants reflects their core values and social responsibility.

The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.

The Ramsey McCluskey Family Foundation offers Trilogy Grants to organizations that have received at least three Single-Year grants. Each grant totals $25,000 over three years, with $10,000 in the first year and $7,500 in the following years. Limited to a 50-mile radius from MetroWest Boston, the Foundation prioritizes measurable projects in arts and general education. Only four Trilogy Grants are awarded annually, encouraging sustained educational engagement through hands-on experiences.